Holdings: Harrison's principles of internal medicine

Harrison's principles of internal medicine:

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Bibliographic Details
Format:	Book
Language:	English
Published:	New York [u.a.] McGraw-Hill 2001
Edition:	15. ed.
Subjects:	Interne geneeskunde Internal Medicine Internal medicine Innere Krankheit Innere Medizin CD-ROM Lehrbuch
Online Access:	Inhaltsverzeichnis
Physical Description:	Getr. Zählung Ill., graph. Darst.
ISBN:	0070072728

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adam_text	CON! Contributors xix Preface xxxi Part One INTRODUCTION TO CLINICAL MEDICINE 1 The Practice of Medicine 1 The Editors 2 Ethical Issues in Clinical Medicine 5 Bernard Lo 3 Decision-Making in Clinical Medicine 8 Daniel B. Mark 4 Economic Issues in Clinical Medicine 14 Daniel B. Mark 5 Influence of Environmental and Occupational Hazards on Disease 19 Howard Hu I Frank E. Speizer 6 Women s Health 21 Anthony L. Komaroff I Celeste Robb-Nicholson I Andrea E. Dunaif 7 Medical Disorders during Pregnancy 25 Robert L. Barbieri I John T. Repke 8 Adolescent Health Problems 31 Mehul T. Dattani I Charles G.D. Brook 9 Geriatric Medicine 36 Neil M. Resnick 10 Principles of Disease Prevention 46 Maureen T.Connelly I Thomas S. Inui 11 Alternative Medicine 49 Adriane Fugh-Berman Part Two CARDINAL MANIFESTATIONS AND PRESENTATION OF DISEASES Section 1 Pain 12 Pain: Pathophysiology and Management 55 Howard L. Fields I Joseph B. Martin 13 Chest Discomfort and Palpitations 60 Thomas H. Lee 14 Abdominal Pain 67 William Silen 15 Headache, Including Migraine and Cluster Headache 70 Neil H. Raskin I Stephen J. Peroutka 16 Back and Neck Pain 79 John W. Engstrom Section 2 Alterations in Body Temperature 17 Fever and Hyperthermia 91 Charles A. Dinarello I Jeffrey A. Gelfand 18 Fever and Rash 95 Elaine T. Kaye I Kenneth M. Kaye 19 Approach to the Acutely 111 Infected Febrile Patient 102 Tamar F. Barlam I Dennis L. Kasper 20 Hypothermia and Frostbite 107 Daniel F. Danzl ^ENTS SKtTION 3 Nervous System Dysfunction 21 Faintness, Syncope, Dizziness, and Vertigo 111 Robert B. Daroff I Mark D. Carlson 22 Weakness, Myalgias, Disorders of Movement, and Imbalance 119 Richard K. Olney I Michael J Aminoff 23 Numbness, Tingling, and Sensory Loss 128 Arthur K. Asbury 24 Acute Confusional States and Coma 132 Allan H. Ropper 25 Aphasias and Other Focal Cerebral Disorders 140 M.-Marsel Mesulam 26 Memory Loss and Dementia 148 Thomas D. Bird 27 Sleep Disorders 155 Charles A. Czeisler I John W. Winkelman I Gary S. Richardson Section 4 Disorders of Eyes, Ears, Nose, and Throat 28 Disorders of the Eye 164 Jonathan C. Horton 29 Disorders of Smell, Taste, and Hearing 179 Anil K. Lalwani I James B. Snow, Jr. 30 Infections of the Upper Respiratory Tract 187 Marlene Durand I Michael Joseph 31 Oral Manifestations of Disease 193 John S. Greenspan Section 5 Alterations in Circulatory and Respiratory Functions 32 Dyspnea and Pulmonary Edema 199 Roland H. Ingram, Jr. I Eugene Braunwald 33 Cough and Hemoptysis 203 Steven E. Weinberger I Eugene Braunwald 34 Approach to the Patient with a Heart Murmur 207 Patrick T. O Gara I Eugene Braunwald 35 Approach to the Patient with Hypertension 211 Gordon H. Williams 36 Hypoxia and Cyanosis 214 Eugene Braunwald 37 Edema 217 Eugene Braunwald 38 Shock 222 Ronald V. Maier 39 Cardiovascular Collapse, Cardiac Arrest, and Sudden Cardiac Death 228 Robert J. Myerburg I Agustin Castellanos Section 6 Alterations in Gastrointestinal Function 40 Dysphagia 233 Raj K. Goyal 41 Nausea, Vomiting, and Indigestion 236 William L. Hosier X Contei 42 Diarrhea and Constipation 241 David A. Ahlquist I Michael Camilleri 43 Weight Loss 250 Carol M. Reife 44 Gastrointestinal Bleeding 252 Loren Laine 45 Jaundice 255 Daniel S. Pratt I Marshall M. Kaplan 46 Abdominal Swelling and Ascites 260 Robert M. Glickman Section 7 Alterations in Renal and Urinary Tract Function 47 Azotemia and Urinary Abnormalities 262 Bradley M. Denker I Barry M. Brenner 48 Incontinence and Lower Urinary Tract Symptoms 268 Philippe E. Zimmern I John D. McConnell 49 Fluid and Electrolyte Disturbances 271 Gary G. Singer I Barry M. Brenner 50 Acidosis and Alkalosis 283 Thomas D. DuBose, Jr. Section 8 Alterations in Sexual Function and Reproduction 51 Erectile Dysfunction 