Biology of the uterus:
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
New York [u.a.]
Plenum Medical Book Co.
1989
|
| Edition: | 2. ed. |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | Literaturangaben |
| Physical Description: | XVII, 625 S. zahlr. Ill., graph. Darst. |
| ISBN: | 0306430576 |
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MARC
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| 245 | 1 | 0 | |a Biology of the uterus |c ed. by Ralph M. Wynn ... |
| 250 | |a 2. ed. | ||
| 264 | 1 | |a New York [u.a.] |b Plenum Medical Book Co. |c 1989 | |
| 300 | |a XVII, 625 S. |b zahlr. Ill., graph. Darst. | ||
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| 500 | |a Literaturangaben | ||
| 650 | 4 | |a Utérus | |
| 650 | 4 | |a Uterus | |
| 650 | 4 | |a Uterus |x anatomy & histology | |
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Record in the Search Index
| _version_ | 1804118494358274048 |
|---|---|
| adam_text | BIOLOGY OF THE UTERUS
Second Edition
Edited by
RALPH M WYNN, M D
Professor, Departments of Obstetrics amp; Gynecology
and Anatomy amp; Cell Biology
Wayne State University School of Medicine
Detroit, Michigan
and
WILLIAM P JOLLIE, Ph D
Professor and Chairman, Department of Anatomy
Medical College of Virginia
Virginia Commonwealth University
Richmond, Virginia
PLENUM MEDICAL BOOK COMPANY
NEW YORK AND LONDON
Contents
1 History 1
ELIZABETH M RAMSEY
1 Greece 1
2 Alexandria 2
3 Rome 4
4 The Dark Ages 4
5 Renaissance 6
6 Seventeenth to Early Twentieth Centuries 8
7 Contemporary 13
8 References 17
2 Comparative Anatomy 19
HARLAND W MOSSMAN
1 Types of Uteri 22
2 Distribution and Probable Evolution of Uterine Types 23
3 Correlations of Uterine Types with Other Biological
Features 27
4 Miscellaneous Aspects of the Comparative Morphology
of the Uterus 29
5 Summary and Conclusions 32
6 References 32
7 Bibliography 34
3 Prenatal Human Development 35
RON AN O RAHILLY
1 Urinary Preliminaries 35
ix
CONTENTS
x 2 The Paramesonephric Ducts 37
3 The Vaginal Controversy 44
4 The Fetal Uterus 49
5 The Second Half of Prenatal Life 50
6 References 53
4 Vascular Anatomy 57
ELIZABETH M RAMSEY
1 Basic Aspects of Architecture and Physiology of Uterine Arteries 58
1 1 Nonpregnant 58
1 2 Pregnant 58
2 Interaction of Trophoblast and Decidua 62
3 Contemporary Studies 65
4 References 66
5 Vascular Physiology of the Nonpregnant
Uterus 69
FRANK C GREISS, JR , AND JAMES C ROSE
1 Fundamental Characteristics of the Uterine Vasculature 70
1 1 The Pressure—Flow Relationship 70
1 2 Autonomic Influences 70
1 3 Effects of Myometrial Contractions 73
1 4 Endocrine Regulation 74
2 Uterine Blood Flow during the Ovarian Cycle 77
2 1 Temporal Changes 77
2 2 Hormonal and Other Correlates 78
3 Mediators of Estrogen-Induced Vasodilatation 79
4 Responses of the Nonplacental Uterine Vasculature during
Pregnancy 81
5 Conclusion 84
6 References 84
6 Cellular Biochemistry of the Endometrium 89
JOHN D APLIN
1 Methodological Comments 90
2 Intracellular Constituents 91
2 1 Cytoskeletal Proteins 91
2 2 Oncogene Products 95
2 3 The 24k Protein 96
3 Cell Surface 96
3 1 Cell Polarity 97
CONTENTS
3 2 Cell Location 97 xi
3 3 Hormone-Dependent Alterations 98
3 4 Preparation for Implantation 100
4 Extracellular Matrix 100
4 1 Interstitial Components 100
4 2 Basal Laminal Components 106
4 3 Functional Significance of Matrix Reorganization 108
5 Secretory Components 109
5 1 Uteroglobin 109
5 2 Iron-Binding Secretory Products 110
5 3 Prolactin Ill
5 4 Diamine Oxidase Ill
5 5 a2-PEG 112
5 6 arPEG 113
5 7 High-Molecular-Weight Components 114
5 8 Other Glycoproteins 117
6 Concluding Remarks 118
7 References 119
