New therapeutic agents in thrombosis and thrombolysis:
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
New York [u.a.]
Dekker
1997
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XIV, 681 S. Ill., graph. Darst. |
| ISBN: | 082479866X |
Staff View
MARC
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| 245 | 1 | 0 | |a New therapeutic agents in thrombosis and thrombolysis |c ed. by Arthur A. Sasahara ... |
| 264 | 1 | |a New York [u.a.] |b Dekker |c 1997 | |
| 300 | |a XIV, 681 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 650 | 7 | |a Fibrinolytica |2 gtt | |
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| 650 | 4 | |a Fibrinolytic Agents | |
| 650 | 4 | |a Fibrinolytic agents | |
| 650 | 4 | |a Hemostasis |x drug effects | |
| 650 | 4 | |a Thrombolytic Therapy | |
| 650 | 4 | |a Thrombolytic therapy | |
| 650 | 4 | |a Thrombosis | |
| 650 | 4 | |a Thrombosis |x drug therapy | |
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Record in the Search Index
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|---|---|
| adam_text | Contents
Preface Hi
Contributors ix
PARTI. OVERVIEWS
1. Overview of Hemostasis and Fibrinolysis 1
Joseph Loscalzo and Andrew I. Schafer
2. A Survey of Animal Models to Develop New
and Novel Antithrombotic Agents 9
Walter Jeske, Demetra D. Callas, Brigitte Kaiser, and Jawed Fareed
3. Experimental Strategies for Assessing Antithrombotic Benefits
and Hemorrhagic Risks of Novel Antithrombotic Agents 29
Laurence A. Marker and Stephen R. Hanson
4. Design Issues in Clinical Trials of Thrombolytic and Antithrombotic Agents 49
Dina S. Stolman, Jay P. Siegel, Marc K. Walton, R. Dwaine Rieves,
and Victor F. C. Raczkowski
PART II. NEW HEPARINS, THROMBIN INHIBITORS, AND OTHER NEW AGENTS
5. Overview of New Developments in Heparins, Thrombin Inhibitors,
and Other New and Novel Agents 77
Jeffrey I. Weitz and Jack Hirsh
6. Low Molecular Weight Heparins: Biochemistry and Pharmacology 87
Meyer Michel Samama and Pierre Claude Desnoyers
7. Low Molecular Weight Heparins: Prophylaxis of Venous Thrombosis 103
Vijay Vir Kakkar
8. Low Molecular Weight Heparins: Treatment of Venous Thromboembolism 129
Philomeen M. M. Kuijer, Martin H. Prins, and Harry Roger Btiller
v
vi Contents
9. Direct Thrombin Inhibitors: Active Site Inhibitors of Thrombin 143
Jules A. Shafer
10. Direct Thrombin Inhibitors in Venous Thromboembolism 159
Mark A. Crowther and Jeffrey S. Ginsberg
11. Direct Thrombin Inhibitors in Arterial Thrombosis 169
Bernard Rudolph Erickson and Eric Jeffrey Topol
12. Direct Thrombin Inhibitors: Hirulog 191
John M. Maraganore
13. Modulation of the Protein C Pathway as a Therapy for Thrombosis 209
Charles T. Esrnon
14. Tissue Factor Pathway Inhibitor 225
Thomas J. Girard !
15. Direct Factor Xa Inhibitors 261
George P. Vlasuk
PART III. NEW ANTIPLATELET AGENTS
16. Overview of Inhibition of Platelet Functions 285
James T. Willerson and Claude R. Benedict
17. Pharmacology and Clinical Development of Abciximab (c7E3 Fab, ReoPro):
A Monoclonal Antibody Inhibitor of GPIIb/IIIa and otvfc 291
Robert E. Jordan, Mary Ann Mascelli, Marian T. Nakada,
and Harlan F. Weisman
18. Clinical Use of a Monoclonal Antibody to the Platelet Glycoprotein
Ilb/IIIa Receptor 315
James J. Ferguson and James T. Willerson
19. Integrilin™: Synthetic Peptides Against the Platelet Glycoprotein
Ilb/IIIa Receptor 333
Barbara E. Tardiff, Julie M. Miller, Robert A. Harrington, James E. Tcheng,
and Robert M. Califf
20. Tirofiban, a Nonpeptide Inhibitor of the Platelet Glycoprotein
Ilb/IIIA Receptor 355
Lawrence I. Deckelbaum, Frederic L. Sax, and William Grossman
21. Aurin Tricarboxylic Acid: Inhibitor of von Willebrand Factor
Attachment to Platelet GPIb 367
Martin D. Phillips and Joel L. Moake
Contents vii
22. Antagonism of Platelet Glycoprotein Ib Receptors: Protective Effects
in Injured Coronary Arteries 385
James T. Willerson
23. Oxygen Derived Free Radicals and Arterial Thrombosis 407
Paolo Golino
24. Platelet Procoagulant Activity 419
Permual Thiagarajan and Claude R. Benedict
25. Development of Unstable Angina and Myocardial Infarction:
Importance of Platelets, Platelet and Endothelium Derived Mediators,
and Monocytes/Macrophages in Thrombosis, Vasoconstriction,
and Neointimal Proliferation 435
James T. Willerson
PART IV. NEW THROMBOLYTIC AGENTS
