Exocyclic DNA adducts in mutagenesis and carcinogenesis:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Lyon
International Agency for Research on Cancer
1999
|
| Schriftenreihe: | International Agency for Research on Cancer: IARC scientific publications
150 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XVI, 361 S. |
| ISBN: | 9283221508 |
Internformat
MARC
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Datensatz im Suchindex
| _version_ | 1804128123677048832 |
|---|---|
| adam_text | Contents
Contributors viii
Foreword xiv
Acknowledgements xv
Abbreviations xvi
Keynote address: 1
Exocyclic adducts as new risk markers for DNA damage in man
H. Bartsch
Chapter I. Occurrence and methods of detection 17
Chemistry and biology of DNA damage by malondialdehyde
LJ. Marnett
Formation and repair of DNA adducts in vinyl chloride and vinyl 29
fluoride induced carcinogenesis
J.A. Swenberg, M. Bogdanffy, A. Ham, S. Holt, A. Kim,
E.J. Morinello, A. Ranasinghe, N. Scheller P. Upton
Role of 1 ,/V2 propanodeoxyguanosine adducts as endogenous 45
DNA lesions in rodents and humans
F. L Chung, L Zhang, J.E. Ocando R.G. Nath
Lipid peroxidation induced etheno DNA adducts in humans 55
J. Nair
Detection of 1,A/6 etheno 2 deoxyadenosine and 3,W4 etheno 2 63
deoxycytidine occurring endogenously in DNA
W.P. Watson, J.P. Aston, T. Barlow, A.E. Crane, D. Potter
T. Brown
Chapter II. Chemistry 75
Possible mechanisms of carcinogenesis after exposure
to benzene
B.T. Golding W.P. Watson
Synthesis of para benzoquinone and 1,3 bis(2 chloroethyl) 89
nitrosourea adducts and their incorporation into oligonucleotides
A. Chenna, H. Maruenda B. Singer
Purine DNA adducts of 4,5 dioxovaleric acid and 2,4 decadienal 103
J. Cadet, V.M. Carvalho, J. Onuki, T. Douki, M.H.G.
Medeiros P. Di Mascio
v
Exocyclic DNA Adducts in Mutagenesis and Carcinogenesis
Adducts of chlorohydroxyfuranones and of aldehyde conjugates 115
L Kronberg, T. Munter, J. Maki, F. Le Curieux, D.
Pluskota R. Sjoholm
Cyclic adducts and intermediates induced by simple epoxides 123
J.J. Solomon
Chapter III. Formation from exogenous and endogenous sources 137
Formation of etheno adducts and their effects on DNA polymerases
F.P. Guengerich, S. Langouet, AM Mican, S. Akasaka,
M. Muller M. Persmark
Reactions of cc acetoxy A/ nitrosopyrrolidine and crotonaldehyde 147
with DNA
S.S. Hecht, P. Upadhyaya M. Wang
Glyoxal guanine DNA adducts: Detection, stability and formation in 155
vivo from nitrosamines
R.N. Loeppky, W. Cui, P. Goelzer Q. Ye
Chapter IV. Physiochemical approaches to structural elucidation 169
Effects of 3,W4 etheno deoxycytidine on duplex stability and
energetics
G.E. Plum, C.A. Gelfand K.J. Breslauer
Solution structures of DNA duplexes containing the exocyclic lesion 179
3, A/4 etheno 2 deoxycytidine
D. Cullinan, M. Eisenberg C. de los Santos
Thermal destabilization of DNA oligonucleotide duplexes by 191
exocyclic adducts on adenine or cytosine depends on both the
base and the size of the adduct
J. Sagi B. Singer
Chapter V. Cyclic adducts as biomarkers 197
A sensitive immunoslot blot assay for detection of malondialde
hyde deoxyguanosine in human DNA
C. Leuratti, R. Singh, E.J. Deag, E. Griech, R. Hughes,
S.A. Bingham, IP. Plastaras, LJ. Marnett D.E.G. Shuker
32P Postlabelling with high performance liquid chromatography for 205
analysis of abundant DNA adducts in human tissues
K. Yang, J. L Fang, D. Li, F. L Chung K. Hemminki
vi
__^ Contents
Cancer risk assessment for crotonaldehyde and 2 hexenal: An 219
approach
E. Eder, D. Schuler Budiawan
Chapter VI. DNA repair and effects on replication 233
Mammalian enzymatic repair of etheno and para benzoquinone
exocyclic adducts derived from the carcinogens vinyl chloride and
