Pharmacology and brain rehabilitation:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Philadelphia [u.a.]
Saunders
1997
|
| Schriftenreihe: | Physical medicine and rehabilitation clinics of North America
8,4 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIV S., S. 605 - 857 Ill., graph. Darst. |
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| 650 | 4 | |a Brain Injuries |x drug therapy | |
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Datensatz im Suchindex
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| adam_text | PHARMACOLOGY AND BRAIN REHABILITATION
CONTENTS
Foreword xi
George H. Kraft
Preface xiii
Lawrence J. Horn
Principles of Neurochemistry and Neuropharmacology 605
Elie Elovic, MD, and Terri Antoinette, MHSA, RNC, CRRN
A rational approach to postinjury pharmacologic treatment relies
on the formation of theories and models. The limitations of the
knowledge base must lead to the integration of basic scientific
discoveries into clinical decision making, thereby increasing un¬
derstanding of normal and pathologic states. This will lead to the
development of more rationally based pharmacologic approaches
to modify neurotransmitters and the neuromodulatory activity of
damaged neuronal systems.
Drugs in the Management of Acute Traumatic Brain Injury 629
Ramesh Raghupathi, PhD, and Tracy K. Mclntosh, PhD
It is believed that traumatic brain injury is the result of both
direct and indirect injury, and that secondary injury develops
over a period of hours to days to weeks following brain trauma.
Clinical, radiologic, and pathologic analyses suggest that brain
damage after head injury may be the result of abnormal neuro
chemical activity. Characterization of the pathologic neurochemi
cal cascade following traumatic brain injury provides an opportu¬
nity for the development of therapeutic paradigms designed in
PHYSICAL MEDICINE AND REHABILITATION
CLINICS OF NORTH AMERICA
VOLUME 8 • NUMBER 4 • NOVEMBER 1997 V
response to the pathophysiologic activity of these autodestructive
factors, thereby leading to prevention or attenuation of cerebro
vascular, metabolic, and histologic damage.
Clinical Neuropharmacology of Behavioral Recovery
Following Brain Injury 651
Robert L. Harmon, MD, MS, and Michael G. Boyeson, PhD
Of the many models that have been offered to explain recovery
of particular behaviors after various types of brain injury, all are
based on the observation that a significant amount of behavioral
recovery occurs in the absence of complete regrowth of brain
tissue. Altering biochemical events, such as controlling the mas¬
sive release of neurotransmitters or reducing edema and lactic
acid after brain injury, may provide more specific methods to
intercede in the injury process before the damage has progressed
to its final, more permanent state.
Drugs for Medical Concerns in Traumatic Brain Injury 667
Flora M. Hammond, MD, and Kertia L. Black, MD
Traumatic brain injury (TBI) poses unique physiologic concerns
and demands new treatment strategies. The effects of medications
administered to the individual with TBI may differ vastly from
other patient populations. This article reviews the role of medica¬
tions salient to the medical and rehabilitative disturbances com¬
monly encountered with TBI: venous thromboembolism, hetero
topic ossification, gastric motility, peptic ulcer disease, genito¬
urinary function, and skin integrity.
Drugs for Pain Management 695
Shelley A. Killen, MD, and Elizabeth Huntoon, MD
Pain is always subjective in its nature and, at times, may be tied
much more closely to psychologic stimuli than to actual physical
stimuli. Pain in a patient with brain injury is often more difficult
to treat due to altered cognition, perception, and physiologic
response to medication. In this article, many different medications
are discussed with respect to their use as analgesics, adjuvant
analgesics, and their side effect profile.
Pharmacologic Management of Spasticity in Adults with
Brain Injury 707
Gerard E. Francisco, MD, and Cindy B. Ivanhoe, MD
Spasticity is one of the most devastating musculoskeletal sequelae
of brain injury because it leads to functional impairments that
augment disability. In spite of recent therapeutic advances, spas¬
ticity remains one of the most challenging impairments encoun¬
tered by physiatrists. When treating brain injured patients, drug
side effects become a crucial consideration in determining appro
Vi CONTENTS
priate treatment because many of the individuals cannot afford
the known sedative and adverse cognitive effects of many
spasmolytic medications. For this and several other reasons, spas
ticity management in brain injury is complex and requires certain
considerations to increase the likelihood of therapeutic success.
Drugs for the Management of Dystonia and Movement
Disorders 733
Cindy B. Ivanhoe, MD, and Gerard E. Francisco, MD
Of all pharmacologic methods used to treat movement disorders
following traumatic brain injury, none are without side effects.
When deciding to treat a movement disorder, weigh the potential
risks and benefits. If pharmacologic management is deemed nec¬
essary, an attempt should be made periodically to wean the
patient from the medications, because a spontaneous remission
may occur.
Psychopharmacologic Treatment for Affective Disorders
after Traumatic Brain Injury 743
M. Elizabeth Sandel, MD, and Alexander S. Zwil, MD
The spectrum of psychologic, social, and behavioral effects of
traumatic brain injury often represents the most significant im¬
pairments for survivors and their families in the weeks, months,
and years after the initial trauma. This article outlines the criteria
for diagnosis of two common disorders in the TBI population:
depression and bipolar disorder. Evidence for a neuropathologic
basis for these disorders is then reviewed.