291 Kevin T. McVary 52 Disturbances of Menstruation and Other Common Gynecologic Complaints in Women 295 Bruce R. Carr I Karen D. Bradshaw 53 Hirsutism and Virilization 297 David A. Ehrmann 54 Infertility and Fertility Control 301 Janet E. Hall Section 9 Alterations in the Skin 55 Approach to the Patient with a Skin Disorder 305 Thomas J. Lawley I Kim B. Yancey 56 Eczema, Psoriasis, Cutaneous Infections, Acne, and Other Common Skin Disorders 309 Robert A. Swerlick I Thomas J. Lawley 57 Skin Manifestations of Internal Disease 315 Jean L. Bolognia I Irwin M. Braverman 58 Immunologically Mediated Skin Diseases 331 Kim B. Yancey I Thomas J. Lawley 59 Cutaneous Drug Reactions 336 Robert S. Stern I Olivier M. Chosidow I Bruce U. Wintroub 60 Photosensitivity and Other Reactions to Light 342 David R. Bickers Section 10 Hematologic Alterations 61 Anemia and Polycythemia 348 John W. Adamson I Dan L. Longo 62 Bleeding and Thrombosis 354 Robert I. Handin 63 Enlargement of the Lymph Nodes and Spleen 360 Patrick H. Henry I Dan L. Longo 64 Disorders of Granulocytes and Monocytes 366 Steven M. Holland I John I. Gallin its _^ Nobel Prize in Physiology or Medicine, 1990 374 Joseph Edward Murray I Edward Donnall Thomas Part Three GENETICS AND DISEASE 65 Principles of Human Genetics 375 J. Larry Jameson I Peter Kopp 66 Chromosome Disorders 396 Terry Hassold I Stuart Schwartz 67 Diseases Caused by Genetic Defects of Mitochondria 404 Donald R. Johns 68 Screening, Counseling, and Prevention of Genetic Disorders 407 Susan Miesfeldt I J. Larry Jameson 69 Gene Therapy 412 Mark A. Kay I David W. Russell Nobel Prize in Physiology or Medicine, 1905 418 Robert Koch Part Four CLINICAL PHARMACOLOGY 70 Principles of Drug Therapy 419 John A. Oates I Dan M. Roden I Grant R. Wilkinson 71 Adverse Reactions to Drugs 430 Alastair J.J. Wood 72 Physiology and Pharmacology of the Autonomic Nervous System 438 Lewis Landsberg I James B. Young Part Five NUTRITION 73 Nutritional Requirements and Dietary Assessment 451 Johanna Dwyer 74 Malnutrition and Nutritional Assessment 455 Charles H. Hoisted 75 Vitamin and Trace Mineral Deficiency and Excess 461 Robert M. Russell 76 Enteral and Parenteral Nutrition Therapy 470 Lyn Howard 11 Obesity 479 Jeffrey S. Flier 78 Eating Disorders 486 B. Timothy Walsh Part Six ONCOLOGY AND HEMATOLOGY Section 1 Neoplastic Disorders 79 Approach to the Patient with Cancer 491 Dan L. Longo 80 Prevention and Early Detection of Cancer 497 Otis W. Brawley I Barnett S. Kramer 81 Cancer Genetics 503 Francis S. Collins I Jeffrey M. Trent 82 Cell Biology of Cancer 509 Robert G. Fenton I Dan L. Longo 83 Angiogenesis 517 Judah Folkman Com 84 Principles of Cancer Treatment 530 Edward A. Sausville I Dan L. Longo 85 Infections in Patients with Cancer 547 Robert Finberg 86 Melanoma and Other Skin Cancers 554 Arthur J. Sober I Howard K. Koh I Gregory P. Wittenberg I Carl V. Washington, Jr. 87 Head and Neck Cancer 559 Everett E. Vokes 88 Neoplasms of the Lung 562 John D. Minna 89 Breast Cancer 571 Marc E. Lippman 90 Gastrointestinal Tract Cancer 578 Robert J. Mayer 91 Tumors of the Liver and Biliary Tract 588 Jules L. Dienstag I Kurt J. Isselbacher 92 Pancreatic Cancer 591 Robert J. Mayer 93 Endocrine Tumors of the Gastrointestinal Tract and Pancreas 593 Robert T. Jensen 94 Bladder and Renal Cell Carcinomas 604 Howard I. Scher I Robert J. Motzer 95 Hyperplastic and Malignant Diseases of the Prostate 608 Howard I. Scher 96 Testicular Cancer 616 Robert J. Motzer I George J. BosI 97 Gynecologic Malignancies 620 Robert C. Young 98 Soft Tissue and Bone Sarcomas and Bone Metastases 625 Shreyaskumar R. Patel I Robert S. Benjamin 99 Metastatic Cancer of Unknown Primary Site 628 Richard M. Stone 100 Paraneoplastic Syndromes 632 BruceE. Johnson 101 Paraneoplastic Neurologic Syndromes 636 Muhammad T. Al-Lozi I Alan Pestronk 102 Oncologic Emergencies 642 Rasim Gucalp I Janice Dutcher 103 Late Consequences of Cancer and Its Treatment 650 Michael C. Perry I Dan L. Longo Section 2 Disorders of Hematopoiesis 104 Hematopoiesis 653 Peter J. Quesenberry I Gerald A. Colvin 105 Iron Deficiency and Other Hypoproliferative Anemias 660 John W. Adamson 106 Hemoglobinopathies 666 Edward J. Benz, Jr. 107 Megaloblastic Anemias 674 Bernard M. Babior I H. Franklin Bunn 108 Hemolytic Anemias and