Real time analysis of biomolecular interactions: applications of BIACORE
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English Japanese |
| Veröffentlicht: |
Tokyo [u.a.]
Springer
2000
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturangaben |
| Beschreibung: | X, 256 S. Ill., graph. Darst. |
| ISBN: | 443170289X |
Internformat
MARC
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| 245 | 1 | 0 | |a Real time analysis of biomolecular interactions |b applications of BIACORE |c K. Nagata ... (ed.) |
| 246 | 1 | 3 | |a Real-time analysis of biomolecular interactions |
| 264 | 1 | |a Tokyo [u.a.] |b Springer |c 2000 | |
| 300 | |a X, 256 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 500 | |a Literaturangaben | ||
| 650 | 4 | |a Biomolecules | |
| 650 | 4 | |a Chemical kinetics | |
| 650 | 4 | |a Ligands | |
| 650 | 4 | |a Physical biochemistry | |
| 650 | 4 | |a Surface Plasmon Resonance |x methods | |
| 650 | 0 | 7 | |a Biospecific interaction analysis |0 (DE-588)4605359-1 |2 gnd |9 rswk-swf |
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| 700 | 1 | |a Nagata, Kazuhiro |e Sonstige |4 oth | |
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| 999 | |a oai:aleph.bib-bvb.de:BVB01-009118243 | ||
Datensatz im Suchindex
| _version_ | 1804128146398642176 |
|---|---|
| adam_text | K Nagata, H Handa (Eds )
Real-Time Analysis of
Biomolecular Interactions
Applications of BIACORE
With 122 Figures, Including 2 in Color
Springer
Contents
Preface v
Part 1: Introduction
1 Significance of the Real-Time Analysis of Biological Interactions
KAZUHIRO NAGATA 3
1 1 Introduction 3
1 2 Commonly Used Methods for Detecting the Interactions
Between Two Molecules 4
1 3 Surface Plasmon Resonance:
A Useful Principle for the Analysis of Molecular Interaction 6
1 4 Real-Time Analysis Reveals the Importance of the Transient Interaction
of Molecular Chaperones with Their Substrates 7
Part 2: General Principles
1 Principles of Surface Plasmon Resonance
FRANCIS MARKEY 13
1 1 The SPR Phenomenon 13
1 2 Conditions for Resonance - 16
1 3 SPR as a Refractometer 18
1 4 Conditions Affecting SPR 19
1 5 Physical Arrangements for SPR Measurement 20
1 6 SPR-Based Biosensors : : 21
2 Principles of BIACORE
SETSUKO HASHIMOTO 23
2 1 Introduction 23
2 2 What is BIACORE? 23
2 3 The Sensor Chip : 24
2 4 Optical Measurement Principle 26
2 5 Liquid Handling System 27
2 6 The Sensorgram 29
^ H Development of BIACORE ^^^ • • • • ^^^^^^^ • • ^^^H
MAGNUS MALMQVIST 31
viii • • Contents
Part 3: Basic Procedures
1 Experimental Procedures
JUNICHI INAGAWA, ISSEY OKAZAKI, KAORI MORIMOTO,
AND SETSUKO HASHIMOTO 35
1 1 Introduction 35
1 2 Preparation of Sample and Buffer 35 i
1 3 Immobilizing Ligand 38
1 4 Sensor Chips 42
1 5 Analyzing Molecular Interaction 48
2 Data Analysis Methods 59
2 1 General Methods
TOHRU NATSUME AND FRANCIS MARKEY 59
2 2 Kinetic Analysis of Response Curve of BIACORE Data with
Nonlinear Least Squares Regression Method
HIROYUKI YASUI 71
Part 4: Applications
1 Protein-Protein Interactions 87
1 1 Molecular Chaperones
NORIYUKI MURAI AND MASASUKE YOSHIDA 8 7
1 2 DNA Polymerase d Complex
TOSHIKI TSURIMOTO 95
1 3 The Analysis of Protein-Protein Interactions in Early Development:
Direct Binding of Fpllistatin, an Organizer Factor, to BMPs
SHUN-ICHIROIEMURA, TAKAMASA YAMAMOTO, CHIYOTAKAGI,
ANDNAOTOUENO 105
2 Peptide-Protein Interactions 115
2 1 Physical Measurements of the Interaction of MHC Molecules and
T-Cell Receptors
MARIE T JELONEK, KANNAN NATARAJAN,
AND DAVID H MARGULIES 115
3 DNA-Protein Interactions 127
3 1 Transcription Factors
JUN-ICHI SAWADA AND FUMIHIKO SUZUKI 127
Contents ix
3 2 Anti UV-damaged DNA Antibodie
HlROSHI MORIOKA, HlROYUKI KOBAYASHI, AND ElKO OHTSUKA 133
4 DNA-DNA Interactions 141
4 1 Mismatch Detection by Hybridization :
MASANORI GOTOH AND MARIKO TOSU 141
5 Sugar-Protein Interactions 147
5 1 Carbohydrate-Lectin Interaction
YASURO SHINOHARA 147
5 2 Protein-Carbohydrate Interactions on Liposomes
ROGER MACKENZIE AND TOMOKO HIRAMA 154