benzene
B. Singer B. Hang
Enzymology of the repair of etheno adducts in mammalian cells 249
and in Escherichia coli
M. Saparbaev J. Laval
Cellular response to exocyclic DNA adducts 263
M. Moriya, G.A. Pandya, F. Johnson A.P. Grollman
Role of base excision repair in protecting cells from the toxicity of 271
chloroethylnitrosoureas
D.B. Ludlum, Q. Li Z. Matijasevic
Localization of chloroacetaldehyde induced DNA damage in human 279
p53 gene by DNA polymerase fingerprint analysis
B. Tudek, P. Kowalczyk J.M. Cieula
Chapter VII. Mutagenesis and carcinogenesis 295
Cancer prone oxyradical overload disease
S. Ambs, S.P. Hussain, A.J. Marrogi C.C. Harris
Role of etheno DNA adducts in carcinogenesis induced by vinyl 303
chloride in rats
A. Barbin
Vinyl chloride specific mutations in humans and animals 315
M.J. Marion S. Boivin Angele
Solution conformation and mutagenic specificity of 1 ,A/6 ethenoadenine 325
A.K. Basu, J.M. McNulty W.G. McGregor
Genetic effects of exocyclic DNA adducts in vivo: Heritable genetic 335
damage in comparison with loss of heterozygosity in somatic cells
M.J.M. Nivard E.W. Vogel
Appendix. Distortion of the double helix by para benzoquinone adducts 351
J. Sagi B. Singer
Subject index 357
vii
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| language | English |
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| publishDate | 1999 |
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| series2 | International Agency for Research on Cancer: IARC scientific publications |
| spelling | Exocyclic DNA adducts in mutagenesis and carcinogenesis ed. by B. Singer ... Lyon International Agency for Research on Cancer 1999 XVI, 361 S. txt rdacontent n rdamedia nc rdacarrier International Agency for Research on Cancer: IARC scientific publications 150 Addukt (DE-588)4141390-8 gnd rswk-swf Carcinogenese (DE-588)4069853-1 gnd rswk-swf DNS (DE-588)4070512-2 gnd rswk-swf Mutagenese (DE-588)4170881-7 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content DNS (DE-588)4070512-2 s Addukt (DE-588)4141390-8 s Carcinogenese (DE-588)4069853-1 s DE-604 Mutagenese (DE-588)4170881-7 s Singer, Beatrice 1922- Sonstige (DE-588)121656810 oth International Agency for Research on Cancer: IARC scientific publications 150 (DE-604)BV000002423 150 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009103251&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Exocyclic DNA adducts in mutagenesis and carcinogenesis International Agency for Research on Cancer: IARC scientific publications Addukt (DE-588)4141390-8 gnd Carcinogenese (DE-588)4069853-1 gnd DNS (DE-588)4070512-2 gnd Mutagenese (DE-588)4170881-7 gnd |
| subject_GND | (DE-588)4141390-8 (DE-588)4069853-1 (DE-588)4070512-2 (DE-588)4170881-7 (DE-588)4143413-4 |
| title | Exocyclic DNA adducts in mutagenesis and carcinogenesis |
| title_auth | Exocyclic DNA adducts in mutagenesis and carcinogenesis |
| title_exact_search | Exocyclic DNA adducts in mutagenesis and carcinogenesis |
| title_full | Exocyclic DNA adducts in mutagenesis and carcinogenesis ed. by B. Singer ... |
| title_fullStr | Exocyclic DNA adducts in mutagenesis and carcinogenesis ed. by B. Singer ... |
| title_full_unstemmed | Exocyclic DNA adducts in mutagenesis and carcinogenesis ed. by B. Singer ... |
| title_short | Exocyclic DNA adducts in mutagenesis and carcinogenesis |
| title_sort | exocyclic dna adducts in mutagenesis and carcinogenesis |
| topic | Addukt (DE-588)4141390-8 gnd Carcinogenese (DE-588)4069853-1 gnd DNS (DE-588)4070512-2 gnd Mutagenese (DE-588)4170881-7 gnd |
| topic_facet | Addukt Carcinogenese DNS Mutagenese Aufsatzsammlung |
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