Lantibiotics and related peptides:
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Book |
| Language: | German |
| Published: |
Berlin [u.a.]
Springer
1998
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | Literaturangaben |
| Physical Description: | 224 S. Ill., graph. Darst. |
| ISBN: | 3540636005 1570595151 |
Staff View
MARC
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| 245 | 1 | 0 | |a Lantibiotics and related peptides |c Ralph W. Jack ; Gabriele Bierbaum ; Hans-Georg Sahl |
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Record in the Search Index
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| adam_text |
I CONTENTS t
1. Antimicrobial Peptides 1
Introduction 1
Nonribosomal Peptide Antibiotics 2
Defense Peptides of Eukaryotic Organisms 9
Bacteriocins Without Post Translational Modifications 16
Modified Bacteriocins—The Lantibiotics
and Microcin B17 25
Conclusions 35
2. Chemistry and Structure 41
Introduction 41
Sources and General Characteristics 41
Structures of Lantibiotics 47
Structure of Microcin B17 74
Conclusions , 76
3. Molecular Genetics of Biosynthesis 85
Introduction , 85
How to Make Modified Peptides—
Modification Reactions 85
Gene Clusters 91
Regulation of Biosynthesis 106
Structural Gene Products 111
Conclusions 116
4. Modification Enzymes 123
Introduction 123
Dehydrating and Thioether Forming Enzymes 124
Oxidative Decarboxylases 130
Microcin B17 Synthase 133
Processing Peptidases 134
Transport Systems 138
5. Producer Self Protection—Immunity 147
Introduction 147
Immunity Peptides/Proteins 148
ABC Transporter Pumps 151
Mechanisms of Resistance of Non Producer Strains 154
Conclusions 155
6. Biological Activities 157
Introduction .157
Type A Lantibiotics 158
Type B Lantibiotics 176
Are There Other Biological Activities of Lantibiotics? 182
Microcins .183
Conclusions 184
7. Genetic Engineering of Lantibiotics 191
Introduction 191
Construction of Expression Systems 192
Function of Modified Residues 197
Optimization of Lantibiotics 200
8. The Future: Biotechnology 207
Introduction 207
Biomedical Applications 208
Agro Food Applications 210
Biosynthetic Enzymes 213
Conclusions 214
Color Insert • 1 217
Index 219 |
| any_adam_object | 1 |
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| dewey-sort | 3615 3329 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Book |
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| id | DE-604.BV011876160 |
| illustrated | Illustrated |
| indexdate | 2024-09-24T00:19:55Z |
| institution | BVB |
| isbn | 3540636005 1570595151 |
| language | German |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-008024479 |
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| physical | 224 S. Ill., graph. Darst. |
| publishDate | 1998 |
| publishDateSearch | 1998 |
| publishDateSort | 1998 |
| publisher | Springer |
| record_format | marc |
| spelling | Jack, Ralph W. Verfasser aut Lantibiotics and related peptides Ralph W. Jack ; Gabriele Bierbaum ; Hans-Georg Sahl Berlin [u.a.] Springer 1998 224 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Literaturangaben Anti-Bacterial Agents Peptide antibiotics Congresses Peptides Peptidantibiotikum (DE-588)4173714-3 gnd rswk-swf Lantibiotikum (DE-588)4305682-9 gnd rswk-swf (DE-588)1071861417 Konferenzschrift gnd-content Peptidantibiotikum (DE-588)4173714-3 s DE-604 Lantibiotikum (DE-588)4305682-9 s Bierbaum, Gabriele Verfasser aut Sahl, Hans-Georg Verfasser aut HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008024479&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Jack, Ralph W. Bierbaum, Gabriele Sahl, Hans-Georg Lantibiotics and related peptides Anti-Bacterial Agents Peptide antibiotics Congresses Peptides Peptidantibiotikum (DE-588)4173714-3 gnd Lantibiotikum (DE-588)4305682-9 gnd |
| subject_GND | (DE-588)4173714-3 (DE-588)4305682-9 (DE-588)1071861417 |
| title | Lantibiotics and related peptides |
| title_auth | Lantibiotics and related peptides |
| title_exact_search | Lantibiotics and related peptides |
| title_full | Lantibiotics and related peptides Ralph W. Jack ; Gabriele Bierbaum ; Hans-Georg Sahl |
| title_fullStr | Lantibiotics and related peptides Ralph W. Jack ; Gabriele Bierbaum ; Hans-Georg Sahl |
| title_full_unstemmed | Lantibiotics and related peptides Ralph W. Jack ; Gabriele Bierbaum ; Hans-Georg Sahl |
| title_short | Lantibiotics and related peptides |
| title_sort | lantibiotics and related peptides |
| topic | Anti-Bacterial Agents Peptide antibiotics Congresses Peptides Peptidantibiotikum (DE-588)4173714-3 gnd Lantibiotikum (DE-588)4305682-9 gnd |
| topic_facet | Anti-Bacterial Agents Peptide antibiotics Congresses Peptides Peptidantibiotikum Lantibiotikum Konferenzschrift |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008024479&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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