Epithelial transport and barrier function: pathomechanisms in gastrointestinal disorders
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York, NY
New York Acad. of Sciences
2000
|
| Schriftenreihe: | New York Academy of Sciences: Annals of the New York Academy of Sciences
915 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XII, 375 S. zahlr. Ill., graph. Darst. |
| ISBN: | 1573312592 1573312606 |
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| adam_text | ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Volume 915
December 2000
EPITHELIAL TRANSPORT AND
BARRIER FUNCTION
PATHOMECHANISMS IN
GASTROINTESTINAL DISORDERS
Editors
JORG DlETER SCHULZKE, MICHAEL FROMM, ERNST OTTO RlECKEN,
and Henry J. Binder
This volume is the result of a conference entitled Epithelial Transport and Barrier Func¬
tion: Pathomechanisms in Gastrointestinal Disorders, held on March 26 27, 1999 in
Berlin, Germany.
CONTENTS
Preface xi
Part I. Expression of Transporters and Regulation of Ion Transport
Expression and Function of Na+HCC 3~ Cotransporters in the Gastrointestinal
Tract. By Ursula Seidler, Heidi Rossmann, Petra Jacob, Oliver
Bachmann, Stephanie Christiani, Georg Lamprecht, and
Michael Gregor 1
Characterization and Molecular Localization of Anion Transporters in
Colonic Epithelial Cells. By Vazhaikkurichi M. Rajendran and
Henry J. Binder 15
Short Term Regulation of NHE3 by EGF and Protein Kinase C but Not
Protein Kinase A Involves Vesicle Trafficking in Epithelial Cells and
Fibroblasts. By M. Donowitz, A. Janecki, S. Akhter, M. E. Cavet,
F. Sanchez, G. Lamprecht, M. Zizak, W. L. Kwon, S. Khurana,
C. H. C. Yun, and C. M. Tse 30
Cl Dependent Na H Exchange: A Novel Colonic Crypt Transport Mecha¬
nism. By Henry J. Binder, Vazhaikkurichi M. Rajendran, and
John P. Geibel 43
Coupling between Na+, Sugar, and Water Transport across the Intestine. By
Ernest M. Wright and Donald D. F. Loo 54
Regulation of Chloride Secretion: Novel Pathways and Messengers. By
Stephen J. Keely and Kim E. Barrett 67
Neurotransmitters in Neuronal Reflexes Regulating Intestinal Secretion. By
Helen J. Cooke 77
Extended Abstracts
Three 5 Variant mRNAs of Anion Exchanger AE2 in Stomach and Intestine
of Mouse, Rabbit, and Rat. By Heidi Rossmann, Seth L. Alper,
Manuela Nader, Zhuo Wang, Michael Gregor, and Ursula
Seidler 81
Differential Regulation of ENaC by Aldosterone in Rat Early and Late Distal
Colon. By S. Amasheh, H. J. Epple, J. Mankertz, K. Detjen,
M. GOLTZ, J. D. SCHULZKE, AND M. FROMM 92
Epithelial Phosphate Transporters in Small Ruminants. By K. Huber,
C. Walter, B. Schroder, J. Biber, H. Murer, and G. Breves .... 95
Inflammatory Mediators Influencing Submucosal Secretory Reflexes. By
Thomas Frieling, Eckhard Weber, and Michael Schemann 98
Tumor Necrosis Factor—a Potentiates Ion Secretion Induced by Muscarinic
Receptor Activation in the Human Intestinal Epithelial Cell Line
HT29cl.l9A. By Judith C. J. Oprins, Helen P. Meijer, and
Jack A. Groot 102
Investigation of Motility and Secretion in Perfused Guinea Pig Colon ex Situ.
