Hormones:
The newly revised and updated Hormones, Second Edition provides a comprehensive treatment of human hormones, viewed in light of modern theories of hormone action and in the context of current understanding of subcellular and cellular architecture and classical organ physiology. Each chapter presents...
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| Main Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
San Diego [u.a.]
Acad. Press
1997
|
| Edition: | 2. ed. |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Summary: | The newly revised and updated Hormones, Second Edition provides a comprehensive treatment of human hormones, viewed in light of modern theories of hormone action and in the context of current understanding of subcellular and cellular architecture and classical organ physiology. Each chapter presents a physiological description of the hormone system under consideration, followed by a listing of the mode-of-action of the hormone. This book includes significant advances in the molecular biology of receptors, hormones, and studies of hormone action that have transpired over the past five years. The text updates the material on enzymes relate to steroid metabolism and new hormone systems, as well as providing a new chapter on hormones and cancer. |
| Physical Description: | XIX, 558 S. Ill., graph. Darst. |
| ISBN: | 0125214413 |
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| 245 | 1 | 0 | |a Hormones |c Anthony W. Norman ; Gerald Litwack |
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| 264 | 1 | |a San Diego [u.a.] |b Acad. Press |c 1997 | |
| 300 | |a XIX, 558 S. |b Ill., graph. Darst. | ||
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| 520 | 3 | |a The newly revised and updated Hormones, Second Edition provides a comprehensive treatment of human hormones, viewed in light of modern theories of hormone action and in the context of current understanding of subcellular and cellular architecture and classical organ physiology. Each chapter presents a physiological description of the hormone system under consideration, followed by a listing of the mode-of-action of the hormone. This book includes significant advances in the molecular biology of receptors, hormones, and studies of hormone action that have transpired over the past five years. The text updates the material on enzymes relate to steroid metabolism and new hormone systems, as well as providing a new chapter on hormones and cancer. | |
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Preface to the First Edition xiii
Preface to the Second Edition xvii
CHAPTER
1
General Considerations of Hormones
I. Overview of Hormones, Receptors, and
Endocrinology 1
A. Introduction 1
B. Classes of Hormone Molecules 2
C. Classification of Hormonal
Communication Systems 2
D. General Concept of a Hormone
Receptor 7
E. Hormones and Cascade Systems 8
II. Biosynthesis of Hormones 9
A. Introduction 9
B. Biosynthesis of Peptide and
Protein Hormones 9
C. Regulation of Hormone Secretion 15
D. Oncogenes and Hormones 17
III. Hormone Receptors 17
A. Cellular Organization 17
B. Membrane Receptors 19
C. Intracellular Receptors 27
D. Measurement of Hormone Receptor
Interactions 29
E. Regulation of Hormone Receptors 32
IV. Mechanism of Hormonal Action 33
A. Hormone Entry into Target Cells 33
B. Receptor Mediated Transmembrane
Signaling 34
C. Steroid Hormone Regulation of
Gene Transcription 40
V. Summary 46
References 46
tents
CHAPTER
2
Steroid Hormones: Chemistry,
Biosynthesis, and Metabolism
I. Introduction 49
A. General Comments 49
