Leukocyte integrins: structure, expression and function
Saved in:
| Main Author: | |
|---|---|
| Format: | Book |
| Language: | German |
| Published: |
New York [u.a.]
Springer
1996
Austin Landes |
| Series: | Molecular biology intelligence unit
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | Literaturverz. S. 145 - 206 |
| Physical Description: | 208 S. Ill., graph. Darst. |
| ISBN: | 3540613536 |
Staff View
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Record in the Search Index
| _version_ | 1804125582264369152 |
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| adam_text | IMAGE 1
CONTENTS
1. LEUKOCYTES AND CELL ADHESION MOLECULES 1
THE MOBILE CELLS OF THE IMMUNE SYSTEM 1
PHAGOCYTES 4
LYMPHOID CELLS 6
NATURAL KILLER CELLS 9
DENDRITIC CELL SYSTEM 9
CELL ADHESION MOLECULES 10
2. INTEGRINS: COMMON FUNCTIONAL AND STRUCTURAL ASPECTS 17 DISCOVERY 17
INTEGRIN A SUBUNITS 21
INTEGRIN * SUBUNITS 36
GENERAL FUNCTIONAL PROPERTIES OF INTEGRINS 41
3. LEUKOCYTE-SPECIFIC INTEGRINS: THE P*2 INTEGRIN SUBFAMILY 47
HISTORICAL BACKGROUND 47
LEUKOCYTE INTEGRIN EXPRESSION 61
LEUKOCYTE INTEGRIN CONSTITUTIVE EXPRESSION IN NORMAL AND CLINICAL
CONDITIONS 63
DEVELOPMENTALLY-REGULATED EXPRESSION OF ABA/$2 AND AX/P2 68 MOLECULAR
BASIS FOR THE CONSTITUTIVE AND REGULATED EXPRESSION OF THE LEUKOCYTE
INTEGRINS 69
COMMON REGULATORY ELEMENTS 72
SPECIFIC STRUCTURES 74
4. ADHESIVE FUNCTIONS OF THE LEUKOCYTE INTEGRINS AND THEIR LIGANDS 79
INTRODUCTION 79
FUNCTIONAL ACTIVITY OF EACH LEUKOCYTE INTEGRIN 80
IDENTIFICATION OF LIGAND-BINDING RESIDUES 94
5. LEUKOCYTE ADHESION DEFICIENCY 99
INTRODUCTION 99
OTHER SITUATIONS WITH ALTERED LEUKOCYTE INTEGRIN EXPRESSION OR FUNCTION
109
IMAGE 2
6. SIGNALING FUNCTIONS OF THE LEUKOCYTE INTEGRINS: LEUKOCYTE
INTEGRINS AS TWO-WAY SIGNAL TRANSDUCTION DEVICES 119 OUTSIDE-IN
SIGNALING 119
INSIDE-OUT SIGNALING 124
ACTIVATING LIGANDS 128
INTRACELLULAR EVENTS 132
A ROLE FOR CYTOSKELETON 134
7. SYNOPSIS AND FUTURE DIRECTIONS 139
FUTURE DIRECTIONS 142
REFERENCES 145
INDEX ....207
|
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| bvnumber | BV011091867 |
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| discipline | Biologie |
| format | Book |
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| id | DE-604.BV011091867 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:03:51Z |
| institution | BVB |
| isbn | 3540613536 |
| language | German |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-007430648 |
| oclc_num | 75834191 |
| open_access_boolean | |
| physical | 208 S. Ill., graph. Darst. |
| publishDate | 1996 |
| publishDateSearch | 1996 |
| publishDateSort | 1996 |
| publisher | Springer Landes |
| record_format | marc |
| series2 | Molecular biology intelligence unit |
| spelling | Corbí, Angel L. Verfasser aut Leukocyte integrins structure, expression and function Angel L. Corbí New York [u.a.] Springer 1996 Austin Landes 208 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Molecular biology intelligence unit Literaturverz. S. 145 - 206 Leukozyt (DE-588)4074195-3 gnd rswk-swf Integrine (DE-588)4278201-6 gnd rswk-swf Leukozyt (DE-588)4074195-3 s Integrine (DE-588)4278201-6 s DE-604 SWB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007430648&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Corbí, Angel L. Leukocyte integrins structure, expression and function Leukozyt (DE-588)4074195-3 gnd Integrine (DE-588)4278201-6 gnd |
| subject_GND | (DE-588)4074195-3 (DE-588)4278201-6 |
| title | Leukocyte integrins structure, expression and function |
| title_auth | Leukocyte integrins structure, expression and function |
| title_exact_search | Leukocyte integrins structure, expression and function |
| title_full | Leukocyte integrins structure, expression and function Angel L. Corbí |
| title_fullStr | Leukocyte integrins structure, expression and function Angel L. Corbí |
| title_full_unstemmed | Leukocyte integrins structure, expression and function Angel L. Corbí |
| title_short | Leukocyte integrins |
| title_sort | leukocyte integrins structure expression and function |
| title_sub | structure, expression and function |
| topic | Leukozyt (DE-588)4074195-3 gnd Integrine (DE-588)4278201-6 gnd |
| topic_facet | Leukozyt Integrine |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007430648&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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