Molecular biology of DNA topoisomerases and its application to chemotherapy: proceedings of the International Symposium on DNA Topoisomerases in Chemotherapy, Nagoya, Japan, November 18 - 20, 1991 (ISTOP 1991)
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| Format: | Conference Proceeding Book |
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| Language: | English |
| Published: |
Boca Raton u.a.
CRC Press
1993
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| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | 377 S. graph. Darst. |
| ISBN: | 0849349702 |
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9 MOLECULAR BIOLOGY DNA TOPOISOMERASES AND ITS APPLICATION TO
CHEMOTHERAPY PROCEEDINGS OF THE INTERNATIONAL SYMPOSIUM ON DNA
TOPOISOMERASES IN CHEMOTHERAPY NAGOYA, JAPAN, NOVEMBER 18-20, 1991
(ISTOP 1991) EDITED BY TOSHIWO ANDOH, PH.D. LABORATORY OF BIOCHEMISTRY
AICHI CANCER CENTER RESEARCH INSTITUTE NAGOYA, JAPAN HIDEO IKEDA, PH.D.
INSTITUTE OF MEDICAL SCIENCE, UNIVERSITY OF TOKYO TOKYO, JAPAN MASAO
OGURO, PH.D. DIVISION OF HEMATOLOGY AND CHEMOTHERAPY CHIBA CANCER CENTER
HOSPITAL CHIBA, JAPAN CRC PRESS BOCA RATON ANN ARBOR LONDON TOKYO
CONTENTS ISTOP ORGANIZATION PREFACE TRIBUTE KEYNOTE ADDRESS DNA
TOPOISOMERASES AS TARGETS OF THERAPEUTICS: A STRUCTURAL OVERVIEW 1 PAUL
R. CARON AND JAMES C. WANG I. GENETICS AND BIOLOGY OF DNA TOPOISOMERASES
CHAPTER 1 DNA GYRASE: STRUCTURE, MECHANISM AND INTERACTION WITH
ANTIBIOTICS 21 ANTHONY MAXWELL, JANID A. ALI, A.NDREW D. BATES, ASUNCION
CONTRERAS, ALISON J. HOWELLS, A.NDREW P. JACKSON, RICHARD J. REECE,
CHRISTOPHER J. R. WILLMOTT, GIDEON J. DAVIES, AND DALE B. WIGLEY CHAPTER
2 PURIFICATION AND CHARACTERIZATION OF DNA TOPOISOMERASE IV IN
ESCHERICHIA COLI 31 JUN-ICHI KATO AND HIDEO IKEDA CHAPTER 3 MULTIPLE DNA
GYRASE-LIKE GENES IN EUBACTERIA 39 WAI MUN HUANG CHAPTER 4 INVOLVEMENT
OF TYPE II DNA TOPOISOMERASES IN ILLEGITIMATE RECOMBINATION IN
ESCHERICHIA COLI: ANALYSES OF THE PARTIAL DIPLOID OF PHAGE T4 AND THE
SPECIALIZED TRANSDUCING PARTICLES OF PHAGE X 49 HIDEO IKEDA, MICHIYO
KUMAGAI, TERUHITO YAMASHITA, AND MASAAKI HONDA CHAPTER 5 FUNCTIONAL
DISSECTION OF DNA TOPOISOMERASE II 57 KAZUHIRO SHIOZAKI AND MITSUHIRO
YANAGIDA CHAPTER 6 CELL CYCLE-DEPENDENT PHOSPHORYLATION OF DNA
TOPOISOMERASE II AND MODIFICATION OF ITS ACTIVITY BY PHOSPHORYLATION 65
TAKEMI ENOMOTO, MASAFUMI SAIJO, KEIJI KIMURA, AND MICHIO UI CHAPTER 7
STRUCTURE AND EXPRESSION OF THE HUMAN DNA TOPOISOMERASE I GENE 77
NORBERT KUNZE, SUSANNE HEILAND, ROLF KNIPPERS, AND ARNDT RICHTER CHAPTER
8 SUPERCOILING FACILITATES THE ASSEMBLY OF ACTIVE CHROMATIN 87 SUSUMU
HIROSE AND REIKO OHBA CHAPTER 9 TECHNIQUES TO UNCOUPLE DNA BINDING,
CLEAVAGE, AND RELIGATION IN THE CATALYTIC CYCLES OF EUKARYOTIC
TOPOISOMERASE I AND II 95 JESPER Q. SVEJSTRUP, ANNI H. ANDERSEN, BENT K.
JAKOBSEN, ANNE D. JENSEN, BOE S. SORENSEN, JAN ALSNER, KENT
CHRISTIANSEN, AND OLE WESTERGAARD CHAPTER 10 REACTIVITY OF EUKARYOTIC
TYPE II TOPOISOMERASE WITH UNUSUAL DNA STRUCTURES 105 I. K. CHUNG, J. R.
