Naturally occurring carcinogens of plant origin: toxicology, pathology and biochemistry
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Tokyo
Kodansha [u.a.]
1987
|
| Series: | Bioactive molecules
2 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | Literaturangaben |
| Physical Description: | XI, 234 S. Ill., graph. Darst. |
| ISBN: | 0444989722 4062021935 |
Staff View
MARC
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| 245 | 1 | 0 | |a Naturally occurring carcinogens of plant origin |b toxicology, pathology and biochemistry |c ed. by Iwao Hirono |
| 264 | 1 | |a Tokyo |b Kodansha [u.a.] |c 1987 | |
| 300 | |a XI, 234 S. |b Ill., graph. Darst. | ||
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| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Bioactive molecules |v 2 | |
| 500 | |a Literaturangaben | ||
| 650 | 4 | |a Carcinogens | |
| 650 | 4 | |a Neoplasms |x etiology | |
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Record in the Search Index
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|---|---|
| adam_text | NATURALLY OCCURRING
CARCINOGENS
OF PLANT ORIGIN
Toxicology, Pathology and Biochemistry
Edited by
Iwao HIRONO, Professor
Fujita-Gakuen Health University School of Medicine
Toyoake Aichi 4 70-11 Japan
Kodansha Elsevier
Tokyo Amsterdam—Oxford—New York—Tokyo
Contents
List of Contributors v
Preface vii
Introduction (I Hirono) 1
1 Cycasin (I Hirono) 3
1 1 Distribution of Cycads 3
1 2 Cycad as food 5
1 3 Discovery of the carcinogenicity of cycasin 7
1 4 Metabolism of cycasin and its carirogenicity 8
1 5 Biologic effects of cycasin and methylazoxymethanol (MAM) 15
1 6 Biochemical actions of cycasin and MAM 18
2 Pyrrolizidine Alkaloids
(T Furuya, Y Asada, H Mori) 25
2 1 Distribution and chemical structure of pyrrolizidine alkaloids 25
2 2 New macrocyclic pyrrolizidine alkaloids from Japanese com-
positae plants 31
2 3 Hepatotoxicity of pyrrolizidine alkaloids 36
2 4 Carcinogenicity of pyrrolizidine alkaloids 40
2 5 Genotoxicity of pyrrolizidine alkaloids 45
3 Flavonoids (S Natori, I Ueno) 53
3 1 Chemistry and distribution in plants 53
3 2 Mutagenicity 56
3 3 Carcinogenicity 61
3 4 Anti-inflammatory and other biological effects 63
4 Bracken Fern (I Hirono, K Yamada) 87
4 1 Toxicity of bracken 87
4 2 Carcinogenic properties of bracken 90
4 3 Carcinogenicity of bracken fern in laboratory animals other
than rats and livestock 93
ix
x CONTENTS
4 4 Embryotoxic effects of bracken fern 96
4 5 Various effects on carcinogenic activity of bracken 97
4 6 Epidemiology of the carcinogenicity of bracken fern 97
4 7 Difficulty of isolating bracken fern carcinogen 99
4 8 Isolation of bracken carcinogen 103
4 9 Structure and properties of ptaquiloside 106
4 10 Carcinogenicity test of ptaquiloside 111
4 11 Reproduction of acute bracken poisoning with PT 133
5 Carrageenan (I Hirono) 121
5 1 Chemical and physical properties of carrageenan 121
5 2 Toxic effect of carrageenan 122
5 3 Carcinogenicity of carrageenan 123
5 4 Carcinogenicity of dextran sulfate sodium 124
6 Mushroom Hydrazines (S Natori) 127
6 1 Occurrence and biochemistry of mushroom hydrazines 127
6 2 Carcinogenicity of mushroom hydrazines 131
7 Safrole (M Enomoto) 139
7 1 Chemical properties, natural occurence and use of safrole:
1 -allyl-3,4,-methylenedioxybenzene 139
7 2 Toxicity of safrole and related compounds 141
7 3 Carcinogenicity 146
7 4 Metabolism of safrole and some related compounds 152
7 5 Mutagenicity of safrole and related compounds 156
7 6 Conclusion 156
8 Tannins (Tannic acids) (M Enomoto) 161
8 1 Occurrence, chemistry and use 161
8 2 Toxicology and carcinogenicity 163
8 3 Conclusion 165
9 Betel Nut (H Mori) 167
9 1 History of betel chewing 167
9 2 Type, method and composition of the quid 167
9 3 Clinical and epidemiological evidence of betel chewing 169
9 4 Experimental evidence on betel quid 172
9 5 Genotoxicity and possible carcinogens of the betel nut and betel
quid ingredients 174
Contents xi
10 The Active Principles of the Euphobiaceae and
Thymelaeaceae (Y Hirata) 181
10 1 The principal parent diterpene skeletons 185
10 2 Irritation and tumor promotion 199
11 Noncarcinogenic plants and plant materials of Japan
(M Haga) 207
12 Plant Secondary Metabolites as Chemical Carcinogens
(S Natori) 217
12 1 Biosynthesis and functions of plant secondary metabolites 217
12 2 Naturally occurring carcinogens as secondary metabolites 219
