The human nasolacrimal ducts: 8 tables
Saved in:
| Main Author: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Berlin [u.a.]
Springer
2003
|
| Series: | Advances in anatomy, embryology and cell biology
170 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XI, 106 S. Ill., graph. Darst. |
| ISBN: | 3540440763 |
Staff View
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| 245 | 1 | 0 | |a The human nasolacrimal ducts |b 8 tables |c Friedrich Paulsen |
| 264 | 1 | |a Berlin [u.a.] |b Springer |c 2003 | |
| 300 | |a XI, 106 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
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Record in the Search Index
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| adam_text |
CONTENTS
1
INTRODUCTION
AND
QUESTIONS
.
1
1.1
INTRODUCTION
.
1
1.2
QUESTIONS
.
5
2
MATERIALS
AND
METHODS
.
7
2.1
HUMAN
MATERIAL
.
7
2.1.1
CADAVERS
.
7
2.1.2
SPECIMENS
OBTAINED
AT
SURGERY
.
7
2.1.3
ENDONASAL
DACRYOCYSTORHINOSTOMY
-
BIOPSY
TECHNIQUE
.
8
2.2
ANIMAL
MATERIAL
.
8
2.2.1
CADAVERS
.
8
2.2.2
LIVING
ANIMALS
.
9
2.3
LIGHT
MICROSCOPY
.
9
2.4
LECTIN
STAINING
.
9
2.5
IMMUNOHISTOCHEMISTRY
.
10
2.5.1
EXTRACELLULAR
MATRIX
.
10
2.5.2
TREFOIL
FACTOR
PEPTIDES
.
11
2.5.3
ANTIMICROBIAL
PEPTIDES
.
11
2.5.4
DEFENCE
CELLS
.
12
2.5.5
NERVOUS
TISSUE
.
12
2.6
SCANNING
ELECTRON
MICROSCOPY
.
13
2.7
TRANSMISSION
ELECTRON
MICROSCOPY
.
13
2.8
CORROSION
VASCULAR
CASTS
.
13
2.9
REVERSE
TRANSCRIPTION
POLYMERASE
CHAIN
REACTION
AND
WESTERN
BLOT
.
14
2.9.1
CELL
CULTURE
.
14
2.9.2
TOTAL
RNA
PURIFICATION
AND
CDNA
SYNTHESIS
.
14
2.9.3
RT-PCR
OF
TREFOILFACTOR
PEPTIDES
.
14
2.9.4
ANTISERA
AND
WESTERN
BLOT
ANALYSIS
OF
TFFS
.
15
2.9.5
RT-PCR
OF
ANTIMICROBIAL
PEPTIDES
.
15
2.10
ANIMAL
INVESTIGATIONS/EXPERIMENTS
.
16
2.10.1
ANIMAL
EXPERIMENTS
WITH
RATS
.
16
2.10.1.1
IODINATION
OF
BOVINE
SERUM
ALBUMIN
.
16
2.10.1.2
ABSORPTION
EXPERIMENTS
.
16
2.10.1.3
FRACTIONATION
OF
RADIOACTIVITY
IN
THE
SERUM
.
16
2.10.1.4
LIGHT
MICROSCOPY
AND
AUTORADIOGRAPHY
.
17
2.10.2
COMPARATIVE
ANATOMY
.
17
2.10.2.1
OCULAR
SAMPLE
PREPARATION
AND
LIGHT
MICROSCOPY
FOR
COMPARATIVE
ANATOMY
.
17
2.10.2.2
SCANNING
ELECTRON
MICROSCOPY
FOR
COMPARATIVE
ANATOMY
.
17
2.10.3
ANIMAL
EXPERIMENTS
WITH
RABBITS
.
18
2.10.3.1
DETERMINATION
OF
3
H-CORTISOL
UPTAKE
.
18
2.10.3.2
LIGHT
MICROSCOPY
AND AUTORADIOGRAPHY
.
18
3
RESULTS
.
19
3.1
THE
EPITHELIUM
AND
THE
UNDERLYING
LAMINA
PROPRIA
OF
THE
NASOLACRIMAL
DUCTS
.
19
3.1.1
STRUCTURE
OF
THE
EPITHELIUM
.
19
3.1.1.1
HISTOLOGY
.
19
3.1.1.2
ULTRASTRUCTURE
OF
THE
EPITHELIUM
.
21
3.1.2
RECEPTOR
BINDING
OF
CARBOHYDRATE-SPECIFIC
LECTINS
TO
THE
EPITHELIUM
.
22
3.1.3
TREFOIL
FACTOR
PEPTIDES
IN
THE
EPITHELIUM
.
23
3.1.3.1
RT-PCR
ANALYSIS.
23
3.1.3.2
WESTERN
BLOT
ANALYSIS
.
23
3.1.3.3
GENERAL
HISTOLOGY
AND
IMMUNOHISTOCHEMISTRY.
.
24
3.1.4
LOCALISATION
OF
ANTIMICROBIAL
PEPTIDES
.
27
3.1.4.1
RT-PCR
ANALYSIS
.
