Percutaneous local anaesthesia:
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
New York u.a.
Ellis Horwood
1993
|
| Edition: | 1. publ. |
| Series: | Ellis Horwood series in pharmaceutical technology
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | 270 S. zahlr. graph. Darst. |
| ISBN: | 0136563724 |
Staff View
MARC
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| 245 | 1 | 0 | |a Percutaneous local anaesthesia |c David Woolfson and Dermot McCafferty |
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| 264 | 1 | |a New York u.a. |b Ellis Horwood |c 1993 | |
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| 650 | 4 | |a Anesthesia, Local |x methods | |
| 650 | 4 | |a Local anesthesia | |
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Record in the Search Index
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| adam_text | PERCUTANEOUS LOCAL ANAESTHESIA DAVID WOOLFSON AND DERMOT MCCAFFERTY BOTH
OF THE SCHOOL OF PHARMACY THE QUEEN S UNIVERSITY OF BELFAST ELLIS
HORWOOD NEW YORK LONDON TORONTO SYDNEY TOKYO SINGAPORE TABLE OF CONTENTS
PREFACE 9 1 THE NEED FOR EFFECTIVE PERCUTANEOUS LOCAL ANAESTHESIA 1.1
HISTORICAL DEVELOPMENT OF PERCUTANEOUS LOCAL ANAESTHESIA 12 1.2
PERCUTANEOUS LOCAL ANAESTHESIA: THE WAY FORWARD 15 2 PAIN 2.1 CUTANEOUS
SENSORY NETWORK 19 2.2 PAIN PERCEPTION 23 2.2.1 GATE CONTROL THEORY 23
2.3 EXPERIMENTAL PAIN INDUCTION 26 2.3.1 PAIN THRESHOLD 27 2.3.2 METHODS
OF PAIN INDUCTION 29 2.4 PAIN PERCEPTION IN CHILDREN 36 2.5 MEDICALLY
INDUCED PAIN IN CHILDREN 40 2.6 MEASUREMENT AND EVALUATION OF PAIN IN
CHILDREN 45 2.6.1 COGNITIVE PARAMETER OF PAIN 46 2.7 CONCLUSIONS 48
REFERENCES 49 3 LOCAL ANAESTHETICS 3.1 A SHORT HISTORY OF LOCAL
ANAESTHETICS 54 3.2 CLASSIFICATION 56 3.2.1 NOMENCLATURE 56 3.3
STRUCTURAL CHARACTERISTICS 60 3.4 PHYSICOCHEMICAL PROPERTIES 63 3.5
MECHANISM OF CONDUCTION BLOCKADE 67 3.5.1 NERVE DEPOLARISATION 67 3.5.2
IMPULSE CONDUCTION 68 3.5.3 REVERSIBLE IMPULSE BLOCKADE 69 TABLE OF
CONTENTS 3.6 CLINICAL CHARACTERISTICS OF LOCAL ANAESTHETICS 71 3.6.1
POTENCY 71 3.6.2 SPEED OF ONSET 73 3.6.3 DURATION OF ANAESTHETIC EFFECT
74 3.6.4 VASOACTIVITY 75 3.7 SYSTEMIC TOXICITY 77 3.7.1 SYSTEMIC
REACTIONS 80 3.8 LOCAL ADVERSE REACTIONS 81 3.9 METABOLISM 82 3.10
ROUTES OF ADMINISTRATION 84 3.10.1 NERVE BLOCK 84 3.10.2 LOCAL
INFILTRATION 85 3.10.3 TOPICAL (SURFACE) ANAESTHESIA 86 3.11 LOCAL
ANAESTHETICS FOR PERCUTANEOUS ABSORPTION 86 3.11.1 AMETHOCAINE 87 3.11.2
LIGNOCAINE 87 3.11.3 PRILOCAINE 88 3.11.4 KETOCAINE 88 3.11.5
MISCELLANEOUS AGENTS 89 REFERENCES 89 PERCUTANEOUS ABSORPTION OF LOCAL
ANAESTHETICS 4.1 PERCUTANEOUS ABSORPTION AND TRANSDERMAL DRUG DELIVERY
95 4.2 SKIN ANATOMY: SIGNIFICANCE FOR PERCUTANEOUS ABSORPTION 96 4.2.1
THEEPIDERMIS 97 4.2.2 THEDERMIS 100 4.2.3 SKIN APPENDAGES 100 4.3
POSSIBLE ROUTES TO PERCUTANEOUS LOCAL ANAESTHESIA 101 4.3.1 MODELS OF
PERCUTANEOUS ABSORPTION 102 4.3.2 TRANSPORT OF LOCAL ANAESTHETICS
THROUGH THE STRATUM COMEUM: THE TWO-COMPARTMENT MODEL 107 4.3.3
PERCUTANEOUS ABSORPTION OF AMETHOCAINE: EFFECT ON STRATUM CORNEUM LIPIDS
