Marrow and stem cell processing for transplantation:
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Bethesda, Md.
American Assoc. of Blood Banks
1995
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | X, 225 S. Ill., graph. Darst. |
| ISBN: | 1563950421 |
Staff View
MARC
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| 245 | 1 | 0 | |a Marrow and stem cell processing for transplantation |c ed. Larry C. Lasky ... |
| 264 | 1 | |a Bethesda, Md. |b American Assoc. of Blood Banks |c 1995 | |
| 300 | |a X, 225 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
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| 650 | 4 | |a Bone Marrow Cells |v Congresses | |
| 650 | 4 | |a Bone Marrow Transplantation |v Congresses | |
| 650 | 4 | |a Bone marrow |x Transplantation |v Congresses | |
| 650 | 4 | |a Hematopoietic stem cells |x Transplantation |v Congresses | |
| 650 | 4 | |a Stem Cell Transplantation |v Congresses | |
| 650 | 4 | |a Stem Cells |x cytology |v Congresses | |
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Record in the Search Index
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|---|---|
| adam_text | Contents
Foreword ix
1. Clinical Background for Marrow and Progenitor Cell
Processing 1
Phyllis I. Warkentin, MD
Rationale for Hematopoietic Stem Cell Transplantation 2
Types of Transplants 2
Bone Marrow Collection 4
Processing of Allogeneic Bone Marrow 5
Processing of Autologous Bone Marrow 12
Summary 15
References 15
2. Progenitor Assays, How Much and When? 21
Gary Spitzer, MD; Sulabha S. Kulkarni, PhD; Nancy Kron
mueller, MS; and Douglas R. Adkins, MD
Assays in Semi Solid Media 23
Liquid Culture Assays 24
Application of Culture Systems 25
The Progenitor Cell Content of the Marrow Graft Predicts
Engraftment Kinetics 25
How Much Is Enough for Autologous Bone Marrow
Transplantation? 26
How Much Is Enough for Peripheral Blood Stem Cells? 28
Do CD34 Positive Cells Predict the CFU GM Content of
Peripheral Blood Stem Cells Adequately? 30
Conclusions 32
References 33
3. Bacterial and Fungal Contamination of Stem Cell
Components 35
Janice M. Davis, MAS, MT(ASCP)SBB
Bacterial Contamination 36
Fungal Contamination 41
Equipment as a Source of Contamination 41
Practical Considerations 42
Guidelines for the Infusion of Culture Positive
Components 43
Documentation 44
Summary 45
References 46
4. Routine Methods for Preparing Hematopoietic Progenitor
Cell Components 51
Charles S. Carter, BS; Ronald Gress, MD; and Harvey G.
Klein, MD
Plasma and Fatty Substance Elimination 54
Sedimentation Techniques at Low g Forces 56
Buffy Coat Preparation and Mononuclear Cell
Enrichment 57
Isopycnic Separation Techniques 61
Summary 63
References 64
5. Cryopreservation of Hematopoietic Stem Cells 69
Patrick J. Stiff, MD
Cryopreservation Basics 69
Cryoprotective Agents 71
Cryopreservation Techniques 73
Current Controversies in Stem Cell Cryopreservation 75
Conclusion 78
References 79
6. Malignant Cell Purging: Immunophysical Techniques 83
Adrian P. Gee, PhD
Tumor Purging Techniques 84
Physical Methods of Purging 85
Immunophysical Purging 87
Immunomagnetic Separation 91
Clinical Efficacy of Purging 97
Future Studies 99
References 100
7. Malignant Cell Purging: Monoclonal Antibodies 103
Kenneth C. Anderson, MD
In Vivo Use of Monoclonal Antibodies 103
In Vitro Use of MoAbs 106
Future Directions 115
References 116
8. Pharmacologic Purging of Bone Marrow 123
Scott D. Rowley, MD, FACP
Rationale for Purging 124
Preclinical Evaluation of Pharmacologic Purging Agents.. 127
Purging With Activated Oxazaphosphorines 129
Purging With Other Pharmacologies 136
Summary 140
References 140
9. T Cell Depletion of Allogeneic Bone Marrow Transplants
by Immunologic and Physical Techniques 149
Nancy H. Collins, PhD; Adrian P. Gee, PhD; and P. Jean
Henslee Downey, MD
Histocompatibility 150
Graft vs Host Disease 150
The Paradox of T Cell Depletion in Allogeneic
Transplantation 152
Evaluation of T Cell Depleted Bone Marrow 153
T Cell Depletion Methods 158
Defining Adequate Levels of T Cell Depletion 164
The T Cell Depletion Balance Sheet 164
References 165
10. Peripheral Blood Stem Cells 169
Larry C. Lasky, MD
History 169
Mobilization 170
Collection Techniques 171
PBSC Processing 174
