Investigation into the self-sufficiency of the Federal Republic of Germany with regard to blood and blood products as compared to selected European countries (Great Britain, Sweden, The Netherlands) with particular reference to the therapeutic standard in the Federal Republic of Germany:
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Book |
| Language: | German |
| Published: |
Würzburg
Triltsch
1993
|
| Series: | Institut für Gesundheits-System-Forschung <Kiel>: Schriftenreihe
40 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | Literaturverz. - Beitr. teilw. dt., teilw. engl. |
| Physical Description: | 284 S. in getr. Zählung |
| ISBN: | 3878250444 |
Staff View
MARC
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| 245 | 1 | 0 | |a Investigation into the self-sufficiency of the Federal Republic of Germany with regard to blood and blood products as compared to selected European countries (Great Britain, Sweden, The Netherlands) with particular reference to the therapeutic standard in the Federal Republic of Germany |c Lars Chr. Kyburg ; Peter K. Schädlich |
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Record in the Search Index
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| adam_text | Contents 5
Contents
Preface 3
Introductory remarks 11
Summary 13
Abridged version 15
1 Background and objectives 25
2 Procedure 27
2.1 Outline of the problem 27
2.2 Method 29
2.2.1 Obtaining objective information 29
2.2.2 Definition of the degree of self sufficiency 30
2.2.3 Number of inhabitants 31
2.3 Material and method 31
2.3.1 Cooperation with external institutions and organisations 31
2.3.2 Internal organisation structure 33
2.3.3 Developing the questionnaire 33
2.3.4 Methodology of the analysis 35
2.4 Course of the investigation 37
2.4.1 Federal Republic of Germany 37
2.4.2 Reference countries 39
3 Results 42
3.1 Introduction 42
3.2 Factors of self sufficiency 43
3.2.1 Structure of and basic conditions for blood and plasma collection 43
3.2.1.1 Organisation and yield 43
3.2.1.2 Compensation, funding of blood and plasma donation services
and advertising 47
3.2.1.3 Donors 50
3.2.2 Usage of the blood and plasma yielded 54
3.2.3 Processing technology and fractionation capacity 57
3.2.4 Therapy of haemophilia 60
3.2.4.1 Information and data 60
3.2.4.2 Prevalence and severity of illness 61
6 Contents
3.2.4.3 Number of haemophiliacs and treatment centres 63
3.2.4.4 Therapeutic standard 68
3.2.4.5 Current research situation 78
3.2.4.6 Legislation governing the treatment of haemophiliacs 78
3.2.5 Pricing and costs of selected products 79
3.3 Degree of self sufficiency 80
3.3.1 Import and export 80
3.3.1.1 Imports 80
3.3.1.2 Export 83
3.3.2 Degree of self sufficiency 85
3.4 Additional comments and explanations given by the German
experts in this study 89
4 Discussion and recommendations 92
4.1 Discussion 92
4.2 Recommendations 95
5 Bibliography 99
5.1 Primary sources 99
5.2 Secondary sources 100
Contents 7
Appendix 1 List of interviewees
Appendix 2 Consensus recommendations for the treatment
of haemophiliacs in Germany
Appendix 3 Interviewleitfaden zum Gutachten Untersuchung der
Selbstversorgung der Bundesrepublik Deutschland mit
Blut und Blutprodukten im Vergleich zur Situation
bei drei ausgewahlten europaischen Landern (Schweden,
Niederlande, GroRbritannien) unter besonderer Beriick
sichtigung des Therapiestandards in der Bundesrepublik
Appendix 4 Questionnaire Investigation into the self sufficiency
of the Federal Republic of Germany with regard to blood
and blood products as compared to selected European
countries (Great Britain, Sweden, The Netherlands) with
particular reference to the therapeutic standard in the
Federal Republic of Germany
Appendix 5 Absolute figures used to calculate the quotients in Tables
1 to 4, 7, 14, 16, 17 and 19 from Section 3 Results
Figures
Figure 1 Plasma management 86
8 Tables
Tables
Table 1 Yield of human blood per country in 1991 45
Table 2 Yield of plasma per country in 1991 47
Table 3 Usage of the human blood and components per country in 1991 54
Table 4 Application of the total domestic yield of plasma per country
for 1991 56
Table 5 Fractionation techniques in each country in 1991 58
Table 6 Factor VIII and albumin yield according to country for 1991 59
Table 7 Fractionation capacity according to country for 1991 60
Table 8 Number of haemophiliacs per country in 1991 63
Table 9 Age distribution of the registered haemophiliacs (A and B) in the
Federal Republic of Germany, Great Britain and The Netherlands 68
Table 10 Therapy objectives underlying the treatment of patients with
haemophilia A 70
Table 11 Factor VIII dosage in IU/kg body weight per indication,
time intervals between the single dosages and duration of
the factor VIII substitution process for all four countries 73
Table 12 Factor IX dosage in IU/kg body weight per indication,
time intervals between the single dosages and duration of
the factor IX substitution process for all four countries 74
Table 13 Percentage of the main preparations used in the treatment of
haemophilia B for each country 75
Table 14 Consumption of coagulation factors per inhabitant for the
year 1991 according to country 76
Table 15 Origin of the imported plasma, plasma products and erythrocyte
concentrates for each country for 1991 81
Table 16 Amount of plasma and plasma products imported by each country
