Drugs in anaesthetic and intensive care practice:
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Oxford [u.a.]
Butterworth-Heinemann
1999
|
| Edition: | 8. ed. |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | 7. Aufl. u.d.T.: Vickers, Michael D.: Drugs in anaesthetic practice |
| Physical Description: | XX, 526 S. graph. Darst. |
| ISBN: | 0750637277 |
Staff View
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| 245 | 1 | 0 | |a Drugs in anaesthetic and intensive care practice |c M. D. Vickers ... |
| 250 | |a 8. ed. | ||
| 264 | 1 | |a Oxford [u.a.] |b Butterworth-Heinemann |c 1999 | |
| 300 | |a XX, 526 S. |b graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
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| 500 | |a 7. Aufl. u.d.T.: Vickers, Michael D.: Drugs in anaesthetic practice | ||
| 650 | 7 | |a Anesthesie |2 gtt | |
| 650 | 7 | |a Geneesmiddelen |2 gtt | |
| 650 | 7 | |a Intensive care |2 gtt | |
| 650 | 4 | |a Pharmacology | |
| 650 | 4 | |a Adjuvants, Anesthesia | |
| 650 | 4 | |a Anesthesia adjuvants | |
| 650 | 4 | |a Anesthetics | |
| 650 | 4 | |a Critical care medicine | |
| 650 | 4 | |a Intensive Care | |
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Record in the Search Index
| _version_ | 1804127450973601792 |
|---|---|
| adam_text | Contents
Preface to the eighth edition xvii
Preface to the first edition xix
1 General pharmacology 1
Mechanisms of action of drugs 2
Concept of a receptor 4
Characterization and classification of receptors 5
Receptor types and subtypes 12
G Protein coupled receptors 14
Drug interactions 16
Transfer of drugs across membranes 20
Physical properties affecting transfer 21
Transfer across special membranes 23
Routes of drug administration 23
Factors affecting drug dosage 27
Timing of administration 28
Binding of drugs 29
Distribution of drugs in the body 30
Drug metabolism 30
Drug excretion 33
Factors determining biophase concentration 34
Compartment models 36
Drug elimination 38
Pharmacokinetic compartment models 39
Pharmacokinetics of inhalation anaesthetics 43
Bioavailability 44
First pass effect 44
Automated drug delivery systems 46
Idiosyncrasy 48
Allergic reactions (anaphylactic reactions) 48
Blood dyscrasias 50
Pharmacogenetics 50
Chemotherapeutic index 52
Approved names 52
Clinical trials 53
Legal aspects of medicines 56
References and further reading 59
«W Contents
2 Perioperative therapy 61
Anxiety 61
Unwanted autonomic responses to anaesthesia 62
Induction movements 62
Regurgitation, vomiting and pulmonary aspiration 62
Premedication in children 66
Metoclopramide 67
Omeprazole 67
Ondanstron 68
3 Central nervous system depressants 70
Narcotics, hypnotics, anxiolytic sedatives, neuroleptics and general
anaesthetics 70
Anxiolytic sedatives (minor tranquillizers) 71
Benzodiazepines 73
Other anxiolytic sedatives: chemical variants 79
Neuroleptics, major tranquillizers, anti psychotics 80
Intravenous induction agents 85
Steroids 87
