Surgical adhesives and sealants: current technology and applications
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Lancaster [u.a.]
Technomic Publ.
1996
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XX, 247 S. Ill., graph. Darst. |
| ISBN: | 1566763274 |
Staff View
MARC
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| 020 | |a 1566763274 |9 1-56676-327-4 | ||
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| 245 | 1 | 0 | |a Surgical adhesives and sealants |b current technology and applications |c ed. by David H. Sierra ... |
| 264 | 1 | |a Lancaster [u.a.] |b Technomic Publ. |c 1996 | |
| 300 | |a XX, 247 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 650 | 7 | |a Pansements et bandages |2 ram | |
| 650 | 4 | |a Adhesives in surgery | |
| 650 | 4 | |a Fibrin Tissue Adhesive | |
| 650 | 4 | |a Surgical Procedures, Operative | |
| 650 | 4 | |a Tissue Adhesives | |
| 700 | 1 | |a Sierra, David H. |e Sonstige |4 oth | |
| 856 | 4 | 2 | |m HBZ Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009156206&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-009156206 | ||
Record in the Search Index
| _version_ | 1804128205144064000 |
|---|---|
| adam_text | CONTENTS
Preface xv
Contributing Authors xvii
SECTION I ADHESIVE TECHNOLOGIES
Chapter 1: History of Tissue Adhesives 3
W. D. SPOTNITZ
Introduction 3
The Ideal Adhesive 3
Cyanoacrylate 4
Fibrin Sealant 4
Gelatin Resorcinol Formol (GRF) Glue 6
Mussel Adhesive Protein Prolamine Gel and Transforming
Growth Factor Beta (TGF /3) 7
Conclusion 7
References 8
Chapter 2: Commercial Pooled Source Fibrin Sealant 13
M.J. MacPHEE
Introduction 13
Production Issues 14
Product Safety 15
Application of Fibrin Sealants 16
Availability of Commercial Products 16
Conclusion 17
References 18
vii
viii Contents
Chapter 3: Mussel Adhesive Protein 19
K. GREEN
Introduction 19
Materials and Methods 19
Results 21
Discussion 24
Acknowledgements 26
References 26
Chapter 4: Fibrin Collagen Composite Tissue Adhesive 29
D. H. SIERRA
Introduction 29
Materials and Methods 30
Effect of Collagen Preparation on Gelation (Thrombin) lime 30
Concentrations and Gelation Time Effects in Vitro 32
Viscosity ofFibrinogen, Collagen and Composite Solutions;
Prepolymerized 34
Viscoelastic Mechanical Properties 35
Dissolution Onset Time 38
Conclusion 38
References 39
Chapter 5: Soldering Is a Superior Alternative to
Fibrin Sealant 41
L. S. BASS, S. K. LIBUTTI, M. L. KAYTON,
R. NOWYGROD and M. R. TREAT
Introduction 41
Materials and Methods 42
Laser System 42
Preparation of Adhesives/Solders 42
Animal Model 43
Analysis 43
Results 43
Discussion 44
References 45
SECTION II LABORATORY EVALUATION
Chapter 6: Kinetic and Mechanical Parameters
of Fibrin Glue 49
G. MARX
Introduction 49
Contents ix
Mechanism of Gel Formation 49
Kinetics of Gelation 50
Mechanical Properties 53
Viscoelasticity 53
Breaking Strength 54
Conclusion 58
Acknowledgement 58
References 59
Chapter 7: Surgical Tissue Adhesives: Host Tissue
Response, Adhesive Strength and Clinical Performance 61
D. TORIUMI
Introduction 61
Host Tissue Response to Adhesives 61
Biomechanical Testing of Adhesives 63
Clinical Efficacy 68
Final Comments 69
References 69
Chapter 8: Biological and Rheological Properties of a
Virally Inactivated Fibrin Glue (Biocol®): Comparison to
an Autologous Fibrin Glue 71
M. BURNOUF RADOSEVICH, P. DUVAL,
B. FLAN, P. APPOURCHAUX, C. MICHALSKI,
T. BURNOUFandJ. J. HUART
Introduction 71
Fibrin Glue Production 72
Biochemical and Biological Properties 73
Rheological Properties 73
Viral Safety and Validation 76
Clinical Applications 77
Regulatory Aspects 77
Conclusions 77
References 78
Chapter 9: Assessment of Restored Tissue Elasticity in
Prolonged in vivo Animal Tissue Healing: Comparing
Fibrin Sealant to Suturing 79
