Clinical management of bladder cancer:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
London [u.a.]
Arnold
1999
|
| Ausgabe: | 1. publ. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XVI, 384 S. Ill., graph. Darst. |
| ISBN: | 0340740922 |
Internformat
MARC
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| 245 | 1 | 0 | |a Clinical management of bladder cancer |c ed. by Reginald R. Hall |
| 250 | |a 1. publ. | ||
| 264 | 1 | |a London [u.a.] |b Arnold |c 1999 | |
| 300 | |a XVI, 384 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 650 | 4 | |a Bladder |x Cancer | |
| 650 | 4 | |a Urinary Bladder Neoplasms |x diagnosis | |
| 650 | 4 | |a Urinary Bladder Neoplasms |x pathology | |
| 650 | 0 | 7 | |a Therapie |0 (DE-588)4059798-2 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Blasenkrebs |0 (DE-588)4007032-3 |2 gnd |9 rswk-swf |
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| 999 | |a oai:aleph.bib-bvb.de:BVB01-007866247 | ||
Datensatz im Suchindex
| _version_ | 1804126203975565312 |
|---|---|
| adam_text | Contents
List of contributors xi
Preface xv
Acknowledgements xvi
1. The diagnosis of bladder cancer 1
Reginald R. Hall
Introduction 1
Haematuria 1
Cystoscopy 5
Imaging of the upper urinary tract 5
Urine cytology and other diagnostic tests 6
Mucosal biopsies 10
Screening for bladder cancer 13
References 15
Commentary 21
Harry W. Herr
Urine cytology 21
Telomerase 22
Mucosal biopsies 22
TCC in the prostatic urethra 22
Bladder cancer screening 22
Commentary references 23
2. Histopathology of urothelial cancer: consensus or controversy? 25
Mary C. Robinson and Reginald R. Hall
Papilloma or carcinoma? 26
Tumour grade 28
Inverted transitional cell papilloma 33
Problems of histopathological staging 35
Carcinoma in situ (CIS) 43
Variants of transitional cell carcinoma 46
Squamous epithelial tumours 48
vi Contents
Glandular epithelial tumours 51
Small (oat) cell carcinoma 53
Review pathology 55
References 57
3. Transurethral resection and staging of bladder cancer 67
Reginald R. Hall
Endoscopic assessment and transurethral resection 67
Significance of complete TUR for T2 and T3 cancers 73
Full thickness TUR 75
Tumour staging 79
Summary 88
References 88
Commentary 95
Harry W. Herr
Complete TUR 95
TUR biopsy 95
Staging 96
Repeat TUR 96
Commentary references 96
4. Prognostic factors, treatment options and follow up of Ta and Tl
bladder tumours 97
Philip H. Smith and Reginald R. Hall
Introduction 97
Prognostic factors at diagnosis 98
Prognostic factors in the patient with recurrent tumour 101
Treatment options 102
Chemoresection of marker tumours 106
Other intravesical therapy 108
Oral treatment for Ta Tl tumours and CIS of the bladder 108
Cytotoxic chemotherapy or BCG? 109
Frequency of follow up 111
References 113
Commentary 119
Donald L. Lamm and Peter R. Auriemma
Prognostic factors 119
Intravesical treatment 120
Intravesical BCG versus chemotherapy 120
Oral prophylaxis 122
Follow up 122
Commentary references 123
Contents vii
5. Bacillus Calmette Guerin (BCG) for transitional cell carcinoma
of the bladder 125
Adrian D. P. van der Meijden
Introduction 125
Route of administration 126
The best BCG strain 127
Dose of BCG 128
Maintenance or booster therapy 129
Adverse reactions to BCG 130
Prevention of adverse effects 133
Treatment of side effects 134
Further improvement of BCG therapy 136
How does BCG work? 137
BCG or intravesical chemotherapy? 138
Summary 139
References 139
Commentary 144
Donald L. Lamm
Percutaneous BCG 144
Dose and schedule of BCG 145
Side effects 145
Commentary references 146
6. Carcinoma in situ 149
Gerhard Jakse
Introduction 149
Clinical definition and behaviour of CIS 149
Symptoms and diagnosis 151
Treatment 154
Cystectomy 161
Assessment of response and follow up 162
References 163
7. Cystectomy, bladder reconstruction, urinary diversion and
stomatherapy 171
William H. Turner and Urs E. Studer
Cystectomy 172
Urinary diversion, bladder reconstruction and stomatherapy 178
Incontinent urinary diversion 180
Continent urinary diversion 181
Orthotopic bladder substitution 183
Morbidity of conduits, continent diversions and bladder substitutes 185
Quality of life and stomatherapy 191
viii Contents
Conclusions 192
References 193
Commentary 207
Donald G. Skinner
Indications for cystectomy 207
Cystectomy: standard treatment for invasive bladder cancer 207
Pelvic lymphadenectomy 208
Molecular and genetic studies 208
Bladder reconstruction 209
Continence 209
Conclusion 210
Commentary references 210
8. Radiotherapy for bladder cancer 213
Mary K. Gospodarowicz, Padraig Warde and Rob G. Bristow
Introduction 213
Patient selection 216
Selection of the overall treatment plan 217
Radiotherapy treatment delivery 220
Post treatment management 223
