One hundred years of chromosome research and what remains to be learned:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Dordrecht [u.a.]
Kluwer Acad. Publ.
2003
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | "Bibliography:" p. [185]-189 -- Includes bibliographical references (p. [191]-194) and indexes |
| Beschreibung: | VII, 219 S. zahlr. Ill., graph. Darst. |
| ISBN: | 1402014392 |
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| 650 | 4 | |a Geschichte | |
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| 650 | 4 | |a Genetic Research |x history | |
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Datensatz im Suchindex
| _version_ | 1804130211748380672 |
|---|---|
| adam_text | ONE HUNDRED YEARS OF
CHROMOSOME RESEARCH
AND
WHAT REMAINS TO BE LEARNED
BY
A UMA-DE-FARIA
Professor Emeritus
of Molecular Cytogenetics
at Lund University,
Lund, Sweden
N3
KLUWER ACADEMIC PUBLISHERS
DORDRECHT / BOSTON / LONDON
Contents
Introduction 1-2
PART I
NINE PERIODS OF CHROMOSOME RESEARCH: 1795 TO 2010
First Period 1795-1850 5-7
The precursors: Better microscopes allowed reaching the cell level
Second Period 1850-1900 9-12
The pioneers: The discovery of the chromosome was a by-product of microbiology
Third Period 1900-1930 13-15
The era of abstract genetics: Order in embryonic development led to the finding of order in
inheritance
Fourth Period 1930-1950 17-20
The impact of physics and chemistry on genetics: World War II encouraged the development of
microbial genetics
Fifth Period 1950-1970 21-25
Radioisotopes and electron microscopy became a most fruitful combination: Molecular biology
received its main impulse from disciplines outside genetics
Sixth Period 1970-1980 27-30
The mechanisms of cancer and of development were sought at the DNA level: Biotechnology
emerged as a new field as genetics created its own weapons
Seventh Period 1980-1990 31-34
Neurobiology reached the molecular level: Artificial chromosomes and gene therapy became a
reality
Eighth Period 1990-2001 35-37
The genome of humans and of other organisms was sequenced: The age of multilaboratory
collaboration was established
Ninth Period 2001-2010 39-43
The post-genome era: The task that lies ahead
PART II
THE TECHNOLOGY THAT ALLOWED THE STUDY OF THE CHROMOSOME: 1900 TO 2001
From staining methods to DNA sequencing 47-56
PART III
IN SEARCH OF THE EUKARYOTIC CHROMOSOME
Main stages in the discovery of the cell s structure and function 59-62
The nucleus versus the cytoplasm Which was most important? 63-64
VI
The description of cell division: An impressive transformation was accompanied by directed
cellular movements 65-66
Meiosis was another unexpected property: The cell could reduce its chromosome number 67-70
The maintenance of identity of the chromosome during interphase was accompanied by constancy
and variability of pattern in different tissues 71-72
PART IV
THE THREE UNIQUE REGIONS OF THE EUKARYOTIC CHROMOSOME
The centromere: A Pandora s box of unearthed properties 75-79
The telomere: Not just a terminus station 81-84
The nucleolus organizer: Nothing in the cell is comparable to it 85-88
PART V
NO CHROMOSOME CAN FUNCTION OUTSIDE A CELL
Cytoskeleton: A disgusting artifact became an important cell edifice 91-92
Nuclear envelope: The nucleus disclosed its outer structure 93-94
Centriole: An enigmatic cell invention 95-96
Endoplasmic reticulum and Golgi apparatus: The building of membranes permitted molecular
reactions to occur in defined sequences 97-98
Cell membrane and cell wall: The cell became an individualized entity 99-101
PART VI
SPECIFIC TYPES OF CHROMOSOMES
Chromosomes of viruses: An early or a late form of chromosome?
Chromosomes of bacteria: Nearly naked DNA could become independent
Chromosomes of mitochondria: Intruders invaded the cell
Chromosomes of chloroplasts: Additional genomes entered the cell
105-107
109-111
113-115
117-119
PART VII
THE ANTITHETICAL PROPERTIES OF THE CHROMOSOME
Physico-chemical processes are antithetical
THE CHROMOSOME S RIGIDITY
Maintenance of organization: The protozoan versus the human chromosome
Maintenance of the chromosome phenotype
Maintenance of gene order
127-131
133-136
137-140
Vll
Maintenance of function 141-143
The periodicity of chromosome transformations 145-148
THE CHROMOSOME S PLASTICITY
Structural change 151-153
Change of pattern 155-156
Change in size 157-158
Change in number 159-160
Change in function 161-165
PART VIII
CHROMOSOME MODELS AND WHAT THEY DO NOT TELL US
The models 169-173
What the models do not tell us 175-176
PART IX
EPILOGUE
Where did the chromosome come from? 179-181
Where is the chromosome going? 183-184
Bibliography: A list of selected books that have dealt with the chromosome during the period
1870-2001 - 185-189
References: Cited works between 1990 and 2001 191-194
Sources of Illustrations 195-
Subject index
Author inded
|
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| discipline | Biologie |
| era | Geschichte 1795-2003 gnd |
| era_facet | Geschichte 1795-2003 |
| format | Book |
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| indexdate | 2024-07-09T19:17:26Z |
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| spelling | Lima-de-Faria, Antonio Verfasser aut One hundred years of chromosome research and what remains to be learned by A. Lima-de-Faria Dordrecht [u.a.] Kluwer Acad. Publ. 2003 VII, 219 S. zahlr. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier "Bibliography:" p. [185]-189 -- Includes bibliographical references (p. [191]-194) and indexes Geschichte 1795-2003 gnd rswk-swf Chromosomes Chromosomes - Recherche - Histoire Geschichte Chromosomes Research History Genetic Research history History, 19th Century History, 20th Century Chromosom (DE-588)4010162-9 gnd rswk-swf Forschung (DE-588)4017894-8 gnd rswk-swf Chromosom (DE-588)4010162-9 s Forschung (DE-588)4017894-8 s Geschichte 1795-2003 z DE-604 HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010479273&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Lima-de-Faria, Antonio One hundred years of chromosome research and what remains to be learned Chromosomes Chromosomes - Recherche - Histoire Geschichte Chromosomes Research History Genetic Research history History, 19th Century History, 20th Century Chromosom (DE-588)4010162-9 gnd Forschung (DE-588)4017894-8 gnd |
| subject_GND | (DE-588)4010162-9 (DE-588)4017894-8 |
| title | One hundred years of chromosome research and what remains to be learned |
| title_auth | One hundred years of chromosome research and what remains to be learned |
| title_exact_search | One hundred years of chromosome research and what remains to be learned |
| title_full | One hundred years of chromosome research and what remains to be learned by A. Lima-de-Faria |
| title_fullStr | One hundred years of chromosome research and what remains to be learned by A. Lima-de-Faria |
| title_full_unstemmed | One hundred years of chromosome research and what remains to be learned by A. Lima-de-Faria |
| title_short | One hundred years of chromosome research and what remains to be learned |
| title_sort | one hundred years of chromosome research and what remains to be learned |
| topic | Chromosomes Chromosomes - Recherche - Histoire Geschichte Chromosomes Research History Genetic Research history History, 19th Century History, 20th Century Chromosom (DE-588)4010162-9 gnd Forschung (DE-588)4017894-8 gnd |
| topic_facet | Chromosomes Chromosomes - Recherche - Histoire Geschichte Chromosomes Research History Genetic Research history History, 19th Century History, 20th Century Chromosom Forschung |
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