Fluorescence diagnosis and photodynamic therapy of skin diseases: atlas and handbook
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Wien [u.a.]
Springer
2003
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | Getr. Zählung zahlr. Ill. |
| ISBN: | 3211838279 |
Staff View
MARC
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| 245 | 1 | 0 | |a Fluorescence diagnosis and photodynamic therapy of skin diseases |b atlas and handbook |c Clemens Fritsch ; Thomas Ruzicka |
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| 650 | 4 | |a Fluorescence | |
| 650 | 4 | |a Photochemotherapy | |
| 650 | 4 | |a Skin Neoplasms |x diagnosis | |
| 650 | 4 | |a Skin Neoplasms |x drug therapy | |
| 650 | 4 | |a Skin |x Diseases |x Diagnosis | |
| 650 | 4 | |a Skin |x Diseases |x Photochemotherapy | |
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Record in the Search Index
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|---|---|
| adam_text | A Introduction and Historical Landmarks 1
A.I Definition of the Photodynamic Action 1
A.2 Optimum Photosensitizing Agent for Photodynamic Action 1
A.2.1 Hematoporphyrin Derivative (HpD) and Porfimer Sodium (Photofrin) 1
A.2.2 Porphines 2
A.2.3 Phthalocyanines 2
A.2.4 Chlorine Derivatives 2
A.2.5 Lutetium texaphyrin (Lu Tex) 3
A.2.6 Porphycenes 3
A.2.7 Other Photosensitizers 3
A.2.8 Endogenous Porphyrins 3
A3 Definition of Fluorescence Detection with ALA Induced Porphyrins (FDAP) 4
A.3.1 Physical Background of the Fluorescence in FDAP 6
A.4 Mechanisms of Action in PDT 7
B 5 Aminolevulinic Acid (ALA) 9
B.I Chemistry of ALA and ALA Methylester (ALA) 9
B.2 Metabolism of ALA 10
B.3 Pharmacodynamics of ALA 12
B.3.1 Systemic Administration of ALA 12
B.3.2 Topical Application of ALA 16
C Light Used in FDAP and PDT 19
D Unresolved Issues in FDAP and PDT 21
E Fluorescence Detection of ALA induced Porphyrins (FDAP) 23
E.I FDAP: Evaluation of the ALA Induced Fluorescence in Skin Diseases 23
F Ex vivo Investigations on ALA induced Porphyrins 33
F.I Porphyrin Accumulation in Cells (in vitro) 33
F.2 Porphyrin Accumulation in Skin Tumors, Colon and Bronchial Carcinomas
after Administration of ALA (ex vivo) 34
G In vivo Investigations on ALA Induced Porphyrin /FDAP 37
G.I FDAP: Kinetics of ALA Induced Porphyrins in Human Cutaneous Tumors,
Psoriasis Lesions and Normal Skin 37
G.2 FDAP: Kinetics of Porphyrin Accumulation in Solar Keratoses:
ALA versus ALA Methylester 39
G.3 FDAP: Use of the in vivo Fluorescence for Surgical Planning 43
G.4 FDAP: Evaluation of the Optimum Photosensitizing Substance or its Prodrug 44
G.5 FDAP: Evaluation of the Optimum Exciting Light Source 46
G.6 FDAP: Correlation of in vivo Tumor Fluorescence and Histopathology 46
G.7 FDAP: Course of FDAP in Relation to the Number of PDT Sessions 50
Contents VI
H The Clinical Use of FDAP 55
H.I FDAP in Clinically Well defined Tumors 55
H.2 FDAP in Clinically Ill defined Lesions 56
H.3 FDAP in Pretreated or Damaged Skin 59
H.4 Limitations of FDAP 61
H.5 Usefulness of FDAP in Guiding Tumor Therapies 62
I Photodynamic Therapy in Cutaneous Diseases 65
1.1 PDT: Evaluation of the Efficacy in Solar Keratoses 65
1.2 PDT: Evaluation of the Efficacy in Bowen s Disease 71
1.3 PDT: Evaluation of the Efficacy in Basal Cell Carcinoma 72
1.4 PDT: Evaluation of the Efficacy in Squamous Cell Carcinoma 76
1.5 PDT: Evaluation of the Efficacy in Psoriatic Lesions 78
1.6 PDT: Evaluation of the Efficacy in Selected Cutaneous Diseases 84
1.6.1 PDT in Skin Cancers and Precanceroses Others than Discussed Above 85
1.6.2 PDT in Tumors of the Oral Mucosa 86
1.6.3 PDT in Non neoplastic Skin Diseases 86
1.6.4 PDT in Non dermatological Indications 89
1.7 PDT: Evaluation of the Optimum Photosensitizing Substance or its Prodrug 89
1.8 PDT: Evaluation of the Optimum Exciting Light Source 91
J General Discussion 97
J.I FDAP: Indications and Limits 97
J.2 PDT: Indications and Limits 101
J.3 Safety and Tolerability of ALA PDT 107
J.4 Regulatory Affairs Concerning Aminolevulinic Acid 108
J.5 Regulatory Affairs Concerning Aminolevulinic Acid Methylester 108
K Conclusion 109
