Effects of extracellular adenosine and ATP on cardiomyocytes:
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Austin, Tex.
Landes
1998
|
| Series: | Molecular biology intelligence unit
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | 225 S. graph. Darst. |
| ISBN: | 1570595240 |
Staff View
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| 245 | 1 | 0 | |a Effects of extracellular adenosine and ATP on cardiomyocytes |c [ed. by] Amir Pelleg ... |
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| adam_text | i, CONTENTS =r
Introduction: Historical Milestones 1
Amir Pelleg and Luiz Belardinelli
1. Adenosine Receptor Mediated Signal Transduction 7
Mark E. Olah and Gary L. Stiles
Introduction 7
Adenosine Receptors and Signal Transduction Pathways 8
Structural Determinants of AR Signal Transduction 23
Conclusions 31
2. Adenosine Metabolism and Transport
in the Mammalian Heart 39
Jtirgen Schroder, Andreas Deussen and Ulrich K.M. Decking
Overview of Adenosine Metabolism and Energy Balance 44
Pathways of Adenosine Production in Normoxia
andHypoxia 46
The Endothelium as a Metabolic Barrier for Adenosine 48
Cardiac Energy Status and Adenosine Metabolism 63
AMP Degradation and Cardiac Energy Status 74
Conclusions and Perspectives 75
3. Cardiac Electrophysiology of Adenosine:
Cellular Basis and Clinical Implications 87
M.J. Pekka Raatikainen, Donn M. Dennis and Luiz Belardinelli
Introduction 87
Cardiac Electrophysiological Effects of Adenosine 88
Effects of Adenosine on Membrane Ion Currents 97
Antiarrhythmic Effects of Adenosine 103
Proarrhythmic Effects of Adenosine 113
Anti and Proarrhythmic Effects of Endogenous Adenosine:
Potential Therapeutic Implications 116
Summary and Future Directions 120
4. Protective Effects of Adenosine in Reversibly
and Irreversibly Injured Ischemic Myocardium 133
Robert D. Lasley
Adenosine Metabolism and Myocardial Ischemia 134
Adenosine and Postischemic Ventricular Function 137
Adenosine Receptors and Myocardial Ischemic Injury 138
Adenosine Receptors
and Postischemic Ventricular Function 140
Adenosine and Myocardial Infarct Size 145
Mechanisms of Adenosine Mediated Cardioprotection 152
Proposed Mechanism(s) of Adenosine A! Receptor
Mediated Cardioprotection 154
I ¦
Adenosine Cardioprotection and ATP Sensitive
K+Channels 156
Adenosine Cardioprotection and Protein Kinase C 158
Cardioprotection and Adenosine A3 Receptors 161
Summary 162
5. The Role of Adenosine in the Regulation
of Cardiac Function: The Effect of Aging 173
Guoping Cat, Hoau Yan Wang and Eitan Friedman
Introduction 173
Age Related Changes in Cardiac Effects of Adenosine:
A Brief Overview 176
Age Related Changes in the Coupling of A! Adenosine
Receptors to G Proteins 182
Summary 188
6. Direct and Indirect Effects of Extracellular ATP
on Cardiac Myocytes 197
Amir Pelleg and Guy Vassort
Introduction 197
Direct Actions of ATP on Cardiac Cells 198
Indirect Actions of ATP 211
Index 223
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| illustrated | Illustrated |
| indexdate | 2024-07-09T18:24:30Z |
| institution | BVB |
| isbn | 1570595240 |
| language | English |
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| physical | 225 S. graph. Darst. |
| publishDate | 1998 |
| publishDateSearch | 1998 |
| publishDateSort | 1998 |
| publisher | Landes |
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| series2 | Molecular biology intelligence unit |
| spelling | Effects of extracellular adenosine and ATP on cardiomyocytes [ed. by] Amir Pelleg ... Austin, Tex. Landes 1998 225 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Molecular biology intelligence unit Adenosine triphosphate Physiological effect Adenosine Physiological effect Heart cells Heart Physiology Extrazellulärraum (DE-588)4205506-4 gnd rswk-swf Herzmuskelzelle (DE-588)4127327-8 gnd rswk-swf Adenosin (DE-588)4130804-9 gnd rswk-swf ATP (DE-588)4143345-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Herzmuskelzelle (DE-588)4127327-8 s Adenosin (DE-588)4130804-9 s Extrazellulärraum (DE-588)4205506-4 s DE-604 ATP (DE-588)4143345-2 s Pelleg, Amir Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008310735&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Effects of extracellular adenosine and ATP on cardiomyocytes Adenosine triphosphate Physiological effect Adenosine Physiological effect Heart cells Heart Physiology Extrazellulärraum (DE-588)4205506-4 gnd Herzmuskelzelle (DE-588)4127327-8 gnd Adenosin (DE-588)4130804-9 gnd ATP (DE-588)4143345-2 gnd |
| subject_GND | (DE-588)4205506-4 (DE-588)4127327-8 (DE-588)4130804-9 (DE-588)4143345-2 (DE-588)4143413-4 |
| title | Effects of extracellular adenosine and ATP on cardiomyocytes |
| title_auth | Effects of extracellular adenosine and ATP on cardiomyocytes |
| title_exact_search | Effects of extracellular adenosine and ATP on cardiomyocytes |
| title_full | Effects of extracellular adenosine and ATP on cardiomyocytes [ed. by] Amir Pelleg ... |
| title_fullStr | Effects of extracellular adenosine and ATP on cardiomyocytes [ed. by] Amir Pelleg ... |
| title_full_unstemmed | Effects of extracellular adenosine and ATP on cardiomyocytes [ed. by] Amir Pelleg ... |
| title_short | Effects of extracellular adenosine and ATP on cardiomyocytes |
| title_sort | effects of extracellular adenosine and atp on cardiomyocytes |
| topic | Adenosine triphosphate Physiological effect Adenosine Physiological effect Heart cells Heart Physiology Extrazellulärraum (DE-588)4205506-4 gnd Herzmuskelzelle (DE-588)4127327-8 gnd Adenosin (DE-588)4130804-9 gnd ATP (DE-588)4143345-2 gnd |
| topic_facet | Adenosine triphosphate Physiological effect Adenosine Physiological effect Heart cells Heart Physiology Extrazellulärraum Herzmuskelzelle Adenosin ATP Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008310735&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT pellegamir effectsofextracellularadenosineandatponcardiomyocytes |