Other sedatives and hypnotics 88
Forced diuresis in the treatment of drug overdosage 91
Anticonvulsants 92
Drug treatment of epilepsy 93
Alcohol 96
Alimemazine (trimeprazine) 97
Clomethiazole 97
Diazepam 98
Droperidol 100
Etomidate 101
Flumazenil 102
Fluphenazine 103
Haloperidol 104
Ketamine 104
Lorazepam 107
Methohexital 108
Midazolam 108
Propofol 111
Thiopental 115
References and further reading 119
4 General anaesthetics 120
Stages of anaesthesia 120
Surgical anaesthesia 121
Mode of action of anaesthetics 121
Uptake and distribution of inhalational agents 122
Metabolism of volatile anaesthetics 126
Evaluation of anaesthetic potency 127
Pharmacology 128
Halogenated hydrocarbon anaesthetics 132
Anaesthetic gases 132
Contents is
Desflurane 133
Enflurane 134
Ether 135
Halothane 138
Isoflurane 142
Nitrous oxide 144
Sevoflurane 147
Xenon 149
Agents mainly of historical interest 149
Chloroform 149
Cyclopropane 150
Etny/ chloride 150
Fluroxene 150
Methoxyflurane 150
Trichloroethylene 150
Vmy/ ether 151
5 Systemic analgesics 152
Pain 152
Analgesics 154
Peripherally acting analgesics 163
Treatment of migraine 169
Acetylsalicylic acid 171
Alfentanil 175
Buprenorphine 176
Codeine 177
Diamorphine 178
Diclofenac 179
Fentanyl 180
Ibuprofen 182
Indometacin 183
Morphine salts 184
Naloxone 190
Nefopam hydrochloride 192
Paracetamol 192
Pentazocine 194
Pethidine 195
Piroxicam 198
Remifentanil 199
Tramadol 201
References and further reading 202
6 Local anaesthetics 203
Mode of action 203
Chemistry 204
Classification 205
Other pharmacological actions 207
Toxic effects 209
Benzocaine 210
Bupivacaine 210
* Contents
Cocaine 212
Lidocaine 213
Prilocaine 215
Ropivacaine 216
Tetracaine 217
Other local anaesthetics 219
7 Drugs affecting mood 220
Antidepressants 220
Amoxapine 226
Lithium salts 226
Mianserin 226
Rolipram 226
Antidepressent agents and anaesthesia 227
Psychomotor stimulants 228
Psychotomimetics (hallucinogens) 230
Dopamine as a neurotransmitter in the central nervous system 231
Other CNS stimulants: analeptics 232
Amfetamine and dexamfetamine 233
Amitriptyline 234
Dosulepin 236
Doxapram 237
Fluoxetine 238
Imipramine 239
Levodopa 240
Lithium 242
Methylamfetamine 243
Modobemide 244
8 Histamine, antihistamines; drugs affecting bronchial calibre 246
Histamine 246
Antihistamines 250
Bronchoconstrictors 254
Bronchodilators 255
Mucolytic agents 256
Drugs for hay fever 256
Chlorpheniramine 257
Cimetidine 257
Cromoglicate 259
Cydizine 259
Ipratropium 261
Ranitidine 261
Salbutamol 263
Theophylline and aminophylline 264
9 Neuromuscular blocking agents 266
Physiology of neuromuscular transmission 266
Neuromuscular block 267
Pharmacokinetics of relaxants 272
Clinical use of relaxants 274
Contents xl
Abnormal reactions to relaxants 276
Muscle rigidity and spasm 278
Alcuronium 279
Atracurium 279
dsatracurium 281
Dantrolene 282
Gallamine 283
Mivacurium 284
Pancuronium 286
Rocuronium 287
Suxamethonium salts 288
Tubocurarine 291
Vecuronium 293