SPITZNER, AND M. T. MULLER CHAPTER 11 DIFFERENTIAL EXPRESSION OF DNA
TOPOISOMERASE II ISOZYMES IN DEVELOPING RAT BRAIN 115 KIMIKO TSUTSUI,
KEN TSUTSUI, SHOSHIRO OKADA, TOSHIKIYO SHOHMORI, AND SHUJI SEKI CHAPTER
12 EXPRESSION OF HUMAN TYPE I AND II DNA TOPOISOMERASES AND THEIR
DERIVATIVES IN E.COLI 121 AKIHIKO KIKUCHI AND MITSUKO MIYAIKE II.
INHIBITORS OF MICROBIAL DNA TOPOISOMERASES AND DRUG RESISTANCE CHAPTER
13 QUINOLONE RESISTANCE MUTATIONS IN DNA GYRASE 135 SHINICHI NAKAMURA,
HIROAKI YOSHIDA, MAYUMI BOGAKI, MIKA NAKAMURA, AND TSUYOSHI KOJIMA
CHAPTER 14 DNA GYRASE: MECHANISM AND RESISTANCE TO 4-QUINOLONE
ANTIBACTERIAL AGENTS 145 L. MARK FISHER, MARK ORAM, AND SANTHA
SREEDHARAN CHAPTER 15 QUINOLONE-RESISTANCE IN PSEUDOMONAS AERUGINOSA 157
KEIJI HIRAI, HIDEYUKI FUKUDA, TAKASHI OKAZAKI, AND SHIZUKO IYOBE CHAPTER
16 ANTIBACTERIAL ACTIVITY OF NEW QUINOLONES AND THEIR MODES OF ACTION
167 KENICHI SATO, KAZUKI HOSHINO, MAYUMI TANAKA, ISAO HAYAKAWA, YASUAKI
OSADA, TAKESHI NISHINO, AND SUSUMU MITSUHASHI CHAPTER 17 MOLECULAR
MECHANISM OF DNA GYRASE INHIBITION BY QUINOLONE ANTIBACTERIAL AGENTS 177
LINUS L. SHEN III. INHIBITORS OF MAMMALIAN DNA TOPOISOMERASES AND DRUG
RESISTANCE CHAPTER 18 A NOVEL QUINOLONE WITH POTENT ACTIVITY AGAINST
EUKARYOTIC DNA TOPOISOMERASE II 189 MEGAN J. ROBINSON, SARAH H. ELSEA,
BARBARA A. MARTIN, THOMAS D. GOOTZ, PAUL R. MCGUIRK, JOYCE A. SUTCLIFF,
AND NEIL OSHEROFF CHAPTER 19 NEW MICROBIAL METABOLITES THAT INDUCE DNA
CLEAVABLE COMPLEX WITH MAMMALIAN TOPOISOMERASES 199 YOSHINORI YAMASHITA,
SHO-ZOU KAWADA, NOBORU FUJII, KATSUSHIGE GOMI, TOSHIMITSU TAKIGUCHI, AND
HIROFUMI NAKANO CHAPTER 20 MECHANISM OF ACTION OF NONCLEAVABLE
COMPLEX-FORMING TYPE OF TOPOISOMERASE II INHIBITORS,
BIS(2,6-DIOXOPIPERAZINE) DERIVATIVES 207 RYOGI ISHIDA, KAZUSHI TANABE,
TOSHIHARU NARITA, MAKOTO SATO, RYOGO YUI, KAZUHIKO R. UTSUMI, AND
TOSHIWO ANDOH CHAPTER 21 BASE SEQUENCE SELECTIVITY OF TOPOISOMERASE
INHIBITORS SUGGESTS A COMMON MODEL FOR DRUG ACTION 215 YVES POMMIER,
KURT W. KOHN, GIOVANNI CAPRANICO, AND CHRISTINE JAXEL CHAPTER 22
MECHANISM OF CAMPTOTHECIN RESISTANCE IN MAMMALIAN CELLS: MUTATION IN
TOPOISOMERASE I GENE AND ITS IMPLICATION IN ENZYMATIC FUNCTION 229
TOSHIWO ANDOH, HIRO-OMI TAMURA, CHIE KOHCHI, RYUTARO YAMADA, TOMOTAKE
IKEDA, OSAMU KOIWAI, YOSHIHIRO YASUI, MIWAKO NISHIZAWA, AND KOSUKE OKADA
CHAPTER 23 THE EFFECTS OF CAMPTOTHECIN ON EUKARYOTIC TOPOISOMERASE 1 237
JAMES J. CHAMPOUX CHAPTER 24 TOPOISOMERASE POISONS THAT OVERCOME
MDRL-MEDIATED RESISTANCE 247 ALLAN Y. CHEN, CHIANG YU, CHIA-CHUNG CHENG,
MILAN POTMESIL, MONROE E. WALL, MANSUKH C. WANI, AND LEROY F. LIU
CHAPTER 25 DRUG RESISTANCE TO DNA TOPOISOMERASE II-TARGETING AGENTS AND
DEVELOPMENT OF THE REVERSAL AGENTS 255 KIMITOSHI KOHNO, HIROSHI TAKANO,
KEN-ICHI MATSUO, AKIRA KIUE, SHIN-ICHI SATO, TAKESHI UCHIUMI, MIKI
MIYAZAKI, HIDEYUKI TANIMURA, SEIJI SATO, AND MICHIHIKO KUWANO CHAPTER 26
PHENOTYPIC PROPERTIES OF CHINESE HAMSTER LUNG CELLS RESISTANT TO DNA
TOPOISOMERASE II INHIBITORS 265 A. JACQUEMIN-SABLON, K. BOJANOWSKI,
