Neuroscience: exploring the brain
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Baltimore, Md. [u.a.]
Lippincott Williams & Wilkins
2001
|
| Edition: | 2. ed. |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XXIX, 855 S. Ill., graph. Darst. |
| ISBN: | 0683305964 0781732557 |
Staff View
MARC
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| 100 | 1 | |a Bear, Mark F. |e Verfasser |0 (DE-588)14280858X |4 aut | |
| 245 | 1 | 0 | |a Neuroscience |b exploring the brain |c Mark F. Bear ; Barry W. Connors ; Michael A. Paradiso |
| 250 | |a 2. ed. | ||
| 264 | 1 | |a Baltimore, Md. [u.a.] |b Lippincott Williams & Wilkins |c 2001 | |
| 300 | |a XXIX, 855 S. |b Ill., graph. Darst. | ||
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Record in the Search Index
| _version_ | 1804128553024880640 |
|---|---|
| adam_text | Contents in Brief
1 The Organization of the Nervous System 1
Unit I NEURAL SIGNALING
2 Electrical Signals of Nerve Cells 43
3 Voltage-Dependent Membrane Permeability 57
4 Channels and Transporters 77
5 Synaptic Transmission 99
6 Neurotransmitters 11 7
7 Neurotransmitter Receptors and Their Effects 141
8 Intracellular Signal Transduction 165
UnitII SENSATION AND SENSORY PROCESSING
9 The Somatic Sensory System 189
10 Pain 209
11 Vision: The Eye 223
12 Central Visual Pathways 251
1 3 The Auditory System 275
14 The Vestibular System 297
15 The Chemical Senses 31 7
Unit III MOVEMENT AND ITS CENTRAL CONTROL
16 Lower Motor Neuron Circuits and Motor Control 347
17 Upper Motor Neuron Control of the Brainstem and Spinal Cord 369
18 Modulation of Movement by the Basal Ganglia 391
19 Modulation of Movement by the Cerebellum 409
20 Eye Movements and Sensory Motor Integration 427
21 The Visceral Motor System 443
Unit IV THE CHANGING BRAIN
22 Early Brain Development 471
23 Construction of Neural Circuits 493
24 Modification of Brain Circuits as a Result of Experience 519
25 Plasticity of Mature Synapses and Circuits 535
Unit V COMPLEX BRAIN FUNCTIONS
26 The Association Cortices 565
27 Language and Lateralization 587
28 Sleep and Wakefulness 603
29 Emotions 625
30 Sex, Sexuality, and the Brain 645
31 Human Memory 665
Contents
Preface xvi
Acknowdgments xvii
Supplements to Accompany NEUROSCIENC
1. The Organization of the
Nervous System 1
Overview 1
The Cellular Components of the Nervous System 1
Nerve Cells 3
Neuroglial Cells 6
Neural Circuits 8
Neural Systems 10
Some Anatomical Terminology 12
The Subdivisions of the Central Nervous System 13
BOX A The Brainstem and Its Importance in
Clinical Neuroanatomy 15
The External Anatomy of the Spinal Cord 18
The Internal Anatomy of the Spinal Cord 19
The External Anatomy of the Brain: Some General
Points 20
Unit I ^^B NEURAL SIGNAI
2. Electrical Signals of Nerve Cells 43
Overview 43
Electrical Potentials Across Nerve Cell
Membranes 43
How Ionic Movements Produce Electrical Signals 45
The Forces that Create Membrane Potentials 47
Electrochemical Equilibrium in an Environment
with More Than One Permeant Ion 49
The Ionic Basis of the Resting Membrane Potential
51
The Ionic Basis of Action Potentials 52
BOX A The Remarkable Giant Nerve Cells
of Squid 53
BOX B Action Potential Form and Nomenclature 55
Summary 56
f xviii
The Lateral Surface of the Brain 21
The Dorsal and Ventral Surfaces of the Brain 22
The Midline Sagittal Surface of the Brain 23
The Internal Anatomy of the Brain 25
The Internal Anatomy of the Cerebral Hemispheres
and Diencephalon 25
BOX B Anatomical Brain Imaging Techniques 26
BOX C Functional Brain Imaging: PET, SPECT,
and fMRI 28
The Ventricular System 31
The Meninges 33
BOX D Stroke 33
The Blood Supply of the Brain and Spinal Cord 35
BOX E The Blood-Brain Barrier 38
Summary 39
LING
3. Voltage-Dependent Membrane
Permeability 57
Overview 57
Ionic Currents Across Nerve Cell Membranes 57
