PET and PET-CT in oncology: 60 tables
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Berlin [u.a.]
Springer
2004
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | Includes bibliographical references and index |
| Physical Description: | XIV, 350 S. Ill., graph. Darst. |
| ISBN: | 354043125X |
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Record in the Search Index
| _version_ | 1804130226965315584 |
|---|---|
| adam_text | Parti: Basics
1 Physical Principles, Dedicated/
Coincidence PET 3
S. ZlEGLER
1.1 Physics Background 3
1.2 Detectors for PET 4
1.3 Tomograph Design 5
2 Dual Modality PET/CT Acquisition Systems
for Clinical Oncology 9
T. Beyer and D. W. Townsend
2.1 Adding Anatomical
to Functional Information 9
2.2 Anato metabolic Imaging: The Proof of
principle for Dual Modality Imaging 11
2.3 PET/CT Design Considerations: The Second
Generation of PET/CT Tomographs 15
2.4 Experiences with Existing PET/CT
Technology 19
2.5 Recent Developments and Trends
for Tomorrow 25
3 Transport and Metabolism
of Glucose and FDG 30
P. Oehr
3.1 Biological Functions
of Carbohydrate Metabolism 30
3.2 Metabolism of Glucose, 2 DG, 2 FDG
and3 FDG 31
3.3 FDG Uptake 33
4 Radiopharmaceutical Production
and Safety of [18F]FDG 43
P. Oehr
4.1 Radiopharmaceutical Chemistry
of[18F]FDG 43
4.2 [18F]FDG Pharmacokinetics, Toxicity
and Interactions 45
4.3 [18F]FDG Activity Dosages
and Radiation Exposure 46
4.4 Conclusions 47
5 Image Fusion 49
U. PlETRZYK
5.1 Introduction 49
5.2 Basic Remarks 49
5.3 Properties of PET, SPECT, CT and MR
Images Relevant for Image Fusion 50
5.4 Technical Issues in Image Fusion 50
5.5 Image Fusion in Brain Imaging 53
5.6 Image Fusion Strategies
for Extra cranial Images 54
5.7 Combined Devices for Functional
Anatomical Imaging (PET/CT) 55
6 PET Scanner Quality Control 59
T. G. TURKINGTON
6.1 Quality Control Issues 59
6.2 Basic Ring Function and the Sinogram 59
6.3 Impact of Malfunctioning Detectors 62
6.4 A Simple Daily Protocol 63
6.5 Quantitative Accuracy 63
6.6 Determining Whether or Not to Scan 64
Part II: Experimental Oncology
7 Introduction to Experimental PET
in Oncology 67
P. Oehr
7.1 PET and Molecular Imaging 67
7.2 Assay Models for Experimental PET 67
7.3 Conclusions 71
8 PET in Cell Cultures: Oncology, Genetics,
and Therapy 73
P. Oehr, N. Gilbert, H. Lemmoch,
M. Ludwig, R. Wagner, H. Schuller,
and H. Rink
8.1 Introduction 73
8.2 Material and Methods 73
8.3 Results 74
8.4 Discussion 74
8.5 Conclusion 75
VIII Contents
9 Small Animal PET in Oncology 77
M. Honer, M. Bruhlmeier,
I. NOVAK HOFER, AND S. AMETAMEY
9.1 Dedicated Small Animal PET Cameras 77
9.2 Applications of Small Animal PET
in Oncology 79
10 Small Animal PET in Neuro oncology
and Gene Therapy 87
A.H. Jacobs and W. D. Heiss
10.1 Introduction 87
10.2 Gliomas General and Molecular
Aspects 87
10.3 Gene Therapy for Gliomas Current
Status and Future Perspectives 88
10.4 Small Animal PET Imaging
of Endogenous Gene Expression
for Characterization of Target Tissue 88
10.5 Small Animal PET Imaging of Expression
of Exogenously Introduced Genes 90
10.6 Summary and Conclusion 94
Part III: Clinical Applications
11 PET/CT: Clinical Considerations 101
A. Bockisch, L. Freudenberg,
G. Antoch, and St. Muller
11.1 Introduction 101
11.2 Present State and Use of PET/CT 102
11.3 Clinical Value of PET/CT at Present 102
11.4 Patient Selection and Clinical Protocols
for PET/CT Scanning 105
11.5 Clinical Impact of PET/CT 105
12 Brain Tumors 113
T. Z. Wong, G. J. van der Westhuizen,
AND R. E. COLEMAN
12.1 Incidence, Etiology, Epidemiology 113
12.2 Histopathological Classification 113
12.3 Imaging of Brain Tumors 114
12.4 FDG PET Imaging of Brain Tumors 114
12.5 Indications for FDG PET Imaging
of Brain Tumors 115
12.6 Other PET Tracers 119
12.7 Summary and Outlook 121
12.8 Technical Recommendations 121
