Biomembrane transport:
Saved in:
| Main Author: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
San Diego [u.a.]
Acad. Press
1999
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| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XIV, 397 S. Ill., graph. Darst. |
| ISBN: | 0127145109 |
Staff View
MARC
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| 245 | 1 | 0 | |a Biomembrane transport |c Lon J. Van Winkle |
| 264 | 1 | |a San Diego [u.a.] |b Acad. Press |c 1999 | |
| 300 | |a XIV, 397 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
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| 650 | 7 | |a Biologisch transport |2 gtt | |
| 650 | 4 | |a Carrier proteins | |
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| 650 | 4 | |a Biological Transport |x physiology | |
| 650 | 4 | |a Biological transport | |
| 650 | 4 | |a Carrier Proteins |x metabolism | |
| 650 | 4 | |a Cell membranes | |
| 650 | 4 | |a Membranes (Biology) | |
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Record in the Search Index
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| adam_text | Foreword xi
Preface xiii
1. Importance of Biomembrane Transport
I. Introduction 1
II. Solute and Solvent Fluxes Are Determined by
Barriers and Propelling Forces 3
III. Biomembrane Transport in Context 7
IV. Summary 10
2. Biomembrane Composition, Structure,
and Turnover
I. Introduction 13
II. Is the Fluid Mosaic Model of Membrane
Structure Still Adequate? 13
III. Some Components of the Biomembrane Can
Be Reconstituted 29
IV. How Are Biomembrane Composition and
Structure Regulated? 30
V. Summary 38
3. Thermodynamics and Transport
I. Introduction 39
II. Similar Mathematical Expressions Serve for
the Free Energy Change in a Chemical
Reaction and in the Migration of a Solute or
Solvent 39
III. Changes in Enthalpy and Entropy May
Contribute Differently to the Free Energy
Changes Associated with a Biochemical
Reaction and Migration of a Solute 43
IV. The Total Chemical Potential Change for a
Transport Process Also May Have an
Electrical Component 44
V. The Gibbs Donnan Effect Also Generates
Osmotic Pressure 47
VI. Chemical Reactions Drive Primary Active
Transport 49
VII. Reversal of Transport May Drive Chemical
Reactions 55
VIII. How Do Fluctuations in the Local Hydrogen
Ion Potential Facilitate Formation of
Phosphoric Acid Anhydride Bonds by the
Mitochondrial FoF^ATP Synthase? 56
IX. Conversion of Solute Total Chemical Potential
Gradients to Gradients of Other Solutes during
Co and Countertransport 57
X. Dissipation of Solute Gradients through
Mediated Transport Processes May Also
Perform Work 61
XI. Application of Thermodynamic Principles to
the Solution of Practical Transport
Problems 63
XII. Summary 63
4. Transport Kinetics
I. Introduction 65
II. Kinetics of Diffusion 66
III. How Do Measurements of both the Diffusional
and the Osmotic Permeability Coefficient for
Water Inform Us about the Mechanism of
Water Transport across a Plasma
Membrane? 70
IV. Do Lipophilic Substances Migrate across
Biomembrane Phospholipid Bilayers by Simple
Diffusion? 73
V. Lipid Soluble Substances Are Used to
Attempt to Measure the Width of Unstirred
Water Layers on Either Side of
Biomembranes 74
VI. Do Such Determinations of the Apparent
Widths of Unstirred Water Layers Reflect the
Intended Physical Phenomenon or Our
Ignorance of How Lipid Soluble Substances
Cross Biomembranes? 76
VII. Protein versus Lipid Mediated Mechanisms of
Fatty Acid Migration across
Biomembranes 79
VIII. Protein Mediated Biomembrane Transport Is
Probably Always Substrate Saturable 81
IX. Kinetics of Saturable Transport 83
X. Identification and Minimization or Deduction
of Processes That May Obscure a Transport
Process of Interest 98
XI. Kinetic Differences among Substrate Saturable
Transport Processes That Form, Propagate, or
Dissipate Solute Gradients 116
XII. Summary 124
Appendix 126
5. Structure and Function of Transport
Proteins That Form Solute Gradients
I. Introduction 133
II. P Type ATPases 135
III. FOF! ATP Synthases (F Type ATPases) 152
IV. Summary 166
6. Transport Proteins That Propagate
Solute Gradients
I. Introduction to Symporters and
Antiporters 169
II. Both Erythroid and Nonerythroid Tissues
Express Anion Exchangers 170
III. ASC and Excitatory (Anionic) Amino Acid
Transporters Comprise One of Two Known
Families of Mammalian Na+/Amino Acid
Symporters 208
IV. Both AE and EAAT/ASC Proteins Have
Additional Functions 233
V. Summary 237
7. Channel Proteins Usually Dissipate
Solute Gradients
I. Introduction 239
II. Structure, Function, and Evolution of Channel
Proteins 240
III. Kinetics of Transport via K* and Other
Channels 254
IV. Summary 262
8. A Proposed System for the Classification
of Transmembrane Transport Proteins in
Living Organisms
I. Introduction 265
II. Work of the Enzyme Commission as a Basis for