Acute Blood Loss 681 H. Franklin Bunn I Wendell Rosse 109 Aplastic Anemia, Myeiodysplasia, and Related Bone Marrow Failure Syndromes 692 Neal S. Young tents XI 110 Polycythemia Vera and Other Myeloproliferative Diseases 701 Jerry L. Spivak 111 Acute and Chronic Myeloid Leukemia 706 Meir Wetzler I John C. Byrd I Clara D. Bloomfield 112 Malignancies of Lymphoid Cells 715 James O. Armitage I Dan L. Longo 113 Plasma Cell Disorders 727 Dan L. Longo 114 Transfusion Biology and Therapy 733 Jeffery S. Dzieczkowski I Kenneth C. Anderson 115 Bone Marrow and Stem Cell Transplantation 739 Frederick R. Appelbaum Section 3 Disorders of Hemostasis 116 Disorders of the Platelet and Vessel Wall 745 Robert I. Handin 117 Disorders of Coagulation and Thrombosis 751 Robert I. Handin 118 Anticoagulant, Fibrinolytic, and Antiplatelet Therapy 758 Robert I. Handin Nobel Prize in Physiology or Medicine, 1930 761 Karl Landsteiner Nobel Prize in Physiology or Medicine, 1962 762 Francis Harry Compton Crick I James Dewey Watson I Maurice Hugh Frederick Wilkins Part Seven INFECTIOUS DISEASES Section 1 Basic Considerations in Infectious Diseases 119 Introduction to Infectious Diseases: Host-Parasite Interactions 763 Lawrence C. Madoff I Dennis L. Kasper 120 Molecular Mechanisms of Microbial Pathogenesis 767 Gerald B. Pier 121 Laboratory Diagnosis of Infectious Diseases 775 Andrew B. Onderdonk 122 Immunization Principles and Vaccine Use 780 Gerald T. Keusch I Kenneth J. Bart 123 Health Advice for International Travel 793 J.S. Keystone I P.E. Kozarsky Section 2 Clinical Syndromes: Community-Acquired Infections 124 Sepsis and Septic Shock 799 Robert S. Munford 125 Fever of Unknown Origin 804 Jeffrey A. Gelfand 126 Infective Endocarditis 809 Adolf W. Karchmer 127 Infectious Complications of Bites and Burns 817 Lawrence C. Madoff XH Conte 128 Infections of the Skin, Muscle, and Soft Tissues 821 Dennis L. Stevens 129 Osteomyelitis 825 James H. Maguire 130 Intraabdominal Infections and Abscesses 829 Dori F. Zaleznik I Dennis L. Kasper 131 Acute Infectious Diarrheal Diseases and Bacterial Food Poisoning 834 Joan R. Butterton I Stephen B. Calderwood 132 Sexually Transmitted Diseases: Overview and Clinical Approach 839 King K. Holmes 133 Pelvic Inflammatory Disease 848 King K. Holmes I Robert C. Brunham Section 3 Clinical Syndromes: Nosocomial Infections 134 Infection Control in the Hospital 853 Robert A. Weinstein 135 Hospital-Acquired and Intravascular Device-Related Infections 857 Dori F. Zaleznik 136 Infections in Transplant Recipients 860 Robert Finberg I Joyce D. Fingeroth Section 4 Approach to Therapy for Bacterial Diseases 137 Treatment and Prophylaxis of Bacterial Infections 867 Gordon L. Archer I Ronald E. Polk Section 5 Diseases Caused by Gram-Positive Bacteria 138 Pneumococcal Infections 882 Daniel M. Musher 139 Staphylococcal Infections 889 Jeffrey Parsonnet I Robert L. Deresiewicz 140 Streptococcal and Enterococcal Infections 901 Michael R. Wessels 141 Diphtheria, Other Corynebacterial Infections, and Anthrax 909 Randall K. Holmes 142 Infections Caused by Listeria monocytogenes 915 Anne Schuchat I Claire V. Broome 143 Tetanus 918 Elias Abrutyn 144 Botulism 920 Elias Abrutyn 145 Gas Gangrene, Antibiotic-Associated Colitis, and Other Clostridial Infections 922 Dennis L. Kasper I Dori F. Zaleznik Section 6 Diseases Caused by Gram-Negative Bacteria 146 Meningococcal Infections 927 Robert S. Munford 147 Gonococcal Infections 931 Sanjay Ram I Peter A. Rice 148 Moraxella catarrhalis and Other Moraxella Species 938 Daniel M. Musher nts __ 149 Haemophilus Infections 939 Timothy F. Murphy 150 Infections due to the HACEK Group and Miscellaneous Gram-Negative Bacteria 942 Dennis L. Kasper I Tamar F. Barlam 151 Legionella Infection 945 Feng-Yee Chang I Victor L. Yu 152 Pertussis and Other Bordetella Infections 949 Scott A. Halperin 153 Diseases Caused by Gram-Negative Enteric Bacilli 953 Thomas A. Russo 154 Helicobacter pylori Infections 960 John C. Atherton I Martin J. Blaser 155 Infections due to Pseudomonas Species and Related Organisms 963 Christopher A. Ohl I Matthew Pollack 156 Salmonellosis 970 Cammie F. Lesser I Samuel I. Miller 157 Shigellosis 975 Gerald T. Keusch 158 Infections due to Campylobacter and Related Species 978 Martin J. Blaser 159 Cholera and Other