110 4.4 CUTANEOUS METABOLISM OF LOCAL ANAESTHETICS 114 4.5 IN VITRO
METHODOLOGY FOR ASSESSMENT OF THE PERCUTANEOUS PENETRATION OF LOCAL
ANAESTHETICS 118 4.5.1 THE INFINITE DOSE TECHNIQUE 118 4.5.2 THE FINITE
DOSE TECHNIQUE 119 4.5.3 CHOICE OF BARRIER MEMBRANE FOR IN VITRO
PENETRATION STUDIES ON LOCAL ANAESTHETICS 120 4.6 PERCUTANEOUS
PENETRATION CHARACTERISTICS OF LOCAL ANAESTHETICS 122 4.6.1 PERCUTANEOUS
PENETRATION CHARACTERISTICS OF BENZOCAINE 123 4.6.2 PERCUTANEOUS
PENETRATION CHARACTERISTICS OF LIGNOCAINE ....124 4.6.3 PERCUTANEOUS
PENETRATION CHARACTERISTICS OF AMETHOCAINE THROUGH VARIOUS BARRIER
MEMBRANES 126 TABLE OF CONTENTS 4.6.3.1 AMETHOCAINE PENETRATION
CHARACTERISTICS THROUGH HUMAN AND PORCINE WHOLE SKIN, AND THROUGH HUMAN
EPIDERMIS 126 4.6.3.2 INFLUENCE OF APPLICATION TIME ON AMETHOCAINE SKIN
PENETRATION CHARACTERISTICS 131 4.6.3.3 PENETRATION CHARACTERISTICS OF
LIGNOCAINE AND PRILOCAINE BASES FROM A EUTECTIC MIXTURE 134 4.7
NON-INVASIVE MONITORING OF PERCUTANEOUS LOCAL ANAESTHESIA IN VIVO 135
4.8 CLINICAL FACTORS AFFECTING THE PERCUTANEOUS ABSORPTION OF LOCAL
ANAESTHETICS 138 REFERENCES 141 FORMULATION OF LOCAL ANAESTHETICS FOR
PERCUTANEOUS DELIVERY 5. 1 DERMATOLOGICAL VEHICLES FOR THE PERCUTANEOUS
DELIVERY OF LOCAL ANAESTHETICS 149 5.2 SEMI-SOLID VEHICLES 150 5.2.1
OINTMENT VEHICLES 151 5.2.2 CREAM VEHICLES 153 5.2.3 GEL VEHICLES 155
5.2.3.1 CELLULOSE ETHERS 155 5.2.3.2 CARBOMERS 156 5.3 FORMULATION OF
LIPOPHILIC ANAESTHETIC BASES IN AQUEOUS SYSTEMS 158 5.3.1 EUTECTIC
MIXTURE OF LOCAL ANAESTHETICS 158 5.3.2 THE AMETHOCAINE PHASE-CHANGE
SYSTEM 166 5.3.3 LIPOSOMAL PERCUTANEOUS ANAESTHETIC SYSTEMS 171 5.3.4
SOLUTION SYSTEMS 174 5.4 IONTOPHORESIS 175 5.4.1 CHEMICAL FACTORS
INFLUENCING IONTOPHORETIC DRUG TRANSPORT 176 5.4.2 ELECTRICAL FACTORS
INFLUENCING IONTOPHORETIC DRUG TRANSPORT 176 5.4.3 PERCUTANEOUS LOCAL
ANAESTHESIA BY IONTOPHORESIS 178 5.5 PHONOPHORESIS OF LOCAL ANAESTHETICS
185 5.6 ENHANCEMENT OF THE PERCUTANEOUS PENETRATION OF LOCAL
ANAESTHETICS BY CHEMICAL AGENTS 185 5.6.1 PENETRATION ENHANCERS 186
5.6.2 USE OF PENETRATION ENHANCERS WITH LOCAL ANAESTHETICS 189 5.7
STABILITY CONSIDERATIONS 192 5.7.1 STABILISATION OF LOCAL ANAESTHETICS
IN LIPOSOMES 193 5.7.2 STABILISATION OF THE AMETHOCAINE PHASE-CHANGE
SYSTEM 194 5.8 PRESERVATION OF PERCUTANEOUS LOCAL ANAESTHETIC SYSTEMS
195 REFERENCES 198 TABLE OF CONTENTS CLINICAL APPLICATIONS OF
PERCUTANEOUS LOCAL ANAESTHESIA 6.1 VENEPUNCTURE IN CHILDREN 204 6.2
VENEPUNCTURE IN ADULTS 214 6.3 PERCUTANEOUS LOCAL ANAESTHESIA WITH
PREMEDICATION 217 6.4 PAIN RELIEF DURING ARTERIAL CANNULATION 221 6.5
PAIN RELIEF DURING LUMBAR PUNCTURE 223 6.6 PAIN RELIEF FOR THE INSERTION
OF HAEMODIALYSIS CANNULAE AND PUNCTURES THROUGH SUBCUTANEOUS DRUG
RESERVOIRS 224 6.7 HARVESTING OF SPLIT SKIN GRAFTS USING PERCUTANEOUS
LOCAL ANAESTHESIA 225 6.8 PERCUTANEOUS LOCAL ANAESTHESIA FOR DEBRIDEMENT
IN LEG ULCER TREATMENT 232 6.9 TREATMENT OF MOLLUSCUM CONTAGIOSUM 235
6.10 CAUTERY OF GENITAL WARTS 238 6.11 POST-HERPETIC NEURALGIA 240 6.12