7 Cell Biology of the Endometrium 131
WENDELL W LEAVITT
1 Mechanism of Hormone Action 134
1 1 General Mechanism of Hormone Action 134
1 2 Polypeptide Hormones 134
1 3 Steroid Hormones 135
1 4 Estrogen Marker Proteins 137
1 5 Progesterone Marker Proteins 137
2 Steroid Receptors 146
2 1 Receptor Distribution 146
2 2 Receptor Assays 147
2 3 Nuclear Acceptor Sites 149
2 4 Estrogen—Progestin Interactions 150
2 5 Hamster Estrous-Cycle 152
2 6 Pregnancy 154
2 7 Density-Shift Studies 154
28A Unifying Concept 159
3 References • 162
8 The Endometrium of Delayed and Early
Implantation 175
RANDALL L GIVEN AND ALLEN C ENDERS
Marsupials
Roe Deer
xii 3 Armadillos 182
4 Insectivores and Chiroptera 186 CONTENTS „ R , OC t Carnivores lob
5 1 Seals 187
5 2 Bears 188
5 3 Mustelids 188
6 Rodents 203
7 Nonhuman Primates 212
8 Discussion 219
9 References 223
9 The Implantation Reaction 233
MARGARET B PARR AND EARL L PARR
1 Adhesion 233
1 1 Morphological Changes in the Uterine Epithelial Cell
Surface 234
1 2 Surface Charge on Blastocysts 234
1 3 Surface Charge on the Uterine Epithelium 236
1 4 Cell Adhesion Mechanisms 237
1 5 Surface Glycoproteins on Blastocysts 237
1 6 Surface Glycoproteins on Uterine Epithelial Cells 239
2 Vascular Permeability 241
2 1 Blood Vessels Responsible for Increased Vascular
Permeability 241
2 2 Role of Prostaglandins in Increased Vascular
Permeability 244
2 3 Endometrial Prostaglandins 245
2 4 Blastocyst Prostaglandins 246
3 The Decidual Cell Reaction 247
3 1 The Primary Decidual Zone 248
3 2 Antimesometrial Decidua 251
3 3 Mesometrial Decidua 255
3 4 The Role of Prostaglandins in Initiating Decidualization 256
3 5 Mechanisms of Prostaglandin Effects on Vascular
Permeability and Decidualization 257
3 6 Decidual Cell Metabolism 258
3 7 Functions of Decidual Tissue 260
4 Epithelial Cell Loss 260
4 1 The Uterine Epithelium Adjacent to the
Trophoblast 260
4 2 Apoptosis as the Mode of Cell Death in Uterine
Epithelium 261
4 3 Effects of Trophoblast on Uterine Epithelium 263
4 4 Effects of Decidual Tissue on Uterine Epithelium 266
5 References 267
10 Regeneration in the Primate Uterus: The xiii
Role of Stem Cells 279 CONTENTS
HELEN A PADYKULA
1 Endometriectomy and the Location of the Endometrial
Stem Cells 280
2 Compartmentalization of the Primate Endometrium 282
3 Zonation of the Primate Endometrium 283
4 Cyclic Changes in Endometrial Zonal Uptake of [3H]Thymidine 285
4 1 Epithelial Mitotic Activity in the Transient Compartment
during Estrogen Dominance 285
4 2 Germinal Mechanisms in the Endometrial Basalis 285
5 Hypothesis: Cyclic Endometrial Renewal in Menstruating
Primates 287
6 References 287
11 The Human Endometrium: Cyclic and
Gestational Changes 289
RALPH M WYNN
1 Histology 289
2 Ultrastructure 294
2 1 The Normal Menstrual Cycle 294
2 2 The Nucleolar Channel System 302
2 3 The Decidua 304
2 4 The Arias-Stella Reaction 310
2 5 Scanning Electron Microscopy 311
2 6 Ultrastructural Localization of Enzymes 314
3 Clinical Correlations 317
3 1 Effects of Contraceptive Agents 317
3 2 Menstruation 319
4 Structural Vascular Changes in Normal and Hypertensive
Pregnancies 320
5 References 329
12 Endometrial Hyperplasia and Neoplasia 333
ALEX FERENCZY AND CHRISTINE BERGERON
1 Laboratory Evidence 334
1 1 Histology 334
1 2 Electron Microscopy 335
1 3 Morphometry, DNA-Feulgen Microspectrophotometry,
and Flow Cytometry 337
xiv 1 4 In Vitro DNA Histoautoradiography
1 5 Immunohistochemistry CONTENTS __,2 Clinical Evidence
3 Coexistent Association
4 Clinical Implications of the Two-Disease Concept
5 References
13 Biochemistry of the Myometrium and
Cervix
GABOR HUSZAR AND MICHAEL P WALSH
1 The Structure of the Myometrium
1 1 Cellular Organization