Vibrioses 980 Gerald T. Keusch I Matthew K. Waldor 160 Brucellosis 986 M. Monir Madkour I Dennis L. Kasper 161 Tularemia 990 Richard F. Jacobs 162 Plague and Other Yersinia Infections 993 Grant L. Campbell I David T. Dennis 163 Bartonella Infections, Including Cat-Scratch Disease 1001 Lucy Stuart Tompkins 164 Donovanosis 1004 Gavin Hart Section 7 Miscellaneous Bacterial Infections 165 Nocardiosis 1006 Gregory A. Filice 166 Actinomycosis 1008 Thomas A. Russo 167 Infections due to Mixed Anaerobic Organisms 1011 Dennis L. Kasper Section 8 Mycobacterial Diseases 168 Antimycobacterial Agents 1017 Paul W. Wright I Richard J. Wallace, Jr. 169 Tuberculosis 1024 Mario C. Raviglione I Richard J. O Brien 170 Leprosy (Hansen s Disease) 1035 Robert H. Gelber 171 Infections due to Nontuberculous Mycobacteria 1040 Bernard Hirschel Section 9 Spirochetal Diseases 172 Syphilis 1044 Sheila A. Lukehart 173 Endemic Treponematoses 1053 Sheila A. Lukehart 174 Leptospirosis 1055 Peter Speelman 175 Relapsing Fever 1058 David T. Dennis I Grant L. Campbell 176 Lyme Borreliosis 1061 Allen C. Steere Section 10 rlckettsia, mycoplasma, and chlamydia 177 Rickettsial Diseases 1065 David Walker I Didier Raoult I J. Stephen Dumler I Thomas Marrie 178 Mycoplasma Infections 1073 William M. McCormack 179 Chlamydial Infections 1075 Walter E. Stamm Section 11 Viral Diseases 180 Medical Virology 1084 Fred Wang I Elliott Kieff 181 Antiviral Chemotherapy, Excluding Antiretroviral Drugs 1092 Raphael Dolin Section 12 DNA Viruses 182 Herpes Simplex Viruses 1100 Lawrence Corey 183 Varicella-Zoster Virus Infections 1106 Richard J. Whitley 184 Epstein-Barr Virus Infections, Including Infectious Mononucleosis 1109 Jeffrey I. Cohen 185 Cytomegalovirus and Human Herpesvirus Types 6, 7, and 8 1111 Martin S. Hirsch 186 Smallpox, Vaccinia, and Other Poxviruses 1115 Fred Wang 187 Parvovirus 1117 Neil R. Blacklow 188 Human Papillomaviruses 1118 Richard C. Reichman Section 13 DNA and RNA Respiratory Viruses 189 Common Viral Respiratory Infections 1120 Raphael Dolin 190 Influenza 1125 Raphael Dolin Section 14 RNA Viruses 191 The Human Retroviruses 1131 Anthony S. Fauci I Dan L. Longo 192 Viral Gastroenteritis 1135 Harry B. Greenberg 193 Enteroviruses and Reoviruses 1138 Jeffrey I. Cohen tenis AIM 194 Measles (Rubeola) 1143 Anne Gershon 195 Rubella (German Measles) 1145 Anne Gershon 196 Mumps 1147 Anne Gershon 197 Rabies Virus and Other Rhabdoviruses 1149 Lawrence Corey 198 Infections Caused by Arthropod- and Rodent-Borne Viruses 1152 C.J. Peters 199 Filoviridae (Marburg and Ebola Viruses) 1166 C.J. Peters Color Atlases/1168 Section 15 Fungal and Algal Infections 200 Diagnosis and Treatment of Fungal Infections 1168 John E. Bennett 201 Histoplasmosis 1171 John E. Bennett 202 Coccidioidomycosis 1172 John E. Bennett 203 Blastomycosis 1173 John E. Bennett 204 Cryptococcosis 1174 John E. Bennett 205 Candidiasis 1176 John E. Bennett 206 Aspergillosis 1178 John E. Bennett 207 Mucormycosis 1179 John E. Bennett 208 Miscellaneous Mycoses and Algal Infections 1180 John E. Bennett 209 Pneumocystis carinii Infection 1182 Peter D. Water Section 16 Protozoal and Helminthic Infections: General Considerations 210 Approach to the Patient with Parasitic Infection 1185 Peter F. Weller 211 Laboratory Diagnosis of Parasitic Infections 1186 Charles E. Davis 212 Therapy for Parasitic Infections 1192 Thomas A. Moore Section 17 Protozoal Infections 213 Amebiasis and Infection with Free-Living Amebas 1199 Sharon L. Reed 214 Malaria and Babesiosis: Diseases Caused by Red Blood Cell Parasites 1203 Nicholas J. White I Joel G. Breman 215 Leishmaniasis 1213 Barbara L. Herwaldt 216 Trypanosomiasis 1218 Louis V. Kirchhoff XJV lonie 217 Toxoplasma Infection 1222 Lloyd H. Kasper 218 Protozoal Intestinal Infections and Trichomoniasis 1227 Peter F. Welter Section 18 Hfxminthic Infections 219 Trichinella and Other Tissue Nematodes 1231 Leo X. Liu I Peter F. Welter 220 Intestinal Nematodes 1233 Peter F. Welter I Thomas B. Nutman 221 Filariasis and Related Infections (Loiasis, Onchocerciasis, and Dracunculiasis) 1237 Thomas B. Nutman I Peter F. Welter 222 Schistosomiasis and Other Trematode Infections 1242 Adel A.F. Mahmoud 223 Cestodes 1248 A. Clinton White, Jr. I Peter F. Welter Nobel Prize in Physiology or Medicine, 1945 1252 