J. F. LONTZ, J. M. VERDERAMO, J. CAMAC, I. ARIKAN,
D. ARIKAN and G. M. LEMOLE
Introduction 79
Restored Biomechanical Tissue Integrity 81
x Contents
Materials and Methods 83
Fibrin Sealant Preparations 83
Fibrin Sealant Application 83
In vivo Animal Tissue Sealant Closures 84
Tensile Constants Measurements and Assessment 84
Results and Discussion 87
Tensile Testing Results 87
Tensile Break Strength 87
Tensile Strength 88
Tensile Elongation 88
References 90
Chapter 10: Veterinary Hemaseer9: Ex vivo and in vivo
Studies on Bovine Fibrin Sealant 91
T. BRODNIEWICZ, T. BUI KHAC, P. EMIRE,
K. RUDNICKA and M. NOWOTARSKI
Introduction 91
Animal Safety Studies 91
Acute Topical Haemostasis Studies 92
Formulation 92
Animal Model 92
In vivo Studies of Wound Sealing and Healing 93
Preparation 93
Animal Model 93
Ex vivo Studies 95
Conclusion 96
Reference 96
SECTION III LABORATORY APPLICATIONS
Chapter 11: Wound Healing Applications of
Fibrin Sealants 99
D. FELDMAN
Introduction 99
Biocompatibility Hierarchy 100
Ramifications in Implant Design: Fibrin Sealants 103
References 107
Chapter 12: Fibrin Sealant: A Versatile Delivery Vehicle
for Drugs and Biologies 109
M. J. MacPHEE, M. P. SINGH, R. BRADY, JR., N. AKHYANI,
G. LIAU, C. LASA, JR., C. HUE, A. BEST and W. DROHAN
Introduction 109
Contents xi
Antibiotic Delivery from Fibrin Sealant 110
Delivery of Chemotherapeutics from Fibrin Sealant 112
Fibrin Sealant as a Delivery Vehicle for Osteoinducers 114
Delivery of Fibroblast Growth Factors from Fibrin Sealant 115
Delivery of Tributyrin from Fibrin Sealant 117
Conclusions 119
References 119
Chapter 13: Sustained Release of Antibiotics from
Fibrin Sealant 121
M. P. SINGH, R. BRADY, JR., W. DROHAN and M. J. MacPHEE
Introduction 121
Materials and Methods 123
Fibrin Sealant 123
Tetracycline Supplemented Fibrin Sealant 123
Tetracycline Release in Vitro 124
Measurement of Tetracycline Concentrations 124
Linear Regression 124
Results 124
Kinetics of Release ofTETfrom TET FS 124
Discussion 128
References 132
Chapter 14: Bone Induction by Demineralized Bone
Powder and Partially Purified Osteogenin Using a
Fibrin Sealant Carrier 135
C. LASA,JR.,J. HOLLINGER, W. DROHAN and M.J. MacPHEE
Introduction 135
Materials and Methods 136
Fibrin Sealant (FS) 136
Implant Preparation; DBF Study 136
Implant Preparation; Osteogenin Study 137
Animals 138
Surgery 138
Retrieval of Implants 138
Radiography 139
Radiomorphometry 139
Statistical Analysis 139
Histological Analysis 139
Results 139
Histology of Implants 140
Discussion 142
xii Contents
Conclusion 142
References 143
Chapter 15: Fibrin Sealant as a Delivery Vehicle
for Sustained and Controlled Release of
Chemotherapy Agents 145
M. J. MacPHEE, A. CAMPAGNA, A. BEST, R. KIDD and W. DROHAN
Introduction 145
Materials and Methods 147
Reagents 147
Preparation ofFS + 5 FU Clots 147
Determination of 5 FU Release Kinetics 147
Statistics 148
Results 148
Duration of Delivery of 5 FU from FS Is Extended by the Use
of the Anhydrous Form 148
Duration of Delivery of 5 FU from FS Is Proportional to the
Mass of Anhydrous 5 FU 148
The Rate of Delivery of 5 FU from FS Is Constant under
Limited Sink Conditions 149
The Rate of Delivery of 5 FU from FS Is Constant under
Infinite Sink Conditions 149
Discussion 150
Conclusions 152
Acknowledgements 152
References 152
Chapter 16: Experimental and Clinical Considerations:
Craniofacial Surgery and Bone Metabolism 155
H. C. VASCONEZ andj. B. RODGERS
References 159
SECTION IV CLINICAL APPLICATIONS AND INVESTIGATIONS
Chapter 17: Fibrin Sealant and the U.S. Food and Drug
Administration Review Process 163
W. A. FRICKE
Introduction 163
Investigational New Drugs 164
Product License Application 167
Fibrin Sealant 168
Conclusion 172
References 172
Contents xiii
