Applied antisense oligonucleotide technology:
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
New York [u.a.]
Wiley-Liss
1998
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XII, 540 S. Ill., graph. Darst. |
| ISBN: | 0471172790 |
Staff View
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV011754243 | ||
| 003 | DE-604 | ||
| 005 | 19980629 | ||
| 007 | t | ||
| 008 | 980205s1998 ad|| |||| 00||| eng d | ||
| 020 | |a 0471172790 |9 0-471-17279-0 | ||
| 035 | |a (OCoLC)37011242 | ||
| 035 | |a (DE-599)BVBBV011754243 | ||
| 040 | |a DE-604 |b ger |e rakddb | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-355 | ||
| 050 | 0 | |a RM666.A564 | |
| 082 | 0 | |a 615/.31 |2 21 | |
| 084 | |a WG 3450 |0 (DE-625)148549: |2 rvk | ||
| 245 | 1 | 0 | |a Applied antisense oligonucleotide technology |c ed. by C. A. Stein ... |
| 264 | 1 | |a New York [u.a.] |b Wiley-Liss |c 1998 | |
| 300 | |a XII, 540 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 650 | 4 | |a Antisense nucleic acids |x Therapeutic use | |
| 650 | 4 | |a Oligonucleotides, Antisense | |
| 650 | 4 | |a Oligonucleotides, Antisense |x therapeutic use | |
| 650 | 0 | 7 | |a Antisense-Oligonucleotide |0 (DE-588)4371006-2 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Biotechnologie |0 (DE-588)4069491-4 |2 gnd |9 rswk-swf |
| 655 | 7 | |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
| 689 | 0 | 0 | |a Antisense-Oligonucleotide |0 (DE-588)4371006-2 |D s |
| 689 | 0 | 1 | |a Biotechnologie |0 (DE-588)4069491-4 |D s |
| 689 | 0 | |5 DE-604 | |
| 700 | 1 | |a Stein, Cy A. |e Sonstige |4 oth | |
| 856 | 4 | 2 | |m HBZ Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007931885&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-007931885 | ||
Record in the Search Index
| _version_ | 1804126298100989952 |
|---|---|
| adam_text | CONTENTS
PREFACE ix
CONTRIBUTORS x
I CHEMISTRY, OLD AND NEW 1
1 OLIGONUCLEOSIDE METHYLPHOSPHONATES: SYNTHESIS 3
AND PROPERTIES
Paul S. Miller
2 OLIGO(NUCLEOSIDEPHOSPHOROTHIOATE)S 23
Piotr Guga, Maria Koziolkiewicz, Andrzej Okruszek, and Wojciech J. Stec
3 MODIFIED OLIGODEOXYNUCLEOTIDES AS 51
ANTISENSE THERAPEUTICS
Peter H. Seeberger and Marvin H. Caruthers
4 NOVEL CHEMISTRY 73
Karl Heinz Altmann, Bernard Cuenoud, and Peter Von Matt
II OLIGONUCLEOTIDE INTERNALIZATION, 109
MECHANISM OF ACTION, AND
NON SEQUENCE SPECIFICITY
5 CELLULAR UPTAKE AND BIODISTRIBUTION 111
OF OLIGODEOXYNUCLEOTIDES
Basil Hanss, C.A. Stein, and Paul E. Klotman
6 USE OF CATIONIC LIPID COMPLEXES FOR ANTISENSE 129
OLIGONUCLEOTIDE DELIVERY
C. Frank Bennett
7 NONANTISENSE EFFECTS OF ANTISENSE 147
OLIGONUCLEOTIDES
Leonard M. Neckers and Kanak Iyer
8 RIBONUCLEASE H MEDIATED ANTISENSE EFFECTS 161
OF OLIGONUCLEOTIDES AND CONTROLS FOR
ANTISENSE EXPERIMENTS
David M. Tidd
v
Vi CONTENTS
III.A SEQUENCE SPECIFIC INHIBITION OF 173
GENE EXPRESSION
9 THE DEVELOPMENT OF C 5 PROPYNE OLIGONUCLEOTIDES 175
AS INHIBITORS OF GENE FUNCTION
W. Michael Flanagan and Richard W. Wagner
10 THE USE OF ANTISENSE OLIGONUCLEOTIDES TO INHIBIT 193
EXPRESSION OF ISOZYMES OF PROTEIN KINASE C
Nicholas M. Dean, Lemonidis, K., McKay, R., Miraglia, L, Trent, K., and
Pribble, J.P.