Drugs for Management of Acute and Chronic Behavioral
Disorders 763
David R. Wiercisiewski, MD, and James T. McDeavitt, MD
Behavioral disorders are frequently the most profoundly disa¬
bling sequelae of traumatic brain injury. In this article, basic
behavioral syndromes are reviewed, including posttraumatic agi¬
tation, anxiety disorder, panic attacks, posttraumatic stress disor¬
der, obsessive compulsive disorder, hyperphagia, and pathologic
crying. Pharmacologic treatment options for each are discussed.
Medications to Enhance Cognitive Functioning 781
W. Jerry Mysiw, MD, and Daniel M. Clinchot, MD
Cognitive and behavioral abnormalities after traumatic brain
injury (TBI) are reported by survivors as more disabling than the
residual physical defects. The TBI literature has begun to address
a number of these mood and behavioral disorders. The medical
management of the many cognitive impairments frequently en¬
countered after TBI, however, has been virtually ignored in the
CONTENTS vii
rehabilitation literature, and pharmacologic treatment options for
the cognitive sequelae of TBI remain limited.
Drugs for Management of Sleep Disorders 801
Flora M. Hammond, MD, and Ross D. Zafonte, DO
Sleep disorders of various causes are common following trau¬
matic brain injury (TBI). Disturbed sleep may profoundly affect
brain injury survivors arousal, cognition, behavior, and function.
Research studies are needed regarding the use of pharmacologic
agents for treating disordered sleep associated with TBI. The
information in this article incorporates current knowledge about
the pharmacology of normal and disordered sleep with that pos¬
tulated about neuropharmacology in TBI.
Management of Neuroendocrine Disorders after Brain
Injury 827
Deborah G. Stewart, MD, and David X. Cifu, MD
Endocrine complications can occur in approximately 25% of indi¬
viduals who sustain a moderate or severe head injury. This article
emphasizes a practical approach to management recommenda¬
tions for neuroendocrine disorders in the rehabilitation setting.
One must be aware of the possibility of endocrine and autonomic
dysfunction, develop a plan for evaluation and treatment, and
monitor the patient s progress.
Cumulative Index 843
Subscription Information Inside back cover
viii CONTENTS
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| spelling | Pharmacology and brain rehabilitation Lawrence J. Horn Philadelphia [u.a.] Saunders 1997 XIV S., S. 605 - 857 Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Physical medicine and rehabilitation clinics of North America 8,4 Neuropharmacologie Traumatismes de l'encéphale - Rééducation et réadaptation Brain Injuries drug therapy Brain Injuries rehabilitation Brain Wounds and injuries Patients Rehabilitation Medical rehabilitation Neuropharmacology Hirnschädigung (DE-588)4072519-4 gnd rswk-swf Hirnfunktionsstörung (DE-588)4133771-2 gnd rswk-swf Pharmakotherapie (DE-588)4076066-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Hirnschädigung (DE-588)4072519-4 s Pharmakotherapie (DE-588)4076066-2 s DE-604 Hirnfunktionsstörung (DE-588)4133771-2 s Horn, Lawrence J. Sonstige oth Physical medicine and rehabilitation clinics of North America 8,4 (DE-604)BV004322117 8,4 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007855013&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Pharmacology and brain rehabilitation Physical medicine and rehabilitation clinics of North America Neuropharmacologie Traumatismes de l'encéphale - Rééducation et réadaptation Brain Injuries drug therapy Brain Injuries rehabilitation Brain Wounds and injuries Patients Rehabilitation Medical rehabilitation Neuropharmacology Hirnschädigung (DE-588)4072519-4 gnd Hirnfunktionsstörung (DE-588)4133771-2 gnd Pharmakotherapie (DE-588)4076066-2 gnd |
| subject_GND | (DE-588)4072519-4 (DE-588)4133771-2 (DE-588)4076066-2 (DE-588)4143413-4 |
| title | Pharmacology and brain rehabilitation |
| title_auth | Pharmacology and brain rehabilitation |
| title_exact_search | Pharmacology and brain rehabilitation |
| title_full | Pharmacology and brain rehabilitation Lawrence J. Horn |
| title_fullStr | Pharmacology and brain rehabilitation Lawrence J. Horn |
| title_full_unstemmed | Pharmacology and brain rehabilitation Lawrence J. Horn |
| title_short | Pharmacology and brain rehabilitation |
| title_sort | pharmacology and brain rehabilitation |
| topic | Neuropharmacologie Traumatismes de l'encéphale - Rééducation et réadaptation Brain Injuries drug therapy Brain Injuries rehabilitation Brain Wounds and injuries Patients Rehabilitation Medical rehabilitation Neuropharmacology Hirnschädigung (DE-588)4072519-4 gnd Hirnfunktionsstörung (DE-588)4133771-2 gnd Pharmakotherapie (DE-588)4076066-2 gnd |
| topic_facet | Neuropharmacologie Traumatismes de l'encéphale - Rééducation et réadaptation Brain Injuries drug therapy Brain Injuries rehabilitation Brain Wounds and injuries Patients Rehabilitation Medical rehabilitation Neuropharmacology Hirnschädigung Hirnfunktionsstörung Pharmakotherapie Aufsatzsammlung |
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