How did Listeria monocytogenes become pathogenic?:
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
2001
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Zsfassung in dt. Sprache. - Würzburg, Univ., Diss., 2001 |
| Beschreibung: | VI, 117 S. Ill., graph. Darst. |
Internformat
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| 300 | |a VI, 117 S. |b Ill., graph. Darst. | ||
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Datensatz im Suchindex
| _version_ | 1812460674618490880 |
|---|---|
| adam_text |
IV
CONTENTS
ACKNOWLEDGEMENTS VI
ABSTRACT 3
ZUSAMMENFASSUNG
5
CHAPTER 1 INTRODUCTION 7
GENES ATTRIBUTED TO THE VIRULENCE PHENOTYPE 8
THE VIRULENCE GENE CLUSTER GENES 9
THE INTEMALINS 11
OTHER VIRULENCE ASSOCIATED FUNCTIONS 13
GENETIC DIVERSITY AND EXCHANGE IN
LISTERIA SPP. 15
AIMS 16
CHAPTER 2 EVOLUTION OF THE GENUS
LISTERIA 19
SOLVING THE PHYLOGENY OF GENUS
LISTERIA 20
RESULTS: VIRULENCE GENE CLUSTER
LOCI OF LISTERIA SPP. 22
VARIOUS INTEMALIN
LOCI OF LISTERIA SPP. 29
PHYLOGENY OF GENUS
LISTERIA 31
DISCUSSION: EVOLUTION OF THE VIRULENCE GENE CLUSTER 38
EVOLUTION OF THE INTEMALIN-LIKE PROTEINS 41
EVOLUTION OF
LISTERIAE AS PATHOGENS 43
CHAPTER 3 TOWARDS RECONSTITUTING A PATHOGENIC
LISTERIA ' 45
RECONSTITUTING THE VIRULENCE GENE CLUSER IN
L. INNOCUA 46
RESULTS: CLONING THE ENTIRE 12KB FRAGMENT 47
QONING THE VIRULENCE GENE CLUSTER IN 2 PARTS 51
CLONING THE VIRULENCE GENE CLUSTER IN 3 PARTS 52
FINAL STRATEGY: CHROMOSOMAL INTEGRATION INTO
L. INNOCUA 52
AND PKP1 REQUIRED MODIFICATION OF PEN03 AND PEN04
CHROMOSOMAL INTEGRATION OF PEN08 CARRYING
PRFA, PLCA, HLY 55
INTO
L. INNOCUA AND PKP1
DISCUSSION 57
POTENTIAL USES 58
BIBLIOGRAFISCHE INFORMATIONEN
HTTP://D-NB.INFO/963111922
V
CHAPTER 4 THE GENOME OF
L. MONOCYTOGENES
INTRODUCTION
RESULTS: GENERAL FINDINGS
SIGMA FACTOR SEARCH
STATIONARY PHASE GENES
DISCUSSIONS: GENERAL FINDINGS
LISTERIA
SIGMA FACTORS
LISTERIA
STATIONARY PHASE GENES
SUMMARY
61
62
63
64
67
77
78
79
81
CHAPTER 5
A.
B.
C.
D.
METHODS
CHAPTER 2: EVOLUTION OF GENUS
LISTERIA
BACTERIAL STRAINS
MEDIA ~
DNA EXTRACTION METHODS
AMPLIFICATION OF DNA FRAGMENTS FROM CHROMOSOMAL DNA
CLONING OF THE PCR PRODUCTS
DNA SEQUENCING
COMPUTER ANALYSES
ANNOTATION
PHYLOGENETIC ANALYSES
CHAPTER 3: TOWARDS RECONSTITUTING A PATHOGENIC
LISTERIA
BACTERIAL STRAINS AND PLASMIDS
MEDIA
SMALL SCALE DNA ISOLATION
SUMMARY OF PRIMERS, CONDITIONS FOR CLONING, INTEGRATION
CLONING PROCEDURES
TRANSFORMATION OF
LISTERIA
CHAPTER 4: THE GENOME OF
L. MONOCYTOGENES
STANDARDIZED PROTOCOLS DISTRIBUTED DURING GENOME PROJECT
LIST OF INTERNET SITES USED FOR ANNOTATIONS
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86
86
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87
89
89
90
90
91
94
95
96
96
99
LITERATURE CITED
LIST OF ABBREVIATIONS
LISTERIA
CONSORTIUM PARTICIPANTS
LEBENSLAUF
PUBLICATIONS
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| indexdate | 2024-10-09T18:06:33Z |
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| language | English |
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| physical | VI, 117 S. Ill., graph. Darst. |
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| spelling | Ng, Eva Yee Wah 1963- Verfasser (DE-588)123348498 aut How did Listeria monocytogenes become pathogenic? von Eva Yee Wah Ng 2001 VI, 117 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Zsfassung in dt. Sprache. - Würzburg, Univ., Diss., 2001 Molekulargenetik (DE-588)4039987-4 gnd rswk-swf Listeria monocytogenes (DE-588)4203141-2 gnd rswk-swf Evolution (DE-588)4071050-6 gnd rswk-swf Virulenz (DE-588)4129834-2 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Listeria monocytogenes (DE-588)4203141-2 s Virulenz (DE-588)4129834-2 s Evolution (DE-588)4071050-6 s Molekulargenetik (DE-588)4039987-4 s DE-604 DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009434331&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Ng, Eva Yee Wah 1963- How did Listeria monocytogenes become pathogenic? Molekulargenetik (DE-588)4039987-4 gnd Listeria monocytogenes (DE-588)4203141-2 gnd Evolution (DE-588)4071050-6 gnd Virulenz (DE-588)4129834-2 gnd |
| subject_GND | (DE-588)4039987-4 (DE-588)4203141-2 (DE-588)4071050-6 (DE-588)4129834-2 (DE-588)4113937-9 |
| title | How did Listeria monocytogenes become pathogenic? |
| title_auth | How did Listeria monocytogenes become pathogenic? |
| title_exact_search | How did Listeria monocytogenes become pathogenic? |
| title_full | How did Listeria monocytogenes become pathogenic? von Eva Yee Wah Ng |
| title_fullStr | How did Listeria monocytogenes become pathogenic? von Eva Yee Wah Ng |
| title_full_unstemmed | How did Listeria monocytogenes become pathogenic? von Eva Yee Wah Ng |
| title_short | How did Listeria monocytogenes become pathogenic? |
| title_sort | how did listeria monocytogenes become pathogenic |
| topic | Molekulargenetik (DE-588)4039987-4 gnd Listeria monocytogenes (DE-588)4203141-2 gnd Evolution (DE-588)4071050-6 gnd Virulenz (DE-588)4129834-2 gnd |
| topic_facet | Molekulargenetik Listeria monocytogenes Evolution Virulenz Hochschulschrift |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009434331&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT ngevayeewah howdidlisteriamonocytogenesbecomepathogenic |