10 Parasympathomimetic and cholinergic agents; anticholinesterases 296
Drug action 296
Anticholinesterases 300
Myasthenia gravis 302
Edrophonium 303
Neostigmine 304
Physostigmine 306
Pyridostigmine 307
11 Parasympathetic antagonists and anticholinergic agents 309
Synthetic atropine like compounds 310
Belladonna alkaloids 310
Anti Parkinsonian drugs 311
Mydriatics 311
Atropine 312
Glycopyrrolate 314
Hyoscine 315
Other synthetic anticholinergics 316
12 Drugs used for their effects on vascular tone and cardiac contractility 317
Cardiovascular control mechanisms 317
The myocardium 320
Pressor agents and vasoconstrictors 322
Inotropic agents 325
Hypotensive agents and vasodilators 330
Ganglion blocking agents 332
Agents inhibiting norepinephrine release 333
Adrenoceptor blocking agents 333
Inhibitors of angiotensin conversion 335
Direct acting vasodilators 336
Nitric oxide donors 337
Calcium channel blockers 338
Phosphodiesterase inhibitors 341
ATP ase dependent potassium channel openers 341
Adenosine uptake inhibitors 342
Vasodilators with an unknown mechanism 342
jH Contents
Drugs affecting coronary blood vessels 342
Captopril 349
Clonidine 350
Dobutamine 352
Dopamine 353
Dopexamine 354
Ephedrine 355
Epinephrine 355
Glyceryl trinitrate 356
Guanethidine 357
Hydralazine 359
Isoprenaline salts 359
Metaraminol 361
Methoxamine 362
Methyldopa 363
Milrinone 364
Nifedipine 365
Nimodipine 366
Nitric oxide 367
Nitroprusside 367
Norepinephrine 369
Phenoxybenzamine 371
Phentolamine 372
Phenylephrine 373
Prazosin 374
Sildenafil 375
Trimetaphan 376
Verapamil 377
13 Drugs used for their effects on cardiac rhythm and rate 379
The cardiac electrical cycle 379
Cardiac arrhythmias 383
Anti arrhythmic agents 383
Digitalis glycosides 390
Chronotropic agents 391
Ade«osi/ie 392
Amiodarone 394
Atenolol 395
Digoxin 396
Disopyramide 398
Esmolol 399
Metoprolol 400
Propranolol 401
Quinidine 403
Sota/o/ 404
14 Diuretics 405
Structure of the nephron 405
The glomerular filtrate 406
Modification of the glomerular filtrate 406
Contents *HI
Action of diuretics 407
Acetazolamide 409
Furosemide 409
Mannitol 411
Spironolactone 412
Thiazides 413
Triamterene 414
15 Drugs acting on the uterus 416
Uterine muscle 416
Uterine stimulants 416
Tocolytic agents 416
Ergotnetrine 418
Oxytocin 419
Prostaglandins 420
16 Chemical transmitters and enzymes 423
Chemical transmitters 423
Autacoids 423
Prostaglandins 423
Slow reacting substance 427
5 Hydroxytryptamine 427
Angiotensin 429
Plasma kinins 430
Substance P 430
Enzymes 431
Amine oxidases 431
Carbonic anhydrase 432
Cholinesterases 433
Hyaluronidase 434
Proteinases 435
References 435
17 Hormones 436
Effects of anaesthesia 436
Pituitary gland (hypophysis) and hypothalamus 437
Adrenal cortex 437
Adrenal medulla 442
Thyroid 442
Antithyroid drugs 442
Pancreas 443
Oral hypoglycaemic drugs 450
Carbimazole 445
Chlorpropamide 446
Dexamethasone 446
Glibendamide 447
Glucagon 448
Hydrocortisone 448
Insulin 449
Metformin 450
^^ ¦. W ¦ TfTi^CTrf.