13 Head and Neck Tumors 127
H. Bender and H. J. Straehler Pohl
13.1 Incidence, Etiology and Epidemiology 127
13.2 Histopathology 127
13.3 Conventional Diagnostic Procedures 128
13.4 Functional Imaging/FDG PET 129
13.5 Summary and Outlook 133
13.6 Technical Recommendations 134
14 Thyroid Carcinomas 137
F. Grunwald and M. Diehl
14.1 Clinical Background 137
14.2 Therapy 137
14.3 UseofFDGPET 139
14.4 Indications 144
14.5 Results and Interpretation 145
14.6 Limits of Interpretation 146
15 Lung Cancer 149
J. F. Vansteenkiste and S.S. Stroobants
15.1 Incidence, Etiology and Epidemiology 149
15.2 Histopathological Classification 149
15.3 Conventional Diagnostic Procedures 150
15.4 PET 153
15.5 Indications for PET Practical Clinical
Guidelines 158
15.6 New Tracer Developments 160
15.7 Summary and Outlook 161
15.8 Technical Recommendations 161
16 Breast Cancer 167
H. Palmedo
16.1 Incidence and Epidemiology 167
16.2 Histopathological Classification, Pathology
and Prognosis of Breast Cancer 167
16.3 Conventional Diagnostic Procedures
and Treatment Strategies 168
16.4 PET in Breast Cancer 171
16.5 Indications 175
16.6. Technical Recommendations 176
17 Pancreatic Cancer 179
D. Delbeke
17.1 Epidemiology and Histopathological
Types 179
17.2 Conventional Diagnostic Imaging
Modalities 179
17.3 FDG PET Imaging 180
17.4 FDG PET for Evaluation of Islet Cells and
Other Endocrine Tumors of the Pancreas ... 183
17.5 Summary 184
18 Gastro Esophageal Cancer , 187
P. Flamen and L. Mortelmans
18.1 Introduction 187
18.2 PET: Current Status 189
18.3 Indications of PET 199
18.4 New Tracer Developments 199
18.5 Summary 200
18.6 Technical Recommendations 200
19 Liver Cancer 203
J. H. Risse
19.1 Incidence, Etiology and Epidemiology 203
19.2 Histopathological Classification 203
19.3 Conventional Diagnostic Procedures
and Treatment Strategies 204
19.4 PET: Current Status in Liver Cancer 205
19.5 Judgement of Indications of PET
in Liver Cancer 209
19.6 New Tracer Developments 209
19.7 Summary and Outlook 209
19.8 Technical Recommendations 209
20 Colorectal Cancer 213
M. T. KlTAPCI AND R. E. COLEMAN
20.1 Introduction 213
20.2 Diagnosis 215
20.3 FDG PET Imaging for Colorectal
Cancer: Current State 216
20.4 Impact on Patient Management 223
20.5 Assessment of Prognosis
and Cost Effectiveness 223
20.6 Limitations 223
20.7 Summary 224
20.8 New Tracers 224
20.9 Technical Recommendations 224
21 Ovarian Cancer 227
M. ZlMNY
21.1 Incidence, Etiology, Epidemiology 227
21.2 Histological Classification 227
21.3 Diagnosis and Treatment
of Ovarian Cancer 227
21.4 Positron Emission Tomography 228
21.5 Summary 232
21.6 Technical Recommendations 232
22 Cancer of the Uterus 237
M. J. Reinhardt
22.1 Preface 237
22.2 Epidemiology 237
22.3 Pattern of Spread and Histology 237
Contents IX
22.4 Diagnosis, Staging and Prognostic Factors .. 237
22.5 Evidence for the Use of 18F FDG PET
in the Management of Cervical Cancer 238
22.6 Technical Recommendations 240
22.7 Conclusion 240
23 PET in Bladder, Renal,
and Prostate Cancer 243
M. Seltzer and O. Shvarts
23.1 Introduction 243
23.2 Bladder Cancer 243
23.3 Renal Cancer 244
23.4 Prostate Cancer 245
23.5 Summary 247
24 Testicular Tumors 251
P.Albers
24.1 Incidence, Epidemiology and Clinical
Diagnosis 251
24.2 Pathological Diagnosis and Classification .. 251
24.3 PET in Diagnosis and Treatment 253
24.4 Summary and Future Directions 256
25 Malignant Melanoma 259
P. Paquet, R. Hustinx, P. Rigo,
AND G.E. PlERARD
25.1 Introduction 259
25.2 Rationale for Using 18 FDG
as a Radiotracer in Melanoma 260
25.3 Sensitivity and Specificity of 18 FDG PET
in Cutaneous Melanoma 261
25.4 FDG PET Versus Conventional Imaging
in Melanoma 262
25.5 Pitfalls of FDG PET in Melanoma 263
25.6 FDG PET in Ocular Melanoma 264
25.7. New Radiotracers for Melanoma 264
25.8 Conclusion 264
26 Malignant Lymphomas 267
