Chlordimeform:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Geneva
World Health Organization
1998
|
| Ausgabe: | 1. draft |
| Schriftenreihe: | Environmental health criteria
199 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIX, 159 S. |
| ISBN: | 9241571993 |
Internformat
MARC
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| 245 | 1 | 0 | |a Chlordimeform |c prepared by P. J. Abbott |
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| 264 | 1 | |a Geneva |b World Health Organization |c 1998 | |
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| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
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| 490 | 1 | |a Environmental health criteria |v 199 | |
| 650 | 7 | |a Arbeidshygiëne |2 gtt | |
| 650 | 7 | |a Blootstelling |2 gtt | |
| 650 | 7 | |a CHEMICAL SAFETY |2 unbist | |
| 650 | 7 | |a CHEMICALS |2 unbist | |
| 650 | 7 | |a Chloordimeform |2 gtt | |
| 650 | 4 | |a Chlordiméform - Aspect de l'environnement | |
| 650 | 4 | |a Chlordiméform - Effets physiologiques | |
| 650 | 4 | |a Chlordiméform - Sécurité - Mesures | |
| 650 | 4 | |a Chlordiméform - Toxicologie | |
| 650 | 7 | |a Clordimeformo - Aspectos ambientales |2 embne | |
| 650 | 7 | |a Clordimeformo - Toxicidad |2 embne | |
| 650 | 7 | |a ENVIRONMENTAL HEALTH |2 unbist | |
| 650 | 7 | |a Gezondheidseffecten |2 gtt | |
| 650 | 7 | |a Pesticidas |2 larpcal | |
| 650 | 7 | |a Toxiciteit |2 gtt | |
| 650 | 4 | |a Chlorphenamidine |x adverse effects | |
| 650 | 4 | |a Chlrophenamidine |x toxicity | |
| 650 | 4 | |a Environmental Exposure | |
| 650 | 4 | |a Environmental Health | |
| 650 | 4 | |a Environmental health | |
| 650 | 4 | |a Insecticides |x Toxicology | |
| 650 | 4 | |a Occupational Exposure | |
| 650 | 4 | |a Organochlorine compounds |x Toxicology | |
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Datensatz im Suchindex
| _version_ | 1804126736218062848 |
|---|---|
| adam_text | CONTENTS
ENVIRONMENTAL HEALTH CRITERIA FOR
CHLORDIMEFORM
PREAMBLE ix
ABBREVIATIONS xix
1. SUMMARY 1
1.1 Identity, physical and chemical properties,
and analytical methods 1
1.2 Sources of human and environmental exposure 1
1.3 Environmental transport, distribution and
transformation 1
1.4 Environmental levels and human exposure 2
1.5 Kinetics and metabolism in laboratory animals
and humans 3
1.6 Effects on laboratory mammals and in vitro
test systems 3
1.7 Effects on humans 4
1.8 Effects on other organisms in the laboratory
and field 5
1.9 Evaluation of human health risks and effects
on the environment 5
1.10 Conclusions and recommendations 6
2. IDENTITY, PHYSICAL AND CHEMICAL
PROPERTIES, AND ANALYTICAL METHODS 7
2.1 Identity 7
2.2 Physical and chemical properties 8
2.3 Conversion factors 10
2.4 Analytical methods 10
2.4.1 Plants 10
2.4.2 Soil 11
2.4.3 Water 11
2.4.4 Formulations 12
;;/
EHC199: Chlordlmeform
2.4.5 Air 12
2.4.6 Urine 12
2.4.7 Tissues 13
3. SOURCES OF HUMAN AND ENVIRONMENTAL
EXPOSURE 14
3.1 Natural occurrence 14
3.2 Anthropogenic sources 14
3.2.1 Production levels and processes 14
3.2.2 Uses 15
4. ENVIRONMENTAL TRANSPORT, DISTRIBUTION
AND TRANSFORMATION 17
4.1 Transport and distribution between media 17
4.1.1 Air 17
4.1.2 Water 17
4.1.3 Soil 18
4.1.4 Vegetation and wildlife 19
4.1.5 Entry into food chain 22
4.2 Biotransformation 22
4.2.1 Degradation in plants 22
4.2.2 Degradation in soils 25
4.2.3 Bioaccumulation 26
4.3 Ultimate fate following use 26
5. ENVIRONMENTAL LEVELS AND HUMAN
EXPOSURE 27
5.1 Environmental levels 27
5.1.1 Air and water 27
5.1.2 Soil 27
5.2 General population exposure 27
5.2.1 Environmental sources 27
5.2.2 Residues in raw produce 28
5.2.3 Residues in processed food 31
5.3 Occupational exposure during manufacture,
formulation or use 33
5.3.1 Exposure during manufacture and
formulation 33