B. Historical Perspective 50
II. Chemistry of Steroids 51
A. Basic Ring Structure 51
B. Classes of Steroids 51
C. Structural Modification 52
D. Asymmetric Carbons 52
E. Conformation of Steroids 55
F. Other Steroid Structures 56
III. Biosynthesis of Cholesterol 57
A. General Comments 57
B. Pathway of Production 57
C. Role of Sterol Carrier
Protein 60
D. Regulation of Cholesterol
Biosynthesis 60
E. Inhibitors of Cholesterol
Biosynthesis 63
IV. Biosynthesis of Steroids 65
A. Introduction 65
B. Biosynthesis of Pregnenolone
and Progestins 67
C. Biosynthesis by the Adrenal Cortex of
Glucocorticoids, Mineralocorticoids, and
Some Androgens 67
D. Biosynthesis of Androgens 71
E. Biosynthesis of Estrogens 72
F. Biosynthesis of Vitamin D Metabolites 72
G. Biosynthesis of Bile Acids 73
vi Coi
V. Properties of Enzymes Involved in Steroid
Metabolism 75
A. Introduction 75
B. P450 Steroid Hydroxylases 75
C. Other Enzymes of Steroid Metabolism 79
VI. Plasma Transport, Catabolism, and Excretion
of Steroid Hormones 81
A. General Comments 81
B. Plasma Transport of Steroid and
Thyroid Hormones 83
C. Measurements of Rates of Secretion and
Metabolic Clearance 83
D. Inactivation of Steroid Hormones 85
References 85
CHAPTER
3
Hypothalamic Releasing Hormones
I. Introduction 87
II. Anatomical, Morphological, and
Physiological Relationships 90
A. Hypothalamus 90
B. Blood Supply of Hypothalamus 91
C. Electrical Connections from the Brain to
the Hypothalamus 91
D. The Neuron 91
HI. Chemistry 92
IV. Biochemistry 96
A. Location of Releasing Hormones in the
Central Nervous System 96
B. Secretion of Releasing Hormones and
General Actions 99
C. Specific Regulators of Releasing
Hormones and Anterior Pituitary
Hormone Release 99
D. TRH and GnRH Receptors 100
E. Molecular Mechanisms of Action 101
V. Clinical Aspects 104
References 107
CHAPTER
4
Posterior Pituitary Hormones
I. Introduction 109
II. Anatomy and Development of the
Posterior Pituitary 111
ntents
III. Chemistry 111
A. Structures of Active and Substituted
Posterior Pituitary Hormones 111
B. Interaction of Posterior Pituitary
Hormones with Active Sites of
Neurophysins 112
IV. Biochemistry 114
A. Formation and Neurosecretion of Posterior
Pituitary Hormones 114
V. Biological and Molecular Actions 118
A. Role of VP (Antidiuretic Hormone) in the
Regulation of Body Fluids 118
B. The VP Target: The Kidney
Distal Tubule 120
C. Mechanism of Action of VP in the Kidney
Distal Tubule 120
D. Nature of Kidney VP Sensitive Adenylate
Cyclase 123
E. Effects of VP on the Liver 123
F. VP and ACTH Release 124
G. Behavioral Effects of VP 125
H. Overview of Regulation of Oxytocin
Secretion from the Posterior Pituitary 126
I. Mechanism of Action of OT 128
J. The OT Receptor 128
K. Degradation of Posterior Pituitary
Hormones 128
VI. Clinical Aspects 128
References 130
CHAPTER
5
Anterior Pituitary Hormones
I. Introduction 133
II. Anatomical, Morphological, and
Physiological Relationships 135
HI. Chemistry 137
A. Growth Hormone (GH) 137
B. Prolactin (PRL) 137
C. Thyroid Stimulating Hormone (TSH) 137
D. Follicle Stimulating Hormone (FSH) 138
E. Luteinizing Hormone (LH) 139
F. Adrenocorticotropic
Hormone (ACTH) 140
G. Melanocyte Stimulating
Hormone (MSH) 141
H. Lipotropin (/3 LPH) 142
IV. Biochemistry 142
A. Neural Controls 142
B. Interactions of TSH, FSH, and LH
with Receptors 142
Con
V. Prolactin 142
A. Regulation of Prolactin Release 145
B. Stress Induced Release of Prolactin 147
C. Prolactin Receptors in Nonmammary and
Mammary Tissues 147
VI. Growth Hormone 149
A. Growth Hormone Structure 149
