Glutamate and disorders of cognition and motivation:
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Format: | Buch |
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Sprache: | English |
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New York, NY
New York Acad. of Sciences
2003
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Schriftenreihe: | Annals of the New York Academy of Sciences
1003 |
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Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | XIV, 487 S. Ill., graph. Darst. |
ISBN: | 1573314765 1573314773 |
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adam_text | ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Volume 1003
November 2003
GLUTAMATE AND DISORDERS OF
COGNITION AND MOTIVATION
Editors
BlTA MOGHADDAM AND MARINA E. WOLF
This volume is the result of a conference entitled Glutamate and Disorders of Cognition
and Motivation held on April 13 15, 2003 in New Haven, Connecticut by the New York
Academy of Sciences and co sponsored by the National Institute of Mental Health and Eli
Lilly and Company.
CONTENTS
Dedication: Patricia S. Goldman Rakic xi
Preface. By Bita Moghaddam and Marina E. Wolf xiii
Part I. Fundamental Aspects of Glutamate Neurotransmission
Synaptic Plasticity and AMPA Receptor Trafficking. By Robert C. Malenka 1
Physiological Roles and Therapeutic Potential of Metabotropic Glutamate
Receptors. By P. JEFFREY CONN 12
Genomics and Variation of Ionotropic Glutamate Receptors. By ROBERT H.
Lipsky and David Goldman 22
Part II. Interactions between Glutamate and Monoamine Systems
Anatomical Substrates for Glutamate Dopamine Interactions: Evidence for
Specificity of Connections and Extrasynaptic Actions. By SUSAN R.
Sesack, Da vidB.Carr.NataliaOmelchenko, and Aline Pinto... 36
Electrophysiological Interactions between Striatal Glutamatergic and
Dopaminergic Systems. By Anthony R. West, Stan B. Floresco,
Ali Charara, J. Amiel Rosenkranz, and Anthony A. Grace 53
Part III. Glutamate and Schizophrenia
Molecular Abnormalities of the Glutamate Synapse in the Thalamus in
Schizophrenia. By James H. Meador Woodruff, Sarah M. Clinton,
Monica Beneyto, and Robert E. McCullumsmith 75
Glutamate Receptors and Transporters in the Hippocampus in Schizophrenia.
By?aul J. Harrison, Amanda J. Law, and Sharon L. Eastwood .... 94
Altered Cortical Glutamate Neurotransmission in Schizophrenia: Evidence
from Morphological Studies of Pyramidal Neurons. By David A. Lewis,
Leisa A. Glantz, Joseph N. Pierri, and Robert A. Sweet 102
Evaluating Glutamatergic Transmission in Schizophrenia. By Carol A.
Tamminga, Adrienne C. Lahti, Deborah R. Medoff, Xue Min Gao,
and Henry H. Holcomb 113
The NMDA Receptor Hypofunction Model of Psychosis. By Nuri B. Farber . 119
Glutamatergic Animal Models of Schizophrenia. By Bita Moghaddam and
Mark E. Jackson 131
Glutamate, Dopamine, and Schizophrenia: From Pathophysiology to
Treatment. By Marc Laruelle, Lawrence S. Kegeles, and
Anissa Abi Dargham 138
Part IV. Glutamate and Addiction
Glutamate Mediated Plasticity in Corticostriatal Networks: Role in Adaptive
Motor Learning. By Ann E. Kelley, Matthew E. Andrzejewski,
Anne E. Baldwin, Pepe J. Hernandez, and Wayne E. Pratt 159
Glutamate Transmission and Addiction to Cocaine. By Peter W. Kalivas,
Krista McFarland, Scott Bowers, Karen Szumlinski,
Zheng Xiong Xi, and David Baker 169
NMDA Receptor Antagonism and the Ethanol Intoxication Signal: From
Alcoholism Risk to Pharmacotherapy. By John H. Krystal, Ismene L.