PAINFUL CONDITIONS OF THE EAR 241 6.13 LASER-INDUCED PAIN 245 6.14
MANIPULATION OF NASAL FRACTURES 248 6.15 TOPICAL ANAESTHESIA OF THE
GINGIVAL MUCOSA 249 6.16 ALLEVIATION OF PAIN DUE TO RETROBULBAR
INJECTION 249 6.17 TOURNIQUET PAIN 250 6.18 EXPERIMENTALLY INDUCED
PRURITIS 252 6.19 EXTRA-CORPOREAL SHOCK WAVE LITHOTRIPSY 253 6.20
ADVERSE REACTIONS DUE TO PERCUTANEOUS LOCAL ANAESTHESIA 253 6.21
CONCLUSIONS 261 REFERENCES 261 INDEX 266
|
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| illustrated | Illustrated |
| indexdate | 2024-07-09T17:12:14Z |
| institution | BVB |
| isbn | 0136563724 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-005239228 |
| oclc_num | 27854744 |
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| owner | DE-355 DE-BY-UBR |
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| physical | 270 S. zahlr. graph. Darst. |
| publishDate | 1993 |
| publishDateSearch | 1993 |
| publishDateSort | 1993 |
| publisher | Ellis Horwood |
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| series2 | Ellis Horwood series in pharmaceutical technology |
| spelling | Woolfson, David Verfasser aut Percutaneous local anaesthesia David Woolfson and Dermot McCafferty 1. publ. New York u.a. Ellis Horwood 1993 270 S. zahlr. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Ellis Horwood series in pharmaceutical technology Anesthésie locale Voie cutanée Administration, Cutaneous Anesthesia, Local methods Local anesthesia Skin absorption Lokalanästhesie (DE-588)4036262-0 gnd rswk-swf Lokalanästhesie (DE-588)4036262-0 s DE-604 MacCafferty, Dermot Verfasser aut GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=005239228&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Woolfson, David MacCafferty, Dermot Percutaneous local anaesthesia Anesthésie locale Voie cutanée Administration, Cutaneous Anesthesia, Local methods Local anesthesia Skin absorption Lokalanästhesie (DE-588)4036262-0 gnd |
| subject_GND | (DE-588)4036262-0 |
| title | Percutaneous local anaesthesia |
| title_auth | Percutaneous local anaesthesia |
| title_exact_search | Percutaneous local anaesthesia |
| title_full | Percutaneous local anaesthesia David Woolfson and Dermot McCafferty |
| title_fullStr | Percutaneous local anaesthesia David Woolfson and Dermot McCafferty |
| title_full_unstemmed | Percutaneous local anaesthesia David Woolfson and Dermot McCafferty |
| title_short | Percutaneous local anaesthesia |
| title_sort | percutaneous local anaesthesia |
| topic | Anesthésie locale Voie cutanée Administration, Cutaneous Anesthesia, Local methods Local anesthesia Skin absorption Lokalanästhesie (DE-588)4036262-0 gnd |
| topic_facet | Anesthésie locale Voie cutanée Administration, Cutaneous Anesthesia, Local methods Local anesthesia Skin absorption Lokalanästhesie |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=005239228&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT woolfsondavid percutaneouslocalanaesthesia AT maccaffertydermot percutaneouslocalanaesthesia |