B. Regulation of Growth Hormone
Secretion 151
C. The Growth Hormone Receptor (GHR) 155
D. Signal Transduction Process Initiated
by GHR 155
E. Growth Hormone and Somatomedins 156
F. Growth Hormone Signal
Transduction 157
VII. /3 Lipotropin 159
A. /3 Endorphin and Stress 159
B. j8 Endorphin Receptor 160
C. Processing of /3 Endorphin 160
VIII. Thyrotropic Hormone 161
A. Thyrotropic Receptor 161
IX. ACTH 162
X. Gonadotropic Hormones LH and FSH 162
XI. ACTH Receptor 164
XII. Clinical Aspects 166
References 168
CHAPTER
6
Thyroid Hormones
I. Introduction 169
A. Background 169
B. Iodine Metabolism 170
C. Metabolic Effects of Thyroid
Hormones 170
II. Anatomical and Morphological
Relationships 170
A. Thyroid Gland 170
HI. Chemistry 171
A. Endogenous Hormones 171
B. Thyroid Hormone Analogs 171
IV. Biochemistry 172
A. Thyroglobulin 172
B. Iodide Transport 175
C. Iodide Organification and Thyroid
Peroxidase 177
D. Secretion Mechanisms of Thyroid
Hormones 180
E. Systemic Transport of Thyroid
Hormone 181
itents vii
F. Thyroid Hormone Metabolism and
Catabolism 182
G. Antithyroid Drugs 183
V. Biological and Molecular Actions 183
A. Introductory Comments 183
B. Thyroid Hormone Receptor 186
C. Production of Biological
Responses 187
VI. Clinical Aspects 189
A. Hormone Deficiency 189
B. Hormone Excess 190
C. Measurement of Thyroid
Function 190
References 190
CHAPTER
7
Pancreatic Hormones:
Insulin and Glucagon
I. Introduction 193
A. Background Information 193
B. Regulation of Blood Glucose 194
C. Nutritional and Metabolic
Interrelationships 194
II. Anatomical, Morphological, and
Physiological Relationships 197
A. Introduction 197
B. Development and Embryologic
Origins 198
C. infrastructure of Pancreatic Islets 199
D. Vascularization and Innervation of
Pancreatic Islets 200
HI. Chemistry 201
A. Insulin 201
B. Glucagon 203
C. Pancreatic Polypeptide 204
D. Somatostatin 205
E. Islet Amyloid Polypeptide 205
F. Leptin 205
IV. Biochemistry 206
A. Biosynthesis of Hormones 206
B. Secretion of Pancreatic Hormones 208
C. Pharmacological Agents Related to
the Pancreas 215
D. Metabolism of Insulin and
Glucagon 216
V. Biological and Molecular Actions 217
A. Interactions with Target Tissues 217
B. Biological Actions 219
viii Co
VI. Clinical Aspects 224
A. Insulin 224
B. Glucagon 226
References 226
CHAPTER
8
Gastrointestinal Hormones
I. Introduction 229
A. Background 229
B. Resume of the Gastrointestinal
Hormones 230
C. Problems of Food Processing and
Digestion 230
II. Anatomical, Morphological, and
Physiological Relationships 231
A. Gastroenteropancreatic System 231
B. Stomach 231
C. Small and Large Intestines 233
D. Hormone Secreting Cells: Their
Distribution in the Gastroentero¬
pancreatic Complex 235
E. Coordination of Gastroenteropancreatic
Hormone Release 236
F. Brain Gut Axis 236
HI. Chemistry and Biochemistry 236
A. General Relationships 236
B. Cholecystokinin (CCK) 236
C. Gastrin 238
D. Secretin 238
E. Enkephalins 239
F. Enteroglucagon 239
G. GIP 239
H. Motilin 240
I. Neurotensin 240
J. Pancreatic Polypeptide Family (PP) 240
K. Somatostatin 240
L. Bombesin and Tachykinin Peptide
Families 241
M. Calcitonin Gene Related
Peptide 241
N. Endothelin 241
O. Galanin 242
P. Vasoactive Intestinal
Peptide (VIP) 242
IV. Biological and Molecular Actions 243
A. Gastric Acid Secretion 243
B. Pancreatic, Biliary, and Intestinal
Secretions 244
ntents
C. Motor Functions of the
Intestinal Tract 247
V. Clinical Aspects 247
A. Peptic Ulcer Disease 247
B. Zollinger EUison Syndrome 247
C. Carcinoid Syndrome 247
References 247
CHAPTER
9
Calcium Regulating Hormones:
Vitamin D, Parathyroid Hormone,
and Calcitonin
I. Introduction 251
A. Background Information 251
B. Calcium and Phosphorus
Homeostasis 252
II. Anatomical, Morphological, and
Physiological Relationships 253
A. Parathyroid Gland 253
B. Calcitonin Secreting Cells 254
C. Intestine 254
D. Kidney 255
E. Bone 255
HI. Chemistry and Biochemistry 258
A. Parathyroid Hormone 258
B. Parathyroid Hormone Related
Protein 259
C. Calcitonin 259
D. Vitamin D 259
IV. Biology and Physiological
Significance 262
A. Parathyroid Hormone 262
B. Parathyroid Hormone Related
Protein 266
C. Calcitonin 267
D. Vitamin D and Its Metabolites 267
E. Biology of Bone Remodeling 272
F. Integrated Actions of Parathyroid
Hormone, Calcitonin, and Vitamin D
Metabolites 274
V. Clinical Aspects 275
A. Parathyroid Hormone 275
B. Parathyroid Hormone Related
Protein 276
C. Calcitonin 276
D. Vitamin D 276
E. Osteoporosis 279
References 279
Coi
CHAPTER
10
Adrenal Corticoids
I. Introduction 281
II. Anatomy, Development, and Cellular Fine
Structure of the Adrenal Cortex 283
A. Glucocorticoid Targets 284
III. Chemistry and Biochemistry 285
A. Glucocorticoids and Stress 285
B. Corticotropin Releasing
Hormone (CRH) 291
C. Mode of Action of Releasing
Hormones (e.g., CRH) 291
D. Mode of Action of ACTH 291
E. Sources of Cholesterol and Production of
Glucocorticoids 293
F. Mechanism of Secretion of
Glucocorticoids 294
G. Transport of Glucocorticoids
in the Blood (CBG) 294
H. Feedback Effects of Glucocorticoids 295
IV. Biological and Molecular Actions 295
A. Molecular Actions of Glucocorticoids 295
B. Glucocorticoids, Analogs, and
Antiglucocorticoid Compounds 301
C. Catabolism of Glucocorticoids 304
D. Drugs Antagonizing Glucocorticoids 304
E. Anti inflammatory Actions 305
V. Glucocorticoid Receptor 306
VI. Zona Reticularis and
Dehydroepiandrosterone 310
VII. Mineralocorticoid Hormone 310
A. Introduction 310
B. Aldosterone Producing System 313
C. Aldosterone Receptor 314
D. Aldosterone Antagonists 315
E. Aldosterone Metabolism 315
VIII. Clinical Aspects 315
A. Glucocorticoids 315
B. Mineralocorticoids and Androgens 315
C. Congenital Adrenal Hyperplasia and
Others 317
References 317
CHAPTER
Hormones of the Adrenal Medulla
I. Introduction 319
itents ix
II. Anatomical, Morphological, and
Physiological Relationships 320
A. Introduction 320
B. Development of the Adrenal Medulla 320
C. Autonomic Nervous System and the
Adrenal Medulla 320
D. Histology of the Adrenal Medulla 320
III. Chemistry 321
IV. Hormone Action and Biochemistry 323
A. Biochemistry of the Chromaffin Cell of the
Adrenal Medulla 323
B. Regulation of Biosynthesis 325
C. Content of Neurosecretory Granules
and Secretion 326
D. Catabolism of Catecholamines 327
V. Actions of Epinephrine 328
A. General Effects of Catecholamines 328
B. Effects of Epinephrine on Glycogenolysis
in the Liver 331
C. Ligand Detection of the Adrenergic
Receptor Subclasses 335
D. Regulation of Adrenergic Receptors 335
VI. Enkephalins 337
VII. Clinical Aspects 338
References 339
CHAPTER
12
Androgens
I. Introduction 341
A. General Comments 341
B. Characteristics of a Male 341
II. Anatomical and Morphological Relationships
of the Male Reproductive System 342
A. Introduction 342
B. Testes 342
C. Duct System 343
D. Accessory Structures 344
E. Spermatozoa and Semen 344
III. Chemistry, Biochemistry, and Biological
Responses 345
A. Steroid Hormones 345
B. Steroid Hormone Binding Globulin 348
C. Peptide Hormones 348
IV. Physiological Relationships 350
A. Hypothalamus Pituitary Testicular
Axis 350
B. Ley dig Cell Control and Function 351
C. Seminiferous Tubule Function 351
D. Spermatogenesis 353
X Con
V. Molecular Actions 355
A. Production of Steroid Hormones 355
B. Cellular Mechanisms of Action(s) of
Androgens 355
VI. Clinical Aspects 358
A. Prostatic Cancer 358
B. Steroid 5a Reductase Deficiency 358
C. Male Hypogonadism 359
D. Cryptorchidism 359
E. Gynecomastia 359
F. Anabolic Steroids 359
G. Infertility 359
H. Male Contraception 359
References 359
CHAPTER
13
Estrogens and Progestins
I. Introduction 361
A. General Comments 361
B. Characteristics of a Female 362
II. Anatomical and Morphological Relationships
of the Female Reproductive System 362
A. Introduction 362
B. Ovaries 362
C. Corpus Luteum 365
D. Fallopian Tubes 365