BOX A The Voltage Clamp Method 58
Two Types of Voltage-Dependent Ionic Current 59
Two Voltage-Dependent Membrane
Conductances 61
Reconstruction of the Action Potential 64
Long-Distance Signaling by Means of Action
Potentials 65
BOX B Threshold 66
BOX C Passive Membrane Properties 68
The Refractory Period 72
Increased Conduction Velocity as a Result of
Myelination 72
BOX D Multiple Sclerosis 75
Summary 76
4. Channels and Transporters 77
Overview 77
Ion Channels Underlying Action Potentials 77
BOX A The Patch Clamp Method 78
The Diversity of Ion Channels 81
Voltage-Gated Ion Channels 82
BOX B Expression of Ion Channels in Xenopus
Oocytes 85
Ligand-Gated Ion Channels 86
Stretch- and Heat-Activated Channels 86
The Molecular Structure of Ion Channels 86
Active Transporters Create and Maintain Ion
Gradients 89
BOX C Toxins That Poison Ion Channels 90
BOX D Diseases Caused by Altered Ion Channels 92
Functional Properties of the Na+/K+ Pump 93
The Molecular Structure of the Na+/K+ Pump 95
Summary 96
5. Synaptic Transmission 99
Overview 99
Electrical Synapses 99
Chemical Synapses 101
Quantal Transmission at Neuromuscular Synapses
103
Release of Transmitters from Synaptic Vesicles 105
Local Recycling of Synaptic Vesicles 106
The Role of Calcium in Transmitter Secretion 107
BOX A Diseases That Affect the Presynaptic
Terminal 108
Molecular Mechanisms of Transmitter Secretion
111
BOX B Toxins That Affect Transmitter Release 114
Summary 115
6. Neurotransmitters 117
Overview 117
What Defines a Neurotransmitter? 117
BOX A Criteria That Define a Neurotransmitter 119
Two Major Categories of Neurotransmitters 120
Neurons Often Release More Than One Trans¬
mitter 122
Neurotransmitter Synthesis 123
Contents ix
Packaging Neurotransmitters 126
Neurotransmitter Release and Removal 126
Acetylcholine 127
Glutamate 129
GABA and Glycine 130
BOX B Excitotoxicity in Acute Neuronal Injury 130
The Biogenic Amines 131
ATP and Other Purines 135
Peptide Neurotransmitters 135
BOX C Biogenic Amine Neurotransmitters
and Psychiatric Disorders 137
BOXD Addiction 138
Summary 139
7. Neurotransmitter Receptors and Their
Effects 141
Overview 141
Neurotransmitter Receptors Alter Postsynaptic
Membrane Permeability 141
Principles Derived from Studies of the
Neuromuscular Junction 141
Excitatory and Inhibitory Postsynaptic
Potentials 147
Summation of Synaptic Potentials 149
Two Families of Postsynaptic Receptors 150
Cholinergic Receptors 151
Glutamate Receptors 153
BOX A Neurotoxins That Act on Postsynaptic
Receptors 156
BOX B Myasthenia Cravis: An Autoimmune
Disease of Neuromuscular Synapses 158
GABA and Glycine Receptors 159
Serotonin Receptors 161
Purinergic Receptors 161
Catecholamine Receptors 162
Peptide Receptors 162
Summary 162
8. Intracellular Signal Transduction 165
Overview 165
Strategies of Molecular Signaling 165
The Activation of Signaling Pathways 167
Receptor Types 168
G-Proteins and Their Molecular Targets 170
Second Messengers 172
Second Messenger Targets: Protein Kinases
and Phosphatases 175
Nuclear Signaling 178
Examples of Neuronal Signal Transduction 181
Summary 185
x Contents
Unit II ^^^S SENSATior
9. The Somatic Sensory System 189
Overview 189
Cutaneous and Subcutaneous Somatic Sensory
Receptors 189
Mechanoreceptors Specialized to Receive
Tactile Information 192
Differences in Mechanosensory Discrimination
Across the Body Surface 194
BOX A Receptive Fields and Sensory Maps
in the Cricket 195
BOX B Dynamic Aspects of Somatic Sensory
Receptive Fields 196
Mechanoreceptors Specialized for Proprioception 197
Active Tactile Exploration 199
The Major Afferent Pathway for Mechanosensory
Information: The Dorsal Column-Medial
Lemniscus System 199
BOX C Dermatomes 201
The Trigeminal Portion of the Mechanosensory
System 202