By Detlef Wermelskirchen and Kerstin Schneider 107
Stimulation by Portal Insulin of Intestinal Glucose Absorption via Hepatoen
teral Nerves and Prostaglandin E2 in the Isolated, Jointly Perfused Small
Intestine and Liver of the Rat. By Frank Stumpel, Bettina
SCHOLTKA, AND KURT JUNGERMANN Ill
Effects of HTV Protease Inhibitors on Barrier Function in the Human Intestinal
Cell Line HT 29/B6. By H. Bode, W. Schmidt, J.D. Schulzke,
M. Fromm, E.O. Riecken, and R. Ullrich 117
Induction of Endothelial Barrier Function in Vitro. By G. Koch, S. Pratzel,
M. Rode, and B.M. Kraling 123
Part II. Structure and Regulation of the Intestinal Barrier
The Structure and Function of Claudins, Cell Adhesion Molecules at Tight
Junctions. By Shoichiro Tsukita and Mikio Furuse 129
Intestinal Cell Adhesion Molecules: Liver Intestine Cadherin. By Reinhard
Gessner and Rudolf Tauber 136
Molecular Diversity of Plaques of Epithelial Adhering Junctions. By
Carola M. Borrmann, Claudia Mertens, Ansgar Schmidt,
Lutz Langbein, Caecilia Kuhn, and Werner W. Franke 144
Neutrophil Migration across Intestinal Epithelium. By David L. Jaye and
Charles A. Parkos 151
Expression and Function of Death Receptors and Their Natural Ligands in the
Intestine. By JORN StrAter AND PETER MOLLER 162
Role of M Cells in Intestinal Barrier Function. By T. Kucharzik,
N. LlIGERING, K. RAUTENBERG, A. L0GERING, M.A. SCHMIDT,
R. Stoll, and W. Domschke 171
Part III. Models for Studying Disturbed Transport and
Barrier Properties
Nutrient Transporter Function Studied in Heterologous Expression Systems.
By Hannelore Daniel 184
Epithelial Barrier Defects in HT 29/B6 Colonic Cell Monolayers Induced
by Tumor Necrosis Factor a. By Alfred H. Gitter,
Kerstin Bendfeldt, Heinz Schmitz, Jorg Dieter Schulzke,
Carl J. Bentzel, and Michael Fromm 193
Enhanced Expression of iNOS in Inflamed Colons of IL 2 Deficient Mice
Does Not Impair Colonic Epithelial Barrier Function. By M. Harren,
C. Barmeyer, H. Schmitz, M. Fromm, I. Horak, A. Dignass,
M. John, B. Wiedenmann, and J. D. Schulzke 204
Regulation of Intercellular Tight Junctions by Zonula Occludens Toxin and Its
Eukaryotic Analogue Zonulin. By Alessio Fasano 214
Analysis of Low Molecular Weight GTP Binding Proteins in Two Function¬
ally Different Intestinal Epithelial Cell Lines. By JURGEN STEIN,
Ruth Bauske, and Ralf Gerhard 223
Increased Tight Junction Permeability Can Result from Protein Kinase C
Activation/Translocation and Act as a Tumor Promotional Event in
Epithelial Cancers. By James M. Mullin, Kathleen V. Laughlin,
Nicole Ginanni, Colleen W. Marano, Hilary M. Clarke, and
Alejandro Peralta Soler 231
Stress Induced Decrease of the Intestinal Barrier Function: The Role of
Muscarinic Receptor Activation. By Jack Groot, Pieter Bijlsma,
Annette van Kalkeren, Amanda Kiliaan, Paul Saunders, and
Mary Perdue 237
Immunologically Mediated Transport of Ions and Macromolecules. By Linda
C. H. Yu and Mary H. Perdue 247
Extended Abstracts
Carbachol Induced Ca2+ Entry into Rat Colonic Epithelium. By
G. SCHULTHEISS, M. FRINGS, AND M. DlENER 260
Effects of Endotoxin on Human Large Intestine. By Sabine Buhner,
Bastian Mayr, Hagen Bode, Heinz Schmitz, Jorg Dieter
Schulzke, Michael Fromm, and Herbert Lochs 264
Increased Paracellular Macromolecular Transport and Subnormal Glucose
Uptake in Duodenal Biopsies of Patients with Microvillus Inclusion
Disease: Comparisons to Other Chronic Diarrhea Patients and to Non
diarrhea Patients. By P. B. Bijlsma, A. J. Kiliaan, G. Scholten,
A. van der Wal, M. Heyman, H. S. A. Heymans, J. A. Groot, and
J. A. J. M. Taminiau 267
Apoptosis and Intestinal Barrier Function. By CHRISTIAN BOJARSKI,
Kerstin Bendfeldt, Alfred H. Gitter, Joachim Mankertz,
Michael Fromm, Siegfried Wagner, Ernst Otto Riecken, and
jorg dleter schulzke 270
p53 Independent Apoptosis Induced by Menadione in the Human Colon
Carcinoma Cell Line Caco 2. By J. M. Karczewski, J. A. M. Vet,
D. Hessels, and J. Noordhoek 275
Epidermal Growth Factor, Polyamines, and Epithelial Remodeling in Caco 2
Cells. By Vladan Milovic, Ruth B auske, Lyudmila Turchanowa,
AND JURGEN STEIN 279
Effect of TNFot and IFNy on Epithelial Barrier Function in Rat Rectum in
Vitro. By Ingo Grotjohann, Heinz Schmitz, Michael Fromm,
AND JORG DlETER SCHULZKE 282
Colectomy and Heal Pouch: Transport and Barrier in Pouchitis. By
A. J. Kroesen, M. Stockmann, J. D. Schulzke, M. Fromm, and
H. J. Buhr 287
Part IV. Diarrheal Mechanisms in Gastrointestinal Diseases
Mechanisms of Epithelial Barrier Impairment in HIV Infection. By MARTIN
Stockmann, Heinz Schmitz, Michael Fromm, Wolfgang
Schmidt, Georg Pauli, Peter Scholz, Ernst Otto Riecken, and
jorg dleter schulzke 293
Cytokine Induced Alteration of the Epithelial Barrier to Food Antigens in
Disease. By M. Heyman and J. F. Desjeux 304
Epithelial Barrier and Transport Function of the Colon in Ulcerative Colitis.
