Molecular mechanisms of smooth muscle contraction:
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Austin, Tex.
Landes
1999
|
| Series: | Molecular biology intelligence unit
5 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | 165 S. Ill., graph. Darst. |
| ISBN: | 1570595666 |
Staff View
MARC
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| 245 | 1 | 0 | |a Molecular mechanisms of smooth muscle contraction |c Kazuhiro Kohama ... |
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| 300 | |a 165 S. |b Ill., graph. Darst. | ||
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| 490 | 1 | |a Molecular biology intelligence unit |v 5 | |
| 650 | 2 | |a Actines | |
| 650 | 2 | |a Contraction musculaire | |
| 650 | 2 | |a Muscles lisses | |
| 650 | 7 | |a Myosine |2 ram | |
| 650 | 4 | |a Actin | |
| 650 | 4 | |a Actins | |
| 650 | 4 | |a Muscle Contraction |x physiology | |
| 650 | 4 | |a Muscle contraction | |
| 650 | 4 | |a Muscle, Smooth |x physiology | |
| 650 | 4 | |a Myosin | |
| 650 | 4 | |a Myosin-Light-Chain Kinase | |
| 650 | 4 | |a Myosins | |
| 650 | 4 | |a Signal Transduction | |
| 650 | 4 | |a Smooth muscle |x Molecular aspects | |
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Record in the Search Index
| _version_ | 1804127744873725952 |
|---|---|
| adam_text | 1. Smooth Muscle Myosin as Revealed
by Baculovirus Sf9 Cell Expression System 1
Shin ichiro Kojima and Hirofumi Onishi
Genetic Systems for Mutagenesis 2
Outlines of Smooth Muscle Myosin 2
Mutations of Active Site 6
Mutations of the Actin Binding Face 8
Swinging of Lever Arm 10
Conclusion 11
2. The Molecular Anatomy of Myosin Light Chain Kinase 15
Kohichi Hayakawa, Hiroko Kishi, Kazuhiro Kohama, Yuan Lin, Akio
Nakamura, Tsuyoshi Okagaki, Yinhuan Xue, and Li Hong Ye
Characterization of MLCK as an Actin Binding Protein 16
Regulation of Actin Myosin Interaction
by the Actin Binding of MLCK 18
Effects of Other Smooth Muscle Actin Binding Proteins
on Actin Myosin Interaction 21
Physiological Involvement of the Inhibitory Effect of MLCK
in Regulating the Actin Myosin Interaction
of Smooth Muscle Cells 22
Myosin Binding Properties of MLCK 23
Conclusion 25
3. Structure and Regulatory Mechanisms of Myosin Phosphatase 31
David J. Hartshorne, Kazuhito Ichikawa, Masaaki ho, and Takeshi
Nakano
Structural Components of Smooth Muscle Myosin
Phosphatase 32
Regulatory Mechanisms of MP Activity 38
Possible Function of MP 41
Conclusion 42
4. Regulation of Smooth Muscle Myosin Phosphatase
and Contraction by Rho and Rho Kinase 47
Yoh Takuwa
Downregulation of Myosin Phosphatase and Consequent Sensitization
of MLC20 Phosphorylation 49
Involvement of the Low Molecular Weight G Protein
Rho in the Downregulation of Myosin Phosphatase
and in Ca Sensitization 50
Rho Kinase Mediates Rho Dependent Downregulation
of Myosin Phosphatase 50
Conclusion 53
5. Caldesmon Phosphorylation and Smooth Muscle Contraction 59
Nikolai B. Gusev,Vladimir P. Shirinsky, and Alexander V. Vorotnikov
Caldesmon Gene, mRNA and Protein 59
Domain Structure and Activities 60
Caldesmon s Place and Role in Smooth Muscle 62
Caldesmon Phosphorylation In Vitro 67
Phosphorylation of Caldesmon in Smooth Muscle Tissues 70
The Complex Case of In Vivo Caldesmon Kinase 73
Future Prospects 74
6. Thick and Thin Filament Regulation of Smooth Muscle
Contraction in Health and Disease 81
William E. Butler, InKyeom Kim, and Kathleen G. Morgan
Regulation of Smooth Muscle Contraction in Health 81
Regulation of Smooth Muscle Contraction in Disease 85
Conclusion 92
7. Diphosphorylation of Myosin Light Chain and Spastic
Contraction of Smooth Muscle 97
Y. Sasaki and M. Seto
Quantification Method of MLC20 Phosphorylation 98
Diphosphorylation of MLC20 in Intact Smooth Muscle 100
Mechanism for the Formation of MLC20
Diphosphorylation in Smooth Muscle 101
Diphosphorylation of MLC20 in Spastic Smooth Muscle 103
Conclusion 104
8. Intracellular Mechanisms
for Coronary Artery Spasm 107
Hiroaki Shimokawa
Endothelial Dysfunction vs. Smooth Muscle
Hypercontraction 107
Animal Models of Coronary Artery Spasm 108
Mechanisms of Vascular Smooth Muscle Contraction 110
Coronary Artery Spasm and Vascular Smooth Muscle 110
Enhanced Myosin Light Phosphorylations
and Coronary Spasm Ill
Future Directions of Research on the Pathogenesis
of Coronary Artery Spasm 113
9. Antispastic Therapeutic, HA1077 (Eril) 119
H. Hidaka, Y. Sasaki, and M. Shibuya
Pharmacological Properties 119
Biochemical Property 120
Attenuation of Spastic Contraction 124
Clinical Trial: Prospective Placebo Controlled
Double Blind Study on a Delayed Cerebral
Vasospasm After SAH 126
10. Molecular Mechanisms of Smooth Muscle
Phenotypic Modulation 133
Masahiko Kurabayashi and Ryozo Nagai
