Biological role of inorganic pyrophosphate:
Saved in:
| Main Author: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Boston [u.a.]
Kluwer Acad. Publ.
2001
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | VIII, 250 S. graph. Darst. |
| ISBN: | 079237441X |
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| 650 | 7 | |a Biologisches System |2 swd | |
| 650 | 7 | |a Diphosphate |2 swd | |
| 650 | 7 | |a Hydrolyse |2 swd | |
| 650 | 4 | |a Diphosphates |x metabolism | |
| 650 | 4 | |a Pyrophosphates |x Metabolism | |
| 650 | 4 | |a Pyrophosphates |x Physiological effect | |
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Record in the Search Index
| _version_ | 1804128830522130432 |
|---|---|
| adam_text | BIOLOGICAL ROLE OF
INORGANIC PYROPHOSPHATE
by
Jukka K Heinonen
University of Turku, Finland
KLUWER ACADEMIC PUBLISHERS
Boston / Dordrecht / London
CONTENTS
PREFACE vii
ACKNOWLEDGEMENTS «
ABBREVIATIONS : xi
1 BIOLOGICAL PRODUCTION OF PPi 1
1 1 PPi producing reactions 1
111 Number and types of the reactions 1
112 Why is PPj produced in biosynthetic reactions 10
113 PP; synthesis using chemical gradients 1 4
1 2 Rate and amount of PPj production in biochemical reactions 23
2 DETERMINATION OF PPS CONCENTRATION IN LIVING
SYSTEMS 29
2 1 Sampling and extraction 29
2 2 Assays 34
221 Radiochemical determinations 34
222 Colorimetric PPj assays 36
223 Enzymatic methods 37
224 Physical methods 41
225 Calculation of PPj concentration from the equilibrium constant of a
biochemical reaction 42
2 3 Conclusions 43
3 PPjCONCENTRATION IN BIOLOGICAL MATERIAL 45
3 1 Bacteria , 45
3 2 Lower eukaryotes 48
3 3 Plants 5 3
3 4 Animals 6 0
3 5 Humans
k
351 Blood 6 5
352 Urine 69
353 Synovial fluid 7 3
354 Saliva 73
355 Bone, tooth, and cartilage : 74
356 Cultured human cells 74
4 PPi AS A BIOCHEMICAL ENERGY SOURCE 77
4 1 General considerations 77
4 2 Bacteria 79
4 3 Protists 89
4 4 Plants 93
441 PPj-dependent enzymes in plants 95
VI
442 Role of UDPG-pyrophosphorylase 101
443 Role of H*-translocating PPase 103
444 Role of PPj -dependent phosphofructokinase 105
445 Conclusions I l l
4 5 Animals 112
4 6 Other eukaryotes 115
4 7 PPj as an energy source of primitive life 117
5 REGULATORY ROLES OF PPj 123
5 1 PPi as a regulator of enzyme activity 123
511 Binding of metal ions 123
512 Product inhibition 125
513 Other cases 134
514 PPj as an activator of enzymes 141
515 PPj and adenine nucleotide translocase 144
5 2 Regulation of nucleic acid and protein synthesis 148
521 Fidelity of the syntheses 148
522 PPj in proofreading 149
5 3 PPj and calcification 159
531 Bone formation and resorption 159
532 Tooth 166
533 Urolithiasis 168
534 Pathologic calcification of soft tissues 171
5 4 Effect of extracellular PP; 173
541 PPj and cell proliferation 173
542 CPPD crystal deposition disease 177
5 5 PPi and iron metabolism 183
INDEX 189
REFERENCES 197
|
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| id | DE-604.BV013977862 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:55:29Z |
| institution | BVB |
| isbn | 079237441X |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-009568108 |
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| physical | VIII, 250 S. graph. Darst. |
| publishDate | 2001 |
| publishDateSearch | 2001 |
| publishDateSort | 2001 |
| publisher | Kluwer Acad. Publ. |
| record_format | marc |
| spelling | Heinonen, Jukka K. Verfasser aut Biological role of inorganic pyrophosphate by Jukka K. Heinonen Boston [u.a.] Kluwer Acad. Publ. 2001 VIII, 250 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Biologisches System swd Diphosphate swd Hydrolyse swd Diphosphates metabolism Pyrophosphates Metabolism Pyrophosphates Physiological effect HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009568108&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Heinonen, Jukka K. Biological role of inorganic pyrophosphate Biologisches System swd Diphosphate swd Hydrolyse swd Diphosphates metabolism Pyrophosphates Metabolism Pyrophosphates Physiological effect |
| title | Biological role of inorganic pyrophosphate |
| title_auth | Biological role of inorganic pyrophosphate |
| title_exact_search | Biological role of inorganic pyrophosphate |
| title_full | Biological role of inorganic pyrophosphate by Jukka K. Heinonen |
| title_fullStr | Biological role of inorganic pyrophosphate by Jukka K. Heinonen |
| title_full_unstemmed | Biological role of inorganic pyrophosphate by Jukka K. Heinonen |
| title_short | Biological role of inorganic pyrophosphate |
| title_sort | biological role of inorganic pyrophosphate |
| topic | Biologisches System swd Diphosphate swd Hydrolyse swd Diphosphates metabolism Pyrophosphates Metabolism Pyrophosphates Physiological effect |
| topic_facet | Biologisches System Diphosphate Hydrolyse Diphosphates metabolism Pyrophosphates Metabolism Pyrophosphates Physiological effect |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009568108&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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