Petrakis, Evgeny Krupitsky, Christian Schutz, Louis Trevisan,
and D. Cyril D Souza 176
Short and Long Term Modulation of Synaptic Inputs to Brain Reward Areas
by Nicotine. By Zara M. Fagen, Huibert D. Mansvelder, J. Russel
Keath, and Daniel S. McGehee 185
Glutamatergic Transmission in Opiate and Alcohol Dependence. By George
Robert Siggins, Gilles Martin, Marisa Roberto, Zhiguo Nie,
Samuel Madamba, and Luis de Lecea 196
Exogenous and Endogenous Cannabinoids Control Synaptic Transmission in
Mice Nucleus Accumbens. By David Robbe, Gerard Alonso, and
Olivier J. Manzoni 212
Plastic Control of Striatal Glutamatergic Transmission by Ensemble Actions
of Several Neurotransmitters and Targets for Drugs of Abuse. By David
M. Lovinger, John G. Partridge, and Ka Choi Tang 226
Mechanisms by which Dopamine Receptors May Influence Synaptic Plasticity.
By Marina E. Wolf, Simona Mangiavacchi, and Xiu Sun 241
Part V. Glutamate and Mood Disorders
Glutamate and Depression: Clinical and Preclinical Studies. By Ian A. Paul
and Phil Skolnick 250
Regulation of Cellular Plasticity Cascades in the Pathophysiology and
Treatment of Mood Disorders: Role of the Glutamatergic System. By
Carlos A. Zarate Jr., Jing Du, Jorge Quiroz, Neil A. Gray,
Kirk D. Denicoff, Jaskaran Singh, Dennis S. Charney, and
Husseini K. Manji 273
Clinical Studies Implementing Glutamate Neurotransmission in Mood Dis¬
orders. By Gerard Sanacora, Douglas L. Rothman, Graeme
Mason, and John H. Krystal 292
Part VI. Glutamate Based Pharmacotherapies
A Role for Noradrenergic Transmission in the Actions of Phencyclidine and
the Antipsychotic and Antistress Effects of mGlu2/3 Receptor Agonists.
By Chad J. Swanson and Darryle D. Schoepp 309
Converging Evidence of NMDA Receptor Hypofunction in the Patho¬
physiology of Schizophrenia. By Joseph T. Coyle, Guochuan Tsai,
and Donald Goff 318
Glutamatergic Agents for Cocaine Dependence. By Charles Dackis and
Charles O Brien 328
Part VII. Poster Papers
Dopamine Acetylcholine Interactions in the Modulation of Glutamate
Release. By Marco Atzori, Patrick Kanold, Juan Carlos Pineda,
and Jorge Flores Hernandez 346
Af Acetyl Cysteine Induced Blockade of Cocaine Induced Reinstatement. By
David A. Baker, Krista McFarland, Russell W. Lake, Hui Shen,
Shigenobu Toda, and Peter W. Kalivas 349
AMP A and NMDA Associated Postsynaptic Protein Expression in the
Human Dorsolateral Prefrontal Cortex. By Monica Beneyto and
James H. Meador Woodruff 352
AGS3: A G Protein Regulator of Addiction Associated Behaviors.
By M. S. Bowers, R. W. Lake, K. McFarland, Y. K. Peterson,
S. M. Lanier, C. C. Lapish, and P. W. Kalivas 356
Changes in Electrophysiological Properties of Nucleus Accumbens Neurons
Depend on the Extent of Behavioral Sensitization to Chronic Metham
phetamine. By Anne Marie Brady, Stanley D. Glick, and
PATRICK) O DONNELL 358
Evaluation of NMDA Receptors in Vivo in Schizophrenic Patients with
[123I]CNS 1261 and SPET: Preliminary Findings. By Rodrigo A.
Bressan, Kjell Erlandsson, Rachel S. Mulligan, RogerN. Gunn,
Vincent J. Cunningham, Jonathan Owens, Peter J. Ell, and
Lyn S. Pilowsky 364
Effects of Naloxone Precipitated Morphine Withdrawal on Glutamate
Mediated Signaling in Striatal Neurons in Vitro. By Elena H.
