Applications of radiosurgery:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Philadelphia [u.a.]
Saunders
1999
|
| Schriftenreihe: | Neurosurgery clinics of North America
10,2 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIII S., S. 157 - 394 Ill., graph. Darst. |
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Datensatz im Suchindex
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| adam_text | APPLICATIONS OF RADIOSURGERY
CONTENTS
Preface xv
Douglas Kondziolka
The Radiobiology of Radiosurgery 157
Douglas Kondziolka, L. Dade Lunsford, and John C. Flickinger
Radiosurgery is the precise and complete destruction of a chosen target
containing healthy or pathological cells, without significant concomitant or
late radiation damage to adjacent cells. This article discusses briefly the
many uses of radiobiology and considers variables in the treatment, such
as dose rate, dose homogeneity, and the issue of possible pharmacological
radioprotection for radiosurgery. Comparisons between radiosurgery and
fractionation are also made.
Imaging Changes after Radiosurgery for Vascular Malformations,
Functional Targets, and Tumors 167
Lars Kihlstrom and Bengt Karlsson
Normal brain tissue is probably the most important tissue compartment in
the brain involved in adverse radiation effects (AREs). The capabilities
of computerized tomography, magnetic resonance imaging, and positron
emission tomography in repeat examinations of a treatment outcome pro¬
vide a baseline by which to monitor the AREs in vivo and to follow their
sequential changes. This article relates the AREs seen after radiosurgery to
the dose/volume and specific tissue effects established from 30 years of
collected experience with radiosurgery at the Karolinska Hospital.
Gamma Knife Radiosurgery: Technology, Applications, and
Future Directions 181
Masaaki Yamamoto
This article provides a general overview of Gamma Knife radiosurgery,
with a brief history of the design of the unit and a review of radiosurgical
procedures. The gamma unit itself is discussed, including its different ele¬
ments and how they work. The clinical applications are then examined,
NEUROSURGERY CLINICS OF NORTH AMERICA
VOLUME 10 • NUMBER 2 • APRIL 1999 jx
such as treatment of arteriovenous malformations, acoustic schwannoma,
meningiomas, pituitary adenomas, glial tumors, and others. The article
concludes with a brief discussion of the future of Gamma Knife radiosurgery.
Linear Accelerator Radiosurgery in Brain Tumor Management 203
Kelly D. Foote, William A. Friedman, John M. Buatti, Francis J. Bova,
and Sanford A. Meeks
This article begins with a brief introduction to the concepts and techniques
of linear accelerator based stereotactic radiosurgery. The expanding role of
radiosurgery in the treatment of brain tumors is explored in depth, including
detailed discussions of the five intracranial neoplasms most frequently
treated with radiosurgery. These include both benign (i.e., vestibular
schwannoma, meningioma, pituitary adenoma) and malignant (i.e., cerebral
metastasis, malignant glioma) pathologies. For each of these, a thorough
review of published radiosurgical results is presented along with a discus¬
sion of common treatment modalities. The role of radiosurgery in the treat¬
ment of brain tumors continues to be defined, but an effort is made to
provide reasonable indications for and against radiosurgery based on the
current state of the art.
Stereotactic Proton Radiosurgery 243
Griff Harsh, Jay S. Loeffler, Allan Thornton, Alfred Smith,
Marc Bussiere, and Paul H. Chapman
The technique of stereotactic proton radiosurgery is discussed in depth in
this article. The physics of the proton beam in radiosurgery is explained,
and the different factors of beam delivery are examined. These key factors
(correspondence to shape, accuracy of delineation of volume, correspon¬
dence to volume, and accuracy of delivery vary) with each of the radiosurgi¬
cal techniques, from Gamma Knife surgery to linear accelerator therapy.
Clinical series in the use of proton radiosurgery are also presented, with
an emphasis on efficacy and uses.
Extracranial Stereotactic Radiosurgery: Applications for the Spine
and Beyond 257
Istvan Takacs and Allan J. Hamilton
The role stereotactic radiosurgery has in the management of malformations
of the spine is examined in this article. Specific problems in the application
of stereotactic radiosurgery to the spine are discussed and the three tech¬
niques for spinal stereotaxis, bone screw fixation, contour mold fixation,
and frameless stereotaxis, are reviewed.