27
3.1.4.2
ANTIMICROBIAL
PEPTIDE
IMMUNOSTAINING
.
29
3.1.5
MUCOSA
ASSOCIATED
LYMPHOID
TISSUE
.
31
3.1.5.1
DISTRIBUTION
AND
ORGANISATION
IN
"
HEALTHY
"
(CADAVERS)
NASOLACRIMAL
SYSTEMS
.
31
3.1.5.2
DISTRIBUTION
AND
ORGANISATION
IN
"
INFLAMED
"
(SURGICALLY
OBTAINED)
NASOLACRIMAL
SYSTEMS
.
33
3.1.5.3
ORGANISATION
OF
MALT
IN
CADAVERS
AND
SURGICALLY
OBTAINED
SPECIMENS
.
35
3.1.5.4
IGA
IMMUNOSTAINING
IN
"
HEALTHY
"
(CADAVERS)
NASOLACRIMAL
SYSTEMS
.
35
3.1.5.5
IGA
IMMUNOSTAINING
IN
"
INFLAMED
"
(SURGICALLY
OBTAINED)
NASOLACRIMAL
SYSTEMS
.
35
3.2
THE
MEMBRANOUS
PART
OF
THE
NASOLACRIMAL
DUCTS
38
3.2.1
THE
VASCULAR
SYSTEM
.
38
3.2.2
INNERVATION
OF
THE
VASCULAR
SYSTEM
AND
THE
SEROMUCOUS
GLANDS
OF
THE
NASOLACRIMAL
DUCTS
.
41
3.2.2.1
DISTRIBUTION
OF
NEURONAL
MARKERS
.
41
3.2.2.2
ULTRASTRUCTURE
OF
THE
NERVOUS
TISSUE
.
44
3.2.3
STRUCTURAL
ANALYSIS
OF
THE
LAMINA
PROPRIA
IN
THE
NASOLACRIMAL
DUCTS
.
45
3.3
ABSORPTION
EXPERIMENTS
IN
THE
NASOLACRIMAL
DUCTS
.
46
3.3.1
ABSORPTION
EXPERIMENTS
IN
RATS
.
46
3.3.1.1
KINETICS
OF
UPTAKE
OF
RADIOACTIVITY
INTO
THE
SERUM
46
3.3.1.2
ANALYSIS
OF
THE
INCORPORATED
RADIOACTIVITY
IN
THE
SERUM
.
46
VIII
3.3.1.3
LIGHT
MICROSCOPY
AND
AUTORADIOGRAPHY
.
46
3.3.2
COMPARATIVE
ANATOMY
OF
THE
NASOLACRIMAL
DUCTS
50
3.3.2.1
COMPARATIVE
HISTOLOGY
.
50
3.3.2.2
COMPARATIVE
SCANNING
ELECTRON
MICROSCOPY
(HUMAN
AND
RABBIT)
.
52
3.3.3
ABSORPTION
EXPERIMENTS
IN
RABBITS
.
52
3.3.3.1
KINETICS
OF
UPTAKE
OF
RADIOACTIVE
CORTISOL
INTO
BLOOD/SERUM
.
52
3.3.3.2
LIGHT
MICROSCOPY
AND
AUTORADIOGRAPHY
(RABBIT)
53
3.4
PATHOLOGIC
FINDINGS
IN
DACRYOSTENOSIS
.
53
3.4.1
HISTOLOGICAL
FINDINGS
.
55
3.4.2
ULTRASTRUCTURAL
FINDINGS
.
57
4
DISCUSSION
.
59
4.1
MECHANISMS
OF
IMMUNE
DEFENCE
IN
THE
NASOLACRIMAL
DUCTS
.
59
4.1.1
THE
FUNCTION
OF
THE
EPITHELIUM
LINING
THE
NASOLACRIMAL
DUCTS
.
59
4.1.1.1
LECTIN
BINDING
SITES
AND
MUCINS
.
59
4.1.1.2
TFF
PEPTIDES
.
61
4.1.1.3
ANTIMICROBIAL
PEPTIDES
.
63
4.1.2
SPECIFIC
IMMUNE
DEFENCE
BY
MALT
.
66
4.1.2.1
MALT
OF
THE
NASOLACRIMAL
DUCTS
.
66
4.1.2.2
LOSS
OF
TALT
IN
ASSOCIATION
WITH
THE
SCARRING
OF
SYMPTOMATIC
DACRYOSTENOSIS
.
68
4.2
MECHANISMS
REGULATING
TEAR
FLOW
THROUGH
THE
NASOLACRIMAL
DUCTS
.
70
4.2.1
REGULATION
OF
TEAR
FLOW
BY
THE
CAVERNOUS
BODY
.
70
4.2.2
INNERVATION
OF
THE
CAVERNOUS
BODY
AND
THE
SEROMUCOUS
GLANDS
.
72
4.2.3
EXPERIMENTAL
INFLUENCE
ON
THE
REGULATION
OF
TEAR
FLOW
BY
THE
CAVERNOUS
BODY
.
74
4.2.4
BIOMECHANICS
OF
TEAR
FLOW
.