Chartoff, Maria Papadopoulou, Christine Konradi, and
William A. Carlezon Jr 368
Opposite Effects of GluRl and PKA Resistant GluRl Overexpression in the
Ventral Tegmental Area on Cocaine Reinforcement. By Kwang Ho
Choi, Zia Rahman, Scott Edwards, Stephanie Hall, Rachael L.
Neve, and David W. Self 372
Expression of ARHGEF11 mRNA in Schizophrenic Thalamus.
By Genoveva Davidkova, Robert E. McCullumsmith, and
James H. Meador Woodruff 375
Structurally Dissimilar Antimanic Agents Modulate Synaptic Plasticity by
Regulating AMP A Glutamate Receptor Subunit GluRl Synaptic
Expression. By Jing Du, Neil A. Gray, Cynthia Falke, Peixiong
Yuan, Steven Szabo, and Husseini K. Manji 378
Cocaine Induced Expression Differences in Glutamate Receptor Subunits and
Transporters in Amygdalae of Taste Aversion Prone and Taste
Aversion Resistant Rats. By R. L. Elkins, T. E. Orr, J. L. Rausch,
Y. J. Fei, G. F. Carl, S. H. Hobbs, J. J. Buccafusco, and
G. L. Edwards 381
Cocaine Induced Expression Differences in PSD 95/SAP 90 Associated
Protein 4 and in Ca2+/Calmodulin Dependent Protein Kinase Subunits in
Amygdalae of Taste Aversion Prone and Taste Aversion Resistant
Rats. By R. L. Elkins, T. E. Orr, J. L. Rausch, Y. J. Fei, G. F. Carl,
S. H. Hobbs, J. J. Buccafusco, and G. L. Edwards 386
Rapid AMPAR/NMDAR Response to Amphetamine: A Detectable Increase
in AMPAR/NMDAR Ratios in the Ventral Tegmental Area Is Detectable
after Amphetamine Injection. By L. J. Faleiro, S. Jones, and
J. A. Kauer 391
Nucleus Accumbens Homer Proteins Regulate Behavioral Sensitization to
Cocaine. By M. Behnam Ghasemzadeh, Lindsay K. Permenter,
Russell W. Lake, and Peter W. Kalivas 395
Altered Prefrontal Cortex Nucleus Accumbens Information Processing in a
Developmental Animal Model of Schizophrenia. By Yukiori GOTO and
Patricio O Donnell 398
Lithium Regulates Total and Synaptic Expression of the AMPA Glutamate
Receptor GluR2 in Vitro and in Vivo. By Neil A. Gray, Jing Du,
Cynthia S. Falke, Peixiong Yuan, and Husseini K. Manji 402
Prefrontal Group II Metabotropic Glutamate Receptor Activation Decreases
Performance on a Working Memory Task. By Mary L. Gregory,
Nicholas E. Stech, Russell W. Owens, and Peter W. Kalivas 405
The Effects of Selective Orbitofrontal Cortex Lesions on the Acquisition and
Performance of Cue Controlled Cocaine Seeking in Rats. By Daniel M.
HUTCHESON AND BARRY J. EVERITT 410
In Vivo Characterization of Changes in Glycine Levels Induced by GlyTl
Inhibitors. By Kirk W. Johnson, Amy Clemens Smith, George
Nomikos, Richard Davis, Lee Phebus, Harlan Shannon, Patrick
Love, Ken Perry, Jason Katner, Frank Bymaster, Hong Yu, and
Beth J. Hoffman 412
Metabotropic Glutamate 5 Receptor Antagonist MPEP Decreased Nicotine
and Cocaine Self Administration but Not Nicotine and Cocaine Induced
Facilitation of Brain Reward Function in Rats. By P. J. Kenny,
N. E. Paterson, B. Boutrel, S. Semenova, A. A. Harrison,
F. Gasparini, G. F. Koob, P. D. Skoubis, and A. Markou 415
Elucidation of Homer la Function in the Nucleus Accumbens Using Adeno
virus Gene Transfer Technology. By M. S. Bowers, R. W. Lake,
S. Rubinchik, J Y. Dong, and P. W. Kalivas 419
Glutamate/Monoamine Interactions in the Limbic Thalamus.