The Somatic Sensory Components of the Thalamus
203
The Somatic Sensory Cortex 204
BOX D Patterns of Organization within the Sensory
Cortices: Brain Modules 206
Higher-Order Cortical Representations 207
Summary 207
10. Pain 209
Overview 209
Nociceptors 209
The Perception of Pain 210
Hyperalgesia and Sensitization 211
Central Pain Pathways: The Spinothalamic Tract 212
The Nociceptive Components of the Thalamus
and Cortex 214
BOX A Referred Pain 215
BOX B Phantom Limbs and Phantom Pain 216
Central Regulation of Pain Perception 217
The Placebo Effect 219
The Physiological Basis of Pain Modulation 220
Summary 221
11. Vision: The Eye 223
Overview 223
Anatomy of the Eye 223
The Formation of Images on the Retina 224
BOX A Myopia and Other Refractive Errors 226
The Retina 227
4 AND SENSORY PROCESSING
——————fHHHHIil1 ll l II ili)l I11! !
Phototransduction 230
BOX B Retinitis Pigmentosa 231
Functional Specialization of the Rod and Cone
Systems 234
BOX C Macular Degeneration 236
Anatomical Distribution of Rods and Cones 237
Cones and Color Vision 239
BOX D The Importance of Context in Color
Perception 240
Retinal Circuits for Detecting Differences in
Luminance 242
BOX E The Perception of Luminance 244
Contribution of Retinal Circuits to Light
Adaptation 247
Summary 249
12. Central Visual Pathways 251
Overview 251
Central Projections of Retinal Ganglion Cells 251
BOX A The Blind Spot 254
The Retinotopic Representation of the
Visual Field 255
Visual Field Deficits 258
The Functional Organization of the Striate
Cortex 260
The Columnar Organization of the Striate
Cortex 263
BOX B Random Dot Stereograms and Related
Amusements 264
BOX C Optical Imaging of Functional Domains in
the Visual Cortex 266
Parallel Streams of Information from Retina
to Cortex 268
The Functional Organization of Extrastriate
Visual Areas 270
Summary 273
13. The Auditory System 275
Overview 275
Sound 275
The Audible Spectrum 276
A Synopsis of Auditory Function 276
BOX A Four Causes of Acquired Hearing Loss 277
The External Ear 278
The Middle Ear 279
The Inner Ear 279
Hair Cells and the Mechanoelectrical Transduction
of Sound Waves 282
BOX B The Sweet Sound of Distortion 285
Two Kinds of Hair Cells in the Cochlea 286
Tuning and Timing in the Auditory Nerve 287
How Information from the Cochlea Reaches
Targets in the Brainstem 288
Integrating Information from the Two Ears 288
Monaural Pathways from the Cochlear Nucleus
to the Lateral Lemniscus 292
Integration in the Inferior Colliculus 292
The Auditory Thalamus 293
The Auditory Cortex 294
Summary 295
14. The Vestibular System 297
Overview 297
The Vestibular Labyrinth 297
Vestibular Hair Cells 298
The Otolith Organs: The Utricle and Sacculus 300
BOX A A Primer on (Vestibular) Navigation 300
How Otolith Neurons Sense Linear Forces 302
BOX B Adaptation and Tuning of Vestibular Hair
Cells 304
The Semicircular Canals 306
How Semicircular Canal Neurons Sense
Angular Accelerations 307
BOX C Throwing Cold Water on the Vestibular
System 308
Central Vestibular Pathways: Eye, Head, and Body
Reflexes 310
BOX D Mauthner Cells in Fish 312
HMLMl ^^m M0VEIVIENT
16. Lower Motor Neuron Circuits and
Motor Control 347
Overview 347
Neural Centers Responsible for Movement 347
Motor Neuron-Muscle Relationships 349
The Motor Unit 351
The Regulation of Muscle Force 353
The Spinal Cord Circuitry Underlying
Muscle Stretch Reflexes 355
The Influence of Afferent Activity on Motor
Behavior 357
Other Afferent Feedback that Affects Motor
Performance 358
Flexion Reflex Pathways 361
Spinal Cord Circuitry and Locomotion 361
Contents xi
Vestibular Pathways to the Thalamus and Cortex
314
Summary 315
15. The Chemical Senses 317
Overview 317
The Organization of the Olfactory System 317
Olfactory Perception in Humans 319
Physiological and Behavioral Responses to
Odorants 320
