Estrogen and breast cancer:
Saved in:
| Main Author: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
New York [u.a.]
Springer [u.a.]
1996
|
| Series: | Medical intelligence unit
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | 207 S. Ill., graph. Darst. |
| ISBN: | 3540607773 0412103710 |
Staff View
MARC
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| 100 | 1 | |a Miller, W. R. |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Estrogen and breast cancer |c W. R. Miller |
| 264 | 1 | |a New York [u.a.] |b Springer [u.a.] |c 1996 | |
| 300 | |a 207 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Medical intelligence unit | |
| 650 | 4 | |a DOJKA - fiziologija | |
| 650 | 4 | |a DOJKA, NOVOTVORBE - etiologija - patologija | |
| 650 | 4 | |a ESTROGENI | |
| 650 | 4 | |a BREAST NEOPLASMS |x etiology |x pathology | |
| 650 | 4 | |a BREAST |x physiology | |
| 650 | 4 | |a ESTROGENS | |
| 650 | 0 | 7 | |a Brustkrebs |0 (DE-588)4008528-4 |2 gnd |9 rswk-swf |
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| 856 | 4 | 2 | |m DNB Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007156990&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-007156990 | |
Record in the Search Index
| _version_ | 1808227852645040128 |
|---|---|
| adam_text |
CONTENTS
1.
INTRODUCTION
.
1
ESTROGENS
.
1
BREAST
CANCER
.
12
2.
ESTROGENS
AND
THE
NORMAL
BREAST
.
25
ESTROGENS
AND
BREAST
DEVELOPMENT
AT
PUBERTY
.25
THE
MATURE
RESTING
BREAST
.
27
ESTROGEN
AND
BREAST
INVOLUTION
AT
MENOPAUSE
.
29
SUMMARY
.
32
3.
ESTROGENS
AND
THE
RISK
OF
BREAST
CANCER
.
35
EPIDEMIOLOGICAL
EVIDENCE
.35
CLINICO-PATHOLOGICAL
EVIDENCE
.
43
ENDOCRINOLOGICAL
EVIDENCE
.
44
METABOLIC
EVIDENCE
.
50
MOLECULAR
EVIDENCE
.
51
ESTROGENS
AS
INITIATORS
.
52
ESTROGENS
AS
CO-INITIATORS/PROMOTERS
.
52
CONCLUSIONS
.
53
4.
ESTROGEN
AND
TUMOR
BEHAVIOR
.
63
EPIDEMIOLOGICAL
EVIDENCE
.
63
CLINICO-PATHOLOGICAL
EVIDENCE
.
65
ENDOCRINOLOGICAL
EVIDENCE
.
66
METABOLIC
DATA
.
68
MOLECULAR
EVIDENCE
.
68
CONCLUSIONS
.
69
5.
SOURCES
OF
ESTROGEN
AND
SITES
OF
BIOSYNTHESIS
.
75
EXOGENOUS
SOURCES
OF
ESTROGENS
.
76
GLANDULAR
SYNTHESIS
OF
ESTROGEN
.
78
ADRENAL
CORTEX
.
81
EXTRAGLANDULAR
SYNTHESIS
.
81
SUMMARY
.
88
6.
LEVELS
AND
PATTERNS
OF
ESTROGEN
WITHIN
THE
BREAST,
ITS
FLUIDS
AND
TISSUES
.
95
INTRODUCTION
.
95
MILK
.
95
NIPPLE
ASPIRATES
.
96
BREAST
CYST
FLUIDS
.
98
BREAST
TISSUES
.
102
GENERAL
FINDINGS
.
102
SPECIFIC
DETAILS
.
103
MECHANISM
OF
ACCUMULATION
.
106
SUMMARY
.
107
7.
MECHANISM
OF
ESTROGEN
ACTION
.
ILL
ESTROGEN
RECEPTORS
.
ILL
NUCLEIC
ACID
SYNTHESIS
.
113
SECRETION
OF
POLYPEPTIDE
GROWTH
FACTORS
.
113
PRODUCTION
OF
PROTEOLYTIC
ENZYMES
.
116
ONCOGENES
.
117
SUMMARY
.
118
8.
ESTROGENS
AND
ENDOCRINE
THERAPY
FOR
BREAST
CANCER
.
125
HISTORICAL
BACKGROUND
.
125
OVARIAN
ABLATION
.
126
ADRENAL
AND
PITUITARY
ABLATION
.
127
LHRH
AGONIST
ANALOGUES
.
128
ADDITIVE
THERAPY
WITH
ESTROGENS
.
132
ANTIESTROGENS
.
132
AROMATASE
INHIBITORS
.
137
NOVEL
METHODS
OF
ESTROGEN
DEPRIVATION
.
142
FUTURE
PERSPECTIVES
.
143
9.