11 BCR ABL AS A TARGET FOR ANTISENSE INTERVENTION 207
Stephen G. O Brien and Toon F.C.M. Smetsers
12 THE NF frB TRANSCRIPTION FACTOR 231
Ramaswamy Narayanan
13 DISRUPTION OF THE MAP KINASE SIGNALING PATHWAY 245
USING ANTISENSE OLIGONUCLEOTIDE INHIBITORS
TARGETED TO RAS AND RAF KINASE
Brett P. Monia
14 PROTEIN KINASE A DIRECTED ANTISENSE BLOCKADE 263
OF CANCER GROWTH: SINGLE GENE BASED
THERAPEUTIC APPROACH
Yoon S. Cho Chung
15 USE OF ANTISENSE OLIGONUCLEOTIDES IN THE CENTRAL 283
NERVOUS SYSTEM: WHY SUCH SUCCESS?
Margaret M. McCarthy
III.B APPLIED ANTISENSE OLIGONUCLEOTIDE 297
THERAPEUTICS
16 PERTURBING HEMATOPOIETIC CELL GENE EXPRESSION 299
WITH OLIGODEOXYNUCLEOTIDES: RESEARCH AND
CLINICAL APPLICATIONS
Alan M. Gewirtz and Mariusz Z. Ratajczak
17 BCL2 317
Burkhard Jansen and Bob D. Brown
18 BIOLOGICAL ACTIVITY OF GUANOSINE 335
QUARTET FORMING OLIGONUCLEOTIDES
Robert F. Rando and Michael E. Hogan
CONTENTS Vii
IV OLIGONUCLEOTIDES AS ANTI HIV AGENTS 353
19 PERSPECTIVES ON ANTISENSE TECHNOLOGY 355
AGAINST HIV
Jay E. Gee, Amelie Benoit de Coignac, Ian Robbins, and Bernard LeBleu
20 IN VIVO PHARMACOKINETICS OF OLIGONUCLEOTIDES 365
Sudhir Agrawal
21 EARLY CLINICAL TRIALS WITH GEM 91, 387
A SYSTEMIC OLIGODEOXYNUCLEOTIDE
R. Russell Martin
V THERAPEUTIC OLIGONUCLEOTIDE DATA BASE: 395
PHARMACOKINETICS, IMMUNE STIMULATION, AND
USE AS ANTIRESTENOTIC AGENTS
22 ANTISENSE THERAPY TO INHIBIT 397
ANGIOPLASTY RESTENOSIS
Leroy E. Rabbani and Weizheng Wang
23 PHARMACOKINETICS OF OLIGONUCLEOTIDES: A REVIEW 407
OF CURRENT KNOWLEDGE AND ISSUES FOR THE FUTURE
Thomas L. Wallace and Paul A. Cossum
24 LEUKOCYTE STIMULATION BY OLIGODEOXYNUCLEOTIDES 431
Arthur M. Krieg
VI SELECTED OLIGODEOXYNUCLEOTIDE
DEVELOPMENTAL TOPICS: SPLICING 449
AND TRIPLEXES
25 MODIFICATION OF ALTERNATIVE SPLICING OF PRE mRNA 451
BY ANTISENSE OLIGONUCLEOTIDES
Ryszard Kole
26 GENE TARGETED TRIPLE HELIX FORMING 471
OLIGONUCLEOTIDES
Fedor Svinarchuk and Claude Malvy
27 TRIPLEX FORMING OLIGONUCLEOTIDES FOR GENETIC 487
MANIPULATION: AN ALTERNATIVE VIEW
A. Fawad Faruqi and Peter M. Glazer
ViM CONTENTS
VII A REVIEW OF RIBOZYME TECHNOLOGY 509
28 THERAPEUTIC RIBOZYMES: PRINCIPLES, APPLICATIONS, 511
AND PROBLEMS
John J. Rossi
INDEX 527
|
| any_adam_object | 1 |
| building | Verbundindex |
| bvnumber | BV011754243 |
| callnumber-first | R - Medicine |
| callnumber-label | RM666 |
| callnumber-raw | RM666.A564 |
| callnumber-search | RM666.A564 |
| callnumber-sort | RM 3666 A564 |
| callnumber-subject | RM - Therapeutics and Pharmacology |
| classification_rvk | WG 3450 |
| ctrlnum | (OCoLC)37011242 (DE-599)BVBBV011754243 |
| dewey-full | 615/.31 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615/.31 |
| dewey-search | 615/.31 |
| dewey-sort | 3615 231 |
| dewey-tens | 610 - Medicine and health |
| discipline | Biologie Medizin |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01582nam a2200409 c 4500</leader><controlfield tag="001">BV011754243</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">19980629 </controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">980205s1998 ad|| |||| 00||| eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">0471172790</subfield><subfield code="9">0-471-17279-0</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)37011242</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV011754243</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakddb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RM666.A564</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">615/.31</subfield><subfield code="2">21</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WG 3450</subfield><subfield code="0">(DE-625)148549:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Applied antisense oligonucleotide technology</subfield><subfield code="c">ed. by C. A. Stein ...</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">New York [u.a.]</subfield><subfield code="b">Wiley-Liss</subfield><subfield code="c">1998</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">XII, 540 S.