The neuropsychology of anxiety: an enquiry into the functions of the septo-hippocampal system
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| Main Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Oxford
Oxford Univ. Press
2000
|
| Edition: | 2. ed. |
| Series: | Oxford psychology series
33 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XVI, 424 S. graph. Darst. |
| ISBN: | 0198522703 |
Staff View
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| 650 | 4 | |a Anxiety |x Physiological aspects | |
| 650 | 4 | |a Anxiety |x drug therapy | |
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Record in the Search Index
| _version_ | 1804128437118435328 |
|---|---|
| adam_text | Contents
1 OVERVIEW 1
Starting points for the neuropsychology of anxiety 2
Fear versus anxiety 5
The hierarchical defence system 6
The amygdala 8
The septo hippocampal system 9
What is the septo hippocampal system? 14
What does the septo hippocampal system do? 15
A common computational core for septo hippocampal function—Mark 1 18
A common computational core for septo hippocampal function—Mark 2 22
The role of other brain regions 29
Conclusion 36
2 ETHOLOGY AND ANXIETY 37
Ethoexperimental analysis 38
Ethopharmacological analysis 41
The ethology and ethopharmacology of anxiety and fear 42
Some terminological problems 43
3 LEARNING THEORY AND ANXIETY 47
Two process theories of learning 47
Elicited reactions in learning experiments 51
The behavioural inhibition system revisited 52
Conclusions 57
4 THE ANXIOLYTIC DRUGS 58
What are the anxiolytic drugs? 58
Clinical usage 59
The classical anxiolytics 62
Buspirone, ipsapirone 65
Clomipramine and obsessive compulsive disorder 67
Beta blockers 68
Clinical actions of the anxiolytics—a summary 68
Bridging the species gap 70
The behavioural effects of anxiolytic drugs in animals 72
Anxiolytic action—some conclusions 79
xiv Contents
5 A THEORY OF THE BEHAVIOURAL INHIBITION
SYSTEM 83
Evolution, anxiety, and rules of thumb—the search for the
behavioural inhibition system 87
Behavioural inhibition and rules of thumb 91
6 THE NEUROLOGY OF ANXIETY 94
The periaqueductal grey, fight, flight, and freezing 99
The medial hypothalamus and escape 99
The amygdala 100
The defence system—integration 110
Interim conclusions 113
Comparison between the septal, hippocampal, and anxiolytic syndromes 114
The effects of lesions of the noradrenergic and serotonergic systems 118
The cholinergic system 122
The prefrontal cortex and cingulate cortex 122
The prefrontal cortex 125
The cingulate cortex 130
Overview of prefrontal and cingulate cortex 131
Prefrontal and cingulate cortex and anxiety 135
Conclusions 138
7 HIPPOCAMPAL PLACE FIELDS 140
Single unit responses: non spatial tasks 141
Single unit responses: correlations with spatial position 143
The relation between spatial fields and head direction fields 149
Space, discrimination, classical conditioning, and habituation 152
Path integration 153
Topographic mapping of single cell fields 155
Conclusion 157
8 MEMORY AND THE SEPTO HIPPOCAMPAL
SYSTEM 158
Human versus animal amnesia 159
The hippocampus as the crucial site for amnesic deficits 161
Types of memory 163
The effects of delay 165
The role of context 169
A preliminary theory of hippocampal amnesia 174
Relational memory 176
Configural memory 178
Semantic encoding 180
Recognition memory 182
Working memory 184
Temporal buffer 187
Contents xv
Spatial memory 191
Interference: some initial comments 193
The role of the hippocampal formation in memory 202
9 FUNDAMENTALS OF THE SEPTO HIPPOCAMPAL
SYSTEM 204
Anxiolytics and the septo hippocampal system—an overview 205
The defence system 209
The motor/working memory system 213
The emotion system 215
General approach to the septo hippocampal system 218
The anatomy of the septo hippocampal system 218
Long term memory 222
Role of the septo hippocampal system in sensory processing 224
The mismatch detection system 225
Aminergic gating systems 229
Theta activity 231
Conclusion 232
10 A THEORY OF THE SEPTO HIPPOCAMPAL
SYSTEM 233
The theory: some basic assumptions 235
The theory: architecture 241
The theory: mechanism 247
Some scenarios 253
The theta rhythm 269
Conclusion 272
11 SYMPTOMS AND SYNDROMES OF ANXIETY 275
Cognitive effects of anxiolytic drugs 279
Anxiolytic action and the amygdala 281
Humpty Dumpty had a great fall 282
Anxiolytic action and the neocorte 284
The clinical psychology of anxiety 285
Behavioural aspects of anxiety syndromes 287
Cognitive aspects of anxiety syndromes 289
Physiological aspects of anxiety syndromes 290
The theory of anxiety 290
Clinical anxiety and memory 293
A functional typology for defence 294
Panic disorder 297
Specific phobia 303
Post traumatic stress disorder 314
Agoraphobia 319
Social phobia 320
xvi Contents
Generalized anxiety disorder 322
Obsessive—compulsive disorder 324
