The unique hepatitis delta virus:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | Undetermined |
| Veröffentlicht: |
New York u.a.
Springer u.a.
1995
|
| Schriftenreihe: | Medical intelligence unit
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIII, 143 S. Ill., graph. Darst. |
| ISBN: | 157059144X 3540589058 |
Internformat
MARC
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| 020 | |a 157059144X |9 1-57059-144-X | ||
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| 245 | 1 | 0 | |a The unique hepatitis delta virus |c Gail Dinter-Gottlieb |
| 264 | 1 | |a New York u.a. |b Springer u.a. |c 1995 | |
| 300 | |a XIII, 143 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Medical intelligence unit | |
| 650 | 0 | 7 | |a Hepatitis-D-Virus |0 (DE-588)4264860-9 |2 gnd |9 rswk-swf |
| 655 | 7 | |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
| 689 | 0 | 0 | |a Hepatitis-D-Virus |0 (DE-588)4264860-9 |D s |
| 689 | 0 | |5 DE-604 | |
| 700 | 1 | |a Dinter-Gottlieb, Gail |e Sonstige |4 oth | |
| 856 | 4 | 2 | |m DNB Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=006783898&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-006783898 | |
Datensatz im Suchindex
| _version_ | 1808228099011117056 |
|---|---|
| adam_text |
-
CONTENTS
==^=
CONTRIBUTORS
.
XI.
INTRODUCTION
.XIII.
1.
A
PLANT
MOLECULAR
VIROLOGIST
'
S
VIEW
OF
AN
INTRIGUING
VIRUS
AND
ITS
CATALYTIC
RNA
.
1
ROBERT
H.
SYMONS
INTRODUCTION
.
1
COMPARISON
OF
HDV
RNA
WITH
VIROIDS
AND
THE
SELF-CLEAVING
PLANT
SATELLITE
RNAS
.
3
SECONDARY
STRUCTURE
MODELS
FOR
THE
SELF-CLEAVAGE
SITES
OF
GENOMIC
AND
ANTI-GENOMIC
HDV-COMPETING
STRUCTURES
GENERATE
MUCH
DISCUSSION
.
5
CONCLUDING
COMMENTS
.
9
2.
THE
CATALYTIC
RNAS
FROM
HEPATITIS
DELTA
VIRUS:
STRUCTURE,
FUNCTION
AND
APPLICATIONS
.
11
N.
KYLE
TANNER
SELF-CLEAVAGE
SITES
.
12
MINIMAL
SEQUENCE
LENGTH
.
12
REACTION
CONDITIONS
.
14
RNA
SECONDARY
STRUCTURE
MODELS
.
14
SEQUENCE
COMPARISONS
.
14
MUTATIONAL
DATA
.
19
NUCLEASE
CHEMICAL
AND
PROBING
DATA
.
23
CLEAVAGE
OF
SUBSTRATE
RNAS
ADDED
IN
TRANS
.
23
POSSIBLE
ROLES
OF
THE
SELF-CLEAVAGE
REACTION
IN
VIVO
.
25
CONCLUSIONS
AND
FUTURE
DIRECTIONS
.
26
3.
DESIGNING
A
RIBOZYME
FROM
THE
HEPATITIS
DELTA
VIRUS
.
33
GAIL
DINTER-GOTTLIEB
INTRODUCTION
.
33
REDUCING
THE
RNA
IN
SIZE
AS
A
FIRST
STEP
.
34
THE
NATURE
OF
THE
RIBOZYME
TARGET
.
34
STRUCTURAL
COMPENSATION
IN
A
SELF-CLEAVING
RNA
.
35
STRUCTURAL
COMPENSATION
MIGHT
ALLOW
FOR
A
NEW
RIBOZYME
TARGET
.
36
THE
HEPATITIS
DELTA
ANTIGENOMIC
RNAS
ARE
HIGHLY
STABLE
IN
FORMAMIDE
.
36
THE
STABILITY
IN
FORMAMIDE
MAY
BE
REFLECTED
UNDER
PHYSIOLOGICAL
CONDITIONS
.
38
THE
PLASTICITY
OF
THE
DELTA
RNA
.
39
SUBSTITUTION
OF
ADENOSINE
RESIDUES
BY
7-DEAZA-ADENOSINE
AS
A
PROBE
FOR
TERTIARY
INTERACTIONS
.
39
CLEAVAGE
RATES
MAY
VARY
IN
VITRO
.
40
THE
PITFALLS
OF
DELETION
MUTAGENESIS
.
41
SITE
SPECIFIC
MUTAGENESIS
AT
THE
CLEAVAGE
SITE
OF
THE
GENOMIC
RNA
.
42
TARGETING
A
SUBSTRATE
WITH
THE
DELTA
RIBOZYME
.
44
"
LEARNING
FROM
THE
RNA
"
.
44
4.
HDV
AS
A
PRECEDENT
FOR
RNA-DIRECTED
RNA
SYNTHESIS
BY
RNA
POLYMERASE
II
.
47
JOHNM.
TAYLOR
5.
CORRELATION
OF
STRUCTURE
AND
BIOLOGICAL
FUNCTION
IN
THE
RNA
OF
THE
DELTA
HEPATITIS
AGENT
.55
HUGH
D.
ROBERTSON,
OLIVIA
D.
NEEL,
DAVID
A.
CIRCLE,
MICHAEL
B.
MATHEWS
INTRODUCTION
.