in 1991 82
Table 17 Export quota of plasma and selected plasma products for the four
countries in 1991 84
Table 18 Origin and fractionation of plasma for factor VIII for domestic
requirements 87
Table 19 Degree of self sufficiency with factor VIII, variants I to III
according to country in 1991 87
|
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| id | DE-604.BV008308666 |
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| indexdate | 2024-07-09T17:18:03Z |
| institution | BVB |
| isbn | 3878250444 |
| language | German |
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| series | Institut für Gesundheits-System-Forschung <Kiel>: Schriftenreihe |
| series2 | Institut für Gesundheits-System-Forschung <Kiel>: Schriftenreihe |
| spelling | Kyburg, Lars Chr. Verfasser aut Investigation into the self-sufficiency of the Federal Republic of Germany with regard to blood and blood products as compared to selected European countries (Great Britain, Sweden, The Netherlands) with particular reference to the therapeutic standard in the Federal Republic of Germany Lars Chr. Kyburg ; Peter K. Schädlich Würzburg Triltsch 1993 284 S. in getr. Zählung txt rdacontent n rdamedia nc rdacarrier Institut für Gesundheits-System-Forschung <Kiel>: Schriftenreihe 40 Literaturverz. - Beitr. teilw. dt., teilw. engl. Blutkonserve (DE-588)4146080-7 gnd rswk-swf Niederlande (DE-588)4042203-3 gnd rswk-swf Deutschland (DE-588)4011882-4 gnd rswk-swf Schweden (DE-588)4077258-5 gnd rswk-swf Großbritannien (DE-588)4022153-2 gnd rswk-swf Deutschland (DE-588)4011882-4 g Blutkonserve (DE-588)4146080-7 s Großbritannien (DE-588)4022153-2 g DE-604 Schweden (DE-588)4077258-5 g Niederlande (DE-588)4042203-3 g Schädlich, Peter K. Verfasser aut Institut für Gesundheits-System-Forschung <Kiel>: Schriftenreihe 40 (DE-604)BV001304973 40 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=005488834&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Kyburg, Lars Chr Schädlich, Peter K. Investigation into the self-sufficiency of the Federal Republic of Germany with regard to blood and blood products as compared to selected European countries (Great Britain, Sweden, The Netherlands) with particular reference to the therapeutic standard in the Federal Republic of Germany Institut für Gesundheits-System-Forschung <Kiel>: Schriftenreihe Blutkonserve (DE-588)4146080-7 gnd |
| subject_GND | (DE-588)4146080-7 (DE-588)4042203-3 (DE-588)4011882-4 (DE-588)4077258-5 (DE-588)4022153-2 |
| title | Investigation into the self-sufficiency of the Federal Republic of Germany with regard to blood and blood products as compared to selected European countries (Great Britain, Sweden, The Netherlands) with particular reference to the therapeutic standard in the Federal Republic of Germany |
| title_auth | Investigation into the self-sufficiency of the Federal Republic of Germany with regard to blood and blood products as compared to selected European countries (Great Britain, Sweden, The Netherlands) with particular reference to the therapeutic standard in the Federal Republic of Germany |
| title_exact_search | Investigation into the self-sufficiency of the Federal Republic of Germany with regard to blood and blood products as compared to selected European countries (Great Britain, Sweden, The Netherlands) with particular reference to the therapeutic standard in the Federal Republic of Germany |
| title_full | Investigation into the self-sufficiency of the Federal Republic of Germany with regard to blood and blood products as compared to selected European countries (Great Britain, Sweden, The Netherlands) with particular reference to the therapeutic standard in the Federal Republic of Germany Lars Chr. Kyburg ; Peter K. Schädlich |
| title_fullStr | Investigation into the self-sufficiency of the Federal Republic of Germany with regard to blood and blood products as compared to selected European countries (Great Britain, Sweden, The Netherlands) with particular reference to the therapeutic standard in the Federal Republic of Germany Lars Chr. Kyburg ; Peter K. Schädlich |
| title_full_unstemmed | Investigation into the self-sufficiency of the Federal Republic of Germany with regard to blood and blood products as compared to selected European countries (Great Britain, Sweden, The Netherlands) with particular reference to the therapeutic standard in the Federal Republic of Germany Lars Chr. Kyburg ; Peter K. Schädlich |
| title_short | Investigation into the self-sufficiency of the Federal Republic of Germany with regard to blood and blood products as compared to selected European countries (Great Britain, Sweden, The Netherlands) with particular reference to the therapeutic standard in the Federal Republic of Germany |
| title_sort | investigation into the self sufficiency of the federal republic of germany with regard to blood and blood products as compared to selected european countries great britain sweden the netherlands with particular reference to the therapeutic standard in the federal republic of germany |
| topic | Blutkonserve (DE-588)4146080-7 gnd |
| topic_facet | Blutkonserve Niederlande Deutschland Schweden Großbritannien |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=005488834&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV001304973 |
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