Principles of renal physiology:
Saved in:
| Main Author: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Dordrecht [u.a.]
Kluwer
2000
|
| Edition: | 4. ed. |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | X, 203 S. Ill., graph. Darst. |
| ISBN: | 0792361784 0792360745 |
Staff View
MARC
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Record in the Search Index
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| adam_text | Contents
Preface ix
Terminology and abbreviations x
1 The body fluids 1
1.1 Introduction 1
1.2 Body water 2
1.3 Body fluid osmolality 2
1.4 Distribution of ions across biological membranes 6
1.5 Fluid exchanges between body compartments 8
1.6 Fluid exchanges between the body and the external
environment 11
1.7 Ionic composition of the body fluids 12
1.8 Ion exchanges between the body and the external
environment 13
1.9 Body fluid compartments: methods of measurement 14
Further reading 19
Problems 19
2 Essential anatomy of the kidney 20
2.1 Introduction 20
2.2 General morphology and cellular organization 20
2.3 Blood supply and vascular structure within the kidney 27
2.4 Renal lymphatic drainage 29
2.5 Juxtaglomerular apparatus 29
Further reading 33
3 Glomeralar filtration 34
3.1 The filter 34
3.2 Glomerular filtration process 37
3.3 Composition of the glomerular filtrate 43
3.4 Filtration fraction 44
3.5 Tubulo glomerular feedback 44
Further reading 45
Problems 46
v
vi Contents
4 Tubular transport 47
4.1 Introduction 47
4.2 Primary and secondary active transport 47
4.3 Ion channels, uniporters and facilitated diffusion 50
4.4 Paracellular movement 51
4.5 Water absorption 51
4.6 Fractional excretion and fractional reabsorption 52
Further reading 52
5 The proximal tubule 53
5.1 Morphology of proximal tubule cells 53
5.2 Proximal tubular handling of sodium 53
5.3 Uptake of NaCl and water into peritubular capillaries 57
5.4 Relationship of proximal tubular reabsorption to
glomerular filtration rate 58
5.5 Proximal tubular reabsorption of other solutes 58
5.6 Secretory processes in the proximal tubule 66
Further reading 68
Problem 69
6 The loop of Henle, distal tubule and collecting duct 70
6.1 The loop of Henle 70
6.2 Collecting tubules 76
6.3 Importance of urea in countercurrent multiplication 76
6.4 Further requirements of the countercurrent multiplication
mechanism: the vasa recta 78
6.5 Long and short loops of Henle 79
6.6 Regulation of urine concentration 80
6.7 Other hormones affecting distal nephron transport processes 84
Further reading 84
7 Renal blood flow and glomerular filtration rate 86
7.1 Measurement of renal blood flow and
glomerular filtration rate 86
7.2 Regulation of renal blood flow and glomerular filtration rate 92
Further reading 94
Problem 95
8 Regulation of body fluid osmolality 96
8.1 Introduction 96
8.2 Osmoreceptors 97
8.3 Regulation of water excretion and water reabsorption 102
Further reading 107
Contents vii
9 Regulation of body fluid volume 108
9.1 Introduction 108
9.2 Aldosterone 109
9.3 Renin and angiotensin, and their relationship to aldosterone 111
9.4 Starling forces and proximal tubular sodium reabsorption 114
9.5 Renal nerves 116
9.6 Prostaglandins and other arachidonate metabolites 116
9.7 Atrial natriuretic peptide and urodilatin 117
9.8 Other factors which may be involved in
regulating sodium excretion 118
9.9 ADH and the relationship between osmotic
regulation and volume regulation 120
9.10 Overall scheme of body fluid volume regulation 121
Further reading 122
10 Renal regulation of body fluid pH 124
10.1 Introduction 124
10.2 Physiological buffers 124
10.3 Renal regulation of plasma bicarbonate concentration 127
10.4 Regulation of H+ secretion according to
acid base balance requirements 134
Further reading 142
Problem 142
11 Renal control of body fluid potassium content 143
11.1 Importance of K+in the body 143
11.2 Regulation of body K+ 144
11.3 Hypokalaemia 146
11.4 Hyperkalaemia 148
Further reading 149
12 Renal regulation of body calcium, magnesium and phosphate 150
12.1 Introduction 150
12.2 Calcium 150
12.3 Phosphate 153
12.4 Calcium and phosphate homeostasis 154
12.5 Magnesium 157
Further reading 160
13 Summary of the principal reabsorptive and secretory processes
in the nephron segments 161
13.1 Introduction 161
13.2 Sodium 161
viii Contents
13.3 Water 161
13.4 Potassium 163
13.5 Hydrogen ions and HCO3 163
13.6 Phosphate 164
13.7 Calcium 164
13.8 Glucose 164
13.9 Urea and other nitrogenous waste products 164
14 Disease conditions which alter renal sodium
and water reabsorption 166
14.1 Introduction 166
14.2 Oedema 166
14.3 Congestive heart failure 168
14.4 Hypovolaemia and shock 170
14.5 Hypertension 176
14.6 Liver disease 179
14.7 Nephrotic syndrome 181
Further reading 182
15 Use of diuretics 183
15.1 Introduction 183
15.2 Osmotic diuretics 183
15.3 Loop diuretics 184
15.4 Thiazides 185
15.5 Aldosterone antagonists 185
15.6 Na channel blockers 186
15.7 Carbonic anhydrase inhibitors 186
15.8 Clinical use of diuretics 186
Further reading 188
Answers to problems 189
Index 193
|
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| dewey-tens | 610 - Medicine and health |
| discipline | Biologie Medizin |
| edition | 4. ed. |
| format | Book |
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| id | DE-604.BV013441579 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:45:59Z |
| institution | BVB |
| isbn | 0792361784 0792360745 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-009174520 |
| oclc_num | 46678755 |
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| physical | X, 203 S. Ill., graph. Darst. |
| publishDate | 2000 |
| publishDateSearch | 2000 |
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| publisher | Kluwer |
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| spelling | Lote, Christopher J. Verfasser (DE-588)142940194 aut Principles of renal physiology Chris Lote 4. ed. Dordrecht [u.a.] Kluwer 2000 X, 203 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Kidney physiology Examination Questions Kidneys Physiology Renal Circulation physiology Examination Questions Niere (DE-588)4042270-7 gnd rswk-swf Physiologie (DE-588)4045981-0 gnd rswk-swf Niere (DE-588)4042270-7 s Physiologie (DE-588)4045981-0 s DE-604 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009174520&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Lote, Christopher J. Principles of renal physiology Kidney physiology Examination Questions Kidneys Physiology Renal Circulation physiology Examination Questions Niere (DE-588)4042270-7 gnd Physiologie (DE-588)4045981-0 gnd |
| subject_GND | (DE-588)4042270-7 (DE-588)4045981-0 |
| title | Principles of renal physiology |
| title_auth | Principles of renal physiology |
| title_exact_search | Principles of renal physiology |
| title_full | Principles of renal physiology Chris Lote |
| title_fullStr | Principles of renal physiology Chris Lote |
| title_full_unstemmed | Principles of renal physiology Chris Lote |
| title_short | Principles of renal physiology |
| title_sort | principles of renal physiology |
| topic | Kidney physiology Examination Questions Kidneys Physiology Renal Circulation physiology Examination Questions Niere (DE-588)4042270-7 gnd Physiologie (DE-588)4045981-0 gnd |
| topic_facet | Kidney physiology Examination Questions Kidneys Physiology Renal Circulation physiology Examination Questions Niere Physiologie |
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