By Antonieta Lavin 422
Changes in NMDA Receptor Subunit mRNAs and Cyclophilin mRNA during
Development of the Human Hippocampus. By Amanda J. La w, Cynthia
Shannon Weickert, Maree J. Webster, Mary M. Herman, Joel E.
Kleinman, and Paul J. Harrison 426
Blockade of the GlyTl Glycine Transporter Prolongs Response to VTA
Stimulation in Nucleus Accumbens Neurons. By Barbara Lewis and
Patricio O Donnell 431
Modulation of Inhibitory Transmission in the Rat Globus Pallidus by Activa¬
tion of mGluR4. By Michael J. Marino, Ornella Valenti, Julie A.
O Brien, David L. Williams Jr., and P. Jeffrey Conn 435
Expression of Transcripts for the Vesicular Glutamate Transporters in the
Human Medial Temporal Lobe. By Robert E. McCullumsmith and
James H. Meador Woodruff 438
Metabotropic Glutamate Receptor Regulation of Extracellular Glutamate
Levels in the Prefrontal Cortex. By ROBERTO I. Melendez and
Peter W. Kalivas 443
Cystine/Glutamate Antiporter Regulation of Vesicular Glutamate Release.
By Megan M. Moran, Roberto Melendez, David Baker, Peter W.
Kalivas, and Jeremy K. Seamans 445
Expression of the NR3 A Subunit of the NMDA Receptor in Human Fetal
Brain. By Helena T. Mueller and James H. Meador Woodruff 448
Coupling of Glutamatergic Neurotransmission and Neuronal Glucose Oxida¬
tion over the Entire Range of Cerebral Cortex Activity. By An ANT B.
Patel, Robin A. de Graaf, Graeme F. Mason, Douglas L. Rothman,
Robert G. Shulman, and Kevin L. Behar 452
Real Time in Vivo Measures of L Glutamate in the Rat Central Nervous
System Using Ceramic Based Multisite Microelectrode Arrays.
By F. Pomerleau, B. K. Day, P. Huettl, J. J. Burmeister, and
G. A. Gerhardt 454
TRH and Related Peptides: Homeostatic Regulators of Glutamate Transmis¬
sion? By A. Sattin A. E. Pekary, R. L. Lloyd, M. Paulson,
J. A. Meyerhoff, P. M. Hinkle, and K. Faull 458
L Homocysteine Sulfinic Acid and L Homocysteic Acid Stimulate Phos
phoinositide Hydrolysis in Rat Cortical Neurons. By Qi Shi, Sandra J.
HUFEISEN, JARDA T. WROBLEWSKI, JOSEPH H. NADEAU, AND
Bryan L. Roth 461
Distinct Contributions of Glutamate Receptor Subtypes to Cognitive Set
Shifting Abilities in the Rat. By MARK R. STEFANI AND
BlTA MOGHADDAM 464
Evidence for a Relationship between Group 1 mGluR Hypofunction and
Increased Cocaine and Ethanol Sensitivity in Homer2 Null Mutant Mice.
By Karen K. Szumlinski, Shigenobu Toda, Lawrence D. Middaugh,
Paul F. Worley, and Peter W. Kalivas 468
Bidirectional Modulation of Cystine/Glutamate Exchanger Activity in
Cultured Cortical Astrocytes. By Xing Chun Tang and
Peter W. Kalivas 472
Dopamine Glutamate Interactions in the Control of Cell Excitability in
Medial Prefrontal Cortical Pyramidal Neurons from Adult Rats.
By Kuei Yuan Tseng and Patricio O Donnell 476
Modulation of Excitatory Transmission onto Midbrain Dopaminergic
Neurons of the Rat by Activation of Group III Metabotropic Glutamate
Receptors. By Ornella Valenti, Michael J. Marino, and
P. Jeffrey Conn 479
Difference in mGluR5 Interaction between Positive Allosteric Modulators
from Two Structural Classes. By DAVID L. WILLIAMS JR., Julie A.