Alexander Fleming I Howard Florey I Ernst Chain Part Eight DISORDERS OF THE CARDIOVASCULAR SYSTEM Section 1 Diagnosis 224 Approach to the Patient with Heart Disease 1253 Eugene Braunwald 225 Physical Examination of the Cardiovascular System 1255 Robert A. O Rourke I Eugene Braunwald 226 Electrocardiography 1262 Ary L. Goldberger 227 Noninvasive Cardiac Imaging: Echocardiography and Nuclear Cardiology 1271 Rick A. Nishimura I Raymond J. Gibbons I A. Jamil Tajik 228 Diagnostic Cardiac Catheterization and Angiography 1277 Donald S. Bairn I William Grossman Section 2 Disorders of Rhythm 229 The Bradyarrhythmias: Disorders of Sinus Node Function and AV Condition Disturbances 1283 Mark E. Josephson I Peter Zimetbaum 230 The Tachyarrhythmias 1292 Mark E. Josephson I Peter Zimetbaum Section 3 Disorders of the Heart 231 Normal and Abnormal Myocardial Function 1309 Eugene Braunwald 232 Heart Failure 1318 Eugene Braunwald 233 Cardiac Transplantation 1329 John S. Schroeder 234 Congenital Heart Disease in the Adult 1331 William F. Friedman I John S. Child 235 Rheumatic Fever 1340 Edward L. Kaplan ills 236 Valvular Heart Disease 1343 Eugene Braunwald 237 Cor Pulmonale 1355 Eugene Braunwald 238 The Cardiomyopathies and Myocarditides 1359 Joshua Wynne I Eugene Braunwald 239 Pericardial Disease 1365 Eugene Braunwald 240 Cardiac Tumors, Cardiac Manifestations of Systemic Diseases, and Traumatic Cardiac Injury 1372 Wilson S. Colucci I Daniel T. Price Section 4 Vascular Disease 241 The Pathogenesis of Atherosclerosis 1377 Peter Libby I M Prevention and Treatment of Atherosclerosis 1382 Peter Libby 243 Acute Myocardial Infarction 1386 Elliott M. Antman I Eugene Braunwald 244 Ischemic Heart Disease 1399 Andrew P. Selwyn I Eugene Braunwald 245 Percutaneous Coronary Revascularization 1410 Donald S. Bairn 246 Hypertensive Vascular Disease 1414 Gordon H. Williams 247 Diseases of the Aorta 1430 Victor J. Dzau I Mark A. Creager 248 Vascular Diseases of the Extremities 1434 Mark A. Creager I Victor J. Dzau Part Nine DISORDERS OF THE RESPIRATORY SYSTEM Section 1 Diagnosis 249 Approach to the Patient with Disease of the Respiratory System 1443 Jeffrey M. Drazen I Steven E. Weinberger 250 Disturbances of Respiratory Function 1446 Steven E. Weinberger I Jeffrey M. Drazen 251 Diagnostic Procedures in Respiratory Disease 1453 Steven E. Weinberger I Jeffrey M. Drazen Section 2 Diseases of the Respiratory System 252 Asthma 1456 E.R. McFadden, Jr. 253 Hypersensitivity Pneumonitis and Pulmonary Infiltrates with Eosinophilia 1463 Joel N. Kline I Gary W. Hunninghake 254 Environmental Lung Diseases 1467 Frank E. Speizer 255 Pneumonia, Including Necrotizing Pulmonary Infections (Lung Abscess) 1475 Matthew E. Levison 256 Bronchiectasis 1485 Steven E. Weinberger con 257 Cystic Fibrosis 1487 Richard C. Boucher 258 Chronic Bronchitis, Emphysema, and Airways Obstruction 1491 Eric G. Honig I Roland H. Ingram, Jr. 259 Interstitial Lung Diseases 1499 Talmadge E. King, Jr. 260 Primary Pulmonary Hypertension 1506 Stuart Rich 261 Pulmonary Thromboembolism 1508 Samuel Z. Goldhaber 262 Disorders of the Pleura, Mediastinum, and Diaphragm 1513 Richard W. Light 263 Disorders of Ventilation 1517 Eliot A. Phillipson 264 Sleep Apnea 1520 Eliot A. Phillipson 265 Acute Respiratory Distress Syndrome 1523 Marc Moss I Roland H. Ingram, Jr. 266 Mechanical Ventilatory Support 1526 Edward P. Ingenito I Jeffrey M. Drazen 267 Lung Transplantation 1531 Janet R. Maurer Nobel Prize in Physiology or Medicine, 1985 1534 Michael Stuart Brown I Joseph Leonard Goldstein Part Ten DISORDERS OF THE KIDNEY AND URINARY TRACT 268 Disturbances of Renal Function 1535 Robert M. Brenner I Barry M. Brenner 269 Acute Renal Failure 1541 Hugh R. Brady I Barry M. Brenner TJQ Chronic Renal Failure 1551 Karl Skorecki I Jacob Green I Barry M. Brenner 271 Dialysis in the Treatment of Renal Failure 1562 Ajay K. Singh I Barry M. Brenner 272 Transplantation in the Treatment of Renal Failure 1567 Charles B. Carpenter I Edgar L. Milford I Mohamed H. Sayegh 273 Pathogenesis of Glomerular Injury 1572 Hugh R. Brady I Barry M. Brenner 21A The Major Glomerulopathies 1580 Hugh R. Brady I Yvonne M. O Meara I Barry M. Brenner 275 Glomerulopathies Associated with Multisystem Diseases 1590 Yvonne M. O Meara I Hugh R. Brady I Barry M. Brenner 276 