The Olfactory Epithelium and Olfactory Receptor
Neurons 321
BOX A Olfaction, Pheromones, and Behavior
in the Hawk Moth 322
The Transduction of Olfactory Signals 323
Odorant Receptors and Olfactory Coding 324
The Olfactory Bulb 327
BOX B Temporal Coding of Olfactory Information
in Insects 328
Central Projections of the Olfactory Bulb 329
The Organization of the Taste System 330
Taste Perception in Humans 332
The Organization of the Peripheral Taste System 334
Idiosyncratic Responses to Various Tastants 335
Taste Receptors and the Transduction of Taste
Signals 336
Neural Coding in the Taste System 340
Central Processing of Taste Signals 340
Trigeminal Chemoreception 341
BOXC Capsaicin 342
Summary 343
AND ITS CENTRAL CONTROL
BOX A Locomotion in the Leech and the
Lamprey 362
BOX B The Autonomy of Central Pattern
Generators: Evidence from the Lobster
Stomatogastric Ganglion 364
The Lower Motor Neuron Syndrome 366
Summary 367
BOX C Amyotrophic Lateral Sclerosis 367
17. Upper Motor Neuron Control of the
Brainstem and Spinal Cord 369
Overview 369
Descending Control of Spinal Cord Circuitry:
General Information 369
xii Contents
Motor Control Centers in the Brainstem:
Upper Motor Neurons That Maintain Balance
and Posture 370
The Primary Motor Cortex: Upper Motor Neurons
That Initiate Complex Voluntary Movements 375
Functional Organization of the Primary Motor
Cortex 376
BOX A Descending Projections to Cranial Nerve
Motor Nuclei and Their Importance in Diag¬
nosing the Cause of Motor Deficits 378
BOX B What Do Motor Maps Represent? 380
BOX C Sensory Motor Talents and Cortical Space
383
The Premotor Cortex 384
Damage to Descending Motor Pathways:
The Upper Motor Neuron Syndrome 386
BOX A Muscle Tone 387
Summary 388
18. Modulation of Movement by the
Basal Ganglia 391
Overview 391
Projections to the Basal Ganglia 391
Projections from the Basal Ganglia to Other Brain
Regions 396
Evidence from Studies of Eye Movements 397
Circuits within the Basal Ganglia System 400
BOX A Huntington s Disease 400
BOX B Parkinson s Disease: An Opportunity for
Novel Therapeutic Approaches 403
BOX C Basal Ganglia Loops and Non-Motor Brain
Functions 406
Summary 407
19. Modulation of Movement by the
Cerebellum 409
Overview 409
Organization of the Cerebellum 409
Projections to the Cerebellum 412
Projections from the Cerebellum 414
Circuits within the Cerebellum 415
BOX A Prion Diseases 418
Cerebellar Circuitry and the Coordination
of Ongoing Movement 419
Consequences of Cerebellar Lesions 422
BOX B Genetic Analysis of Cerebellar Function 423
Summary 425
20. Eye Movements and Sensory Motor
Integration 427
Overview 427
What Eye Movements Accomplish 427
The Actions and Innervation of Extraocular
Muscles 428
BOX A The Perception of Stabilized Retinal Images
430
Types of Eye Movements and Their Functions 431
Neural Control of Saccadic Eye Movements 433
BOX B Sensory Motor Integration in the Superior
Colliculus 438
Neural Control of Smooth Pursuit Movements 440
Neural Control of Vergence Movements 440
Summary 440
21. The Visceral Motor System 443
Overview 443
Early Studies of the Visceral Motor System 443
The Sympathetic Division of the Visceral Motor
System 444
The Parasympathetic Division of the Visceral
Motor System 447
The Enteric Nervous System 450
Sensory Components of the Visceral Motor System
453
Central Control of the Visceral Motor Functions 454
Neurotransmission in the Visceral Motor System 454
BOX A The Hypothalamus 456
BOX B Horner s Syndrome 458
Visceral Motor Reflex Functions 460
Autonomic Regulation of Cardiovascular Function
460
Autonomic Regulation of the Bladder 462
Autonomic Regulation of Sexual Function 464
Summary 466
Unit IV nfaM THE CHANC
22. Early Brain Development 471
Overview 471
The Initial Formation of the Nervous System:
Gastrulation and Neurulation 471