O Brien, Wei Lemaire, Tsing Bau Chen, Raymond S. L. Chang,
MarleneA.Jacobson,SookheeN.Ha,DavidD.Wisnoski,CraigW.
LlNDSLEY, CYRILLE SUR, MARK E. DUGGAN, DOUGLAS J. PETTIBONE,
and P. Jeffrey Conn 481
Index of Contributors 485
Financial assistance was received from:
Co sponsors
• NATIONAL INSTITUTE OF MENTAL HEALTH—NATIONAL
INSTITUTES OF HEALTH
• ELI LILLY AND COMPANY
Contributors
• MERCK RESEARCH LABORATORIES
• PFIZER GLOBAL RESEARCH AND DEVELOPMENT
The New York Academy of Sciences believes it has a responsibility to provide an open
forum for discussion of scientific questions. The positions taken by the participants in
the reported conferences are their own and not necessarily those of the Academy. The
Academy has no intent to influence legislation by providing such forums.
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genre | (DE-588)1071861417 Konferenzschrift 2003 New Haven Conn. gnd-content Electronic books |
genre_facet | Konferenzschrift 2003 New Haven Conn. Electronic books |
id | DE-604.BV017634963 |
illustrated | Illustrated |
indexdate | 2024-07-09T19:20:10Z |
institution | BVB |
isbn | 1573314765 1573314773 |
language | English |
lccn | 2003023023 |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-010606943 |
oclc_num | 53156792 |
open_access_boolean | |
owner | DE-20 DE-12 |
owner_facet | DE-20 DE-12 |
physical | XIV, 487 S. Ill., graph. Darst. |
publishDate | 2003 |
publishDateSearch | 2003 |
publishDateSort | 2003 |
publisher | New York Acad. of Sciences |
record_format | marc |
series | Annals of the New York Academy of Sciences |
series2 | Annals of the New York Academy of Sciences |
spelling | Glutamate and disorders of cognition and motivation ed. by Bita Moghaddam ... New York, NY New York Acad. of Sciences 2003 XIV, 487 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Annals of the New York Academy of Sciences 1003 Acide glutamique - Actes de congrès Acide glutamique rasuqam Cognitieve stoornissen gtt Cognition - Congrès Effet physiologique rasuqam Glutamaat gtt Glutamates - Actes de congrès Glutamique, Acide - Congrès ram Glutamique, Acide - Effets physiologiques - Congrès Motivation (Psychologie) - Congrès Motivation (psychologie) - Congrès ram Motivation rasuqam Processus cognitif rasuqam Récepteur glutamate - Actes de congrès Trouble de la cognition rasuqam Troubles cognitifs - Actes de congrès Troubles de la cognition - Congrès ram Troubles mentaux - Actes de congrès Cognition Congresses Glutamic Acid metabolism Congresses Glutamic Acid physiology Congresses Glutamic acid Physiological effect Congresses Mental Disorders etiology Congresses Mental Disorders physiopathology Congresses Motivation (Psychology) Congresses Receptors, Glutamate physiology Congresses Kognition (DE-588)4031630-0 gnd rswk-swf Motivation (DE-588)4040364-6 gnd rswk-swf Glutamate (DE-588)4157708-5 gnd rswk-swf Psychische Störung (DE-588)4047686-8 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 2003 New Haven Conn. gnd-content Electronic books Glutamate (DE-588)4157708-5 s Kognition (DE-588)4031630-0 s Motivation (DE-588)4040364-6 s DE-604 Psychische Störung (DE-588)4047686-8 s b DE-604 Moghaddam, Bita Sonstige oth Annals of the New York Academy of Sciences 1003 (DE-604)BV002532608 1003 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010606943&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Glutamate and disorders of cognition and motivation Annals of the New York Academy of Sciences Acide glutamique - Actes de congrès Acide glutamique rasuqam Cognitieve stoornissen gtt Cognition - Congrès Effet physiologique rasuqam Glutamaat gtt Glutamates - Actes de congrès Glutamique, Acide - Congrès ram