C. Menzel
26.1 Hodgkin s disease 267
26.2 Non Hodgkin s Lymphoma 270
27 Musculoskeletal Tumors 275
A.K. Buck, H. Schirrmeister,
and S.N. Reske
27.1 Incidence, Etiology, Epidemiology 275
27.2 Histopathological Classification 276
27.3 Conventional Diagnostic Procedures
and Treatment Strategies 277
27.4 Positron Emission Tomography 278
X Contents
27.5 Judgement of Indications for FDG PET 280
27.6 New Tracer Developments 281
27.7 Summary and Outlook 281
27.8 Technical Recommendations 283
28 Skeletal imaging with F 18 285
H. Palmedo
28.1 Background 285
28.2 Conventional Screening
for Bone Metastases 287
28.3 PET with F 18 Sodium Fluoride
for Metastatic Bone Disease 287
28.4 Technical Recommendations 289
29 PET in Surgery 291
S. Yasuda, K. Nakai, M. Ide,
S. Kawada, and A. Shohtsu
29.1 Introduction 291
29.2 Advantages of FDG PET 291
29.3 Limitations of FDG PET 291
29.4 Applications of FDG PET in Surgery 292
29.5 Summary 299
30 PET and Radiotherapy 303
Val J. Lowe
30.1 Background 303
30.2 PET Before Radiation Therapy 303
30.3 PET During Radiation Therapy 303
30.4 Deoxygenation and PET 304
30.5 PET Imaging After Completion
of Radiation Therapy 304
30.6 Diagnosing Recurrent Disease with PET ... 306
30.7 Timing of PET After Radiation Therapy 306
30.8 Summary 308
31 Cancer Screening with 18F FDG PET 309
K. Nakai, S. Yasuda, M. Ide,
S. Kawada, and A. Shohtsu
31.1. Background 309
31.2. Subjects and Methods 309
31.3. Results 309
31.4 Cancer Screening 310
31.5. Conclusions 320
32 Cost Effectiveness Studies of PET
in Oncology 321
K. A. Miles and L. B. Connelly
32.1 Introduction 321
32.2 Definitions 321
32.3 Techniques for Assessing Cost
Effectiveness 324
32.4 Cost Effectiveness Studies of PET
in Oncology 326
32.5 Translating the Results of Cost
Effectiveness Studies to Other Countries ... 328
32.6 Summary 329
33 Reimbursement (EU and USA)
33.1 PET Reimbursement: Europe 331
M. DlETLEIN
33.2 PET Reimbursement: United States 335
R. E. COLEMAN AND RUTH D. TeSAR
Subject Index 339
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| spelling | PET and PET-CT in oncology 60 tables P. Oehr ... [eds.] Berlin [u.a.] Springer 2004 XIV, 350 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Includes bibliographical references and index Krebs Medizin (DE-588)4073781-0 gnd rswk-swf Positronen-Emissions-Tomografie (DE-588)4129799-4 gnd rswk-swf Computertomografie (DE-588)4113240-3 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Krebs Medizin (DE-588)4073781-0 s Positronen-Emissions-Tomografie (DE-588)4129799-4 s DE-604 Computertomografie (DE-588)4113240-3 s Oehr, Peter 1942- Sonstige (DE-588)120928973 oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010490259&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | PET and PET-CT in oncology 60 tables Krebs Medizin (DE-588)4073781-0 gnd Positronen-Emissions-Tomografie (DE-588)4129799-4 gnd Computertomografie (DE-588)4113240-3 gnd |
| subject_GND | (DE-588)4073781-0 (DE-588)4129799-4 (DE-588)4113240-3 (DE-588)4143413-4 |
| title | PET and PET-CT in oncology 60 tables |
| title_auth | PET and PET-CT in oncology 60 tables |
| title_exact_search | PET and PET-CT in oncology 60 tables |
| title_full | PET and PET-CT in oncology 60 tables P. Oehr ... [eds.] |
| title_fullStr | PET and PET-CT in oncology 60 tables P. Oehr ... [eds.] |
| title_full_unstemmed | PET and PET-CT in oncology 60 tables P. Oehr ... [eds.] |
| title_short | PET and PET-CT in oncology |
| title_sort | pet and pet ct in oncology 60 tables |
| title_sub | 60 tables |
| topic | Krebs Medizin (DE-588)4073781-0 gnd Positronen-Emissions-Tomografie (DE-588)4129799-4 gnd Computertomografie (DE-588)4113240-3 gnd |
| topic_facet | Krebs Medizin Positronen-Emissions-Tomografie Computertomografie Aufsatzsammlung |
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