By H. Schmitz, C. Barmeyer, A. H. Gitter, F. Wullstein,
C. J. Bentzel, M. Fromm, E. O. Riecken, and J. D. Schulzke 312
Diarrhea in Ulcerative Colitis: The Role of Altered Colonic Sodium
Transport. By Emma Greig and Geoffrey I. Sandle 327
Barrier Dysfunction and Crohn s Disease. By Jon Meddings 333
Mechanisms of Cholera Toxin Induced Diarrhea. By E. Beubler and
R. Schuligoi 339
Effects of Clostridium difficile Toxins on Epithelial Cell Barrier. By
Charalabos Pothoulakis 347
Ion Transport during Growth and Differentiation. By
J. Venkatasubramanian, J. Sahi, and M. C. Rao 357
Index of Contributors 373
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| id | DE-604.BV013624217 |
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| indexdate | 2024-07-09T18:49:08Z |
| institution | BVB |
| isbn | 1573312592 1573312606 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-009306913 |
| oclc_num | 45162192 |
| open_access_boolean | |
| owner | DE-20 DE-12 DE-188 |
| owner_facet | DE-20 DE-12 DE-188 |
| physical | XII, 375 S. zahlr. Ill., graph. Darst. |
| publishDate | 2000 |
| publishDateSearch | 2000 |
| publishDateSort | 2000 |
| publisher | New York Acad. of Sciences |
| record_format | marc |
| series | New York Academy of Sciences: Annals of the New York Academy of Sciences |
| series2 | New York Academy of Sciences: Annals of the New York Academy of Sciences |
| spelling | Epithelial transport and barrier function pathomechanisms in gastrointestinal disorders ed. by Jörg-Dieter Schulzke ... New York, NY New York Acad. of Sciences 2000 XII, 375 S. zahlr. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier New York Academy of Sciences: Annals of the New York Academy of Sciences 915 Digestive System cabt Digestive Disorders cabt Biological Transport cabt Epithelium cabt Conferences cabt Biologisch transport gtt Darmwand gtt Epithélium - Congrès Jonctions serrées (Biologie cellulaire) - Congrès Maagdarmziekten gtt Pathologie moléculaire - Congrès Tractus gastro-intestinal - Muqueuse - Congrès Tractus gastro-intestinal - Physiopathologie - Congrès Transport biologique - Congrès Biological Transport physiology Congresses Biological transport Congresses Digestive System physiopathology Congresses Epithelium Congresses Gastrointestinal Diseases physiopathology Congresses Gastrointestinal mucosa Congresses Gastrointestinal system Pathophysiology Congresses Molecular Biology Congresses Pathology, Molecular Congresses Tight Junctions Congresses Tight junctions (Cell biology) Congresses Stofftransport Biologie (DE-588)4443397-9 gnd rswk-swf Gastrointestinaltrakt (DE-588)4074445-0 gnd rswk-swf Darmepithel (DE-588)4220708-3 gnd rswk-swf Epithel (DE-588)4130937-6 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1999 Berlin gnd-content Epithel (DE-588)4130937-6 s Gastrointestinaltrakt (DE-588)4074445-0 s DE-604 Darmepithel (DE-588)4220708-3 s Stofftransport Biologie (DE-588)4443397-9 s Schulzke, Jörg-Dieter Sonstige oth New York Academy of Sciences: Annals of the New York Academy of Sciences 915 (DE-604)BV002532608 915 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009306913&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Epithelial transport and barrier function pathomechanisms in gastrointestinal disorders New York Academy of Sciences: Annals of the New York Academy of Sciences Digestive System cabt Digestive Disorders cabt Biological Transport cabt Epithelium cabt Conferences cabt Biologisch transport gtt Darmwand gtt Epithélium - Congrès Jonctions serrées (Biologie cellulaire) - Congrès Maagdarmziekten gtt Pathologie moléculaire - Congrès Tractus gastro-intestinal - Muqueuse - Congrès Tractus gastro-intestinal - Physiopathologie - Congrès Transport biologique - Congrès Biological Transport physiology Congresses Biological transport Congresses Digestive System physiopathology Congresses Epithelium Congresses Gastrointestinal Diseases physiopathology Congresses Gastrointestinal mucosa Congresses Gastrointestinal system Pathophysiology Congresses Molecular Biology Congresses Pathology, Molecular Congresses Tight Junctions Congresses Tight junctions (Cell biology) Congresses Stofftransport Biologie (DE-588)4443397-9 gnd Gastrointestinaltrakt (DE-588)4074445-0 gnd Darmepithel (DE-588)4220708-3 gnd Epithel (DE-588)4130937-6 gnd |