E. Uterus 366
F. Vagina 367
HI. Chemistry, Biochemistry, and Biological
Responses 367
A. Steroid Hormones 367
B. Peptide Hormones 368
IV. Physiological Relationships 369
A. Puberty and Sexual Development 369
B. The Female Reproductive Cycle 370
C. Menopause 373
V. Biological and Molecular Actions 373
A. Cellular Mechanisms of Action of the
Reproductive Hormones 373
B. Mechanisms of Progesterone and Estrogen
Receptor Action (As Exemplified by the
Chick Oviduct System) 377
C. Hormonal Effects on Ovulation and the
Menstrual Cycle 378
D. Estrogen and Progestin Antagonists 379
VI. Clinical Aspects 380
A. Female Contraception 380
B. Anovulation 381
C. Hirsutism 384
D. Primary Amenorrhea 384
tents
E. Breast Cancer 384
F. Menopause 384
References 385
CHAPTER
14
Hormones of Pregnancy and Lactation
I. Introduction 387
A. General Comments 387
B. Sequence of Events in Reproduction 387
II. Anatomical and Morphological
Relationships 388
A. Implantation 388
B. Fetal Placental Decidual Unit 388
C. Mammary Glands 390
III. Chemistry, Biochemistry, and Biological
Responses 391
A. Pregnancy 391
B. Parturition 398
C. Lactation 399
IV. Cell Biology and Molecular Actions 400
A. Hormonal Aspects of Fertilization 400
B. Sex Determination 401
C. Pregnancy 405
D. Breasts and Lactation 406
V. Clinical Aspects 409
A. Pregnancy Gestational Neoplasms 409
B. Anomalies of Sex Determinants 409
C. Breast Cancer 410
D. Galactorrhea 411
References 411
CHAPTER
15
Hormones Related to the Kidney and
Cardiovascular System
I. Introduction 413
A. Background 413
B. Scope of This Chapter 414
II. Anatomical, Morphological, and
Physiological Relationships 414
A. The Kidney 414
B. Cardiovascular System 418
III. Homeostasis of Fluid, Electrolytes, and Blood
Pressure 420
A. Introduction 420
B. Renin Angiotensin II 421
(
C. Angiotensin I and II 421
D. Aldosterone Actions in Renal
Tubular Reabsorption 423
E. Atrial Natriuretic Protein System 425
F. Water Balance 427
G. Endothelins 427
H. Kallikreins and Kinins 431
I. Prostaglandins 431
J. Nitric Oxide System 433
K. Summary 434
IV. Hormones and Blood Cell Production 434
A. Introduction 434
B. Regulatory Factors 434
C. Cell Differentiation 435
D. Hematopoietic Regulating Factors 435
V. Hormones and Inflammation 439
A. Introduction 439
B. Inflammation Response 439
VI. Clinical Aspects 440
A. Hypertension 440
B. Aldosterone 441
C. Edematous Disorders 441
D. Nitric Oxide 442
E. Erythropoietin 442
References 442
CHAPTER
16
Prostaglandins
I. Introduction 445
A. Background 445
B. Structural Classes of Prostaglandin
(PG) Relatives 446
C. Classification of PGs 447
D. General Aspects of PGs 450
II. Chemistry 450
A. Conformation of PGs and
Thromboxanes (TX) 450
B. Phospholipase A2 Enzymes 450
III. Biochemistry 450
A. Biosynthesis 450
B. Metabolism 452
C. Binding Proteins and Receptors 452
IV. Biological Actions 454
A. PGF2a as an Agent for
Therapeutic Abortion 454
B. Pancreas 455
C. Ectopic Bone Resorption 455
D. Autonomic Nervous System 455
E. PGI2 in Fibroblasts 456
F. PGs and the Pain Mechanism 456
lontents X
G. Antihypertensive Renal Effects 458
H. The Platelet System 459
V. Leukotrienes (LTs) 459
A. Background 459
B. LT and Asthma 460
VI. Clinical Aspects 467
A. Abortion 467
B. Erectile Dysfunction 468
C. Gastroduodenal Ulceration 468
D. Myocardial Infarction 468
E. Implantation of Embryo 468
References 468
CHAPTER
17
Thymus Hormones
I. Introduction 471
A. Background 471
B. Immune System 473
II. Anatomical and Morphological
Relationships 474
HI. Cell Biology 475
IV. Chemistry and Biochemistry 476
A. Introduction 476
B. Thymosin a, 476
C. Thymosin /34 479
D. Thymosin Fraction 5 480
E. Thymic Humoral Factor (THF y2) 480
F. Thymopoietin 482
V. Biological and Molecular Actions 482
VI. Clinical Aspects 483
References 483
CHAPTER
18
Pineal Hormones
I. Introduction 485
A. General Comments 485
B. Evolutionary Aspects 485
II. Development 486
III. Anatomy and Cell Biology 487
IV. Chemistry 488
V. Biochemistry 488
VI. Biological and Molecular Actions 490
A. General Comments 490
B. Melatonin Receptor 491
C. Actions of Melatonin on Anterior
Pituitary 493
xii Cor
VII. Clinical Aspects 494
References 495
CHAPTER
19
Cell Growth Factors
I. Growth Factor Signal Transduction 497
II. Growth Hormone (GH) and