Hereditary Tubular Disorders 1598 John R. Asplin I Fredric L. Coe 277 Tubulointerstitial Diseases of the Kidney 1606 Alan S.L. Yu I Barry M. Brenner 278 Vascular Injury to the Kidney 1610 Kamal F. Badr I Barry M. Brenner 279 Nephrolithiasis 1615 John R. Asplin I Fredric L. Coe I Murray J. Favus 280 Urinary Tract Infections and Pyelonephritis 1620 Walter E. Stamm tents XV 281 Urinary Tract Obstruction 1627 Julian L. Seifter I Barry M. Brenner Nobel Prize in Physiology or Medicine, 1956 1630 Werner Iheodor Olio Forssmann I Andre Frederic Coiinuind Dickinson Woodruff Richards. Jr. Part Eleven DISORDERS OF THE GASTROINTESTINAL SYSTEM Section 1 Disorders of the Alimentary Tract 282 Approach to the Patient with Gastrointestinal Disease 1631 Daniel K. Podolsky I Kurt J. Isselbacher 283 Gastrointestinal Endoscopy 1635 Mark Topazian 284 Diseases of the Esophagus 1642 Raj K. Goyal 285 Peptic Ulcer Disease and Related Disorders 1649 John Del Valle 286 Disorders of Absorption 1665 Henry J. Binder 287 Inflammatory Bowel Disease 1679 Sonia Friedman I Richard S. Blumberg 288 Irritable Bowel Syndrome 1692 Chung Owyang 289 Diverticular, Vascular, and Other Disorders of the Intestine and Peritoneum 1695 Kurt J. Isselbacher I Alan Epstein 290 Acute Intestinal Obstruction 1703 William Silen 291 Acute Appendicitis 1705 William Silen Section 2 Liver and Biliary Tract Disease 292 Approach to the Patient with Liver Disease 1707 Marc Ghany I Jay H. Hoofnagle 293 Evaluation of Liver Function 1711 Daniel S. Pratt I Marshall M. Kaplan 294 Bilirubin Metabolism and the Hyperbilirubinemias 1715 Paul D. Berk I Allan W. Wolkoff 295 Acute Viral Hepatitis 1721 Jules L. Dienstag I Kurt J. Isselbacher 296 Toxic and Drug-Induced Hepatitis 1737 Jules L. Dienslag I Kurt J. Isselbacher 297 Chronic Hepatitis 1742 Jules L. Dienslag I Kurt J. Isselbacher 298 Alcoholic Liver Disease 1752 Mark E. Mailliard I Michael F. Sorrell 299 Cirrhosis and Its Complications 1754 Raymond T. Chung I Daniel K. Podolsky 300 Infiltrative, Genetic, and Metabolic Diseases Affecting the Liver 1767 Daniel K. Podolsky 301 Liver Transplantation 1770 Jules L. Dienstag XVI *- ¦ 302 Diseases of the Gallbladder and Bile Ducts 1776 Norton J. Greenberger / Gustav Paumgartner Section 3 Disorders oe the Pancreas 303 Approach to the Patient with Pancreatic Disease 1788 Phillip P. Toskes I Norton ./. Greenberger 304 Acute and Chronic Pancreatitis 1792 Norton ./. Greenberger I Phillip P. Toskes Part Twelve DISORDERS OF THE IMMUNE SYSTEM, CONNECTIVE TISSUE, AND JOINTS Section 1 Disorders oe the Immune System 305 Introduction to the Immune System 1805 Barton F. Haynes I Anthony S. Fauci 306 The Major Histocompatibility Gene Complex 1830 Gerald T. Nepom I Joel D. Taurog 307 Autoimmunity and Autoimmune Diseases 1839 Peter E. Lipsky I Betty Diamond 308 Primary Immune Deficiency Diseases 1843 Max D. Cooper I Harry W. Schroeder, Jr. 309 Human Immunodeficiency Virus (HIV) Disease: AIDS and Related Disorders 1852 Anthony S. Fauci I H. Clifford Lane Section 2 Disorders oe Immune-Mediated Injury 310 Allergies, Anaphylaxis, and Systemic Mastocytosis 1913 K. Frank Austen 311 Systemic Lupus Erythematosus 1922 Bevra Hannahs Hahn 312 Rheumatoid Arthritis 1928 Peter E. Lipsky 313 Systemic Sclerosis (Scleroderma) 1937 Bruce C. Gilliland 314 Sjogren s Syndrome 1947 Haralampos M. Moutsopoulos 315 Ankylosing Spondylitis, Reactive Arthritis, and Undifferentiated Spondyloarthropathy 1949 Joel D. Taurog I Peter E. Lipsky 316 Behget s Syndrome 1956 Haralampos M. Moutsopoulos 317 The Vasculitis Syndromes 1956 Anthony S. Fauci 318 Sarcoidosis 1969 Ronald G. Crystal 319 Amyloidosis 1974 Jean D. Sipe, Alan S. Cohen Section 3 Disorders oe the Joints 320 Approach to Articular and Musculoskeletal Disorders 1979 John J. Cush I Peter E. Lipsky 321 Osteoarthritis 1987 Kenneth D. Brandt 322 Gout and Other Crystal Arthropathies 1994 Antonio J. Reginato 323 Infectious Arthritis 1998 Scott J. Thaler I James H. Maguire 324 Psoriatic Arthritis and Arthritis Associated with Gastrointestinal Disease 2003 Peter H. Schur 325 Relapsing Polychondritis and Other Arthritides 2005 Bruce C. Gilliland 326 Periarticular Disorders of the Extremities 2016 Bruce C. Gilliland Part Thirteen ENDOCRINOLOGY AND METABOLISM Section 1 Endocrinology 327 Principles of