Infections and the cardiovascular system: new perspectives
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
New York [u.a.]
Kluwer Academic/Plenum
2003
|
| Series: | Emerging infectious diseases of the 21st century
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | Includes bibliographical references and index |
| Physical Description: | XII, 270 S. Ill., graph. Darst. |
| ISBN: | 0306474042 |
Staff View
MARC
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| 245 | 1 | 0 | |a Infections and the cardiovascular system |b new perspectives |c ed. by I. W. Fong |
| 264 | 1 | |a New York [u.a.] |b Kluwer Academic/Plenum |c 2003 | |
| 300 | |a XII, 270 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
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| 490 | 0 | |a Emerging infectious diseases of the 21st century | |
| 500 | |a Includes bibliographical references and index | ||
| 650 | 4 | |a Cardiovascular Diseases |x etiology | |
| 650 | 4 | |a Cardiovascular system |x Infections | |
| 650 | 4 | |a Communicable Diseases |x etiology | |
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Record in the Search Index
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| adam_text | Contents
Section I
Traditional Infections Affecting the Cardiovascular System
Chapter 1
New Insights and Updates for Established Entities
1.1. Introduction 3
1.2. Infective Endocarditis 3
1.2.1. Advances in the Diagnosis of Infective
Endocarditis 5
1.2.2. Update on Prevention of Infective Endocarditis 7
1.2.3. Advances in the Treatment of Infective
Endocarditis 10
1.3. Updates on Rheumatic Fever and Rheumatic Carditis 12
1.3.1. Update on the Diagnosis of Rheumatic Fever 13
1.3.2. Advances in the Pathogenesis of Rheumatic
Fever and Carditis 13
1.3.3. Host Susceptibility to Rheumatic Fever and Carditis 15
1.3.4. Update of Rheumatic Fever Prophylaxis 15
1.3.5. Progress in Myocarditis 16
1.3.6. Causation of Myocarditis 17
1.3.7. Pathobiology of Myocarditis 18
1.3.8. Treatment of Myocarditis 20
vii
viii Contents
1.4. Cardiac Device Infection—Updates 21
References 23
Chapter 2
Atherosclerosis and Inflammation
2.1. Introduction 33
2.2. Pathology of Atherosclerosis 34
2.2.1. Inflammatory Response 35
2.2.2. Components of Atherosclerotic Lesion 36
2.3. Histological Classification of Atherosclerotic Lesions 39
2.4. Systemic Markers of Inflammation and Cardiovascular Disease.... 42
2.4.1. Fibrinogen 43
2.4.2. C Reactive Protein 45
2.4.3. Leucocyte Count 46
2.4.4. Albumin 47
2.4.5. Serum Amyloid A Protein 48
2.4.6. Phospholipase A2 49
2.4.7. Cytokines 50
2.4.8. Adhesion Molecules 51
2.5. Conclusion 53
References 54
Chapter 3
Traditional Risk Factors and Newly Recognized Emerging
Risk Factors for Cardiovascular Disease
3.1. Introduction 63
3.2. Hypercholesterolemia 63
3.3. Dyslipidemias 65
3.4. Smoking 67
3.5. Hypertension 68
3.6. Diabetes Mellitus 69
3.7. Obesity 70
3.8. Genetics 71
3.9. New Risk Factors for Atherosclerotic Cardiovascular Disease ..... 73
3.9.1. Homocysteine 74
3.9.2. Left Ventricular Hypertrophy 76
3.9.3. Coagulation Factors 76
3.9.4. Renal Impairment 77
Contents ix
3.10. Unresolved Issues 78
References 79
Chapter 4
Effect of Infection on Lipoproteins and the Coagulation System
4.1. Introduction 91
4.2. Lipoprotein and Atherosclerosis 91
4.2.1. Acute Phase Response 92
4.2.2. Alterations of Triglyceride and VLDL Metabolism 94
4.2.3. Cholesterol and LDL Alterations 95
4.2.4. Alteration of HDL Metabolism 96
4.3. Coagulation and Atherosclerosis 98
4.3.1. The Role of Plaque Rupture 99
4.3.2. Pathophysiology of Thrombus
Formation on Atheroma 101
4.3.3. Infection and the Coagulation System 103
4.3.4. Links between Inflammation and Coagulation 104
4.3.5. Links between Inflammation, Thrombosis, and
Atherosclerosis 106
References 107
Section II
Emerging Relationships of Infections and the Cardiovascular System
Chapter 5
Chlamydia pneumoniae and the Cardiovascular System
5.1. Microbiology of Chlamydia pneumoniae 121
5.2. Chlamydia Antigens 124
5.3. Epidemiology of Chlamydia pneumoniae Infections 124
5.4. Diagnosis of Chlamydia pneumoniae Infections 125
5.4.1. Serological Testing 125
5.4.2. Culture 126
5.4.3. Polymerase Chain Reaction (PCR) 129
5.4.4. Immunohistochemistry 129
5.5. Association of C. pneumoniae Infection and
Vascular Disease 130
x Contents
5.5.1. Epidemiological Association 131
5.5.2. Pathological Evidence of Association 139
5.5.3. Culture of C. pneumoniae from Plaques 143
5.6. Evidence of Causality 144
5.6.1. Biological Mechanisms 144
5.6.2. Animal Models 146
5.6.3. Effect of Antimicrobials on Atherosclerosis in
Animal Models 150
5.6.4. Clinical Trails 151
5.7. Future Directions 153
Addendum 155
References 156
Chapter 6
Periodontal Disease and the Cardiovascular System
6.1. Introduction 179
6.2. Periodontal Disease 179
6.2.1. Microbial Etiology 180
6.2.2. Pathobiology of Periodontal Disease 181