5.3.2 Exposure during use 34
6. KINETICS AND METABOLISM IN LABORATORY
ANIMALS AND HUMANS 40
6.1 Absorption, distribution and excretion 40
6.1.1 Mouse and rat 40
6.1.2 Other species 42
6.1.3 Human 43
6.2 Metabolic transformation 43
6.2.1 Mouse and rat 43
6.2.2 Other species 47
6.2.3 In vitro studies 48
7. EFFECTS ON EXPERIMENTAL ANIMALS AND
IN VITRO TEST SYSTEMS 50
7.1 Single exposure 50
7.1.1 Oral 50
7.1.2 Other routes 50
7.2 Short term exposure 52
7.2.1 Dietary 52
7.2.1.1 Mouse 53
7.2.1.2 Rat 55
7.2.1.3 Dog 58
7.2.2 Intubation 58
7.2.2.1 Rat 58
7.3 Long term dietary exposure 58
7.3.1 Mouse 58
7.3.2 Rat 59
7.4 Skin and eye irritation; skin sensitization 64
7.5 Reproductive toxicity, embryotoxicity and
teratogenicity 64
7.5.1 Reproductive toxicity 64
7.5.1.1 Rat 64
7.5.1.2 Hamster 65
7.5.2 Embryotoxicity and teratology 65
7.5.2.1 Rat 65
7.5.2.2 Rabbit 66
7.6 Mutagenicity and related end points 66
7.6.1 DNA damage and repair 72
7.6.2 Mutation 73
7.6.3 Chromosome damage 74
7.6.4 Cell transformation 75
EHC199: Chlordlmeform
7.7 Carcinogenicity 75
7.7.1 Mouse 75
7.7.2 Rat 82
7.8 Other special studies 83
7.8.1 Immunotoxicity 83
7.8.2 Behavioural effects 84
7.8.3 Pharmacological and biochemical effects 85
7.9 Factors modifying toxicity 87
7.10 Mechanisms of toxicity mode of action 87
7.10.1 Mechanism of acute toxicity 87
7.10.2 Mechanism of carcinogenicity 89
8. EFFECTS ON HUMANS 92
8.1 General population exposure 92
8.1.1 Acute poisoning incidents 92
8.2 Occupational exposure 92
8.2.1 Acute poisoning incidents 92
8.2.2 Effects of long term exposure 99
8.2.3 Epidemiological studies 106
8.2.3.1 4 Chloro o toluidine 106
8.2.3.2 Chlordimeform 107
9. EFFECTS ON OTHER ORGANISMS IN THE
LABORATORY AND FIELD 114
9.1 Laboratory experiments 114
9.1.1 Microorganisms 114
9.1.2 Aquatic organisms 114
9.1.2.1 Plants 114
9.1.2.2 Invertebrates 114
9.1.2.3 Vertebrates 114
9.1.3 Terrestrial organisms 114
9.1.3.1 Plants 114
9.1.3.2 Invertebrates 114
9.1.3.3 Vertebrates 118
9.2 Field observations 119
9.2.1 Microorganisms 119
9.2.2 Aquatic organisms 119
9.2.3 Terrestrial organisms 119
9.2.3.1 Plants 119
9.2.3.2 Invertebrates 120
9.2.3.3 Vertebrates 120
10. EVALUATION OF HUMAN HEALTH RISKS AND
EFFECTS ON THE ENVIRONMENT 121
10.1 Evaluation of human health risks 121
10.1.1 Exposure 121
10.1.2 Toxicity 121
10.1.3 Risk evaluation 122
10.2 Evaluation of effects on the environment 122
11. CONCLUSIONS AND RECOMMENDATIONS FOR
PROTECTION OF HUMAN HEALTH AND THE
ENVIRONMENT 123
11.1 Conclusions 123
11.2 Recommendations for protection of human health
and the environment 123
12. FURTHER RESEARCH 124
13. PREVIOUS EVALUATIONS BY INTERNATIONAL
BODIES 125
REFERENCES 126
RESUME 146
RESUMEN 153
|
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| callnumber-subject | RA - Public Medicine |
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| dewey-full | 363.1792 |
| dewey-hundreds | 300 - Social sciences |
| dewey-ones | 363 - Other social problems and services |
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| dewey-search | 363.1792 |
| dewey-sort | 3363.1792 |
| dewey-tens | 360 - Social problems and services; associations |
| discipline | Soziologie |
| edition | 1. draft |
| format | Book |
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| id | DE-604.BV012129065 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-09T18:22:11Z |
| institution | BVB |
| isbn | 9241571993 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-008214132 |
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| owner_facet | DE-12 DE-Er8 |
| physical | XIX, 159 S. |
| publishDate | 1998 |
| publishDateSearch | 1998 |
| publishDateSort | 1998 |
| publisher | World Health Organization |
| record_format | marc |
| series | Environmental health criteria |
| series2 | Environmental health criteria |
