Transgenic mouse: methods and protocols
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Totowa, NJ
Humana Press
2003
|
| Series: | Methods in molecular biology
209 |
| Subjects: | |
| Online Access: | Table of contents Inhaltsverzeichnis |
| Item Description: | Includes bibliographical references and index |
| Physical Description: | xiii, 3741 p. ill. (some col.) : 24 cm |
| ISBN: | 0896039153 |
Staff View
MARC
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| 245 | 1 | 0 | |a Transgenic mouse |b methods and protocols |c edited by Marten H. Hofker, Jan van Deursen |
| 264 | 1 | |a Totowa, NJ |b Humana Press |c 2003 | |
| 300 | |a xiii, 3741 p. |b ill. (some col.) : 24 cm | ||
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| 650 | 4 | |a Wissenschaftliches Arbeiten | |
| 650 | 4 | |a Mice, Transgenic |v Laboratory Manuals | |
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Record in the Search Index
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|---|---|
| adam_text | Contents
Preface v
Contributors ix
Color Plates xiii
1 Introduction: The Use of Transgenic Mice in Biomedical Research
Marten H. Hofker 1
2 Genetic Modification of the Mouse:
General Technology; Pronuclear and Blastocyst Injection
J. Willem Voncken 9
3 In Vitro Fertilization/Cryopreservation
Susan Marschall and Martin Hrabe de Angelis 35
4 Transgene Design
J. Willem Voncken 51
5 Generating Conditional Mouse Mutants
via Tetracycline Controlled Gene Expression
Kai Schonig and Hermann Bujard 69
6 Manipulating Large Insert Clones for Transgenesis
Sally P. A. McCormick, Catherine Y. Y. Liu, Stephen G. Young,
and Lars B. Nielsen 105
7 Reporter Molecules in Genetically Engineered Mice
Thomas L. Saunders 125
8 Gene Targeting in Mouse Embryonic Stem Cells
Jan van Deursen 145
9 Conditional Knockout Mice
Ralf Kiihn and Frieder Schwenk 159
10 Knockin Approaches
Anton J. M. Roebroek, Xiaosheng Wu, and Richard J. Bram 187
11 Aggregation of Embryos and Embryonic Stem Cells
Ronald Maatman, Marina Gertsenstein, Emile de Meijer,
Andras Nagy, and Kristina Vintersten 201
12 Andenovirus Mediated Gene Transfer
Ko Willems van Dijk, Kyriakos E. Kypreos,
Christine d Oliveira, and Frits J. Fallaux 231
wii
v/77 Contents
13 Random ENU Mutagenesis
Dian Soewarto, Veronique Blanquet,
and Martin HrabS de Angelis 249
14 Autopsy and Histologic Analysis of the Transgenic Mouse
Marion J. J. Gijbels and Menno P. J. de Winther 267
15 Bone Marrow Transplantations to Study Gene Function
in Hematopoietic Cells
Menno P. J. de Winther and Peter Heeringa 281
16 Quantification of Atherosclerosis in Mice
Alan Daughterly and Stewart C. Whitman 293
17 Genetically Modified Mice in Cancer Research
David A. Largaespada 311
18 Neuropathobiology in Transgenic Mice:
The Case of Alzheimer s Disease
Jo Van Dorpe, Kurt Spittaels, Chris Van den Haute,
Use Dewachter, Dieder Moechars, Hugo Geerts,
and Fred Van Leuven 333
Index 363
|
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| isbn | 0896039153 |
| language | English |
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| physical | xiii, 3741 p. ill. (some col.) : 24 cm |
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| spelling | Transgenic mouse methods and protocols edited by Marten H. Hofker, Jan van Deursen Totowa, NJ Humana Press 2003 xiii, 3741 p. ill. (some col.) : 24 cm txt rdacontent n rdamedia nc rdacarrier Methods in molecular biology 209 Includes bibliographical references and index Muizen gtt Souris transgéniques - Manuels de laboratoire Transgene organismen gtt Wetenschappelijke technieken gtt Wissenschaftliches Arbeiten Mice, Transgenic Laboratory Manuals Transgenic mice Laboratory manuals Transgene Tiere (DE-588)4279021-9 gnd rswk-swf Maus (DE-588)4169148-9 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Maus (DE-588)4169148-9 s Transgene Tiere (DE-588)4279021-9 s DE-604 Hofker, Marten H. Sonstige oth Deursen, Johannes Martinus Adrianus van 1963- Sonstige (DE-588)172730937 oth Methods in molecular biology 209 (DE-604)BV035362695 209 http://www.loc.gov/catdir/toc/fy035/2002068581.html Table of contents HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009890496&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Transgenic mouse methods and protocols Methods in molecular biology Muizen gtt Souris transgéniques - Manuels de laboratoire Transgene organismen gtt Wetenschappelijke technieken gtt Wissenschaftliches Arbeiten Mice, Transgenic Laboratory Manuals Transgenic mice Laboratory manuals Transgene Tiere (DE-588)4279021-9 gnd Maus (DE-588)4169148-9 gnd |
| subject_GND | (DE-588)4279021-9 (DE-588)4169148-9 (DE-588)4143413-4 |
| title | Transgenic mouse methods and protocols |
| title_auth | Transgenic mouse methods and protocols |
| title_exact_search | Transgenic mouse methods and protocols |
| title_full | Transgenic mouse methods and protocols edited by Marten H. Hofker, Jan van Deursen |
| title_fullStr | Transgenic mouse methods and protocols edited by Marten H. Hofker, Jan van Deursen |
| title_full_unstemmed | Transgenic mouse methods and protocols edited by Marten H. Hofker, Jan van Deursen |
| title_short | Transgenic mouse |
| title_sort | transgenic mouse methods and protocols |
| title_sub | methods and protocols |
| topic | Muizen gtt Souris transgéniques - Manuels de laboratoire Transgene organismen gtt Wetenschappelijke technieken gtt Wissenschaftliches Arbeiten Mice, Transgenic Laboratory Manuals Transgenic mice Laboratory manuals Transgene Tiere (DE-588)4279021-9 gnd Maus (DE-588)4169148-9 gnd |
| topic_facet | Muizen Souris transgéniques - Manuels de laboratoire Transgene organismen Wetenschappelijke technieken Wissenschaftliches Arbeiten Mice, Transgenic Laboratory Manuals Transgenic mice Laboratory manuals Transgene Tiere Maus Aufsatzsammlung |
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| volume_link | (DE-604)BV035362695 |
| work_keys_str_mv | AT hofkermartenh transgenicmousemethodsandprotocols AT deursenjohannesmartinusadrianusvan transgenicmousemethodsandprotocols |