Possible cellular and molecular approaches to improving the
results of bladder radiation treatment 224
Summary 228
References 229
Commentary 1 236
Alan Horwich
Commentary references 238
Commentary 2 239
Luc M. F. Moonen
Brachytherapy 239
Commentary references 240
9. Neoadjuvant and adjuvant chemotherapy in the treatment of
muscle invasive bladder cancer 241
Christopher J. Logothetis
Evidence for the use of adjunctive combination chemotherapy in
urothelial tumours 242
Adjuvant CISCA chemotherapy in patients with resected urothelial
cancer 243
Optimal integration of chemotherapy and surgery for locally
advanced bladder cancer 244
Early stage invasive bladder cancer 246
Contents ix
Summary 247
References 247
Commentary 249
Mahesh K. B. Parmar and Sarah Burdett
Neoadjuvant chemotherapy 250
Adjuvant chemotherapy 254
Conclusion 258
Commentary references 260
Appendix 1 263
10. Bladder preservation in muscle invasive bladder cancer 265
/. Trevor Roberts
Non radiotherapeutic approaches to bladder preservation 266
Transurethral resection 266
Partial or segmental cystectomy 270
Systemic chemotherapy in regionally advanced bladder cancer 272
Discussion 279
References 283
Commentary 288
Saad Khoury
11. Systemic chemotherapy for metastatic cancer of the uro epithelial
tract 289
Derek Raghavan
Biology of metastatic urothelial cancer: implications for the results of
treatment 289
Single agent chemotherapy 291
Combination regimens 293
Dose intensity 294
New agents and approaches 296
Palliative chemotherapy: an oxymoron? 297
Treatment of the asymptomatic patient: a dilemma 299
Resistance to chemotherapy: prediction and intervention 300
Summary and future prospects 303
References 304
12. Clinical trials and statistics in bladder cancer 313
Richard J. Sylvester
Phase I trials 313
Phase II trials 315
Phase III trials 320
Randomization 320
x Contents
Stratification 321
Sample size calculation 322
Design and analysis of prophylactic superficial (Ta Tl) bladder
cancer trials 324
Design and analysis of bladder carcinoma in situ trials 327
Design and analysis of muscle invasive bladder cancer trials 328
Design and analysis of metastatic bladder cancer trials 328
Conclusion 330
References 330
13. Smoking and bladder cancer 335
Suzanne Cholerton and Reginald R. Hall
Quantity of tobacco 337
Smoking cessation 338
Type of tobacco 339
Smoking and histological grade, stage and recurrence of bladder
cancer 339
Constituents of tobacco smoke 340
In vivo studies 345
In vitro studies 346
Genetic polymorphisms in xenobiotic metabolism and susceptibility
to bladder cancer 347
Summary 351
References 352
Commentary 363
Karlheinz Kurth
Commentary references 364
14. Talking with patients about bladder cancer 365
Reginald R. Hall, Margaret M. Charlton and Patricia Ongena
The physician 366
The patient 368
Ta Tl bladder cancer 371
Muscle invasive bladder cancer 372
Randomized clinical trials 376
Summary 377
References 378
Index 379
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| spelling | Clinical management of bladder cancer ed. by Reginald R. Hall 1. publ. London [u.a.] Arnold 1999 XVI, 384 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Bladder Cancer Urinary Bladder Neoplasms diagnosis Urinary Bladder Neoplasms pathology Therapie (DE-588)4059798-2 gnd rswk-swf Blasenkrebs (DE-588)4007032-3 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Blasenkrebs (DE-588)4007032-3 s Therapie (DE-588)4059798-2 s DE-604 Hall, Reginald R. Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007866247&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Clinical management of bladder cancer Bladder Cancer Urinary Bladder Neoplasms diagnosis Urinary Bladder Neoplasms pathology Therapie (DE-588)4059798-2 gnd Blasenkrebs (DE-588)4007032-3 gnd |
| subject_GND | (DE-588)4059798-2 (DE-588)4007032-3 (DE-588)4143413-4 |
| title | Clinical management of bladder cancer |
| title_auth | Clinical management of bladder cancer |
| title_exact_search | Clinical management of bladder cancer |
| title_full | Clinical management of bladder cancer ed. by Reginald R. Hall |
| title_fullStr | Clinical management of bladder cancer ed. by Reginald R. Hall |
| title_full_unstemmed | Clinical management of bladder cancer ed. by Reginald R. Hall |
| title_short | Clinical management of bladder cancer |
| title_sort | clinical management of bladder cancer |
| topic | Bladder Cancer Urinary Bladder Neoplasms diagnosis Urinary Bladder Neoplasms pathology Therapie (DE-588)4059798-2 gnd Blasenkrebs (DE-588)4007032-3 gnd |
| topic_facet | Bladder Cancer Urinary Bladder Neoplasms diagnosis Urinary Bladder Neoplasms pathology Therapie Blasenkrebs Aufsatzsammlung |
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