1 2 Filament Structure and Function
2 Calcium and Contractile Regulation
2 1 The Importance of Ca2+ Ions
2 2 The Source of Activating Calcium
2 3 Measurements of Cellular Ca2+ Transients
3 Regulation of Transmembrane Ca2+ Fluxes
3 1 Mechanisms of Ca2+ Efflux
3 2 The Ca2+ Transport System of the Sarcoplasmic
Reticulum
3 3 Mechanisms of Ca2+ Influx
4 Contractile Proteins of the Myometrium
4 1 Myosin
4 2 Thin Filament Proteins
5 Regulation of Myometrial Contractility
5 1 Calmodulin
5 2 Calmodulin-Dependent Myosin Light Chain Kinase
5 3 The Mechanism of MLCK Action
5 4 Modulation of Smooth Muscle Contractility
— by MLCK
5 5 Myosin Light Chain Phosphatase
5 6 Phosphorylation of Myosin Light Chain and Heavy Chains
by Other Kinases
5 7 Second-Site Phosphorylation of Myosin
6 Mechanisms of Smooth Muscle Regulation Other Than MLCK
6 1 Thin Filament Regulation: Caldesmon
6 2 Regulation of Smooth Muscle Contraction by Cyclic
Nucleotides
6 3 Endocrine Regulation of Myometrial Contractility
7 Integrated Model for Regulation of Smooth Muscle Contractility
8 Preterm Birth and Tocolytic Therapy
8 1 Calcium Channel-Blocking Agents
8 2 Prostaglandin Synthesis Inhibitors
8 3 Calmodulin-Inhibiting Drugs
8 4 Functional Peptides
8 5 The Efficacy of p-Adrenergic Agents :
385,
9 Cervix 385 xv
9 1 Biochemistry of Cervical Maturation 385
9 2 Hormonal Control of Cervical Maturation 387 CONTENTS
9 3 Relationship between Myometrial Contractility and
Cervical Maturation 388
10 References 390
14 Electrophysiological Properties of Uterine
Smooth Muscle 403
c Y KAO
1 Review of Methodology 404
1 1 Comparison of Uterine, Cardiac, and Skeletal
Muscles 404
12A Brief Statement of the Ionic Theory
of Excitation 405
1 3 Methods of Studying Electrical Activities of Smooth
Muscles 409
2 Ionic Distribution as the Basis of Electrophysiological
Phenomena 418
2 1 Studies in Ionic Contents and Distribution 418
2 2 Ionic Contents and Intracellular Concentrations 419
2 3 Hormonal and Gestational Influences on Ionic
Distribution 423
3 Electrical Activity of the Myometrium and Other Mammalian
Smooth Muscles 424
3 1 Descriptive Phenomena 424
3 2 Ionic Basis of Electrical Activity 428
3 3 Tissue Phenomena 442
3 4 Actions of Some Drugs on the Myometrium 445
4 Summary and Concluding Remarks 449
5 References 450
15 Ultrastructure of the Myometrium 455 «v
W C COLE AND R E GARFIELD
1 Cellular Organization of the Myometrium 455
2 Ultrastructure of Myometrial Smooth Muscle Cells 458 _
2 1 Size and Shape 458
2 2 Organelles : 459
2 3t The Plasma Membrane 464
2 4 Effects of Hormones and Pregnancy 468
3 Gap Junctions and Cell-to-Cell Communication in the
Myometrium 469
3 1 Gap Junction Structure 469
3 2 Gap Junctions in the Myometrium 471
xvi 3 3 Function of Gap Junctions 473
3 4 Control of Myometrial Junctional Communication 480
CONTENTS g - Significance of Gap Junctions and Their Modulation
to Pregnancy and Parturition 487
4 Contractile Mechanism of Myometrial Smooth
Muscle Cells 488
4 1 Thin Filaments 488
4 2 Thick Filaments 491
4 3 Cytoplasmic and Membrane-Associated Dense
Bodies 493
4 4 Intermediate Filaments 494
4 5 Structural Organization of the Contractile Apparatus and
Its Possible Association with the Cytoskeleton 495
4 6 Mechanical Transmission in a Multicellular Tissue 497
5 Conclusion 497
6 References 498
16 Uterine Control of Ovarian Function 505
L L ANDERSON AND A I MUSAH
1 Ovarian Function 505
1 1 Corpus Luteum in Rodentia and Lagomorpha 506
1 2 Corpus Luteum in Artiodactyla 508
1 3 Corpus Luteum in Primates 512
2 Uterine Function 512
2 1 Development and Regression of Endometrium and
Myometrium 512
2 2 Role of the Uterus in Cyclic Periodicity 514