M.-R. CASABIANCA-PIGNEDE, S. CREMIER, C. DELAPORTE, T. KHELIFA, B. RENE,
J.-M. SAUCIER, AND A. K. LARSEN CHAPTER 27 DISTRIBUTION OF TOPOISOMERASE
II AND ITS RESPONSE TO VM-26 IN DRUG-SENSITIVE AND -RESISTANT HUMAN
LEUKEMIC CELLS 275 WILLIAM T. BECK, MARY K. DANKS, AND JUDITH S.
WOLVERTON CHAPTER 28 PROBING MECHANISMS OF CELL KILLING AND RESISTANCE
TO ANTITOPOISOMERASE II AGENTS USING YEAST 287 J. L. NITISS, Y.-X. LIU,
AND M. JANNATIPOUR IV. PRECLINICAL AND CLINICAL STUDIES OF DNA
TOPOISOMERASE INHIBITORS CHAPTER 29 PRECLINICAL AND CLINICAL DEVELOPMENT
OF DNA TOPOISOMERASE I INHIBITORS IN THE UNITED STATES 301 MILAN
POTMESIL, B. C. GIOVANELLA, MONROE E. WALL, LEROY F. LIU, R. SILBER, J.
S. STEHLIN, MANSUKH C. WANI, AND H. HOCHSTER CHAPTER 30 IN VITRO
MODIFICATION OF CYTOCIDAL EFFECTS OF CPT-11 IN COMBINATION WITH DNA
TOPOISOMERASE II-RELATED AGENTS 313 MASAO OGURO AND YASUO SEKI CHAPTER
31 PHASE II STUDY OF CPT-11, A NEW DERIVATIVE OF CAMPTOTHECIN, ON
LEUKEMIA ANDLYMPHOMA 321 RYUZO OHNO, YUTAKA ARIYOSHI, SHIRO FUKUHARA,
KOSUKE OKADA, KIYOSHI TAKATSUKI, TOHRU MASAOKA, JUN KURAMOTO, MASAO
OGURO, MASANORI SHIMOYAMA, SHIMOYAMA SHIRAKAWA, MAKOTO OGAWA, KAZUO OTA,
AND CPT-11 STUDY GROUP ON HEMATOLOGICAL MALIGNANCY, JAPAN CHAPTER 32
CLINICAL EVALUATION OF CPT-11, A TOPOISOMERASE I INHIBITOR, IN LUNG
CANCER 329 MASAHIRO FUKUOKA, SHUNICHI NEGORO, MINORU TAKADA, NORIYUKI
MASUDA, HISANOBU NIITANI, AND TETSUO TAGUCHI CHAPTER 33 CLINICAL STUDIES
OF DNA TOPOISOMERASE I INHIBITOR (CPT-11) ON GYNECOLOGICAL CANCERS 337
COOPERATIVE STUDY GROUP OF CPT-11 ON GYNECOLOGICAL CANCERS* CHAPTER 34 A
PHASE II STUDY OF CPT-11, A NEW CAMPTOTHECIN DERIVATIVE, IN PATIENTS
WITH METASTATIC COLORECTAL CANCER 345 YASUHIRO SHIMADA, MASAHIRO
YOSHINO, AKIRA WAKUI, ISAO NAKAO, KOICHI FUTATSUKI, YUH SAKATA, MARIKO
KAMBE, TETSUO TAGUCHI, AND CPT-11 GASTROINTESTINAL CANCER STUDY GROUP
POSTER PRESENTATION 351 AUTHOR INDEX 363 INDEX 367 |
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| spelling | Molecular biology of DNA topoisomerases and its application to chemotherapy proceedings of the International Symposium on DNA Topoisomerases in Chemotherapy, Nagoya, Japan, November 18 - 20, 1991 (ISTOP 1991) ed. by Toshiwo Andoh ... Boca Raton u.a. CRC Press 1993 377 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Inhibitor (DE-588)4027007-5 gnd rswk-swf Chemotherapie (DE-588)4127083-6 gnd rswk-swf Pharmakologie (DE-588)4045687-0 gnd rswk-swf DNS-Topoisomerasen (DE-588)4333298-5 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1991 Nagoya gnd-content DNS-Topoisomerasen (DE-588)4333298-5 s DE-604 Inhibitor (DE-588)4027007-5 s Pharmakologie (DE-588)4045687-0 s Chemotherapie (DE-588)4127083-6 s Andoh, Toshiwo Sonstige oth International Symposium on DNA Topoisomerases in Chemotherapy 1991 Nagoya Sonstige (DE-588)5135140-7 oth GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=004493932&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Molecular biology of DNA topoisomerases and its application to chemotherapy proceedings of the International Symposium on DNA Topoisomerases in Chemotherapy, Nagoya, Japan, November 18 - 20, 1991 (ISTOP 1991) Inhibitor (DE-588)4027007-5 gnd Chemotherapie (DE-588)4127083-6 gnd Pharmakologie (DE-588)4045687-0 gnd DNS-Topoisomerasen (DE-588)4333298-5 gnd |