6 Lipid-Protein Interactions 163
6 1 Blood Coagulation Proteins
MORIOARAI 163
7 Applications for Purification and Screening 173
7 1 Identification and Purification of Ligand for Receptor
Protein-Tyrosine Kinase
SEIJI SAKANO AND TOSHIO SUDA 173
7 2 Screening for Low Molecular Weight Substances of Microbial Origin
Acting on the Inositol 1,4,5-Trisphosphate Receptor
KAZUO SHIN-YA AND HARUO SETO 180
7 3 Phage Display Method
ANN-CHRISTIN MALMBORG 187
8 Clinical Applications 195
8 1 The Application of BIA Technology in the Optimization of Humanized
Mouse Anti-Parathyroid Hormone-Related Protein(PTHrP) Antibodies
KEIKOESAKI 195
8 2 Epitope Mapping of Human Myeloperoxidase
PHILIP T CHAPMAN 201
9 Combinations with Other Methods 207
9 1 Comparison with Calorimetry and Stopped-Flow
YOSHIKAZU KUROSAWA 207
x Contents
9 2 With Mass Spectrometry
CHRISTOPHER WILLIAMS 214
9 3 NMR Analysis for Interactions Between Bio-Macromolecules
ICHIO SHIMADA 223
9 4 Analytical Ultracentrifugation
FUMIO ARISAKA 232
Part 5: View for the Future
1 • View for the Future
HIROSHI HANDA 245
1 1 Introduction 245
1 2 Requirements for Further Development of BIACORE 246
1 3 Possible Future Applications of BIACORE in Various Fields 248
1 4 Conclusion 251
Subject Index 253
Using BIACORE as Pots and Pans
TOHRU NATSUME
1 Is Recombinant Soluble? Detection of GST Fusion Protein
Expressed mE coli 58
2 Activity of a Refolded Receptor 84
3 Optimization of Expression Conditions in E coli 114
4 Production Amount of Monoclonal Antibody 126
5 Quick Isoelectric Point Check 140
6 Establishment of Experimental Conditions for Structure Analysis 242
7 Fraction Check 252
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| isbn | 443170289X |
| language | English Japanese |
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| spelling | Real time analysis of biomolecular interactions applications of BIACORE K. Nagata ... (ed.) Real-time analysis of biomolecular interactions Tokyo [u.a.] Springer 2000 X, 256 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Literaturangaben Biomolecules Chemical kinetics Ligands Physical biochemistry Surface Plasmon Resonance methods Biospecific interaction analysis (DE-588)4605359-1 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Biospecific interaction analysis (DE-588)4605359-1 s DE-604 Nagata, Kazuhiro Sonstige oth HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009118243&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Real time analysis of biomolecular interactions applications of BIACORE Biomolecules Chemical kinetics Ligands Physical biochemistry Surface Plasmon Resonance methods Biospecific interaction analysis (DE-588)4605359-1 gnd |
| subject_GND | (DE-588)4605359-1 (DE-588)4143413-4 |
| title | Real time analysis of biomolecular interactions applications of BIACORE |
| title_alt | Real-time analysis of biomolecular interactions |
| title_auth | Real time analysis of biomolecular interactions applications of BIACORE |
| title_exact_search | Real time analysis of biomolecular interactions applications of BIACORE |
| title_full | Real time analysis of biomolecular interactions applications of BIACORE K. Nagata ... (ed.) |
| title_fullStr | Real time analysis of biomolecular interactions applications of BIACORE K. Nagata ... (ed.) |
| title_full_unstemmed | Real time analysis of biomolecular interactions applications of BIACORE K. Nagata ... (ed.) |
| title_short | Real time analysis of biomolecular interactions |
| title_sort | real time analysis of biomolecular interactions applications of biacore |
| title_sub | applications of BIACORE |
| topic | Biomolecules Chemical kinetics Ligands Physical biochemistry Surface Plasmon Resonance methods Biospecific interaction analysis (DE-588)4605359-1 gnd |
| topic_facet | Biomolecules Chemical kinetics Ligands Physical biochemistry Surface Plasmon Resonance methods Biospecific interaction analysis Aufsatzsammlung |
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