Clinical Applications 176
Summary 180
References 181
11. Human Umbilical Cord and Placental Blood
Transplantation 191
Hal E. Broxmeyer, PhD
Clinical Transplantation of Cord Blood Cells 192
Cord Blood Transplantation in Adults 194
In Vitro Expansion of Progenitor Cells 195
Cord Blood Banks 195
References 197
12. Ex Vivo Expansion of CD34+ Progenitor Cells 201
5. Heimfeld, PhD; R. Fei, MD; Z.Tsui; B. Fogarty;
P. Thompson; R. J. Berenson, MD
Use of Growth Factor Dependent Culture Systems 203
Ex Vivo Expansion of Progenitor Cells 204
A New System 204
Summary 205
References 206
13. Isolation of Human Hematopoietic Stem Cells 209
Irwin D. Bernstein, MD; Robert G. Andrews MD; and Scott
Rowley, MD
Evidence That the CD34+ Hematopoietic Precursors
Contain the Pluripotent Hematopoietic Stem Cell 211
In Vitro Correlates and Conditions for Propagating
CD34+Cell Subsets 214
Summary 216
References 216
Index 221
|
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| genre | (DE-588)1071861417 Konferenzschrift 1993 Tampa Fla. gnd-content |
| genre_facet | Konferenzschrift 1993 Tampa Fla. |
| id | DE-604.BV010531119 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T17:54:35Z |
| institution | BVB |
| isbn | 1563950421 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-007019863 |
| oclc_num | 31814833 |
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| physical | X, 225 S. Ill., graph. Darst. |
| publishDate | 1995 |
| publishDateSearch | 1995 |
| publishDateSort | 1995 |
| publisher | American Assoc. of Blood Banks |
| record_format | marc |
| spelling | Marrow and stem cell processing for transplantation ed. Larry C. Lasky ... Bethesda, Md. American Assoc. of Blood Banks 1995 X, 225 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Bone Marrow Cells Congresses Bone Marrow Transplantation Congresses Bone marrow Transplantation Congresses Hematopoietic stem cells Transplantation Congresses Stem Cell Transplantation Congresses Stem Cells cytology Congresses Transplantat (DE-588)4185918-2 gnd rswk-swf Knochenmarktransplantation (DE-588)4164288-0 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1993 Tampa Fla. gnd-content Knochenmarktransplantation (DE-588)4164288-0 s Transplantat (DE-588)4185918-2 s DE-604 Lasky, Larry C. Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007019863&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Marrow and stem cell processing for transplantation Bone Marrow Cells Congresses Bone Marrow Transplantation Congresses Bone marrow Transplantation Congresses Hematopoietic stem cells Transplantation Congresses Stem Cell Transplantation Congresses Stem Cells cytology Congresses Transplantat (DE-588)4185918-2 gnd Knochenmarktransplantation (DE-588)4164288-0 gnd |
| subject_GND | (DE-588)4185918-2 (DE-588)4164288-0 (DE-588)1071861417 |
| title | Marrow and stem cell processing for transplantation |
| title_auth | Marrow and stem cell processing for transplantation |
| title_exact_search | Marrow and stem cell processing for transplantation |
| title_full | Marrow and stem cell processing for transplantation ed. Larry C. Lasky ... |
| title_fullStr | Marrow and stem cell processing for transplantation ed. Larry C. Lasky ... |
| title_full_unstemmed | Marrow and stem cell processing for transplantation ed. Larry C. Lasky ... |
| title_short | Marrow and stem cell processing for transplantation |
| title_sort | marrow and stem cell processing for transplantation |
| topic | Bone Marrow Cells Congresses Bone Marrow Transplantation Congresses Bone marrow Transplantation Congresses Hematopoietic stem cells Transplantation Congresses Stem Cell Transplantation Congresses Stem Cells cytology Congresses Transplantat (DE-588)4185918-2 gnd Knochenmarktransplantation (DE-588)4164288-0 gnd |
| topic_facet | Bone Marrow Cells Congresses Bone Marrow Transplantation Congresses Bone marrow Transplantation Congresses Hematopoietic stem cells Transplantation Congresses Stem Cell Transplantation Congresses Stem Cells cytology Congresses Transplantat Knochenmarktransplantation Konferenzschrift 1993 Tampa Fla. |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=007019863&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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