74
4.3
ABSORPTION
OF
TEAR
FLUID
COMPONENTS
.
75
4.3.1
WHAT
HAPPENS
TO
TEARS
INSIDE
THE
NASOLACRIMAL
DUCTS?
.
75
4.3.2
THE
NASOLACRIMAL
SYSTEM
OF
THE
RABBIT
SHOWS
HIGH
HOMOLOGY
WITH
THE
HUMAN
NASOLACRIMAL
DUCTS
.
77
4.3.3
THE
RABBIT
-
ANIMAL
MODEL
FOR
THE
ABSORPTION
OF
LIPOPHILIC
SUBSTANCES
FROM
TEAR
FLUID
BY
THE
EPITHELIUM
OF
THE
NASOLACRIMAL
DUCTS
.
77
4.4
INSIGHTS
INTO
THE
PATHOPHYSIOLOGY
OF
PRIMARY
ACQUIRED
DACRYOSTENOSIS
.
79
4.5
CONSIDERATIONS
ON
THE
RELATIONSHIP
BETWEEN
DRY
EYE
AND
THE
NASOLACRIMAL
DUCTS
.
82
4.5.1
ABSORPTION
OF
TEAR
FLUID
IN
THE
NASOLACRIMAL
DUCTS
-
FEEDBACK
SIGNAL
FOR
TEAR
FLUID
PRODUCTION?
.
82
IX
4.5.2
TEAR
DUCT-ASSOCIATED
LYMPHOID
TISSUE
-
ENTRANCE
SIDE
FOR
THE
IMMUNOLOGICAL
EVENTS
IN
DRY
EYE?
.
83
5
OUTLOOK
.
87
6
SUMMARY
.
89
REFERENCES
.
91
SUBJECT
INDEX
.
105
X |
| any_adam_object | 1 |
| author | Paulsen, Friedrich 1965- |
| author_GND | (DE-588)124866697 |
| author_facet | Paulsen, Friedrich 1965- |
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| ctrlnum | (OCoLC)633947561 (DE-599)BVBBV014849587 |
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| id | DE-604.BV014849587 |
| illustrated | Illustrated |
| indexdate | 2024-08-23T00:24:26Z |
| institution | BVB |
| isbn | 3540440763 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-010046066 |
| oclc_num | 633947561 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR |
| owner_facet | DE-355 DE-BY-UBR |
| physical | XI, 106 S. Ill., graph. Darst. |
| publishDate | 2003 |
| publishDateSearch | 2003 |
| publishDateSort | 2003 |
| publisher | Springer |
| record_format | marc |
| series | Advances in anatomy, embryology and cell biology |
| series2 | Advances in anatomy, embryology and cell biology |
| spelling | Paulsen, Friedrich 1965- Verfasser (DE-588)124866697 aut The human nasolacrimal ducts 8 tables Friedrich Paulsen Berlin [u.a.] Springer 2003 XI, 106 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Advances in anatomy, embryology and cell biology 170 Anatomie (DE-588)4001895-7 gnd rswk-swf Nase (DE-588)4171180-4 gnd rswk-swf Ductus nasolacrimalis (DE-588)4736949-8 gnd rswk-swf Tränendrüse (DE-588)4185823-2 gnd rswk-swf Nase (DE-588)4171180-4 s Tränendrüse (DE-588)4185823-2 s Anatomie (DE-588)4001895-7 s DE-604 Ductus nasolacrimalis (DE-588)4736949-8 s Advances in anatomy, embryology and cell biology 170 (DE-604)BV002528506 170 DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010046066&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Paulsen, Friedrich 1965- The human nasolacrimal ducts 8 tables Advances in anatomy, embryology and cell biology Anatomie (DE-588)4001895-7 gnd Nase (DE-588)4171180-4 gnd Ductus nasolacrimalis (DE-588)4736949-8 gnd Tränendrüse (DE-588)4185823-2 gnd |
| subject_GND | (DE-588)4001895-7 (DE-588)4171180-4 (DE-588)4736949-8 (DE-588)4185823-2 |
| title | The human nasolacrimal ducts 8 tables |
| title_auth | The human nasolacrimal ducts 8 tables |
| title_exact_search | The human nasolacrimal ducts 8 tables |
| title_full | The human nasolacrimal ducts 8 tables Friedrich Paulsen |
| title_fullStr | The human nasolacrimal ducts 8 tables Friedrich Paulsen |
| title_full_unstemmed | The human nasolacrimal ducts 8 tables Friedrich Paulsen |
| title_short | The human nasolacrimal ducts |
| title_sort | the human nasolacrimal ducts 8 tables |
| title_sub | 8 tables |
| topic | Anatomie (DE-588)4001895-7 gnd Nase (DE-588)4171180-4 gnd Ductus nasolacrimalis (DE-588)4736949-8 gnd Tränendrüse (DE-588)4185823-2 gnd |
| topic_facet | Anatomie Nase Ductus nasolacrimalis Tränendrüse |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010046066&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV002528506 |
| work_keys_str_mv | AT paulsenfriedrich thehumannasolacrimalducts8tables |