3 Uterine—Ovarian and Conceptus Interaction in Regulation of
Ovarian Function 517
3 1 Uterine-Ovarian Function during Pregnancy 517
3 2 The Role of Uterine-Conceptus Interactions on Ovarian
Function 522
3 3 Uterine—Ovarian Microcirculation and Ovarian Function 524
4 Luteolytic Actions of the Uterus: Effects of Hysterectomy on
Ovarian Function 526
4 1 The Uterus and Luteal Function in Rodentia and
Lagomorpha 527
4 2 The Uterus and Luteal Function in Artiodactyla 528
4 3 The Uterus and Luteal Function in Primates - 530
5 Uterine—Ovarian Hormones and Ovarian Function 532
5 1 Prostanoids and Leukotrienes 532
5 2 Relaxin 534
5 3 Oxytocin 536
5 4 Other Hormones Affecting Uterine Function:
ACTH 538
6 Mechanisms of Uterine-Ovarian Interactions in Regulating
Ovarian Function 538
6 1 Morphology and Function of Placental and Luteal
Cells
6 2 Cellular and Biochemical Basis of Uterine-Ovarian
Interactions
7 References
17 Endocrine Control of Parturition 559
MELVYN S SOLOFF
1 Problems in Understanding Basic Mechanisms
of Parturition 559
2 Preparation of the Uterus for Labor: Estrogen 560
2 1 Possible Regulation of Estrogen Action at the Receptor
Level 562
2 2 The Role of Estrogens in Humans 562
2 3 Identification of Active Estrogens in Humans 562
2 4 Control of Estrogen Levels 563
3 Uterine Quiescence 564
3 1 Progesterone 564
3 2 Relaxin 566
3 3 Adrenergic Agents 568
4 Activators of Uterine Activity 569
4 1 Prostaglandins 569
4 2 Oxytocin 580
4 3 Relaxin 590
5 Cervical Distensibility 590
5 1 Hormonal Control of Cervical Maturation 591 i
5 2 Relationship between Cervical Maturation and Myometrial j
Contractions 592
6 A General Model for Parturition 593
7 Unification of Mechanisms Proposed for Spontaneous Labor
Induction 593
7 1 Prostaglandins 593
7 2 Estrogen/Progesterone 594
7 3 Fetal ACTH 594
8 References 594
Index 609
XVLL
538 CONTENTS
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| id | DE-604.BV004303769 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T16:11:11Z |
| institution | BVB |
| isbn | 0306430576 |
| language | English |
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| physical | XVII, 625 S. zahlr. Ill., graph. Darst. |
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| spelling | Biology of the uterus ed. by Ralph M. Wynn ... 2. ed. New York [u.a.] Plenum Medical Book Co. 1989 XVII, 625 S. zahlr. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Literaturangaben Utérus Uterus Uterus anatomy & histology Uterus physiology Gebärmutter (DE-588)4019493-0 gnd rswk-swf Biologie (DE-588)4006851-1 gnd rswk-swf Gebärmutter (DE-588)4019493-0 s Biologie (DE-588)4006851-1 s DE-604 Wynn, Ralph M. Sonstige oth HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=002676486&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Biology of the uterus Utérus Uterus Uterus anatomy & histology Uterus physiology Gebärmutter (DE-588)4019493-0 gnd Biologie (DE-588)4006851-1 gnd |
| subject_GND | (DE-588)4019493-0 (DE-588)4006851-1 |
| title | Biology of the uterus |
| title_auth | Biology of the uterus |
| title_exact_search | Biology of the uterus |
| title_full | Biology of the uterus ed. by Ralph M. Wynn ... |
| title_fullStr | Biology of the uterus ed. by Ralph M. Wynn ... |
| title_full_unstemmed | Biology of the uterus ed. by Ralph M. Wynn ... |
| title_short | Biology of the uterus |
| title_sort | biology of the uterus |
| topic | Utérus Uterus Uterus anatomy & histology Uterus physiology Gebärmutter (DE-588)4019493-0 gnd Biologie (DE-588)4006851-1 gnd |
| topic_facet | Utérus Uterus Uterus anatomy & histology Uterus physiology Gebärmutter Biologie |
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