Drug stereochemistry: analytical methods and pharmacology
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York, NY u.a.
Dekker
1993
|
| Ausgabe: | 2. ed., rev. and expanded |
| Schriftenreihe: | Clinical pharmacology
18 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XVI, 424 S. Ill., graph. Darst. |
| ISBN: | 0824788192 |
Internformat
MARC
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| 245 | 1 | 0 | |a Drug stereochemistry |b analytical methods and pharmacology |c ed. by Irving W. Wainer ... |
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| 264 | 1 | |a New York, NY u.a. |b Dekker |c 1993 | |
| 300 | |a XVI, 424 S. |b Ill., graph. Darst. | ||
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Datensatz im Suchindex
| _version_ | 1804123880096268288 |
|---|---|
| adam_text | DRUG STEREOCHEMISTRY ANALYTICAL METHODS AND PHARMACOLOGY SECOND EDITION,
REVISED AND EXPANDED EDITED BY IRVING W.VIFAINER MCGHI UNIVERSITY AND
MONTREAL GENERAL HOSPITAL MONTREAL, QUEBEC, CANADA MARCEL DEKKER, INC.
NEW YORK * BASEL * HONG KONG CONTENTS SERIES INTRODUCTION V PREFACE TO
THE SECOND EDITION IX PREFACE TO THE FIRST EDITION XI CONTRIBUTORS XV I.
INTRODUCTION 1. THE EARLY HISTORY OF STEREOCHEMISTRY: FROM THE DISCOVERY
OF MOLECULAR ASYMMETRY AND THE FIRST RESOLUTION OF A RACEMATE BY PASTEUR
TO THE ASYMMETRICAL CHIRAL CARBON OF VAN T HOFF AND LE BEL 1 DENNIS E.
DRAYER 2. STEREOCHEMICAL TERMS AND CONCEPTS: AN OVERVIEW 25 IRVING W.
WAINER AND ALICE A. MARCOTTE II. THE SEPARATION AND PREPARATION OF
STEREOCHEMICALLY PURE DRUGS 3. ENANTIOMER ANALYSIS BY COMPETITIVE
BINDING METHODS 35 C. EDGAR COOK 4. INDIRECT METHODS FOR THE
CHROMATOGRAPHIC RESOLUTION OF DRUG ENANTIOMERS: SYNTHESIS AND SEPARATION
OF DIASTEREOMERIC DERIVATIVES 65 JOSEPH GAL 5. THE DIRECT RESOLUTION OF
ENANTIOMERIC DRUGS BY CHIRAL- PHASE GAS CHROMATOGRAPHY 107 WILFRIED A.
KONIG 6. HPLC CHIRAL STATIONARY PHASES FOR THE STEREOCHEMICAL RESOLUTION
OF ENANTIOMERIC COMPOUNDS: THE CURRENT STATE OF THE ART 139 IRVING W.
WAINER XIII XIV CONTENTS 7. SYNTHESIS OF ENANTIOMERICALLY PURE DRUGS 183
JOHN W. SCOTT 8. ENZYMATIC SYNTHESIS AND RESOLUTION OF ENANTIOMERICALLY
PURE COMPOUNDS 213 DAVID I. STIRLING III. PHARMACOKINETIC AND
PHARMACODYNAMIC DIFFERENCES BETWEEN DRUG STEREOISOMERS 9.
STEREOSELECTIVE BIOTRANSFORMATION:TOXICOLOGICAL CONSEQUENCES AND
IMPLICATIONS 245 NICO P. E. VERTNEULEN AND JOHAN M. TE KOPPELE 10.