L Summary 111
Acknowledgements 113
Bibliography 115
|
| any_adam_object | 1 |
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| author_variant | c f cf t r tr |
| building | Verbundindex |
| bvnumber | BV014724805 |
| callnumber-first | R - Medicine |
| callnumber-label | RL120 |
| callnumber-raw | RL120.P46 |
| callnumber-search | RL120.P46 |
| callnumber-sort | RL 3120 P46 |
| callnumber-subject | RL - Dermatology |
| classification_rvk | YF 1800 |
| ctrlnum | (OCoLC)53286108 (DE-599)BVBBV014724805 |
| dewey-full | 616.50631 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.50631 |
| dewey-search | 616.50631 |
| dewey-sort | 3616.50631 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Book |
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| id | DE-604.BV014724805 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T19:05:28Z |
| institution | BVB |
| isbn | 3211838279 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-009978180 |
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| physical | Getr. Zählung zahlr. Ill. |
| publishDate | 2003 |
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| publisher | Springer |
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| spelling | Fritsch, Clemens Verfasser aut Fluorescence diagnosis and photodynamic therapy of skin diseases atlas and handbook Clemens Fritsch ; Thomas Ruzicka Wien [u.a.] Springer 2003 Getr. Zählung zahlr. Ill. txt rdacontent n rdamedia nc rdacarrier Fluorescence Photochemotherapy Skin Neoplasms diagnosis Skin Neoplasms drug therapy Skin Diseases Diagnosis Skin Diseases Photochemotherapy Fotodynamische Therapie (DE-588)4312776-9 gnd rswk-swf Hautkrankheit (DE-588)4023852-0 gnd rswk-swf Fluoreszenzspektroskopie (DE-588)4017701-4 gnd rswk-swf Hautkrankheit (DE-588)4023852-0 s Fotodynamische Therapie (DE-588)4312776-9 s DE-604 Fluoreszenzspektroskopie (DE-588)4017701-4 s Ruzicka, Thomas Verfasser aut HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009978180&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Fritsch, Clemens Ruzicka, Thomas Fluorescence diagnosis and photodynamic therapy of skin diseases atlas and handbook Fluorescence Photochemotherapy Skin Neoplasms diagnosis Skin Neoplasms drug therapy Skin Diseases Diagnosis Skin Diseases Photochemotherapy Fotodynamische Therapie (DE-588)4312776-9 gnd Hautkrankheit (DE-588)4023852-0 gnd Fluoreszenzspektroskopie (DE-588)4017701-4 gnd |
| subject_GND | (DE-588)4312776-9 (DE-588)4023852-0 (DE-588)4017701-4 |
| title | Fluorescence diagnosis and photodynamic therapy of skin diseases atlas and handbook |
| title_auth | Fluorescence diagnosis and photodynamic therapy of skin diseases atlas and handbook |
| title_exact_search | Fluorescence diagnosis and photodynamic therapy of skin diseases atlas and handbook |
| title_full | Fluorescence diagnosis and photodynamic therapy of skin diseases atlas and handbook Clemens Fritsch ; Thomas Ruzicka |
| title_fullStr | Fluorescence diagnosis and photodynamic therapy of skin diseases atlas and handbook Clemens Fritsch ; Thomas Ruzicka |
| title_full_unstemmed | Fluorescence diagnosis and photodynamic therapy of skin diseases atlas and handbook Clemens Fritsch ; Thomas Ruzicka |
| title_short | Fluorescence diagnosis and photodynamic therapy of skin diseases |
| title_sort | fluorescence diagnosis and photodynamic therapy of skin diseases atlas and handbook |
| title_sub | atlas and handbook |
| topic | Fluorescence Photochemotherapy Skin Neoplasms diagnosis Skin Neoplasms drug therapy Skin Diseases Diagnosis Skin Diseases Photochemotherapy Fotodynamische Therapie (DE-588)4312776-9 gnd Hautkrankheit (DE-588)4023852-0 gnd Fluoreszenzspektroskopie (DE-588)4017701-4 gnd |
| topic_facet | Fluorescence Photochemotherapy Skin Neoplasms diagnosis Skin Neoplasms drug therapy Skin Diseases Diagnosis Skin Diseases Photochemotherapy Fotodynamische Therapie Hautkrankheit Fluoreszenzspektroskopie |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009978180&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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