Chapter 18: Utilization of Fibrin Glue in Craniofacial and
Facial Plastic Surgery 173
D. MARCHAC
The Use of Sprayed Fibrin Glue in Facelifts 173
Use of Fibrin Glue in Craniofacial Surgery 175
References 176
Chapter 19: Tissue Adhesives in Plastic and
Reconstructive Surgery 177
H. N. HIMEL
Introduction 177
Aery late Adhesives 177
Fibrin Sealant 179
References 183
Chapter 20: Clinical Applications of Tissue Adhesives in
Aesthetic and Reconstructive Surgery 187
R. SALTZ
Introduction 187
Functional and Aesthetic Reconstruction of Burned Hands 187
Aesthetic Reconstruction of Facial Burns 188
Grafting Wounds at Difficult Sites 194
Tissue Adhesives and Aesthetic Surgery 198
Tissue Adhesives and Endoscopic Surgery 200
Acknowledgement 202
References 202
Chapter 21: Surgical Adhesives in Otolaryngology 205
K. H. SIEDENTOP
Summary 218
References 219
Chapter 22: A Review of Nonsuture Peripheral
Nerve Repair 221
j. k. terzis
Introduction 221
Fibrin Glue 221
Historical Review 221
Composition of Fibrin Glues 222
Experimental Studies 223
Clinical Studies 225
Cyanoacrylates 225
xiv Contents
Laser Welding of Nerves 227
Experimental Studies 22 7
Cell Surgery in Nerve Repair 229
The Future 229
References 230
Chapter 23: Clinical Use of Fibrin Based Composite
Tissue Adhesive in Otology and Neurotology 233
R. C. PERKINS and D. H. SIERRA
Introduction 233
Clinical Trials 233
Patients 234
Investigational Materials 234
Neurotologic Procedures 235
Otologic Procedures 235
Evaluation Procedure 235
Clinical Results 236
Conclusions 236
Acknowledgements 237
References 237
Chapter 24: Clinical Applications of Fibrin Sealant in
Thoracic and Cardiovascular Surgery 239
W. D. SPOTNITZ
Introduction 239
University of Virginia System 239
Methods of Application 240
TCV Uses of Fibrin Sealant 240
Recent Innovations 241
Complications 241
Conclusion 242
References 242
Index 245
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| physical | XX, 247 S. Ill., graph. Darst. |
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| spelling | Surgical adhesives and sealants current technology and applications ed. by David H. Sierra ... Lancaster [u.a.] Technomic Publ. 1996 XX, 247 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Pansements et bandages ram Adhesives in surgery Fibrin Tissue Adhesive Surgical Procedures, Operative Tissue Adhesives Sierra, David H. Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009156206&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Surgical adhesives and sealants current technology and applications Pansements et bandages ram Adhesives in surgery Fibrin Tissue Adhesive Surgical Procedures, Operative Tissue Adhesives |
| title | Surgical adhesives and sealants current technology and applications |
| title_auth | Surgical adhesives and sealants current technology and applications |
| title_exact_search | Surgical adhesives and sealants current technology and applications |
| title_full | Surgical adhesives and sealants current technology and applications ed. by David H. Sierra ... |
| title_fullStr | Surgical adhesives and sealants current technology and applications ed. by David H. Sierra ... |
| title_full_unstemmed | Surgical adhesives and sealants current technology and applications ed. by David H. Sierra ... |
| title_short | Surgical adhesives and sealants |
| title_sort | surgical adhesives and sealants current technology and applications |
| title_sub | current technology and applications |
| topic | Pansements et bandages ram Adhesives in surgery Fibrin Tissue Adhesive Surgical Procedures, Operative Tissue Adhesives |
| topic_facet | Pansements et bandages Adhesives in surgery Fibrin Tissue Adhesive Surgical Procedures, Operative Tissue Adhesives |
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