Endocrinology 2019 /. Larry Jameson 328 Disorders of the Anterior Pituitary and Hypothalamus 2029 Shlomo Melmed 329 Disorders of the Neurohypophysis 2052 Gary L. Robertson 330 Disorders of the Thyroid Gland 2060 /. Larry Jameson I Anthony P. Weetman 331 Disorders of the Adrenal Cortex 2084 Gordon H. Williams I Robert G. Dluhy 332 Pheochromocytoma 2105 Lewis Landsberg I James B. Young 333 Diabetes Mellitus 2109 Alvin C. Powers 334 Hypoglycemia 2138 Philip E. Cryer 335 Disorders of the Testes 2143 James E. Griffin I Jean D. Wilson 336 Disorders of the Ovary and Female Reproductive Tract 2154 Bruce R. Carr I Karen D. Bradshaw 337 Endocrine Disorders of the Breast 2168 Jean D. Wilson 338 Disorders of Sexual Differentiation 2172 Jean D. Wilson I James E. Griffin 339 Disorders Affecting Multiple Endocrine System 2184 Steven I. Sherman I Robert F. Gagel Section 2 Disorders of Bone and Mineral Metabolism 340 Introduction to Bone and Mineral Metabolism 2192 Michael F. Holick I Stephen M. Krane 341 Diseases of the Parathyroid Gland and Other Hyper- and Hypocalcemic Disorders 2205 John T. Potts, Jr. 342 Osteoporosis 2226 Robert Lindsay I Felicia Cosman 343 Paget s Disease and Other Dysplasias of Bone 2237 Stephen M. Krane I Alan L. Schiller Section 3 Disorders of Intermediary Metabolism 344 Disorders of Lipoprotein Metabolism 2245 Henry N. Ginsberg I Ira J. Goldberg Con 345 Hemochromatosis 2257 Lawrie W. Powell I Kurt J. Isselbacher 346 The Porphyrias 2261 RobertJ. Desnick 347 Disorders of Purine and Pyrimidine Metabolism 2268 Robert L. Wortmann 348 Wilson s Disease 2274 /. Herbert Scheinberg 349 Lysosomal Storage Diseases 2276 Gregory A. Grabowski 350 Glycogen Storage Diseases and Other Inherited Disorders of Carbohydrate Metabolism 2281 Yuan-Tsong Chen 351 Inherited Disorders of Connective Tissue 2290 Darwin J. Prockop I Helena Kuivaniemi I Gerard Tromp I Leena Ala-Kokko 352 Inherited Disorders of Amino Acid Metabolism and Storage 2301 Nicola Longo 353 Inherited Defects of Membrane Transport 2309 Nicola Longo 354 The Lipodystrophies and Other Primary Disorders of Adipose Tissue 2316 Abhimanyu Garg Nobel Prize in Physiology or Medicine, 1923 2320 Frederick G. Banting I John JR. Macleod Part Fourteen NEUROLOGIC DISORDERS Section 1 Diagnosis ok Neurologic Disorders 355 Neurobiology of Disease 2321 Stephen L. Hauser I M. Flint Beal 356 Approach to the Patient with Neurologic Disease 2326 Joseph B. Martin I Stephen L. Hauser 357 Electrophysiologic Studies of the Central and Peripheral Nervous Systems 2331 Michael J. Aminoff 358 Neuroimaging in Neurologic Disorders 2337 William P. Dillon 359 Molecular Diagnosis of Neurologic Disorders 2342 Joseph B. Martin I Frank M. Longo Section 2 Diseases of the Central Nervous System 360 Seizures and Epilepsy 2354 Daniel H. Lowenstein 361 Cerebrovascular Diseases 2369 Wade S. Smith I Stephen L. Hauser I J. Donald Easton 362 Alzheimer s Disease and Other Primary Dementias 2391 Thomas D. Bird 363 Parkinson s Disease and Other Extrapyramidal Disorders 2399 Michael J. Aminoff 364 Ataxic Disorders 2406 Roger N. Rosenberg 365 Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases 2412 Robert H. Brown, Jr. tents XVII 366 Disorders of the Autonomic Nervous System 2416 John W. Engstram I Joseph It Martin 367 Common Disorders of the Cranial Nerves 2421 M. Flint Heal I Stephen L. Mauser 368 Diseases of the Spinal Cord 2425 Stephen I. llauser 369 Traumatic Injuries of the Head and Spine 2434 Allun If. Rapper 370 Primary and Metastatic Tumors of the Nervous System 2442 Stephen M. Sugar I Mark A. Israel 371 Multiple Sclerosis and Other Demyelinating Diseases 2452 Stephen L. Mauser I Donald E. Goodkin 372 Bacterial Meningitis and Other Suppurative Infections 2462 Karen L. Roos I Kenneth L. Tyler 373 Viral Meningitis and Encephalitis 2471 Kenneth L. Tyler 374 Chronic and Recurrent Meningitis 2481 Walter J. Koroshetz I Morton N. Swart: 375 Prion Diseases 2486 Stanley B. Prusiner I Patrick Basque 376 Critical Care Neurology 2491 /. Claude Hemphill I M. Flint Beat I Daryl R. Gress Section 3 Disorders of Nerve and Mi sci.es 377 Approach to the Patient with Peripheral Neuropathy 2498 Arthur K. Ashury 378 Guillain-Barre Syndrome and Other Immune-Mediated Neuropathies 2507 Arthur K. Asbury I Stephen L. liauser 379 Charcot-Marie-Tooth