</subfield><subfield code="b">Ill., graph. Darst.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Antisense nucleic acids</subfield><subfield code="x">Therapeutic use</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Oligonucleotides, Antisense</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Oligonucleotides, Antisense</subfield><subfield code="x">therapeutic use</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Antisense-Oligonucleotide</subfield><subfield code="0">(DE-588)4371006-2</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Biotechnologie</subfield><subfield code="0">(DE-588)4069491-4</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="0">(DE-588)4143413-4</subfield><subfield code="a">Aufsatzsammlung</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Antisense-Oligonucleotide</subfield><subfield code="0">(DE-588)4371006-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Biotechnologie</subfield><subfield code="0">(DE-588)4069491-4</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Stein, Cy A.</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">HBZ Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007931885&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-007931885</subfield></datafield></record></collection> |
| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV011754243 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:15:14Z |
| institution | BVB |
| isbn | 0471172790 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-007931885 |
| oclc_num | 37011242 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR |
| owner_facet | DE-355 DE-BY-UBR |
| physical | XII, 540 S. Ill., graph. Darst. |
| publishDate | 1998 |
| publishDateSearch | 1998 |
| publishDateSort | 1998 |
| publisher | Wiley-Liss |
| record_format | marc |
| spelling | Applied antisense oligonucleotide technology ed. by C. A. Stein ... New York [u.a.] Wiley-Liss 1998 XII, 540 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Antisense nucleic acids Therapeutic use Oligonucleotides, Antisense Oligonucleotides, Antisense therapeutic use Antisense-Oligonucleotide (DE-588)4371006-2 gnd rswk-swf Biotechnologie (DE-588)4069491-4 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Antisense-Oligonucleotide (DE-588)4371006-2 s Biotechnologie (DE-588)4069491-4 s DE-604 Stein, Cy A. Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007931885&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Applied antisense oligonucleotide technology Antisense nucleic acids Therapeutic use Oligonucleotides, Antisense Oligonucleotides, Antisense therapeutic use Antisense-Oligonucleotide (DE-588)4371006-2 gnd Biotechnologie (DE-588)4069491-4 gnd |
| subject_GND | (DE-588)4371006-2 (DE-588)4069491-4 (DE-588)4143413-4 |
| title | Applied antisense oligonucleotide technology |
| title_auth | Applied antisense oligonucleotide technology |
| title_exact_search | Applied antisense oligonucleotide technology |
| title_full | Applied antisense oligonucleotide technology ed. by C. A. Stein ... |
| title_fullStr | Applied antisense oligonucleotide technology ed. by C. A. Stein ... |
| title_full_unstemmed | Applied antisense oligonucleotide technology ed. by C. A. Stein ... |
| title_short | Applied antisense oligonucleotide technology |
| title_sort | applied antisense oligonucleotide technology |
| topic | Antisense nucleic acids Therapeutic use Oligonucleotides, Antisense Oligonucleotides, Antisense therapeutic use Antisense-Oligonucleotide (DE-588)4371006-2 gnd Biotechnologie (DE-588)4069491-4 gnd |
| topic_facet | Antisense nucleic acids Therapeutic use Oligonucleotides, Antisense Oligonucleotides, Antisense therapeutic use Antisense-Oligonucleotide Biotechnologie Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007931885&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT steincya appliedantisenseoligonucleotidetechnology |