Dose Selection in Stereotactic Radiosurgery 271
John C. Flickinger, Douglas Kondziolka, and L. Dade Lunsford
Selection of the prescription dose for radiosurgery is the final step in treat¬
ment planning. Dose selection should take into account the expectation of
treatment success (i.e., tumor control, arteriovenous malformation [AVM]
obliteration, and so forth) and complication risks at various doses. Accu¬
rately predicting complication risks for individual patients is a complex
process that is highly dependent on the radiosurgery treatment volume,
the target location, and the nature of the target tissue. Dose response data
for desired outcomes of radiosurgery are sparse and difficult to interpret
for most indications, with perhaps the exception of AVM obliteration. This
X CONTENTS
article reviews the principles governing dose selection and the evolving
body of data guiding dose selection in radiosurgery.
Stereotactic Radiosurgery for Arteriovenous Malformations 281
Bruce E. Pollock
Arteriovenous malformations (AVMs) were one of the first indications for
radiosurgery. Radiosurgery has been shown to be an important management
strategy for properly selected AVM patients. Radiosurgery is especially
useful for patients with AVMs in deep brain locations and critical lobar
areas. This article outlines the results and expectations of contemporary
AVM radiosurgery and discusses the role of radiosurgery in the manage¬
ment of patients with AVMs.
Radiosurgery of Angiographically Occult Vascular Malformations 291
Yoshihisa Kida, Tatsuya Kobayashi, and Yoshimasa Mori
Angiographically occult vascular lesions (AVOMs) are vascular lesions not
visualized on standard cerebral angiography. The possibility of managing
these difficult lesions with radiosurgery is discussed. The radiosurgical
treatments and results of AVOMs are described and the strategies for manag¬
ing AOVMs and cavernous malformations are discussed.
Can Hearing Improve After Acoustic Tumor Radiosurgery? 305
Ajay Niranjan, L. Dade Lunsford, John C. Flickinger, Ann Maitz,
and Douglas Kondziolka
Advances in noninvasive diagnostic techniques have enabled physicians to
diagnose acoustic tumors early, while hearing is still present. Applications
of advanced operative techniques have allowed surgeons to decrease pro¬
gressively the operative mortality to virtually zero, to save facial nerve
function in a large number of patients, and even to preserve serviceable
hearing in selected patients. Documented improvement in hearing after
acoustic tumor surgery is rare. During the last decade, stereotactic radiosur¬
gery has evolved as a noninvasive surgical option for acoustic tumors.
Hearing improvement after radiosurgery has not been reported. The authors
observed hearing improvement in 21 out of 487 patients who had radiosur¬
gery during a 10 year interval. This article reviews their experience of hear¬
ing improvement after radiosurgery and suggests possible reasons that
hearing can not only be retained but also improved in selected patients.
Stereotactic Radiosurgery for Meningiomas 317
Douglas Kondziolka, Ajay Niranjan, L. Dade Lunsford,
and John C. Flickinger
The indications for and results after meningioma radiosurgery results are
discussed. Particular emphasis is placed on longer term results, the evolu¬
tion of technique, complications, and recommendations regarding the role
of radiosurgery together with other management strategies.
Radiosurgery for Pituitary Tumors and Craniopharyngiomas 327
Edward R. Laws, Jr and Mary Lee Vance
Standard techniques of conventional radiation therapy have been used for
many years to treat pituitary adenomas and craniopharyngiomas. These
techniques are not always effective and carry with them morbidity in the
CONTENTS XI
form of damage to the normal pituitary gland, damage to the hypothalamus,
the potential of damage to the visual system and to intellectual functions
of the brain and a small but real risk of the development of secondary
malignancies. In an effort to avoid these complications and to provide more
effective adjunctive radiation therapy, techniques of stereotactic delivery of
high dose radiation to the pituitary region have been developed, known
as radiosurgery. The history of the development of radiosurgery and its
application to pituitary problems are recounted in this article, as are a
number of the controversies that currently exist and need to be considered
as these modalities of stereotactic radiosurgery are applied more frequently
and to better effect in the future.