Disease and Other Inherited Neuropathies 2512 Phillip F. Chance I Thomas D. Bird 380 Myasthenia Gravis and Other Diseases of the Neuromuscular Junction 2515 Daniel B. Drachman 381 Approach to the Patient with Muscle Disease 2520 Jerry R. Mendell 382 Polymyositis, Dermatomyositis, and Inclusion Body Myositis 2524 Marinas C. Dalakas, Jr. 383 Muscular Dystrophies and Other Muscle Diseases 2529 Robert H. Brown, Jr. I Jerry R. Mendell Section 4 Chronic Fatk;i i; Syndrome 384 Chronic Fatigue Syndrome 2541 Stephen E Straus Section 5 Psychiatric Disorders 385 Mental Disorders 2542 Victor I. Reus Section 6 Alcoholism and Dri c; Dependency 386 Biology of Addiction 2557 Robert O. Messing XVIII ^»... I 387 Alcohol and Alcoholism 2561 Marc A. Schuckit 388 Opioid Drug Abuse and Dependence 2567 Marc A. Schuckit I David S. Segal 389 Cocaine and Other Commonly Abused Drugs 2570 Jack H. Mendelson I Nancy K. Mello 390 Nicotine Addiction 2574 David M. Burns Nobel Prize in Physiology or Medicine, 1924 2577 Willcm Einlliovcn Nobel Prize in Physiology or Medicine, 1929 2578 Clirisliatm Eijbnan. Jr. I Frederick Gowland Part Fifteen ENVIRONMENTAL AND OCCUPATIONAL HAZARDS Section 1 Specific Environmental and Occupational Hazards 391 Specific Environmental and Occupational Hazards 2579 Howard Hu I Frank E. Speizer 392 Drowning and Near-Drowning 2581 Jerome H. Model! 393 Electrical Injuries 2583 Raphael C. Lee 394 Radiation Injury 2585 Stephen M. Hahn I Eli Glatstein 395 Heavy Metal Poisoning 2590 Howard Hu Section 2 Illnesses due to Poisons, Drug Overdosage, and envenomation 396 Poisoning and Drug Overdosage 2595 Christopher H. Linden I Michael J. Burns 397 Disorders Caused by Reptile Bites and Marine Animal Exposures 2616 Robert L. Norris I Paul S. Auerbach 398 Ectoparasite Infestations, Arthropod Bites and Stings 2622 James H. Maguire I Andrew Spielman Nobel Prize in Physiology or Medicine, 1977 2629 Roger Guillemin I Andrew ictor Schallx I Rosalyn Sussman Yalow APPENDICES Appendix A: Laboratory Values of Clinical Importance A-l Appendix B: Instructions for Collection and Transport A-ll of Specimen Culture INDEX 1-1
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spelling	Harrison's principles of internal medicine eds. Eugene Braunwald ... Principles of internal medicine Internal medicine 15. ed. New York [u.a.] McGraw-Hill 2001 Getr. Zählung Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Interne geneeskunde gtt Internal Medicine Innere Krankheit (DE-588)4072828-6 gnd rswk-swf Innere Medizin (DE-588)4027074-9 gnd rswk-swf CD-ROM (DE-588)4139307-7 gnd rswk-swf (DE-588)4123623-3 Lehrbuch gnd-content Innere Krankheit (DE-588)4072828-6 s DE-604 Innere Medizin (DE-588)4027074-9 s CD-ROM (DE-588)4139307-7 s 1\p DE-604 Harrison, Tinsley R. Sonstige oth Braunwald, Eugene 1929- Sonstige (DE-588)111586534 oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009342040&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk
spellingShingle	Harrison's principles of internal medicine Interne geneeskunde gtt Internal Medicine Internal medicine Innere Krankheit (DE-588)4072828-6 gnd Innere Medizin (DE-588)4027074-9 gnd CD-ROM (DE-588)4139307-7 gnd
subject_GND	(DE-588)4072828-6 (DE-588)4027074-9 (DE-588)4139307-7 (DE-588)4123623-3
title	Harrison's principles of internal medicine
title_alt	Principles of internal medicine Internal medicine
title_auth	Harrison's principles of internal medicine
title_exact_search	Harrison's principles of internal medicine
title_full	Harrison's principles of internal medicine eds. Eugene Braunwald ...
title_fullStr	Harrison's principles of internal medicine eds. Eugene Braunwald ...
title_full_unstemmed	Harrison's principles of internal medicine eds. Eugene Braunwald ...
title_short	Harrison's principles of internal medicine
title_sort	harrison s principles of internal medicine
topic	Interne geneeskunde gtt Internal Medicine Internal medicine Innere Krankheit (DE-588)4072828-6 gnd Innere Medizin (DE-588)4027074-9 gnd CD-ROM (DE-588)4139307-7 gnd
topic_facet	Interne geneeskunde Internal Medicine Internal medicine Innere Krankheit Innere Medizin CD-ROM Lehrbuch
url	http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009342040&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
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