Role of potassium in preventive cardiovascular medicine:
Saved in:
| Main Author: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Boston [u.a.]
Kluwer
2001
|
| Series: | Basic science for the cardiologist
8 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XV, 219 S. graph. Darst. |
| ISBN: | 0792373766 |
Staff View
MARC
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| 245 | 1 | 0 | |a Role of potassium in preventive cardiovascular medicine |c by David B. Young |
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| 300 | |a XV, 219 S. |b graph. Darst. | ||
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| 490 | 1 | |a Basic science for the cardiologist |v 8 | |
| 650 | 4 | |a Cardiovascular Diseases |x prevention & control | |
| 650 | 4 | |a Cardiovascular Physiological Phenomena | |
| 650 | 4 | |a Cardiovascular system |x Diseases |x Prevention | |
| 650 | 4 | |a Cardiovascular system |x Pathophysiology | |
| 650 | 4 | |a Potassium |x Physiological effect | |
| 650 | 4 | |a Potassium |x physiology | |
| 650 | 4 | |a Potassium |x therapeutic use | |
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Record in the Search Index
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|---|---|
| adam_text | FOREWORD xiii
John H. Laragh, Jr., M.D.
1 INTRODUCTION 1
SECTION I: POTASSIUM REGULATION
2 PHYSIOLOGY OF POTASSIUM REGULATION 9
Potassium Transport Along the Nephron 10
Regulation of Potassium Distribution 14
Hormonal and Non Hormonal Factors that May
Affect Potassium Excretion and Distribution 17
Long Term Regulation of Potassium: Importance
of Aldosterone and Extracellular Potassium
Concentration 25
Systems Analyses of Potassium Regulation 31
Summary 41
3 INTERACTIONS BETWEEN CARDIOVASCULAR
PHARMACOTHERAPEUTICS AND
POTASSIUM REGULATION 43
Diuretics 44
Angiotensin Converting Enzyme Inhibitors and
Angiotensin II Receptor Antagonists 47
Mineralocorticoid Antagonists 48
Beta Adrenergic Receptor Antagonists 50
Summary 50
4 POTASSIUM DEPLETION AND HYPOKALEMIA 51
Symptoms 52
Etiology 55
Diagnosis 62
Treatment 63
Summary 67
SECTION II: CARDIOVASCULAR
RESPONSES TO CHANGES IN POTASSIUM
5 VASCULAR CELL RESPONSES TO CHANGES IN
POTASSIUM CONCENTRATION 71
Cellular Basis of Atherosclerotic Lesion Formation 72
Cellular Basis of Restenosis Lesion Formation 75
Reduction in Platelet Sensitivity in Response to
Increases in Potassium Concentration 75
Oxygen Free Radical Formation is Inhibited by
Elevation of Potassium Concentration 77
Inhibition of Vascular Smooth Muscle Proliferation
Cell by Elevation of Potassium Concentration 78
Inhibition of Vascular Smooth Muscle Migration
by Elevation of Potassium Concentration 82
Summary: Proposed Mechanisms of Cardiovascular
Protective Effect of Dietary Potassium 86
6 INHIBITION OF THROMBOSIS AND STROKE BY
ELEVATION OF POTASSIUM 87
Inhibition of Experimental Coronary and Carotid
Artery Thrombosis by Elevation of Potassium
Concentration 88
page viii
Protection Against Stroke in the Stroke Prone
Rat Model by High Dietary Potassium Intake 91
Evidence from Population Based Studies of Protection
Against Stroke by High Dietary
Potassium Intake 93
Summary 98
7 INHIBITION BY POTASSIUM OF
ARTERIOSCLEROSIS AND ATHEROSCLEROTIC
LESION FORMATION 101
Etiology of Lesion Formation 102
Potential Mechanisms of Protection against Lesion
Development by Elevation
of Potassium Concentration 102
Inhibition by Dietary Potassium of Coronary
Arteriosclerotic Lesion Formation
in a Rabbit Model 103
Evidence from Population Based Studies of
Protection by Potassium against Development
of Arteriosclerotic Disease 105
Summary 108
8 NEOINTIMAL PROLIFERATION AND
RESTENOSIS FOLLOWING ANGIOPLASTY ARE
INHIBITED BY DIETARY POTASSIUM
SUPPLEMENTATION IN EXPERIMENTAL MODELS 111
Etiology of Restenosis 111
Inhibition of Neointimal Lesion Formation Following
Angioplasty in Animal Models by Elevation of
Dietary Potassium Intake 113
Summary 122
page ix
9 EVIDENCE OF AN INVERSE RELATIONSHIP
BETWEEN DIETARY POTASSIUM INTAKE AND BLOOD
PRESSURE 123
Blood Pressure Regulation and the
Etiology of Hypertension 124
Alterations in Blood Pressure Control Functions
of the Kidney Associated with Changes in
Potassium Intake and Plasma Potassium
Concentration 127
Reduction in Blood Pressure by Elevation of
Potassium Intake in Experimental Hypertension 134
