The in vivo study of drug action: principles and applications of kinetic-dynamic modelling
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Amsterdam u.a.
Elsevier
1992
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XIX, 429 S. graph. Darst. |
| ISBN: | 0444813705 |
Staff View
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Record in the Search Index
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| adam_text | THE IN VIVO STUDY OF DRUG ACTION PRINCIPLES AND APPLICATIONS OF
KINETIC-DYNAMIC MODELLING EDITORS C.J. VAN BOXTEL ACADEMIC MEDICAL
CENTRE, MEIBERGDREEF 9 1105 AZ AMSTERDAM, THE NETHERLANDS N.H.G. HOLFORD
UNIVERSITY OF AUCKLAND AUCKLAND, NEW ZEALAND M. DANHOF UNIVERSITY OF
LEIDEN, SYLVIUS LABORATORY, P.O.BOX 9503 2300 RA LEIDEN, THE NETHERLANDS
ELSEVIER AMSTERDAM * LONDON * NEW YORK * TOKYO 1992 CONTENTS PREFACE V
LIST OF CONTRIBUTORS VII INTRODUCTION. KINETICS OF DRUG ACTION - AN
OVERVIEW G. LEVY XIII PART 1. INTRODUCTION 1. THE STUDY OF DRUG-RECEPTOR
INTERACTION IN IN VIVO SYSTEMS T.P. KENAKIN 1 2. MODELS OF DRUG ACTION:
EXPERIMENTAL DESIGN ISSUES W.A. COLBURN AND M.A. ELDON 17 3.
PHARMACOKINETIC COMPLEXITIES OF PHARMACODYNAMIC STUDIES IN VIVO M.
DANHOF, J.W. MANDEMA AND A.M. STIJNEN 31 4. PARAMETRIC MODELS OF THE
TIME COURSE OF DRUG ACTION N.H.G. HOLFORD 61 5. SEMIPARAMETRIC MODELS OF
THE TIME COURSE OF DRUG ACTION D. VEROTTA AND L.B. SHEINER 71 6.
COMBINED DRUG ACTION C.J. VAN BOXTEL AND R.E. JONKERS 93 PART 2. DRUG
EFFECTS ON THE NERVOUS SYSTEM 7. KINETICS AND DYNAMICS OF DRUG EFFECTS
ON THE NERVOUS SYSTEM: AN INTRODUCTION J. DINGEMANSE 113 8. MEASUREMENT
AND MODELING OF ANALGESIC DRUG EFFECT V L.K. PAALZOW 1.33 9.
PHARMACODYNAMIC MEASUREMENT AND MODELLING OF ANESTHETIC DEPTH D.R.
STANSKI 155 10. PHARMACOKINETIC-PHARMACODYNAMIC MODELLING WITH
ANTICONVULSANTS IN ANIMAL MODELS AND IN HUMANS M. DANHOF, R.A. VOSKUYL
AND A. HOOGERKAMP 181 11. KINETIC-DYNAMIC MODELLING OF NEUROMUSCULAR
BLOCKADE C.A. SHANKS 205 XLL PART 3. CARDIOVASCULAR DRUG ACTION 12.
KINETICS AND DYNAMICS OF CARDIOVASCULAR DRUG ACTION: INTRODUCTION H.A.J.
STRUYKER BOUDIER . . . 219 13. AN INDIVIDUALISED APPROACH TO
OPTIMISING LONG-TERM ANTIHYPERTENSIVE THERAPY USING CONCENTRATION-EFFECT
ANALYSIS P.A. MEREDITH, H.L. ELLIOTT AND J.L. REID 233 14. DIURETIC
PHARMACOKINETICS AND PHARMACODYNAMICS D.C. BRATER 253 15. ANTIARRHYTHMIC
DRUGS AND CARDIAC GLYCOSIDES A. WELLSTEIN, R.L. WOOSLEY AND S.L.
SCHWARTZ 277 16. PHARMACOKINETICS AND PHARMACODYNAMICS OF ANTICOAGULANT
DRUGS T.D. BJORNSSON AND A. TERZIC 303 PART 4. MISCELLANEOUS 17.
ANTI-INFECTIVE DRUGS N.J. WHITE AND TM.E. DAVIS 313 18. ANTIHISTAMINES
J.J.P. HEYKANTS, E. SNOECK, E AWOUTERS AND A. VAN PEER 337 19.
PHARMACOKINETIC-PHARMACODYNAMIC MODELLING OF GLUCOCORTICOSTEROID ACTION
C.J. VAN BOXTEL AND B. OOSTERHUIS 357 20. CYTOTOXICS AND IRREVERSIBLE
EFFECTS M.J. MOORE AND J.J. THEISSEN 377 PART 5. DRUG DEVELOPMENT 21.
POPULATION PHARMACODYNAMICS AND DRUG DEVELOPMENT N.H.G. HOLFORD AND C.C.
PECK 401 ^SUBJECT INDEX 415
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| isbn | 0444813705 |
| language | English |
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| physical | XIX, 429 S. graph. Darst. |
| publishDate | 1992 |
| publishDateSearch | 1992 |
| publishDateSort | 1992 |
| publisher | Elsevier |
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| spelling | The in vivo study of drug action principles and applications of kinetic-dynamic modelling eds.: C. J. van Boxtel ... Amsterdam u.a. Elsevier 1992 XIX, 429 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Pharmacokinetics cabt Pharmakokinetik (DE-588)4115557-9 gnd rswk-swf Pharmakodynamik (DE-588)4174134-1 gnd rswk-swf Pharmakokinetik (DE-588)4115557-9 s DE-604 Pharmakodynamik (DE-588)4174134-1 s Boxtel, Chris J. van Sonstige oth GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=005229003&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | The in vivo study of drug action principles and applications of kinetic-dynamic modelling Pharmacokinetics cabt Pharmakokinetik (DE-588)4115557-9 gnd Pharmakodynamik (DE-588)4174134-1 gnd |
| subject_GND | (DE-588)4115557-9 (DE-588)4174134-1 |
| title | The in vivo study of drug action principles and applications of kinetic-dynamic modelling |
| title_auth | The in vivo study of drug action principles and applications of kinetic-dynamic modelling |
| title_exact_search | The in vivo study of drug action principles and applications of kinetic-dynamic modelling |
| title_full | The in vivo study of drug action principles and applications of kinetic-dynamic modelling eds.: C. J. van Boxtel ... |
| title_fullStr | The in vivo study of drug action principles and applications of kinetic-dynamic modelling eds.: C. J. van Boxtel ... |
| title_full_unstemmed | The in vivo study of drug action principles and applications of kinetic-dynamic modelling eds.: C. J. van Boxtel ... |
| title_short | The in vivo study of drug action |
| title_sort | the in vivo study of drug action principles and applications of kinetic dynamic modelling |
| title_sub | principles and applications of kinetic-dynamic modelling |
| topic | Pharmacokinetics cabt Pharmakokinetik (DE-588)4115557-9 gnd Pharmakodynamik (DE-588)4174134-1 gnd |
| topic_facet | Pharmacokinetics Pharmakokinetik Pharmakodynamik |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=005229003&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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