The Molecular Basis of Neural Induction 473
BOX A Retinoic Acid: Teratogen and Inductive
Signal 474
Formation of the Major Brain Subdivisions 476
Genetic Abnormalities and Altered Human
Brain Development 479
The Initial Differentiation of Neurons and Glia 480
BOX B Homeotic Genes and Human Brain
Development 480
BOXC Rhombomeres 482
The Generation of Neuronal Diversity 483
BOX D Neurogenesis and Neuronal Birthdating 486
Neuronal Migration 488
Summary 490
23. Construction of Neural Circuits 493
Overview 493
The Axonal Growth Cone 493
Non-Diffusible Signals for Axon Guidance 494
Diffusible Signals for Axon Guidance:
Chemoattraction and Repulsion 498
The Formation of Topographic Maps 500
Selective Synapse Formation 502
Trophic Interactions and the Ultimate Size
of Neuronal Populations 503
BOX A Molecular Signals That Promote Synapse
Formation 504
Further Competitive Interactions in the
Formation of Neuronal Connections 506
BOX B Why Do Neurons Have Dendrites? 509
Molecular Basis of Trophic Interactions 510
Neurotrophin Receptors 512
BOX C The Discovery of BDNF and the
Neurotrophin Family 514
The Effect of Neurotrophins on the Differentiation
of Neuronal Form 515
Summary 516
Contents xiii
mG BRAIN
24. Modification of Brain Circuits as a
Result of Experience 519
Overview 519
Critical Periods 519
BOX A Built-in Behaviors 520
The Development of Language: A Critical
Period in Humans 521
BOXB Birdsong 522
Critical Periods in Visual System Development 524
Effects of Visual Deprivation on Ocular Dominance
525
BOX C Transneuronal Labeling with Radioactive
Amino Acids 527
Critical Periods, Cortical Plasticity, and
Amblyopia in Humans 530
Mechanisms by which Neuronal Activity Affects
the Development of Neural Circuits 531
Evidence for Critical Periods in Other Sensory
Systems 533
Summary 533
25. Plasticity of Mature Synapses and
Circuits 535
Overview 535
Mechanisms of Synaptic Plasticity in
Relatively Simple Invertebrates 535
Mechanisms of Short-Term Synaptic Plasticity in
the Mammalian Nervous System 539
BOX A Genetics of Learning and Memory in the
Fruit Fly 540
Mechanism of Long-Term Synaptic Plasticity in
the Mammalian Nervous System 541
Long-Term Synaptic Potentiation 542
Molecular Mechanisms Underlying LTP 545
BOX B Silent Synapses 548
Long-Term Synaptic Depression 550
Plasticity in the Adult Cerebral Cortex 553
BOX C Epilepsy: The Effect of Pathological Activity
on Neural Circuitry 554
Recovery from Neural Injury 556
Generation of Neurons in the Adult Brain 559
BOX D Why Aren t We More Like Fish and Frogs?
560
Summary 561
xiv Contents
Unit V W COMPLEX I
26. The Association Cortices 565
Overview 565
The Association Cortices 565
An Overview of Cortical Structure 566
Specific Features of the Association Cortices 568
BOX A A More Detailed Look at Cortical
Lamination 569
Lesions of the Parietal Association Cortex:
Deficits of Attention 571
Lesions of the Temporal Association Cortex:
Deficits of Recognition 574
Lesions of the Frontal Association Cortex:
Deficits of Planning 576
Attention Neurons in the Monkey Parietal
Cortex 577
BOX B Psychosurgery 579
Recognition Neurons in the Monkey Temporal
Cortex 580
Planning Neurons in the Monkey Frontal
Cortex 581
BOX C Neuropsychological Testing 583
BOX D Brain Size and Intelligence 584
Summary 585
27. Language and Lateralization 587
Overview 587
Language Is Both Localized and Lateralized 587
BOX A Do Apes Have Language? 588
Aphasias 590
BOX B Words, Syntax, and Meaning 591
A Dramatic Confirmation of Language
Lateralization 593
Anatomical Differences between the Right
and Left Hemispheres 595
BOX C Handedness 596
Mapping Language Function 597
More on the Role of the Right Hemisphere
in Language 599
Sign Language 600
Summary 601
28. Sleep and Wakefulness 603
Overview 603
Why Do Humans and Many Other Animals Sleep?