A typology of the anxiety related disorders 327
Differential diagnosis 329
Conclusion 331
12 PUTTING HUMPTY DUMPTY TOGETHER
AGAIN: THE ANXIOUS PERSONALITY AND
ITS INHERITANCE 333
The anxious personality 333
Neuroticism vs. trait anxiety 335
The genetics of neuroticism and emotionality 342
13 THE TREATMENT OF ANXIETY 350
Behaviour therapy 350
Drug therapy 354
Cognitive behavioural therapy 357
Coda 364
REFERENCES 368
INDEX 419
APPENDICES
The appendices are located on the internet at http://www.oup.CO.uk/neuropsych_anxiety
Appendix 1: The behavioural profile of anxiolytic drugs
Appendix 2: The periaqueductal grey, medial hypothalamus, and amygdala
Appendix 3: The prefrontal cortex and cingulate cortex
Appendix 4: Anatomy of the septo hippocampal system
Appendix 5: Electrophysiology and pharmacology of the septo hippocampal system
Appendix 6: Electrical activity of the septo hippocampal system and behaviour
Appendix 7: Electrical stimulation of the septo hippocampal system, behaviour,
and sleep
Appendix 8: Behavioural effects of large septo hippocampal lesions
Appendix 9: Dissecting the septo hippocampal syndrome
Appendix 10: Ascending modulatory systems
|
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| spelling | Gray, Jeffrey Alan 1934-2004 Verfasser (DE-588)119122146 aut The neuropsychology of anxiety an enquiry into the functions of the septo-hippocampal system Jeffrey A. Gray and Neil McNaughton 2. ed. Oxford Oxford Univ. Press 2000 XVI, 424 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Oxford psychology series 33 Angst gtt Anxiété - Aspect physiologique ram Fysiologische aspecten gtt Neuropsicologia larpcal Neuropsychologie gtt Neuropsychology Psychophysiologie ram Anxiety Physiological aspects Anxiety drug therapy Hippocampus (Brain) Hippocampus physiology Psychology, Comparative Psychophysiology Septum (Brain) Angst (DE-588)4002053-8 gnd rswk-swf Psychologie (DE-588)4047704-6 gnd rswk-swf Neuropsychologie (DE-588)4135740-1 gnd rswk-swf Theorie (DE-588)4059787-8 gnd rswk-swf Angst (DE-588)4002053-8 s Neuropsychologie (DE-588)4135740-1 s DE-604 Theorie (DE-588)4059787-8 s Psychologie (DE-588)4047704-6 s 1\p DE-604 MacNaughton, Neil Verfasser aut Oxford psychology series 33 (DE-604)BV000005639 33 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009310881&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Gray, Jeffrey Alan 1934-2004 MacNaughton, Neil The neuropsychology of anxiety an enquiry into the functions of the septo-hippocampal system Oxford psychology series Angst gtt Anxiété - Aspect physiologique ram Fysiologische aspecten gtt Neuropsicologia larpcal Neuropsychologie gtt Neuropsychology Psychophysiologie ram Anxiety Physiological aspects Anxiety drug therapy Hippocampus (Brain) Hippocampus physiology Psychology, Comparative Psychophysiology Septum (Brain) Angst (DE-588)4002053-8 gnd Psychologie (DE-588)4047704-6 gnd Neuropsychologie (DE-588)4135740-1 gnd Theorie (DE-588)4059787-8 gnd |
| subject_GND | (DE-588)4002053-8 (DE-588)4047704-6 (DE-588)4135740-1 (DE-588)4059787-8 |
| title | The neuropsychology of anxiety an enquiry into the functions of the septo-hippocampal system |
| title_auth | The neuropsychology of anxiety an enquiry into the functions of the septo-hippocampal system |
| title_exact_search | The neuropsychology of anxiety an enquiry into the functions of the septo-hippocampal system |
| title_full | The neuropsychology of anxiety an enquiry into the functions of the septo-hippocampal system Jeffrey A. Gray and Neil McNaughton |
| title_fullStr | The neuropsychology of anxiety an enquiry into the functions of the septo-hippocampal system Jeffrey A. Gray and Neil McNaughton |
| title_full_unstemmed | The neuropsychology of anxiety an enquiry into the functions of the septo-hippocampal system Jeffrey A. Gray and Neil McNaughton |
| title_short | The neuropsychology of anxiety |
| title_sort | the neuropsychology of anxiety an enquiry into the functions of the septo hippocampal system |
| title_sub | an enquiry into the functions of the septo-hippocampal system |
| topic | Angst gtt Anxiété - Aspect physiologique ram Fysiologische aspecten gtt Neuropsicologia larpcal Neuropsychologie gtt Neuropsychology Psychophysiologie ram Anxiety Physiological aspects Anxiety drug therapy Hippocampus (Brain) Hippocampus physiology Psychology, Comparative Psychophysiology Septum (Brain) Angst (DE-588)4002053-8 gnd Psychologie (DE-588)4047704-6 gnd Neuropsychologie (DE-588)4135740-1 gnd Theorie (DE-588)4059787-8 gnd |
| topic_facet | Angst Anxiété - Aspect physiologique Fysiologische aspecten Neuropsicologia Neuropsychologie Neuropsychology Psychophysiologie Anxiety Physiological aspects Anxiety drug therapy Hippocampus (Brain) Hippocampus physiology Psychology, Comparative Psychophysiology Septum (Brain) Psychologie Theorie |
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