Reduction in Blood Pressure in Hypertensive Patients
by Potassium Supplementation 135
Blood Pressure Reduction by Elevation of Potassium
Intake and Other Dietary
Modifications the DASH Trial 142
Epidemiological Evidence that High Dietary Potassium
Intake Protects Against Hypertension 147
Summary 154
10 ARRHYTHMOGENIC SIGNIFICANCE
OF HYPOKALEMIA 155
Potassium s Impact on Electrophysiological Properties
of Myocardial Cells 155
Electrocardiographic Alterations with Changes
in Potassium Concentration 159
Clinical Data Relating Hypokalemia to Arrhythmias 159
Summary 167
11 MODERATE POTASSIUM DEPLETION IMPAIRS
CARDIAC MECHANICAL FUNCTION 169
Chronic Hypokalemia and Left Ventricular
Function in Dogs 170
Cardiac Function Responses to Moderate Potassium
Depletion in Normal Volunteers 179
pagex
Summary 186
12 CONCLUSION 189
Summary 190
Recommendations 193
Conclusions 98
REFERENCES 201
INDEX 215
page xi
|
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| dewey-sort | 3616.1 15 |
| dewey-tens | 610 - Medicine and health |
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| id | DE-604.BV013925724 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:54:32Z |
| institution | BVB |
| isbn | 0792373766 |
| language | English |
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| physical | XV, 219 S. graph. Darst. |
| publishDate | 2001 |
| publishDateSearch | 2001 |
| publishDateSort | 2001 |
| publisher | Kluwer |
| record_format | marc |
| series | Basic science for the cardiologist |
| series2 | Basic science for the cardiologist |
| spelling | Young, David B. Verfasser aut Role of potassium in preventive cardiovascular medicine by David B. Young Boston [u.a.] Kluwer 2001 XV, 219 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Basic science for the cardiologist 8 Cardiovascular Diseases prevention & control Cardiovascular Physiological Phenomena Cardiovascular system Diseases Prevention Cardiovascular system Pathophysiology Potassium Physiological effect Potassium physiology Potassium therapeutic use Kardiovaskuläre Krankheit (DE-588)4024666-8 gnd rswk-swf Kalium (DE-588)4139553-0 gnd rswk-swf Kardiovaskuläre Krankheit (DE-588)4024666-8 s Kalium (DE-588)4139553-0 s DE-604 Basic science for the cardiologist 8 (DE-604)BV012774326 8 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009529545&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Young, David B. Role of potassium in preventive cardiovascular medicine Basic science for the cardiologist Cardiovascular Diseases prevention & control Cardiovascular Physiological Phenomena Cardiovascular system Diseases Prevention Cardiovascular system Pathophysiology Potassium Physiological effect Potassium physiology Potassium therapeutic use Kardiovaskuläre Krankheit (DE-588)4024666-8 gnd Kalium (DE-588)4139553-0 gnd |
| subject_GND | (DE-588)4024666-8 (DE-588)4139553-0 |
| title | Role of potassium in preventive cardiovascular medicine |
| title_auth | Role of potassium in preventive cardiovascular medicine |
| title_exact_search | Role of potassium in preventive cardiovascular medicine |
| title_full | Role of potassium in preventive cardiovascular medicine by David B. Young |
| title_fullStr | Role of potassium in preventive cardiovascular medicine by David B. Young |
| title_full_unstemmed | Role of potassium in preventive cardiovascular medicine by David B. Young |
| title_short | Role of potassium in preventive cardiovascular medicine |
| title_sort | role of potassium in preventive cardiovascular medicine |
| topic | Cardiovascular Diseases prevention & control Cardiovascular Physiological Phenomena Cardiovascular system Diseases Prevention Cardiovascular system Pathophysiology Potassium Physiological effect Potassium physiology Potassium therapeutic use Kardiovaskuläre Krankheit (DE-588)4024666-8 gnd Kalium (DE-588)4139553-0 gnd |
| topic_facet | Cardiovascular Diseases prevention & control Cardiovascular Physiological Phenomena Cardiovascular system Diseases Prevention Cardiovascular system Pathophysiology Potassium Physiological effect Potassium physiology Potassium therapeutic use Kardiovaskuläre Krankheit Kalium |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009529545&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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