603
5RAIN FUNCTIONS
BOX A Styles of Sleep in Different Species 605
The Circadian Cycle of Sleep and Wakefulness 606
BOX B Molecular Mechanisms of Biological Clocks
608
Stages of Sleep 609
Physiological Changes in Sleep States 611
BOX C Electroencephalography 612
The Possible Functions of REM Sleep and
Dreaming 614
Neural Circuits Governing Sleep 615
BOX D Consciousness 616
Thalamocortical Interactions 618
Sleep Disorders 619
Summary 622
29. Emotions 625
Overview 625
Physiological Changes Associated with
Emotion 625
The Integration of Emotional Behavior 626
BOX A Facial Expressions: Pyramidal and
Extrapyramidal Contributions 628
The Limbic System 631
The Importance of the Amygdala 634
BOX B The Anatomy of the Amygdala 634
BOX C The Reasoning Behind an Important
Discovery 636
BOX D Fear and the Human Amygdala: A Case
Study 638
The Relationship between Neocortex and
Amygdala 639
BOX E Affective Disorders 640
Cortical Lateralization of Emotional Functions 642
The Interplay of Emotion and Reason 643
Summary 644
30. Sex, Sexuality, and the Brain 645
Overview 645
Sexually Dimorphic Behavior 645
BOX A The Development of Male and Female
Phenotypes 646
What Is Sex? 647
Hormonal Influences on Sexual Dimorphism 649
BOX B The Case of John/Joan 649
The Effect of Sex Hormones on Neural Circuitry
651
Central Nervous System Dimorphisms Related
to Reproductive Behaviors 652
BOX C The Actions of Sex Hormones 654
Brain Dimorphisms Related to Cognitive Function
660
Hormone-Sensitive Brain Circuits in Adult
Animals 663
Summary 663
31. Human Memory 665
Overview 665
Qualitative Categories of Human Memory 665
Temporal Categories of Memory 666
BOX A Phylogenetic Memory 667
The Importance of Association in Information
Storage 668
Contents xv
BOX B Savant Syndrome 670
Forgetting 671
Brain Systems Underlying Declarative and
Procedural Memories 673
BOX C Clinical Cases That Reveal the Anatomical
Substrate for Declarative Memories 674
The Long-Term Storage of Information 676
BOX D Alzheimer s Disease 678
Memory and Aging 680
Summary 680
Glossary G-1
Illustration Credits IC-1
Index 1-1
|
| any_adam_object | 1 |
| author | Bear, Mark F. Connors, Barry W. Paradiso, Michael A. |
| author_GND | (DE-588)14280858X (DE-588)1107065194 (DE-588)1107068525 |
| author_facet | Bear, Mark F. Connors, Barry W. Paradiso, Michael A. |
| author_role | aut aut aut |
| author_sort | Bear, Mark F. |
| author_variant | m f b mf mfb b w c bw bwc m a p ma map |
| building | Verbundindex |
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| callnumber-subject | QP - Physiology |
| classification_rvk | WW 2200 |
| ctrlnum | (OCoLC)249286046 (DE-599)BVBBV013735218 |
| dewey-full | 612.8 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 612 - Human physiology |
| dewey-raw | 612.8 |
| dewey-search | 612.8 |
| dewey-sort | 3612.8 |
| dewey-tens | 610 - Medicine and health |
| discipline | Biologie Medizin |
| edition | 2. ed. |
| format | Book |
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| genre | 1\p (DE-588)4123623-3 Lehrbuch gnd-content |
| genre_facet | Lehrbuch |
| id | DE-604.BV013735218 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:51:04Z |
| institution | BVB |
| isbn | 0683305964 0781732557 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-009387947 |
| oclc_num | 249286046 |
| open_access_boolean | |
| owner | DE-20 DE-19 DE-BY-UBM DE-188 |
| owner_facet | DE-20 DE-19 DE-BY-UBM DE-188 |