STEREOSELECTIVE TRANSPORT OF DRUGS ACROSS EPITHELIA 281 RONDA J. OTT AND
KATHLEEN M. GIACOMINI 11. VERAPAMIL: A CHIRAL CHALLENGE TO THE
PHARMACOKINETIC AND PHARMACODYNAMIC ASSESSMENT OF BIOAVAILABILITY AND
BIOEQUIVALENCE 315 JAMES A. LONGSTRETH 12. ENANTIOSELECTIVE BINDING OF
DRUGS TO PLASMA PROTEINS 337 TERENCE A. G. NOCTOR IV. PERSPECTIVES ON
THE USE OF STEREOCHEMICALLY PURE DRUGS 13. FDA PERSPECTIVE ON THE
DEVELOPMENT OF NEW STEREOISOMERIC DRUGS: CHEMISTRY, MANUFACTURING, AND
CONTROL ISSUES 365 WILSON H. DE CAMP 14. STEREOCHEMICALLY PURE DRUGS: AN
OVERVIEW 375 FAKHREDDIN JAMALI 15. STEREOISOMERIC DRUGS IN THERAPEUTICS:
CLINICAL PERSPECTIVES 385 DARRELL R. ABERNETHY AND NABIL S. ANDRAWIS 16.
DEVELOPMENT OF STEREOISOMERIC DRUGS: AN INDUSTRIAL PERSPECTIVE 399
MITCHELL N. CAYEN INDEX 411
|
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| edition | 2. ed., rev. and expanded |
| format | Book |
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| genre_facet | Aufsatzsammlung Stereoisometrie |
| id | DE-604.BV009541091 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T17:36:48Z |
| institution | BVB |
| isbn | 0824788192 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-006301777 |
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| physical | XVI, 424 S. Ill., graph. Darst. |
| publishDate | 1993 |
| publishDateSearch | 1993 |
| publishDateSort | 1993 |
| publisher | Dekker |
| record_format | marc |
| series | Clinical pharmacology |
| series2 | Clinical pharmacology |
| spelling | Drug stereochemistry analytical methods and pharmacology ed. by Irving W. Wainer ... 2. ed., rev. and expanded New York, NY u.a. Dekker 1993 XVI, 424 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Clinical pharmacology 18 Stereochemie (DE-588)4129569-9 gnd rswk-swf Struktur-Aktivitäts-Beziehung (DE-588)4183784-8 gnd rswk-swf Arzneimittel (DE-588)4003115-9 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Stereoisometrie gnd rswk-swf Struktur-Aktivitäts-Beziehung (DE-588)4183784-8 s Arzneimittel (DE-588)4003115-9 s DE-604 Stereochemie (DE-588)4129569-9 s Stereoisometrie f Wainer, Irving W. 1944- Sonstige (DE-588)1058402625 oth Clinical pharmacology 18 (DE-604)BV000010647 18 GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=006301777&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Drug stereochemistry analytical methods and pharmacology Clinical pharmacology Stereochemie (DE-588)4129569-9 gnd Struktur-Aktivitäts-Beziehung (DE-588)4183784-8 gnd Arzneimittel (DE-588)4003115-9 gnd |
| subject_GND | (DE-588)4129569-9 (DE-588)4183784-8 (DE-588)4003115-9 (DE-588)4143413-4 |
| title | Drug stereochemistry analytical methods and pharmacology |
| title_auth | Drug stereochemistry analytical methods and pharmacology |
| title_exact_search | Drug stereochemistry analytical methods and pharmacology |
| title_full | Drug stereochemistry analytical methods and pharmacology ed. by Irving W. Wainer ... |
| title_fullStr | Drug stereochemistry analytical methods and pharmacology ed. by Irving W. Wainer ... |
| title_full_unstemmed | Drug stereochemistry analytical methods and pharmacology ed. by Irving W. Wainer ... |
| title_short | Drug stereochemistry |
| title_sort | drug stereochemistry analytical methods and pharmacology |
| title_sub | analytical methods and pharmacology |
| topic | Stereochemie (DE-588)4129569-9 gnd Struktur-Aktivitäts-Beziehung (DE-588)4183784-8 gnd Arzneimittel (DE-588)4003115-9 gnd |
| topic_facet | Stereochemie Struktur-Aktivitäts-Beziehung Arzneimittel Aufsatzsammlung Stereoisometrie |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=006301777&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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