| spelling | Abbott, P. J. Verfasser aut Chlordimeform prepared by P. J. Abbott 1. draft Geneva World Health Organization 1998 XIX, 159 S. txt rdacontent n rdamedia nc rdacarrier Environmental health criteria 199 Arbeidshygiëne gtt Blootstelling gtt CHEMICAL SAFETY unbist CHEMICALS unbist Chloordimeform gtt Chlordiméform - Aspect de l'environnement Chlordiméform - Effets physiologiques Chlordiméform - Sécurité - Mesures Chlordiméform - Toxicologie Clordimeformo - Aspectos ambientales embne Clordimeformo - Toxicidad embne ENVIRONMENTAL HEALTH unbist Gezondheidseffecten gtt Pesticidas larpcal Toxiciteit gtt Chlorphenamidine adverse effects Chlrophenamidine toxicity Environmental Exposure Environmental Health Environmental health Insecticides Toxicology Occupational Exposure Organochlorine compounds Toxicology Umweltbelastung (DE-588)4061619-8 gnd rswk-swf Toxikologie (DE-588)4060538-3 gnd rswk-swf Chlordimeform (DE-588)4518377-6 gnd rswk-swf Chlordimeform (DE-588)4518377-6 s Toxikologie (DE-588)4060538-3 s DE-604 Umweltbelastung (DE-588)4061619-8 s Environmental health criteria 199 (DE-604)BV000011459 199 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008214132&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Abbott, P. J. Chlordimeform Environmental health criteria Arbeidshygiëne gtt Blootstelling gtt CHEMICAL SAFETY unbist CHEMICALS unbist Chloordimeform gtt Chlordiméform - Aspect de l'environnement Chlordiméform - Effets physiologiques Chlordiméform - Sécurité - Mesures Chlordiméform - Toxicologie Clordimeformo - Aspectos ambientales embne Clordimeformo - Toxicidad embne ENVIRONMENTAL HEALTH unbist Gezondheidseffecten gtt Pesticidas larpcal Toxiciteit gtt Chlorphenamidine adverse effects Chlrophenamidine toxicity Environmental Exposure Environmental Health Environmental health Insecticides Toxicology Occupational Exposure Organochlorine compounds Toxicology Umweltbelastung (DE-588)4061619-8 gnd Toxikologie (DE-588)4060538-3 gnd Chlordimeform (DE-588)4518377-6 gnd |
| subject_GND | (DE-588)4061619-8 (DE-588)4060538-3 (DE-588)4518377-6 |
| title | Chlordimeform |
| title_auth | Chlordimeform |
| title_exact_search | Chlordimeform |
| title_full | Chlordimeform prepared by P. J. Abbott |
| title_fullStr | Chlordimeform prepared by P. J. Abbott |
| title_full_unstemmed | Chlordimeform prepared by P. J. Abbott |
| title_short | Chlordimeform |
| title_sort | chlordimeform |
| topic | Arbeidshygiëne gtt Blootstelling gtt CHEMICAL SAFETY unbist CHEMICALS unbist Chloordimeform gtt Chlordiméform - Aspect de l'environnement Chlordiméform - Effets physiologiques Chlordiméform - Sécurité - Mesures Chlordiméform - Toxicologie Clordimeformo - Aspectos ambientales embne Clordimeformo - Toxicidad embne ENVIRONMENTAL HEALTH unbist Gezondheidseffecten gtt Pesticidas larpcal Toxiciteit gtt Chlorphenamidine adverse effects Chlrophenamidine toxicity Environmental Exposure Environmental Health Environmental health Insecticides Toxicology Occupational Exposure Organochlorine compounds Toxicology Umweltbelastung (DE-588)4061619-8 gnd Toxikologie (DE-588)4060538-3 gnd Chlordimeform (DE-588)4518377-6 gnd |
| topic_facet | Arbeidshygiëne Blootstelling CHEMICAL SAFETY CHEMICALS Chloordimeform Chlordiméform - Aspect de l'environnement Chlordiméform - Effets physiologiques Chlordiméform - Sécurité - Mesures Chlordiméform - Toxicologie Clordimeformo - Aspectos ambientales Clordimeformo - Toxicidad ENVIRONMENTAL HEALTH Gezondheidseffecten Pesticidas Toxiciteit Chlorphenamidine adverse effects Chlrophenamidine toxicity Environmental Exposure Environmental Health Environmental health Insecticides Toxicology Occupational Exposure Organochlorine compounds Toxicology Umweltbelastung Toxikologie Chlordimeform |
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