An introduction to clinical immunology and serology:
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Philadelphia
Davis
1998
|
| Edition: | 2. ed. |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | Frühere Aufl. u.d.T.: Widmann, Frances K.: An introduction to clinical immunology |
| Physical Description: | XIV, 473 S. Ill., graph. Darst. |
| ISBN: | 0803603029 |
Staff View
MARC
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Record in the Search Index
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|---|---|
| adam_text | PART I
PRINCIPLES OF IMMUNE FUNCTION 1
1 Introductory Concepts 3
Innate and Adaptive Immunity 8
Biologically Significant Molecules 11
Cells and Cell Properties 13
Summary 19
2 The Immune System 22
Nature of Immune Reactions 22
Organs of the Immune System 25
The Mononuclear Phagocyte System 31
Summary 33
3 Major Histocompatibility Complex: The HLA System 37
Organization and Inheritance of HLA 38
Structure and Function of MHC Molecules 40
Genetic and Cellular Significance 46
Clinical Significance 48
Summary 50
4 Principles of Immune Activation 54
Determinants of Immunity 54
The Nature of Recognition 58
Primary Exposure to Antigen 60
Subsequent Exposure to Antigen 68
Summary 70
5 Lymphocyte Populations 73
How to Identify Cells 74
Development of Lymphocytes 80
Development of T Lymphocytes 82
Development of B Lymphocytes 91
xi
Jril
Natural Killer Cells 93
Summary 95
6 Immunoglobulins 99
Immunoglobulin Structure 100
Specific Immunoglobulins 107
Genetics of Immunoglobulin Diversity Ill
Immunoglobulin Allotypes and Idiotypes 118
T Cell Receptor Diversity 120
Summary 121
7 Cytokines, Cellular Cooperation, and Cell Mediated Immunity 126
Cellular Interactions and Cytokines 126
Humoral Immune Response 133
Cell Mediated Immunity 134
Summary 140
8 The Complement System 145
General Properties of Complement 146
The Classical Pathway 149
The Alternative Pathway 155
The Membrane Attack Unit 158
Control Over the System 159
Summary 164
PART n
CLINICAL APPLICATIONS 169
9 Protective Immunity 171
Passive Immunity 172
Active Immunity 174
Events That Provoke Immune Responses 181
Immunity at Surfaces 185
Effects of Antibodies 187
Cell Mediated Immune Events 189
Summary 192
10 Immunodeficiency Conditions 197
Manifestations of Immunodeficiency 199
Acquired Conditions of Depressed Immunity 200
Primary Conditions Affecting Both T Cells and B Cells 206
Primary Disorders of T Cells 208
Primary Disorders of B Cells 209
Deficiencies in the Complement System 211
Abnormalities of Phagocytosis 213
Summary 215
xiH
11 Neoplasms of the Immune System 221
Classification of Neoplasms 222
Malignancies of Lymphoid Precursors 224
Neoplasms of Mature B Lymphocytes 226
Neoplasms of Plasma Cells 230
Waldenstrom s Macroglobulinemia 233
Malignancies of Mature T Lymphocytes 236
Hodgkin s Disease 238
Neoplasms of Monocyte/Macrophages 241
Summary 242
12 Inflammation and Immune Mediated Diseases 247
Inflammation 248
Immune Mediated Inflammation 253
Type I Immunopathology 255
Type II Immunopathology 263
Type III Immunopathology 267
Type IV Delayed Hypersensitivity Disorders 272
Autoimmune Disorders 276
Summary 287
13 Transplantation Immunology 294
Principles of Transplantation 295
Rejection Phenomena 299
Testing Before Transplantation 303
Immunosuppression 308
Bone Marrow Transplantation 312
Summary 314
14 Cancer Immunology 319
Nature of Cancer 319
Tumor Immunity 326
Cancer Immunotherapy 333
Summary 336
PART m
LABORATORY APPLICATIONS 341
15 General Laboratory Principles 343
End Points 343
Manipulating End Points 349
Summary 354
16 Laboratory Procedures Based on Precipitation 358
Physical Aspects of Precipitation 358
Double Diffusion 362
Single Diffusion 368
Techniques that Measure Light 371
Summary 371
xiv
17 Methods Based on Agglutination 375
Principles of the Reaction 375
Agglutination Procedures 381
Inhibition of Agglutination 386
Quality Assurance 389
Summary 390
18 Receptor Ligand Assays 395
Interaction of Receptor and Ligand 395
Some Selected Procedures 403
Summary 416
19 Complement in Laboratory Testing 421
Complement in the Demonstration of Anitbodies 421
Demonstration that Antigen Antibody Reaction Has Occurred 425
Measurement of Complement 427
Measurement of Complement Receptors 429
Summary 430
Glossary 433
Appendix 453
Index 457
|
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| dewey-sort | 3616.07 19 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| edition | 2. ed. |
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| genre_facet | Einführung |
| id | DE-604.BV012146532 |
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| indexdate | 2024-07-09T18:22:29Z |
| institution | BVB |
| isbn | 0803603029 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-008226263 |
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| physical | XIV, 473 S. Ill., graph. Darst. |
| publishDate | 1998 |
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| publisher | Davis |
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| spelling | Widmann, Frances K. Verfasser aut An introduction to clinical immunology and serology Francis K. Widmann ; Carol Ann Itatani 2. ed. Philadelphia Davis 1998 XIV, 473 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Frühere Aufl. u.d.T.: Widmann, Frances K.: An introduction to clinical immunology Immunologie clinique Sérologie Immune System Immunity Immunology Immunopathology Serologic Tests methods Immunologie (DE-588)4026637-0 gnd rswk-swf (DE-588)4151278-9 Einführung gnd-content Immunologie (DE-588)4026637-0 s DE-604 Itatani, Carol Ann Verfasser aut HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008226263&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Widmann, Frances K. Itatani, Carol Ann An introduction to clinical immunology and serology Immunologie clinique Sérologie Immune System Immunity Immunology Immunopathology Serologic Tests methods Immunologie (DE-588)4026637-0 gnd |
| subject_GND | (DE-588)4026637-0 (DE-588)4151278-9 |
| title | An introduction to clinical immunology and serology |
| title_auth | An introduction to clinical immunology and serology |
| title_exact_search | An introduction to clinical immunology and serology |
| title_full | An introduction to clinical immunology and serology Francis K. Widmann ; Carol Ann Itatani |
| title_fullStr | An introduction to clinical immunology and serology Francis K. Widmann ; Carol Ann Itatani |
| title_full_unstemmed | An introduction to clinical immunology and serology Francis K. Widmann ; Carol Ann Itatani |
| title_short | An introduction to clinical immunology and serology |
| title_sort | an introduction to clinical immunology and serology |
| topic | Immunologie clinique Sérologie Immune System Immunity Immunology Immunopathology Serologic Tests methods Immunologie (DE-588)4026637-0 gnd |
| topic_facet | Immunologie clinique Sérologie Immune System Immunity Immunology Immunopathology Serologic Tests methods Immunologie Einführung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008226263&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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