Stability of insulin: studies on the physical and chemical stability of insulin in pharmaceutical formulation
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Boston u.a.
Kluwer Acad. Publ.
1994
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 128 S. Ill., graph. Darst. |
| ISBN: | 0792389778 |
Internformat
MARC
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Datensatz im Suchindex
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| adam_text | C STABILITY OF INSULIN STUDIES ON THE PHYSICAL AND CHEMICAL STABILITY OF
INSULIN IN PHARMACEUTICAL FORMULATION JENS BRANGE NOVO RESEARCH
INSTITUTE NOVO ALLE DK-2880 BAGSVAERD DENMARK KLUWER ACADEMIC PUBLISHERS
BOSTON / DORDRECHT / LONDON CONTENTS INTRODUCTION 1. HISTORICAL
PERSPECTIVE A. INTRODUCTION B. EARLY OBSERVATIONS RELATING TO STABILITY
C. INSULIN PURITY II. SCENARIO: STRUCTURE OF THE INSULIN MOLECULE A.
PRIMARY STRUCTURE B. SECONDARY AND TERTIARY STRUCTURE C. QUATERNARY
STRUCTURE (SELF-ASSOCIATION) D. STRUCTURE OF INSULIN IN PHARMACEUTICAL
FORMULATIONS III. STUDIES ON INSULIN STABILITY A. INTRODUCTION B.
BIOLOGICAL STABILITY C. PHYSICAL STABILITY 1. INTRODUCTION 2. INSULIN
FIBRILLATION A. FORMATION AND PROPERTIES OF INSULIN FIBRILS B. STRUCTURE
OF FIBROUS INSULIN C. PREVENTION OF INSULIN FIBRILLATION D. FIBRIL
FORMATION IN VIVO D. CHEMICAL STABILITY 1. INTRODUCTION 2. FORMATION OF
HYDROLYSIS PRODUCTS A. DEAMIDATION REACTIONS B. CHAIN CLEAVAGE 3. DI-
AND POLYMERIZATION A. AMINE REACTIONS B. DISULFIDE INTERCHANGE REACTIONS
4. INFLUENCE OF PH AND AUXILIARY SUBSTANCES 5. EFFECT OF TEMPERATURE 6.
KINETICS AND MECHANISMS 7. PROPERTIES OF TRANSFORMATION PRODUCTS 8.
INFLUENCE ON THE QUALITY OF PHARMACEUTICAL PREPARATIONS E.
STRUCTURE-STABILITY RELATIONSHIP SUMMARY AND CONCLUSION RESUME OG
KONKLUSION REFERENCES REDRODUCTIONS OF SUBMITTED DAOERS 6 7 7 7 G * 1
1 11 12 12 15 17 17 17 18 18 18 18 19 21 22 23 23 23 24 26 28 28 30 30
30 32 35 36 37 37 42 46 60
|
| any_adam_object | 1 |
| author | Brange, Jens |
| author_facet | Brange, Jens |
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| bvnumber | BV010559573 |
| callnumber-first | R - Medicine |
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| callnumber-raw | RS431.I56 |
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| callnumber-sort | RS 3431 I56 |
| callnumber-subject | RS - Pharmacy |
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| dewey-full | 615.3/65 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615.3/65 |
| dewey-search | 615.3/65 |
| dewey-sort | 3615.3 265 |
| dewey-tens | 610 - Medicine and health |
| discipline | Chemie / Pharmazie Medizin |
| format | Book |
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| id | DE-604.BV010559573 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T17:55:04Z |
| institution | BVB |
| isbn | 0792389778 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-007039908 |
| oclc_num | 32133401 |
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| owner | DE-355 DE-BY-UBR |
| owner_facet | DE-355 DE-BY-UBR |
| physical | 128 S. Ill., graph. Darst. |
| publishDate | 1994 |
| publishDateSearch | 1994 |
| publishDateSort | 1994 |
| publisher | Kluwer Acad. Publ. |
| record_format | marc |
| spelling | Brange, Jens Verfasser aut Stability of insulin studies on the physical and chemical stability of insulin in pharmaceutical formulation Jens Brange Boston u.a. Kluwer Acad. Publ. 1994 128 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Drug stability Insulin Stability Insulin chemistry Insulin physiology Arzneimittelstabilität (DE-588)4122835-2 gnd rswk-swf Insulin (DE-588)4027221-7 gnd rswk-swf Insulin (DE-588)4027221-7 s Arzneimittelstabilität (DE-588)4122835-2 s DE-604 GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007039908&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Brange, Jens Stability of insulin studies on the physical and chemical stability of insulin in pharmaceutical formulation Drug stability Insulin Stability Insulin chemistry Insulin physiology Arzneimittelstabilität (DE-588)4122835-2 gnd Insulin (DE-588)4027221-7 gnd |
| subject_GND | (DE-588)4122835-2 (DE-588)4027221-7 |
| title | Stability of insulin studies on the physical and chemical stability of insulin in pharmaceutical formulation |
| title_auth | Stability of insulin studies on the physical and chemical stability of insulin in pharmaceutical formulation |
| title_exact_search | Stability of insulin studies on the physical and chemical stability of insulin in pharmaceutical formulation |
| title_full | Stability of insulin studies on the physical and chemical stability of insulin in pharmaceutical formulation Jens Brange |
| title_fullStr | Stability of insulin studies on the physical and chemical stability of insulin in pharmaceutical formulation Jens Brange |
| title_full_unstemmed | Stability of insulin studies on the physical and chemical stability of insulin in pharmaceutical formulation Jens Brange |
| title_short | Stability of insulin |
| title_sort | stability of insulin studies on the physical and chemical stability of insulin in pharmaceutical formulation |
| title_sub | studies on the physical and chemical stability of insulin in pharmaceutical formulation |
| topic | Drug stability Insulin Stability Insulin chemistry Insulin physiology Arzneimittelstabilität (DE-588)4122835-2 gnd Insulin (DE-588)4027221-7 gnd |
| topic_facet | Drug stability Insulin Stability Insulin chemistry Insulin physiology Arzneimittelstabilität Insulin |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007039908&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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