6.2.3. Risk Factors for Periodontal Disease 182
6.3. Periodontal Disease and Cardiovascular Disease and
Atherosclerosis 183
6.3.1. Epidemiological Evidence 183
6.3.2. Pathological Evidence 189
6.4. Biological Mechanisms 189
6.4.1. Animal Models 192
6.4.2. Clinical Trials 193
6.5. Future Directions 194
References 195
Chapter 7
Cytomegalovirus and Herpes Simplex Virus in Cardiovascular Disease
7.1. Introduction 201
7.2. Microbiology 201
7.2.1. Cytomegalovirus 201
7.2.2. Herpes Simplex Virus 203
7.2.3. Epidemiology of Cytomegalovirus and
Herpes Simplex Virus 204
Contents xi
7.3. Association of Cytomegalovirus and Cardiovascular Disease 204
7.3.1. Epidemiological Association of Cytomegalovirus in
Native Coronary Heart Disease 205
7.3.2. Epidemiological Association of Cytomegalovirus in
Cardiac Transplant 210
7.3.3. Epidemiological Association of Herpes Simplex
Virus and Atherosclerotic Disease 210
7.4. Pathological Studies 210
7.5. Biological Mechanisms 220
7.5.1. Effect on Cholesterol and Lipoproteins 221
7.5.2. Viral Infection and the Coagulation Cascade 222
7.6. Animal Models 224
7.6.1. Animal Models of Allograft Arteriosclerosis 224
7.7. Clinical Trials in Transplant Atherosclerosis 225
7.8. Conclusion and Future Directions 226
References 226
Chapter 8
Miscellaneous Infections and Atherosclerosis:
Cardiovascular and Cerebrovascular Disease
8.1. Introduction 239
8.2. Helicobacter pylori and the Cardiovascular System 239
8.2.1. Microbiology and Epidemiology 239
8.2.2. Pathogenicity of Helicobacter pylori 240
8.2.3. Diagnosis of Helicobacter pylori Infection 241
8.3. Epidemiological Association ofHelicobacter pylori and
Cardiovascular Disease 241
8.3.1. Pathological Association of Helicobacter pylori and
Atherosclerosis 242
8.3.2. Biological Mechanisms for Helicobacter pylori 245
8.3.3. Animal Model fox Helicobacter pylori 247
8.3.4. Clinical Trials in Helicobacter pylori Infection and
Cardiovascular Disease 247
8.4. Viruses (other than Herpes Viruses) Associated with
Atherosclerotic Cardiovascular Disease 248
8.4.1. Coxsackie Virus 248
8.4.2. Influenza Virus 248
8.4.3. Hepatitis A Virus 249
8.4.4. Human Immunodeficiency Virus (HTV) 250
I
xii Contents
8.5. Mycoplasmapneumoniae and Cardiovascular/
Cerebrovascular Disease 251
8.6. Pathogen Burden and Atherosclerotic Vascular Disease 251
8.6.1. Pathological Evidence of Multiple Organisms in
Atheroma 253
8.6.2. Biological Mechanisms and Animal Model for
Multiple Pathogens in Atherosclerosis 255
8.7. Conclusion and Future Directions 255
References 256
Index 267
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| language | English |
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| physical | XII, 270 S. Ill., graph. Darst. |
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| series2 | Emerging infectious diseases of the 21st century |
| spelling | Infections and the cardiovascular system new perspectives ed. by I. W. Fong New York [u.a.] Kluwer Academic/Plenum 2003 XII, 270 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Emerging infectious diseases of the 21st century Includes bibliographical references and index Cardiovascular Diseases etiology Cardiovascular system Infections Communicable Diseases etiology Kardiovaskuläres System (DE-588)4024665-6 gnd rswk-swf Infektion (DE-588)4161650-9 gnd rswk-swf Kardiovaskuläres System (DE-588)4024665-6 s Infektion (DE-588)4161650-9 s DE-604 Fong, Ignatius W. Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009952677&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Infections and the cardiovascular system new perspectives Cardiovascular Diseases etiology Cardiovascular system Infections Communicable Diseases etiology Kardiovaskuläres System (DE-588)4024665-6 gnd Infektion (DE-588)4161650-9 gnd |
| subject_GND | (DE-588)4024665-6 (DE-588)4161650-9 |
| title | Infections and the cardiovascular system new perspectives |
| title_auth | Infections and the cardiovascular system new perspectives |
| title_exact_search | Infections and the cardiovascular system new perspectives |
| title_full | Infections and the cardiovascular system new perspectives ed. by I. W. Fong |
| title_fullStr | Infections and the cardiovascular system new perspectives ed. by I. W. Fong |
| title_full_unstemmed | Infections and the cardiovascular system new perspectives ed. by I. W. Fong |
| title_short | Infections and the cardiovascular system |
| title_sort | infections and the cardiovascular system new perspectives |
| title_sub | new perspectives |
| topic | Cardiovascular Diseases etiology Cardiovascular system Infections Communicable Diseases etiology Kardiovaskuläres System (DE-588)4024665-6 gnd Infektion (DE-588)4161650-9 gnd |
| topic_facet | Cardiovascular Diseases etiology Cardiovascular system Infections Communicable Diseases etiology Kardiovaskuläres System Infektion |
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