26. Introduction to the Section on New Thrombolytic Agents 449
Marc Verstraete
27. Animal Models to Assess the Safety and Efficacy
of Thrombolytic Agents 451
Jean Marie Stassen
28. Biochemistry, Pharmacology, and Initial Clinical Experience
with TNK tPA 475
E. R. McCluskey, Bruce A. Keyt, Canio J. Refino, Nishit B. Modi,
Thomas F. Zioncheck, Jeanine L. Bussiere, and Ted W. Love
29. Clinical and Preclinical Profile of the Novel Recombinant
Plasminogen Activator Reteplase 495
Ulrich Martin
30. Recombinant Urokinase (r UK): Biochemistry, Pharmacology,
and Clinical Experience 513
R. Bruce Credo, Sandra E. Burke, Walter M. Barker, Gregory A. Schulz,
Jochen M. Felbel, Jack Henkin, and Arthur A. Sasahara
31. Pro urokinase: History, Mechanisms of Action,
and Clinical Development 539
Victor Gurewich
32. Recombinant Glycosylated Pro urokinase: Biochemistry, Pharmacology,
and Early Clinical Experience 561
R. Bruce Credo, Sandra E. Burke, Walter M. Barker, Esther M. Villiard,
Janet M. Sweeny, John C. Sobolski, Jack Henkin, W. Douglas Weaver,
Joseph R. Hartmann, and Arthur A. Sasahara
viii Contents
33. Recombinant Staphylokinase for Thrombolytic Therapy 591
Steven Vanderschueren, Frans Van de Werf, and Desire Collen
34. Desmodus rotundus (Vampire Bat) Plasminogen Activator DSPAoti:
A Superior Thrombolytic Created by Evolution 603
Wolf Dieter Schleuning, Akhileshwar Bhargava, and Peter Donner
35. Antibody Targeting: A Strategy for Improving Thrombolytic Therapy 625
EdgarHaber
36. Thrombolytic Agents in Development 639
Marc Verstraete and Fedor Bachmann
Index 649
i
I
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| spelling | New therapeutic agents in thrombosis and thrombolysis ed. by Arthur A. Sasahara ... New York [u.a.] Dekker 1997 XIV, 681 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Fibrinolytica gtt Fibrinolytiques ram Thrombose - Chimiothérapie ram Trombose gtt Fibrinolytic Agents Fibrinolytic agents Hemostasis drug effects Thrombolytic Therapy Thrombolytic therapy Thrombosis Thrombosis drug therapy Fibrinolyse (DE-588)4017040-8 gnd rswk-swf Fibrinolysetherapie (DE-588)4212438-4 gnd rswk-swf Thrombose (DE-588)4059963-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Fibirinolytikum gnd rswk-swf Thrombose (DE-588)4059963-2 s Fibrinolyse (DE-588)4017040-8 s DE-604 Fibirinolytikum f Fibrinolysetherapie (DE-588)4212438-4 s Sasahara, Arthur A. Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007711503&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | New therapeutic agents in thrombosis and thrombolysis Fibrinolytica gtt Fibrinolytiques ram Thrombose - Chimiothérapie ram Trombose gtt Fibrinolytic Agents Fibrinolytic agents Hemostasis drug effects Thrombolytic Therapy Thrombolytic therapy Thrombosis Thrombosis drug therapy Fibrinolyse (DE-588)4017040-8 gnd Fibrinolysetherapie (DE-588)4212438-4 gnd Thrombose (DE-588)4059963-2 gnd |
| subject_GND | (DE-588)4017040-8 (DE-588)4212438-4 (DE-588)4059963-2 (DE-588)4143413-4 |
| title | New therapeutic agents in thrombosis and thrombolysis |
| title_auth | New therapeutic agents in thrombosis and thrombolysis |
| title_exact_search | New therapeutic agents in thrombosis and thrombolysis |
| title_full | New therapeutic agents in thrombosis and thrombolysis ed. by Arthur A. Sasahara ... |
| title_fullStr | New therapeutic agents in thrombosis and thrombolysis ed. by Arthur A. Sasahara ... |
| title_full_unstemmed | New therapeutic agents in thrombosis and thrombolysis ed. by Arthur A. Sasahara ... |
| title_short | New therapeutic agents in thrombosis and thrombolysis |
| title_sort | new therapeutic agents in thrombosis and thrombolysis |
| topic | Fibrinolytica gtt Fibrinolytiques ram Thrombose - Chimiothérapie ram Trombose gtt Fibrinolytic Agents Fibrinolytic agents Hemostasis drug effects Thrombolytic Therapy Thrombolytic therapy Thrombosis Thrombosis drug therapy Fibrinolyse (DE-588)4017040-8 gnd Fibrinolysetherapie (DE-588)4212438-4 gnd Thrombose (DE-588)4059963-2 gnd |
| topic_facet | Fibrinolytica Fibrinolytiques Thrombose - Chimiothérapie Trombose Fibrinolytic Agents Fibrinolytic agents Hemostasis drug effects Thrombolytic Therapy Thrombolytic therapy Thrombosis Thrombosis drug therapy Fibrinolyse Fibrinolysetherapie Thrombose Aufsatzsammlung Fibirinolytikum |
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