Octreotide 451
Prednisolone 451
Somatotropin 452
Thyroid hormones 453
Tolbutamide 453
Vasopressin 454
18 Anticoagulants, antithrombotic, thrombolytic and haemostatic agents 456
The normal clotting process 456
Control mechanisms 458
Sites of action of anticoagulants 458
Fibrinolysis 459
Oral anticoagulants 461
Anistreplase 463
Dextrans 464
Epoprostenol 465
Ethamsylate 466
Heparin 467
Protamine 469
Tranexamic acid 470
Warfarw 470
19 Antibiotics and other antimicrobial agents 473
History 473
General approach to the use of antibiotics 473
Mode of action of antibiotics 475
Mechanisms of antibiotic resistance 477
Hypersensitivity 478
Antimicrobial agents 478
Sulphonamides 478
p Lactam antibiotics 479
Penicillins 479
Benzylpenicillin 480
Anti staphylococcal penicillins 480
Pencillins active against Gram negative bacilli 481
Ampicillin and amoxycillin 481
Other pencillins active against Gram negative bacilli 481
Cephalosporins 481
Imipenem 483
Aztreonam 483
Aminoglycosides 484
Gentamicin 485
Macrolides 485
Erythromycin 485
Fusidic acid 486
Tetracyclines 486
Chloramphenicol 486
Quinolones 486
Ciprofloxacin 486
Glycopeptides 487
Contents
Vancomycin 487
Teicoplanin 487
Antimycobacterial agents 487
Antituberculous agents 487
Isoniazid 488
Rifampicin 488
Ethambutol 489
Pyrazinamide 489
p Aminosalicylic acid 489
Cycloserine 489
Antileprotic agents 490
Antiprotozal agents 490
Metronidazole 491
Antiviral agents 492
Interferons 492
Antiviral drags 492
Idoxuridine 492
Amantadine 493
Cytosine arabinoside 493
Adenine arabinoside 493
Acyclovir 493
Gancidovir 494
Zidovudine 494
Ribavirin 494
Antifiingal agents 495
The polyenes 495
Nystatin 495
Amphoteridn B 495
Fluocytosine 496
Imidazoles 497
Clotrimazole 497
Miconazole 497
Ketoconazole 497
Triazoles 498
Itraconazole 498
Fluconazole 498
Griseofulvin 498
Antimicrobial aerosols 499
20 Plasma substitutes 500
Oxygen carrying solutions 501
Dextran 505
Gelatins 506
Human albumin 506
Stored 508
Appendix: Changes in the names of drugs 509
/mfcc 515
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| indexdate | 2024-07-09T18:33:33Z |
| institution | BVB |
| isbn | 0750637277 |
| language | English |
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| oclc_num | 40939900 |
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| owner | DE-355 DE-BY-UBR DE-384 |
| owner_facet | DE-355 DE-BY-UBR DE-384 |
| physical | XX, 526 S. graph. Darst. |
| publishDate | 1999 |
| publishDateSearch | 1999 |
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| spelling | Drugs in anaesthetic and intensive care practice M. D. Vickers ... 8. ed. Oxford [u.a.] Butterworth-Heinemann 1999 XX, 526 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier 7. Aufl. u.d.T.: Vickers, Michael D.: Drugs in anaesthetic practice Anesthesie gtt Geneesmiddelen gtt Intensive care gtt Pharmacology Adjuvants, Anesthesia Anesthesia adjuvants Anesthetics Critical care medicine Intensive Care Anästhetikum (DE-588)4001839-8 gnd rswk-swf Anästhetikum (DE-588)4001839-8 s DE-604 Vickers, Michael D. Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008692076&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Drugs in anaesthetic and intensive care practice Anesthesie gtt Geneesmiddelen gtt Intensive care gtt Pharmacology Adjuvants, Anesthesia Anesthesia adjuvants Anesthetics Critical care medicine Intensive Care Anästhetikum (DE-588)4001839-8 gnd |
| subject_GND | (DE-588)4001839-8 |
| title | Drugs in anaesthetic and intensive care practice |
| title_auth | Drugs in anaesthetic and intensive care practice |
| title_exact_search | Drugs in anaesthetic and intensive care practice |
| title_full | Drugs in anaesthetic and intensive care practice M. D. Vickers ... |
| title_fullStr | Drugs in anaesthetic and intensive care practice M. D. Vickers ... |
| title_full_unstemmed | Drugs in anaesthetic and intensive care practice M. D. Vickers ... |
| title_short | Drugs in anaesthetic and intensive care practice |
| title_sort | drugs in anaesthetic and intensive care practice |
| topic | Anesthesie gtt Geneesmiddelen gtt Intensive care gtt Pharmacology Adjuvants, Anesthesia Anesthesia adjuvants Anesthetics Critical care medicine Intensive Care Anästhetikum (DE-588)4001839-8 gnd |
| topic_facet | Anesthesie Geneesmiddelen Intensive care Pharmacology Adjuvants, Anesthesia Anesthesia adjuvants Anesthetics Critical care medicine Intensive Care Anästhetikum |
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