12 3 Chemical structures of naturally occurring carcinogens 220
12 4 Role of metabolism and chemical characteristics of ultimate
carcinogens 224
12 5 Effects of naturally occurring carcinogens on human
health 226
Index 229
|
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| dewey-search | 616.99/4071 |
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| dewey-tens | 610 - Medicine and health |
| discipline | Chemie / Pharmazie Medizin |
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| id | DE-604.BV006123223 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T16:40:38Z |
| institution | BVB |
| isbn | 0444989722 4062021935 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-003868532 |
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| physical | XI, 234 S. Ill., graph. Darst. |
| publishDate | 1987 |
| publishDateSearch | 1987 |
| publishDateSort | 1987 |
| publisher | Kodansha [u.a.] |
| record_format | marc |
| series | Bioactive molecules |
| series2 | Bioactive molecules |
| spelling | Naturally occurring carcinogens of plant origin toxicology, pathology and biochemistry ed. by Iwao Hirono Tokyo Kodansha [u.a.] 1987 XI, 234 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Bioactive molecules 2 Literaturangaben Carcinogens Neoplasms etiology Plants, Toxic Poisonous plants Toxicology Pyrrolidinderivate (DE-588)4176525-4 gnd rswk-swf Pyrrolizidinalkaloide (DE-588)4369901-7 gnd rswk-swf Greiskraut Gattung (DE-588)4158134-9 gnd rswk-swf Giftpflanzen (DE-588)4021014-5 gnd rswk-swf Cycasin (DE-588)4350658-6 gnd rswk-swf Pflanzeninhaltsstoff (DE-588)4139067-2 gnd rswk-swf Carcinogen (DE-588)4032909-4 gnd rswk-swf Cycasin (DE-588)4350658-6 s DE-604 Greiskraut Gattung (DE-588)4158134-9 s Pyrrolizidinalkaloide (DE-588)4369901-7 s Carcinogen (DE-588)4032909-4 s Pflanzeninhaltsstoff (DE-588)4139067-2 s Pyrrolidinderivate (DE-588)4176525-4 s Giftpflanzen (DE-588)4021014-5 s Hirono, Iwao Sonstige oth Bioactive molecules 2 (DE-604)BV000022222 2 HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=003868532&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Naturally occurring carcinogens of plant origin toxicology, pathology and biochemistry Bioactive molecules Carcinogens Neoplasms etiology Plants, Toxic Poisonous plants Toxicology Pyrrolidinderivate (DE-588)4176525-4 gnd Pyrrolizidinalkaloide (DE-588)4369901-7 gnd Greiskraut Gattung (DE-588)4158134-9 gnd Giftpflanzen (DE-588)4021014-5 gnd Cycasin (DE-588)4350658-6 gnd Pflanzeninhaltsstoff (DE-588)4139067-2 gnd Carcinogen (DE-588)4032909-4 gnd |
| subject_GND | (DE-588)4176525-4 (DE-588)4369901-7 (DE-588)4158134-9 (DE-588)4021014-5 (DE-588)4350658-6 (DE-588)4139067-2 (DE-588)4032909-4 |
| title | Naturally occurring carcinogens of plant origin toxicology, pathology and biochemistry |
| title_auth | Naturally occurring carcinogens of plant origin toxicology, pathology and biochemistry |
| title_exact_search | Naturally occurring carcinogens of plant origin toxicology, pathology and biochemistry |
| title_full | Naturally occurring carcinogens of plant origin toxicology, pathology and biochemistry ed. by Iwao Hirono |
| title_fullStr | Naturally occurring carcinogens of plant origin toxicology, pathology and biochemistry ed. by Iwao Hirono |
| title_full_unstemmed | Naturally occurring carcinogens of plant origin toxicology, pathology and biochemistry ed. by Iwao Hirono |
| title_short | Naturally occurring carcinogens of plant origin |
| title_sort | naturally occurring carcinogens of plant origin toxicology pathology and biochemistry |
| title_sub | toxicology, pathology and biochemistry |
| topic | Carcinogens Neoplasms etiology Plants, Toxic Poisonous plants Toxicology Pyrrolidinderivate (DE-588)4176525-4 gnd Pyrrolizidinalkaloide (DE-588)4369901-7 gnd Greiskraut Gattung (DE-588)4158134-9 gnd Giftpflanzen (DE-588)4021014-5 gnd Cycasin (DE-588)4350658-6 gnd Pflanzeninhaltsstoff (DE-588)4139067-2 gnd Carcinogen (DE-588)4032909-4 gnd |
| topic_facet | Carcinogens Neoplasms etiology Plants, Toxic Poisonous plants Toxicology Pyrrolidinderivate Pyrrolizidinalkaloide Greiskraut Gattung Giftpflanzen Cycasin Pflanzeninhaltsstoff Carcinogen |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=003868532&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV000022222 |
| work_keys_str_mv | AT hironoiwao naturallyoccurringcarcinogensofplantorigintoxicologypathologyandbiochemistry |