| physical | XXIX, 855 S. Ill., graph. Darst. |
| publishDate | 2001 |
| publishDateSearch | 2001 |
| publishDateSort | 2001 |
| publisher | Lippincott Williams & Wilkins |
| record_format | marc |
| spelling | Bear, Mark F. Verfasser (DE-588)14280858X aut Neuroscience exploring the brain Mark F. Bear ; Barry W. Connors ; Michael A. Paradiso 2. ed. Baltimore, Md. [u.a.] Lippincott Williams & Wilkins 2001 XXIX, 855 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Hirnforschung (DE-588)4123382-7 gnd rswk-swf Neurobiologie (DE-588)4041871-6 gnd rswk-swf Hirnfunktion (DE-588)4159930-5 gnd rswk-swf Neurologie (DE-588)4041888-1 gnd rswk-swf Nervenzelle (DE-588)4041649-5 gnd rswk-swf Gehirn (DE-588)4019752-9 gnd rswk-swf Neurowissenschaften (DE-588)7555119-6 gnd rswk-swf Nervensystem (DE-588)4041643-4 gnd rswk-swf 1\p (DE-588)4123623-3 Lehrbuch gnd-content Nervenzelle (DE-588)4041649-5 s Hirnforschung (DE-588)4123382-7 s Gehirn (DE-588)4019752-9 s Neurobiologie (DE-588)4041871-6 s DE-188 Hirnfunktion (DE-588)4159930-5 s 2\p DE-604 Nervensystem (DE-588)4041643-4 s 3\p DE-604 Neurowissenschaften (DE-588)7555119-6 s 4\p DE-604 Neurologie (DE-588)4041888-1 s 5\p DE-604 Connors, Barry W. Verfasser (DE-588)1107065194 aut Paradiso, Michael A. Verfasser (DE-588)1107068525 aut HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009387947&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 3\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 4\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 5\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Bear, Mark F. Connors, Barry W. Paradiso, Michael A. Neuroscience exploring the brain Hirnforschung (DE-588)4123382-7 gnd Neurobiologie (DE-588)4041871-6 gnd Hirnfunktion (DE-588)4159930-5 gnd Neurologie (DE-588)4041888-1 gnd Nervenzelle (DE-588)4041649-5 gnd Gehirn (DE-588)4019752-9 gnd Neurowissenschaften (DE-588)7555119-6 gnd Nervensystem (DE-588)4041643-4 gnd |
| subject_GND | (DE-588)4123382-7 (DE-588)4041871-6 (DE-588)4159930-5 (DE-588)4041888-1 (DE-588)4041649-5 (DE-588)4019752-9 (DE-588)7555119-6 (DE-588)4041643-4 (DE-588)4123623-3 |
| title | Neuroscience exploring the brain |
| title_auth | Neuroscience exploring the brain |
| title_exact_search | Neuroscience exploring the brain |
| title_full | Neuroscience exploring the brain Mark F. Bear ; Barry W. Connors ; Michael A. Paradiso |
| title_fullStr | Neuroscience exploring the brain Mark F. Bear ; Barry W. Connors ; Michael A. Paradiso |
| title_full_unstemmed | Neuroscience exploring the brain Mark F. Bear ; Barry W. Connors ; Michael A. Paradiso |
| title_short | Neuroscience |
| title_sort | neuroscience exploring the brain |
| title_sub | exploring the brain |
| topic | Hirnforschung (DE-588)4123382-7 gnd Neurobiologie (DE-588)4041871-6 gnd Hirnfunktion (DE-588)4159930-5 gnd Neurologie (DE-588)4041888-1 gnd Nervenzelle (DE-588)4041649-5 gnd Gehirn (DE-588)4019752-9 gnd Neurowissenschaften (DE-588)7555119-6 gnd Nervensystem (DE-588)4041643-4 gnd |
| topic_facet | Hirnforschung Neurobiologie Hirnfunktion Neurologie Nervenzelle Gehirn Neurowissenschaften Nervensystem Lehrbuch |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009387947&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT bearmarkf neuroscienceexploringthebrain AT connorsbarryw neuroscienceexploringthebrain AT paradisomichaela neuroscienceexploringthebrain |