| subject_GND | (DE-588)4027007-5 (DE-588)4127083-6 (DE-588)4045687-0 (DE-588)4333298-5 (DE-588)1071861417 |
| title | Molecular biology of DNA topoisomerases and its application to chemotherapy proceedings of the International Symposium on DNA Topoisomerases in Chemotherapy, Nagoya, Japan, November 18 - 20, 1991 (ISTOP 1991) |
| title_auth | Molecular biology of DNA topoisomerases and its application to chemotherapy proceedings of the International Symposium on DNA Topoisomerases in Chemotherapy, Nagoya, Japan, November 18 - 20, 1991 (ISTOP 1991) |
| title_exact_search | Molecular biology of DNA topoisomerases and its application to chemotherapy proceedings of the International Symposium on DNA Topoisomerases in Chemotherapy, Nagoya, Japan, November 18 - 20, 1991 (ISTOP 1991) |
| title_full | Molecular biology of DNA topoisomerases and its application to chemotherapy proceedings of the International Symposium on DNA Topoisomerases in Chemotherapy, Nagoya, Japan, November 18 - 20, 1991 (ISTOP 1991) ed. by Toshiwo Andoh ... |
| title_fullStr | Molecular biology of DNA topoisomerases and its application to chemotherapy proceedings of the International Symposium on DNA Topoisomerases in Chemotherapy, Nagoya, Japan, November 18 - 20, 1991 (ISTOP 1991) ed. by Toshiwo Andoh ... |
| title_full_unstemmed | Molecular biology of DNA topoisomerases and its application to chemotherapy proceedings of the International Symposium on DNA Topoisomerases in Chemotherapy, Nagoya, Japan, November 18 - 20, 1991 (ISTOP 1991) ed. by Toshiwo Andoh ... |
| title_short | Molecular biology of DNA topoisomerases and its application to chemotherapy |
| title_sort | molecular biology of dna topoisomerases and its application to chemotherapy proceedings of the international symposium on dna topoisomerases in chemotherapy nagoya japan november 18 20 1991 istop 1991 |
| title_sub | proceedings of the International Symposium on DNA Topoisomerases in Chemotherapy, Nagoya, Japan, November 18 - 20, 1991 (ISTOP 1991) |
| topic | Inhibitor (DE-588)4027007-5 gnd Chemotherapie (DE-588)4127083-6 gnd Pharmakologie (DE-588)4045687-0 gnd DNS-Topoisomerasen (DE-588)4333298-5 gnd |
| topic_facet | Inhibitor Chemotherapie Pharmakologie DNS-Topoisomerasen Konferenzschrift 1991 Nagoya |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=004493932&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT andohtoshiwo molecularbiologyofdnatopoisomerasesanditsapplicationtochemotherapyproceedingsoftheinternationalsymposiumondnatopoisomerasesinchemotherapynagoyajapannovember18201991istop1991 AT internationalsymposiumondnatopoisomerasesinchemotherapynagoya molecularbiologyofdnatopoisomerasesanditsapplicationtochemotherapyproceedingsoftheinternationalsymposiumondnatopoisomerasesinchemotherapynagoyajapannovember18201991istop1991 |