| subject_GND | (DE-588)4443397-9 (DE-588)4074445-0 (DE-588)4220708-3 (DE-588)4130937-6 (DE-588)1071861417 |
| title | Epithelial transport and barrier function pathomechanisms in gastrointestinal disorders |
| title_auth | Epithelial transport and barrier function pathomechanisms in gastrointestinal disorders |
| title_exact_search | Epithelial transport and barrier function pathomechanisms in gastrointestinal disorders |
| title_full | Epithelial transport and barrier function pathomechanisms in gastrointestinal disorders ed. by Jörg-Dieter Schulzke ... |
| title_fullStr | Epithelial transport and barrier function pathomechanisms in gastrointestinal disorders ed. by Jörg-Dieter Schulzke ... |
| title_full_unstemmed | Epithelial transport and barrier function pathomechanisms in gastrointestinal disorders ed. by Jörg-Dieter Schulzke ... |
| title_short | Epithelial transport and barrier function |
| title_sort | epithelial transport and barrier function pathomechanisms in gastrointestinal disorders |
| title_sub | pathomechanisms in gastrointestinal disorders |
| topic | Digestive System cabt Digestive Disorders cabt Biological Transport cabt Epithelium cabt Conferences cabt Biologisch transport gtt Darmwand gtt Epithélium - Congrès Jonctions serrées (Biologie cellulaire) - Congrès Maagdarmziekten gtt Pathologie moléculaire - Congrès Tractus gastro-intestinal - Muqueuse - Congrès Tractus gastro-intestinal - Physiopathologie - Congrès Transport biologique - Congrès Biological Transport physiology Congresses Biological transport Congresses Digestive System physiopathology Congresses Epithelium Congresses Gastrointestinal Diseases physiopathology Congresses Gastrointestinal mucosa Congresses Gastrointestinal system Pathophysiology Congresses Molecular Biology Congresses Pathology, Molecular Congresses Tight Junctions Congresses Tight junctions (Cell biology) Congresses Stofftransport Biologie (DE-588)4443397-9 gnd Gastrointestinaltrakt (DE-588)4074445-0 gnd Darmepithel (DE-588)4220708-3 gnd Epithel (DE-588)4130937-6 gnd |
| topic_facet | Digestive System Digestive Disorders Biological Transport Epithelium Conferences Biologisch transport Darmwand Epithélium - Congrès Jonctions serrées (Biologie cellulaire) - Congrès Maagdarmziekten Pathologie moléculaire - Congrès Tractus gastro-intestinal - Muqueuse - Congrès Tractus gastro-intestinal - Physiopathologie - Congrès Transport biologique - Congrès Biological Transport physiology Congresses Biological transport Congresses Digestive System physiopathology Congresses Epithelium Congresses Gastrointestinal Diseases physiopathology Congresses Gastrointestinal mucosa Congresses Gastrointestinal system Pathophysiology Congresses Molecular Biology Congresses Pathology, Molecular Congresses Tight Junctions Congresses Tight junctions (Cell biology) Congresses Stofftransport Biologie Gastrointestinaltrakt Darmepithel Epithel Konferenzschrift 1999 Berlin |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009306913&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV002532608 |
| work_keys_str_mv | AT schulzkejorgdieter epithelialtransportandbarrierfunctionpathomechanismsingastrointestinaldisorders |