PREDICTION
OF
ESTROGEN
SENSITIVITY/DEPENDENCE
.
151
ESTROGEN
RECEPTORS
.
151
RELATIONSHIP
BETWEEN
ESTROGEN
RECEPTORS
AND
RESPONSE
TO
ENDOCRINE
THERAPY
FOR
ADVANCED
BREAST
CANCER
.
153
ESTROGEN
RECEPTORS
AND
PROGNOSIS
IN
PATIENTS
WITH
EARLY
BREAST
CANCER
.
155
PROGESTERONE
RECEPTORS
.
158
PS2
.
160
ESTROGEN
INDUCIBLE
GENES
.
160
HSP27
(HEAT
SHOCK
PROTEIN
27,000)
.
161
TYPE
I
TYROSINE
KINASE
RECEPTORS
.
162
SUMMARY
.
162
10.
ESTROGEN
INDEPENDENCE
.
171
PRIMARY
RESISTANCE
.
171
ACQUIRED
RESISTANCE
.
171
RESISTANCE
ASSOCIATED
WITH
INDIVIDUAL
TYPES
OF
ESTROGEN
DEPRIVATION
.
179
ASSOCIATION
WITH
OTHER
FEATURES
OF
AGGRESSIVE
BEHAVIOR
.
186
SUMMARY
.
187
11.
FUTURE
PERSPECTIVES
.
197
ESTROGEN
AND
THE
NORMAL
BREAST
.
198
ESTROGENS
AND
RISK
OF
BREAST
CANCER
.
198
ESTROGENS
AND
TUMOR
BEHAVIOR
.
199
SOURCES
OF
ESTROGEN
.
199
LEVELS
AND
PATTERNS
OF
ESTROGEN
IN
THE
BREAST
.
200
MECHANISM
OF
ESTROGEN
ACTION
.
200
ESTROGEN
DEPRIVATION
THERAPY
.
200
PREDICTION
OF
ESTROGEN
SENSITIVITY/DEPENDENCIES
.
201
RESISTANCE
TO
ENDOCRINE
THERAPY
.
201
SUMMARY
.
202
INDEX
.
205 |
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| id | DE-604.BV010718418 |
| illustrated | Illustrated |
| indexdate | 2024-08-24T00:47:40Z |
| institution | BVB |
| isbn | 3540607773 0412103710 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-007156990 |
| oclc_num | 439278716 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-29 |
| owner_facet | DE-355 DE-BY-UBR DE-29 |
| physical | 207 S. Ill., graph. Darst. |
| publishDate | 1996 |
| publishDateSearch | 1996 |
| publishDateSort | 1996 |
| publisher | Springer [u.a.] |
| record_format | marc |
| series2 | Medical intelligence unit |
| spelling | Miller, W. R. Verfasser aut Estrogen and breast cancer W. R. Miller New York [u.a.] Springer [u.a.] 1996 207 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Medical intelligence unit DOJKA - fiziologija DOJKA, NOVOTVORBE - etiologija - patologija ESTROGENI BREAST NEOPLASMS etiology pathology BREAST physiology ESTROGENS Brustkrebs (DE-588)4008528-4 gnd rswk-swf Östrogene (DE-588)4075616-6 gnd rswk-swf Brustkrebs (DE-588)4008528-4 s Östrogene (DE-588)4075616-6 s DE-604 DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007156990&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Miller, W. R. Estrogen and breast cancer DOJKA - fiziologija DOJKA, NOVOTVORBE - etiologija - patologija ESTROGENI BREAST NEOPLASMS etiology pathology BREAST physiology ESTROGENS Brustkrebs (DE-588)4008528-4 gnd Östrogene (DE-588)4075616-6 gnd |
| subject_GND | (DE-588)4008528-4 (DE-588)4075616-6 |
| title | Estrogen and breast cancer |
| title_auth | Estrogen and breast cancer |
| title_exact_search | Estrogen and breast cancer |
| title_full | Estrogen and breast cancer W. R. Miller |
| title_fullStr | Estrogen and breast cancer W. R. Miller |
| title_full_unstemmed | Estrogen and breast cancer W. R. Miller |
| title_short | Estrogen and breast cancer |
| title_sort | estrogen and breast cancer |
| topic | DOJKA - fiziologija DOJKA, NOVOTVORBE - etiologija - patologija ESTROGENI BREAST NEOPLASMS etiology pathology BREAST physiology ESTROGENS Brustkrebs (DE-588)4008528-4 gnd Östrogene (DE-588)4075616-6 gnd |
| topic_facet | DOJKA - fiziologija DOJKA, NOVOTVORBE - etiologija - patologija ESTROGENI BREAST NEOPLASMS etiology pathology BREAST physiology ESTROGENS Brustkrebs Östrogene |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007156990&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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