Technical Comments 134
Isolation of Genomic Clones and Sequence Analysis 137
Reporter Gene Analysis of the 5 Flanking Region
of the SMemb Gene 137
Nuclear Factor Binding to the Sequence
Between 105 and 91 138
Isolation of Rabbit BTEB2 cDNA 138
Transactivation of SMemb Promoter by BTEB2 139
Expression of the BTEB2 mRNA in Adult Tissues
and Developing Aorta 139
BTEB2 Expression in Neointimal SMCs 139
Conclusion 139
11. Migration and Proliferation of Smooth Muscle Cells
for Arterial Intimal Growth 143
/. Jiang, M. Mitsumata,Q. Shu, and Yoji Yoshida
Phenotypes of Vascular Smooth Muscle Cells 145
Growth Factors and Biologically Active Substances
Expressed by SMC Particularly Related to Migration 147
Migration of Medial SMC to the Intima 150
Proliferation of SMC and Extracellular Matrix
in the Vessel Wall 152
Effects of Inhibitors Against Angiotensin Converting
Enzyme (ACE) on Neointimal Growth After Balloon
Injury 155
Matrix Metalloproteinases of the Vessel Wall 155
Elastase of the Vessel Wall 157
Human and Animal Arteries Have Preferential Areas
for Atherosclerosis 157
Index 163
|
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| dewey-full | 612.7/41 |
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| dewey-ones | 612 - Human physiology |
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| dewey-search | 612.7/41 |
| dewey-sort | 3612.7 241 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Book |
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| id | DE-604.BV013047085 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:38:13Z |
| institution | BVB |
| isbn | 1570595666 |
| language | English |
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| physical | 165 S. Ill., graph. Darst. |
| publishDate | 1999 |
| publishDateSearch | 1999 |
| publishDateSort | 1999 |
| publisher | Landes |
| record_format | marc |
| series | Molecular biology intelligence unit |
| series2 | Molecular biology intelligence unit |
| spelling | Molecular mechanisms of smooth muscle contraction Kazuhiro Kohama ... Austin, Tex. Landes 1999 165 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Molecular biology intelligence unit 5 Actines Contraction musculaire Muscles lisses Myosine ram Actin Actins Muscle Contraction physiology Muscle contraction Muscle, Smooth physiology Myosin Myosin-Light-Chain Kinase Myosins Signal Transduction Smooth muscle Molecular aspects Muskelkontraktion (DE-588)4170858-1 gnd rswk-swf Glatte Muskulatur (DE-588)4157472-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Glatte Muskulatur (DE-588)4157472-2 s Muskelkontraktion (DE-588)4170858-1 s DE-604 Kohama, Kazuhiro Sonstige oth Molecular biology intelligence unit 5 (DE-604)BV012379718 5 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008889392&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Molecular mechanisms of smooth muscle contraction Molecular biology intelligence unit Actines Contraction musculaire Muscles lisses Myosine ram Actin Actins Muscle Contraction physiology Muscle contraction Muscle, Smooth physiology Myosin Myosin-Light-Chain Kinase Myosins Signal Transduction Smooth muscle Molecular aspects Muskelkontraktion (DE-588)4170858-1 gnd Glatte Muskulatur (DE-588)4157472-2 gnd |
| subject_GND | (DE-588)4170858-1 (DE-588)4157472-2 (DE-588)4143413-4 |
| title | Molecular mechanisms of smooth muscle contraction |
| title_auth | Molecular mechanisms of smooth muscle contraction |
| title_exact_search | Molecular mechanisms of smooth muscle contraction |
| title_full | Molecular mechanisms of smooth muscle contraction Kazuhiro Kohama ... |
| title_fullStr | Molecular mechanisms of smooth muscle contraction Kazuhiro Kohama ... |
| title_full_unstemmed | Molecular mechanisms of smooth muscle contraction Kazuhiro Kohama ... |
| title_short | Molecular mechanisms of smooth muscle contraction |
| title_sort | molecular mechanisms of smooth muscle contraction |
| topic | Actines Contraction musculaire Muscles lisses Myosine ram Actin Actins Muscle Contraction physiology Muscle contraction Muscle, Smooth physiology Myosin Myosin-Light-Chain Kinase Myosins Signal Transduction Smooth muscle Molecular aspects Muskelkontraktion (DE-588)4170858-1 gnd Glatte Muskulatur (DE-588)4157472-2 gnd |
| topic_facet | Actines Contraction musculaire Muscles lisses Myosine Actin Actins Muscle Contraction physiology Muscle contraction Muscle, Smooth physiology Myosin Myosin-Light-Chain Kinase Myosins Signal Transduction Smooth muscle Molecular aspects Muskelkontraktion Glatte Muskulatur Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008889392&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV012379718 |
| work_keys_str_mv | AT kohamakazuhiro molecularmechanismsofsmoothmusclecontraction |