Glutamique, Acide - Effets physiologiques - Congrès Motivation (Psychologie) - Congrès Motivation (psychologie) - Congrès ram Motivation rasuqam Processus cognitif rasuqam Récepteur glutamate - Actes de congrès Trouble de la cognition rasuqam Troubles cognitifs - Actes de congrès Troubles de la cognition - Congrès ram Troubles mentaux - Actes de congrès Cognition Congresses Glutamic Acid metabolism Congresses Glutamic Acid physiology Congresses Glutamic acid Physiological effect Congresses Mental Disorders etiology Congresses Mental Disorders physiopathology Congresses Motivation (Psychology) Congresses Receptors, Glutamate physiology Congresses Kognition (DE-588)4031630-0 gnd Motivation (DE-588)4040364-6 gnd Glutamate (DE-588)4157708-5 gnd Psychische Störung (DE-588)4047686-8 gnd |
subject_GND | (DE-588)4031630-0 (DE-588)4040364-6 (DE-588)4157708-5 (DE-588)4047686-8 (DE-588)1071861417 |
title | Glutamate and disorders of cognition and motivation |
title_auth | Glutamate and disorders of cognition and motivation |
title_exact_search | Glutamate and disorders of cognition and motivation |
title_full | Glutamate and disorders of cognition and motivation ed. by Bita Moghaddam ... |
title_fullStr | Glutamate and disorders of cognition and motivation ed. by Bita Moghaddam ... |
title_full_unstemmed | Glutamate and disorders of cognition and motivation ed. by Bita Moghaddam ... |
title_short | Glutamate and disorders of cognition and motivation |
title_sort | glutamate and disorders of cognition and motivation |
topic | Acide glutamique - Actes de congrès Acide glutamique rasuqam Cognitieve stoornissen gtt Cognition - Congrès Effet physiologique rasuqam Glutamaat gtt Glutamates - Actes de congrès Glutamique, Acide - Congrès ram Glutamique, Acide - Effets physiologiques - Congrès Motivation (Psychologie) - Congrès Motivation (psychologie) - Congrès ram Motivation rasuqam Processus cognitif rasuqam Récepteur glutamate - Actes de congrès Trouble de la cognition rasuqam Troubles cognitifs - Actes de congrès Troubles de la cognition - Congrès ram Troubles mentaux - Actes de congrès Cognition Congresses Glutamic Acid metabolism Congresses Glutamic Acid physiology Congresses Glutamic acid Physiological effect Congresses Mental Disorders etiology Congresses Mental Disorders physiopathology Congresses Motivation (Psychology) Congresses Receptors, Glutamate physiology Congresses Kognition (DE-588)4031630-0 gnd Motivation (DE-588)4040364-6 gnd Glutamate (DE-588)4157708-5 gnd Psychische Störung (DE-588)4047686-8 gnd |
topic_facet | Acide glutamique - Actes de congrès Acide glutamique Cognitieve stoornissen Cognition - Congrès Effet physiologique Glutamaat Glutamates - Actes de congrès Glutamique, Acide - Congrès Glutamique, Acide - Effets physiologiques - Congrès Motivation (Psychologie) - Congrès Motivation (psychologie) - Congrès Motivation Processus cognitif Récepteur glutamate - Actes de congrès Trouble de la cognition Troubles cognitifs - Actes de congrès Troubles de la cognition - Congrès Troubles mentaux - Actes de congrès Cognition Congresses Glutamic Acid metabolism Congresses Glutamic Acid physiology Congresses Glutamic acid Physiological effect Congresses Mental Disorders etiology Congresses Mental Disorders physiopathology Congresses Motivation (Psychology) Congresses Receptors, Glutamate physiology Congresses Kognition Glutamate Psychische Störung Konferenzschrift 2003 New Haven Conn. Electronic books |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010606943&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
volume_link | (DE-604)BV002532608 |
work_keys_str_mv | AT moghaddambita glutamateanddisordersofcognitionandmotivation |