the Systematic Classification of Transport
Proteins 265
III. Phylogeny as a Basis for Protein Classification:
Criteria for Family Assignment 266
IV. Proposed Transport Protein Classification
System 267
V. Representative Examples of Classified
Families 272
VI. Cross Classification of Transport Proteins 272
VII. The Two Largest Superfamilies of Transporters:
The MF and ABC Superfamilies 275
VIII. Macromolecular Transport Proteins in
Bacteria 275
IX. Conclusions and Perspectives 276
9. Regulation of Plasma Membrane Transport
I. Introduction 277
II. Regulation of Transport by Changes in Driving
Force: The Role of Plasma Membrane
Potential 277
III. Regulation of the Activity of Existing
Transporters through Modifications of
Transporter Molecules 278
IV. Regulation of Transport by Changes in the
Repertoire of Transport Proteins in the Plasma
Membrane 284
V. Coordinated Regulation of Transport
Systems 287
VI. Derangements in Transport Regulation 287
VII. Summary 293
10. Biomembrane Transport and Interorgan
Nutrient Flows: The Amino Acids
I. Interorgan Nutrition 295
II. Interorgan Amino Acid Nutrition: General
Principles and Key Issues 295
III. Control of Interorgan Amino Acid Metabolism:
Metabolic Control Theory and Safety
Factors 308
IV. Physiologically Important Flows of Amino
Acids and Related Compounds 311
V. Amino Acid Nutrition under Special
Circumstances 319
VI. Summary 325
11. Selected Techniques in Membrane
Transport
I. Introduction 327
II. Purification and Reconstitution of Transport
Proteins 327
III. Methods for Isolating cDNAs Coding for
Transport Proteins 328
IV. Heterologous Expression Systems for Transport
Proteins 329
V. Voltage Clamp Techniques in Xenopus
Oocytes 332
VI. Probing Transport with Ion Selective
Microelectrodes 338
VII. Optical Methods for Measuring Membrane
Transport 339
VIII. Structure Function Studies of Transport
Proteins 339
IX. Genetic Approaches to Understanding
Transporter Function 341
X. Summary of Preparations Used to Study Native
Membrane Transport 341
XI. Commentary
Epilogue 343
References 345
Index 387
|
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| dewey-tens | 570 - Biology |
| discipline | Biologie |
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| id | DE-604.BV013294777 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:43:15Z |
| institution | BVB |
| isbn | 0127145109 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-009062843 |
| oclc_num | 41158404 |
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| owner | DE-355 DE-BY-UBR DE-526 DE-11 |
| owner_facet | DE-355 DE-BY-UBR DE-526 DE-11 |
| physical | XIV, 397 S. Ill., graph. Darst. |
| publishDate | 1999 |
| publishDateSearch | 1999 |
| publishDateSort | 1999 |
| publisher | Acad. Press |
| record_format | marc |
| spelling | Van Winkle, Lon J. Verfasser (DE-588)1067905111 aut Biomembrane transport Lon J. Van Winkle San Diego [u.a.] Acad. Press 1999 XIV, 397 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Biologisch transport gtt Carrier proteins Membranen gtt Biological Transport physiology Biological transport Carrier Proteins metabolism Cell membranes Membranes (Biology) Membranes physiology Biomolekül (DE-588)4135124-1 gnd rswk-swf Membrantransport (DE-588)4038575-9 gnd rswk-swf Membrantransport (DE-588)4038575-9 s Biomolekül (DE-588)4135124-1 s DE-604 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009062843&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Van Winkle, Lon J. Biomembrane transport Biologisch transport gtt Carrier proteins Membranen gtt Biological Transport physiology Biological transport Carrier Proteins metabolism Cell membranes Membranes (Biology) Membranes physiology Biomolekül (DE-588)4135124-1 gnd Membrantransport (DE-588)4038575-9 gnd |
| subject_GND | (DE-588)4135124-1 (DE-588)4038575-9 |
| title | Biomembrane transport |
| title_auth | Biomembrane transport |
| title_exact_search | Biomembrane transport |
| title_full | Biomembrane transport Lon J. Van Winkle |
| title_fullStr | Biomembrane transport Lon J. Van Winkle |
| title_full_unstemmed | Biomembrane transport Lon J. Van Winkle |
| title_short | Biomembrane transport |
| title_sort | biomembrane transport |
| topic | Biologisch transport gtt Carrier proteins Membranen gtt Biological Transport physiology Biological transport Carrier Proteins metabolism Cell membranes Membranes (Biology) Membranes physiology Biomolekül (DE-588)4135124-1 gnd Membrantransport (DE-588)4038575-9 gnd |
| topic_facet | Biologisch transport Carrier proteins Membranen Biological Transport physiology Biological transport Carrier Proteins metabolism Cell membranes Membranes (Biology) Membranes physiology Biomolekül Membrantransport |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009062843&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT vanwinklelonj biomembranetransport |