Radiosurgery for Brain Metastases 337
Timothy S. Boyd and Minesh P. Mehta
Brain metastases represent the most common intracranial neoplasm, and
they have become the most common indication for radiosurgery. The au¬
thors present a review summarizing the major issues surrounding the man¬
agement of brain metastases and an English language literature review of
21 independent reports, using either Gamma Knife or linear accelerator
based radiosurgery, with over 1700 patients and more than 2700 lesions
available for analysis.
The Role of Radiosurgery for Glial Neoplasms 351
Eben Alexander III and Jay S. Loeffler
Malignant gliomas are one of the most serious challenges in clinical neuro
surgery. Despite advances in surgical and radiation techniques, chemother¬
apy, and other systemic antineoplastic regimens, such as gene therapy and
immunotherapy, patients who suffer from malignant gliomas often succumb
to their disease. Although some success has been made with forms of en¬
hanced surgical guidance and localized radiotherapy, current techniques
are unable to eradicate the infiltrative glioma cells.
Radiosurgery for Trigeminal Neuralgia and Epilepsy 359
Jean Regis, Fabrice Bartolomei, Philippe Metellus, Marc Rey,
Pierre Genton, Charlotte Dravet, Michele Bureau, Franck Semah,
Jean L. Gastaut, Jean C. Peragut, and Patrick Chauvel
The role of Gamma Knife surgery in the field of functional surgery recently
has evolved dramatically. For treatment of trigeminal neuralgia, Gamma
Knife surgery is the least invasive procedure, with a low rate of hypesthesia.
If a rate of complete relief similar to that of other surgical techniques could
be achieved, this approach will become one of the main techniques used
to treat the disease initially. The authors present their experience with a
group of 16 patients with mesial temporal lobe epilepsy who have been
treated successfully (15 completely seizure free and 1 with rare, nondisa
bling seizures) without significant complication. After additional follow up
to demonstrate the absence of long term consequences, this fascinating new
approach could change epilepsy surgery practice dramatically.
The Treatment of Movement Disorders Using Gamma Knife
Stereotactic Radiosurgery 379
Christopher M. Duma, Deane Jacques, and Oleg V. Kopyov
In this era of modern neurosurgery, we are able to provide adequate amelio¬
ration of disabling symptoms for the small subset of patients who have
xii CONTENTS
conditions that may make them unacceptable candidates for invasive stereo
tactic neurosurgical intervention. Gamma Knife radiosurgical thalamotomy
is an effective and useful alternative to invasive radiofrequeney techniques
for patients at high surgical risk. The mechanical accuracy of the gamma
unit combined with the anatomical accuracy of high resolution magnetic
resonance imaging makes radiosurgical lesioning safe and precise.
Index 391
Subscription Information Inside back cover
CONTENTS x
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| spelling | Applications of radiosurgery Douglas Kondziolka, guest ed. Philadelphia [u.a.] Saunders 1999 XIII S., S. 157 - 394 Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Neurosurgery clinics of North America 10,2 Radiosurgery Strahlentherapie (DE-588)4057833-1 gnd rswk-swf Hirnkrankheit (DE-588)4025013-1 gnd rswk-swf Stereotaxie (DE-588)4203805-4 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Hirnkrankheit (DE-588)4025013-1 s Strahlentherapie (DE-588)4057833-1 s Stereotaxie (DE-588)4203805-4 s DE-604 Kondziolka, Douglas Sonstige oth Neurosurgery clinics of North America 10,2 (DE-604)BV002758938 10,2 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008564654&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Applications of radiosurgery Neurosurgery clinics of North America Radiosurgery Strahlentherapie (DE-588)4057833-1 gnd Hirnkrankheit (DE-588)4025013-1 gnd Stereotaxie (DE-588)4203805-4 gnd |
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| title | Applications of radiosurgery |
| title_auth | Applications of radiosurgery |
| title_exact_search | Applications of radiosurgery |
| title_full | Applications of radiosurgery Douglas Kondziolka, guest ed. |
| title_fullStr | Applications of radiosurgery Douglas Kondziolka, guest ed. |
| title_full_unstemmed | Applications of radiosurgery Douglas Kondziolka, guest ed. |
| title_short | Applications of radiosurgery |
| title_sort | applications of radiosurgery |
| topic | Radiosurgery Strahlentherapie (DE-588)4057833-1 gnd Hirnkrankheit (DE-588)4025013-1 gnd Stereotaxie (DE-588)4203805-4 gnd |
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