Multiple sequence alignment by parallel simulated annealing:

Abstract: "We have applied simulated annealing algorithms to solve problems of multiple alignment. A temperature parallel algorithm, a simple parallel algorithm and a sequential algorithm were tested on a problem. The results were compared with the result obtained by the conventional tree-based...

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Bibliographic Details
Format: Book
Language:English
Published: Tokyo, Japan 1992
Series:Shin-Sedai-Konpyūta-Gijutsu-Kaihatsu-Kikō <Tōkyō>: ICOT technical report 730
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Summary:Abstract: "We have applied simulated annealing algorithms to solve problems of multiple alignment. A temperature parallel algorithm, a simple parallel algorithm and a sequential algorithm were tested on a problem. The results were compared with the result obtained by the conventional tree-based method. As a result, every annealing algorithm has produced a better energy than the tree-based method. Particularly, either of the parallel annealing algorithm has reached the best energy, probably the optimal solution. We consider the temperature parallel algorithm of simulated annealing to be the most suitable for finding the optimal multiple alignment, because the algorithm does not require any re- scheduling for further optimization
The algorithm is also suitable for refinement of a multiple alignment obtained by other heuristic methods.
Physical Description:12 S.

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