55
DIFFERENTIAL
REGULATION
OF
DELTA
RIBOZYME
ACTION
.
56
DELTA
GENOMIC
RNA
ACTIVATES
A
CELLULAR
PROTEIN
KINASE
.
60
CONCLUSIONS
.
66
6.
HEPATITIS
DELTA
ANTIGEN
.
69
THOMAS
B.
MACNAUGHTON,
ERIC
J.
GOWANS
INTRODUCTION
.
69
SPECIES
AND
LOCALIZATION
OF
HDAG
.
69
THE
HEPATITIS
DELTA
VIRION
.
70
ORIGIN
OF
THE
TWO
HDAG
SPECIES
.
70
TRANS-ACTIVATION
AND
TRANS-INHIBITION
.
71
INTERFERENCE
AND
CYTOTOXICITY
.
72
FUNCTIONAL
DOMAINS
OF
HDAG
.
72
HDV
MORPHOGENESIS
.
76
HDAG
AND
HDV
REPLICATION
.
76
CONCLUSION
.
79
7.
PRENYLATION
AND
VIRION
MORPHOGENESIS
.
83
JEFFREY
S.
GLENN
INTRODUCTION
.83
HDV
PARTICLE
COMPOSITION
.
83
FORMATION
OF
VIRUS
PARTICLES
.
84
PRENYLATION
AND
ITS
ROLE
IN
VIRUS
ASSEMBLY
.
85
THERAPEUTIC
STRATEGIES
.
87
FUTURE
DIRECTIONS
.
88
CONCLUSION
.
89
8.
STUDIES
OF
FUNCTIONAL
ROLES
OF
HEPATITIS
DELTA
ANTIGEN
IN
DELTA
VIRUS
RNA
REPLICATION
.95
SOON
B.
HWANG,
KING-SONG
JENG,
MICHAEL
M.
C.
LAI
MATERIALS
AND
METHODS
.
96
RESULTS
AND
DISCUSSION
.
97
CONCLUSIONS
.
106
9.
HEPATITIS
DELTA
VIRUS:
RNA
EDITING
AND
GENOTYPE
VARIATIONS
.
ILL
JOHN
L.
CASEY,
JOHN
L.
GERIN
INTRODUCTION
.
ILL
THE
ROLE
OF
RNAEDITING
IN
HDV
REPLICATION
.
ILL
DETECTION
OF
EDITING
.
113
ANALYSIS
OF
EDITING
IN
TRANSFECTED
CELLS
IN
CULTURE
.
114
NEW
APPROACHES
TO
THE
ANALYSIS
OF
HDV
RNA
EDITING
.
116
ANALYSIS
OF
HDV
GENOTYPES:
INSIGHTS
GAINED
AND
QUESTIONS
RAISED
.
120
FUTURE
DIRECTIONS
.
121
10.
HEPATITIS
DELTA
VIRUS
INFECTION:
MEDICAL
ASPECTS
.
125
MARIO
RIZZETTO,
ANTONIO
PONZETTO
MECHANISMS
OF
HEPATITIS
DELTA
VIRUS
INFECTION
.
125
PATHOGENESIS
.
126
DIAGNOSIS
.
127
MEDICAL
ASPECTS
.
129
VACCINATION
.
132
THERAPY
.
132
TRANSPLANTATION
.
134
INDEX
.
141 |
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| ctrlnum | (OCoLC)845009522 (DE-599)BVBBV010209091 |
| dewey-full | 616.3623 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.3623 |
| dewey-search | 616.3623 |
| dewey-sort | 3616.3623 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Book |
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| genre_facet | Aufsatzsammlung |
| id | DE-604.BV010209091 |
| illustrated | Illustrated |
| indexdate | 2024-08-24T00:51:34Z |
| institution | BVB |
| isbn | 157059144X 3540589058 |
| language | Undetermined |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-006783898 |
| oclc_num | 845009522 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-29 DE-578 |
| owner_facet | DE-355 DE-BY-UBR DE-29 DE-578 |
| physical | XIII, 143 S. Ill., graph. Darst. |
| publishDate | 1995 |
| publishDateSearch | 1995 |
| publishDateSort | 1995 |
| publisher | Springer u.a. |
| record_format | marc |
| series2 | Medical intelligence unit |
| spelling | The unique hepatitis delta virus Gail Dinter-Gottlieb New York u.a. Springer u.a. 1995 XIII, 143 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Medical intelligence unit Hepatitis-D-Virus (DE-588)4264860-9 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Hepatitis-D-Virus (DE-588)4264860-9 s DE-604 Dinter-Gottlieb, Gail Sonstige oth DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=006783898&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | The unique hepatitis delta virus Hepatitis-D-Virus (DE-588)4264860-9 gnd |
| subject_GND | (DE-588)4264860-9 (DE-588)4143413-4 |
| title | The unique hepatitis delta virus |
| title_auth | The unique hepatitis delta virus |
| title_exact_search | The unique hepatitis delta virus |
| title_full | The unique hepatitis delta virus Gail Dinter-Gottlieb |
| title_fullStr | The unique hepatitis delta virus Gail Dinter-Gottlieb |
| title_full_unstemmed | The unique hepatitis delta virus Gail Dinter-Gottlieb |
| title_short | The unique hepatitis delta virus |
| title_sort | the unique hepatitis delta virus |
| topic | Hepatitis-D-Virus (DE-588)4264860-9 gnd |
| topic_facet | Hepatitis-D-Virus Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=006783898&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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