Somatomedins (IGFs) 498
III. Interaction of IGFs with Receptors 498
IV. Signal Transduction of Receptors for GH,
IGFs, and Insulin 499
V. Epidermal Growth Factor (EGF) Family 500
VI. Transforming Growth Factor /?
(TGF /3) Family 501
VII. Platelet Derived Growth Factor (PDGF) 503
VIII. Fibroblast Growth Factor (FGF) 505
IX. Nerve Growth Factor (NGF) 506
X. Hepatocyte Growth Factor
(HGF, Scatter Factor) 509
References 511
CHAPTER
20
Hormones and Cancer
I. Introduction 513
II. Relation of Some Hormones to Carcinogens
and Development of Cancer from
Inappropriate Hormonal Treatment 513
itents
III. Hormone Related Treatment of
Cancer 514
IV. Hormone Receptor Status of
Breast Cancers 517
V. Ectopic Production of Hormones by
Tumor Cells 519
VI. Oncogenes and Hormonal
Functions 520
VII. Conclusion 523
References 523
Appendix A
Compilation of Most Known Hormones in Higher
Mammals and Humans 525
Appendix B
Human Blood Concentrations of
Major Hormones 531
Appendix C
Clinically Relevant Endocrine Disorders 535
Appendix D
The Genetic Code 539
Appendix E
Amino Acid Abbreviations 541
Appendix F
Units of Measurement in Biological
Systems 543
Index 545
|
| any_adam_object | 1 |
| author | Norman, Anthony W. 1938- Litwack, Gerald |
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| dewey-hundreds | 800 - Literature (Belles-lettres) and rhetoric |
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| dewey-sort | 3812.4 15 |
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| discipline | Biologie Anglistik / Amerikanistik |
| edition | 2. ed. |
| format | Book |
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| id | DE-604.BV011783737 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:15:42Z |
| institution | BVB |
| isbn | 0125214413 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-007953613 |
| oclc_num | 37780742 |
| open_access_boolean | |
| owner | DE-29 DE-19 DE-BY-UBM DE-188 |
| owner_facet | DE-29 DE-19 DE-BY-UBM DE-188 |
| physical | XIX, 558 S. Ill., graph. Darst. |
| publishDate | 1997 |
| publishDateSearch | 1997 |
| publishDateSort | 1997 |
| publisher | Acad. Press |
| record_format | marc |
| spelling | Norman, Anthony W. 1938- Verfasser (DE-588)133112853 aut Hormones Anthony W. Norman ; Gerald Litwack 2. ed. San Diego [u.a.] Acad. Press 1997 XIX, 558 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier The newly revised and updated Hormones, Second Edition provides a comprehensive treatment of human hormones, viewed in light of modern theories of hormone action and in the context of current understanding of subcellular and cellular architecture and classical organ physiology. Each chapter presents a physiological description of the hormone system under consideration, followed by a listing of the mode-of-action of the hormone. This book includes significant advances in the molecular biology of receptors, hormones, and studies of hormone action that have transpired over the past five years. The text updates the material on enzymes relate to steroid metabolism and new hormone systems, as well as providing a new chapter on hormones and cancer. Hormones cabt Hormones Endocrine System Endocrine System Diseases Hormon (DE-588)4025864-6 gnd rswk-swf Hormon (DE-588)4025864-6 s DE-604 Litwack, Gerald Verfasser aut HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007953613&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Norman, Anthony W. 1938- Litwack, Gerald Hormones Hormones cabt Hormones Endocrine System Endocrine System Diseases Hormon (DE-588)4025864-6 gnd |
| subject_GND | (DE-588)4025864-6 |
| title | Hormones |
| title_auth | Hormones |
| title_exact_search | Hormones |
| title_full | Hormones Anthony W. Norman ; Gerald Litwack |
| title_fullStr | Hormones Anthony W. Norman ; Gerald Litwack |
| title_full_unstemmed | Hormones Anthony W. Norman ; Gerald Litwack |
| title_short | Hormones |
| title_sort | hormones |
| topic | Hormones cabt Hormones Endocrine System Endocrine System Diseases Hormon (DE-588)4025864-6 gnd |
| topic_facet | Hormones Endocrine System Endocrine System Diseases Hormon |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007953613&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT normananthonyw hormones AT litwackgerald hormones |