Toxicokinetics and new drug development:
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
New York u.a.
Pergamon Pr.
1989
|
| Edition: | 1. ed. |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XII, 246 S. |
| ISBN: | 008036084X |
Staff View
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| 245 | 1 | 0 | |a Toxicokinetics and new drug development |c ed. by Avraham Yacobi ... |
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Record in the Search Index
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| adam_text | TOXICOKINETICS AND NEW DRUG DEVELOPMENT EDITED BY AVRAHAM YACOBI, PH.D.
AMERICAN CYANAMID COMPANY, LEDERLE LABORATORIES PEARL RIVER, NEW YORK
JEROME P. SKELLY, PH.D. THE FOOD AND DRUG ADMINISTRATION ROCKVILLE, MD
VIJAY K. BATRA, PH.D. AMERICAN CYANAMID COMPANY, LEDERLE LABORATORIES
PEARL RIVER, NEW YORK COSPONSORED BY THE AMERICAN ASSOCIATION OF
PHARMACEUTICAL SCIENTISTS PERGAMON PRESS NEW YORK * OXFORD * BEIJING *
FRANKFURT SAO PAULO * SYDNEY * TOKYO * TORONTO CONTENTS CONTRIBUTORS VII
PREFACE XI 1. AN OVERVIEW OF TOXICOKINETICS 1 VIJAY K. BATRA AND AVRAHAM
YACOBI 2. ROLE OF TOXICOKINETICS IN DRUG SAFETY EVALUATIONS 21 FELIX A.
DE LA IGLESIA AND PETER GREAVES 3. TOXICOKINETICS IN PRECLINICAL
EVALUATION OF DRUG SAFETY 33 V. C. GLOCKLIN AND C. C. CHAH 4. THE USE OF
INTERSPECIES SCALING IN TOXICOKINETICS 42 JOYCE MORDENTI AND WILLARD
CHAPPELL 5. SOME PHARMACODYNAMIC ASPECTS OF TOXICOKINETICS 97 GERHARD
LEVY 6. ROLE OF PHARMACOKINETICS IN DRUG EVALUATION: SAFETY-RELATED
ISSUES 108 ROBERT TEMPLE 7. PHARMACOKINETICS AND ADVERSE REACTIONS: AN
OVERVIEW 114 LOUIS LEMBERGER 8. CLINICAL PHARMACODYNAMICS OF ANTICANCER
DRUGS: CONCEPTS AND EXAMPLES 124 WILLIAM E. EVANS AND JOHN H. RODMAN 9.
THE ROLE OF ACTIVE METABOLITES IN DRUG RESPONSIVENESS AND TOXICITY:
ENCAINIDE AND PROPAFENONE 136 GRANT R. WILKINSON 10. NITROGEN OXIDATION
AND TOXICITY 149 ARTHUR K. CHO, JOHN F. BRADY, AND JUDITH N. BURSTYN VI
CONTENTS 11. COMPREHENSIVE EVALUATION OF THE CENTRAL NERVOUS SYSTEM
EFFECTS OF CIMETIDINE: A ROLE FOR TOXICOKINETICS, TOXICODYNAMICS, AND
CLINICAL STUDIES IN VOLUNTEERS, ANIMAL MODELS, AND PATIENTS 160 JEROME
J. SCHENTAG, PATRICIA L. EBBELING, JOHN A. ZIEMNIAK, LYNDA L. WELAGE,
AND HAROLD BERNHARD 12. GASTROINTESTINAL TOXICITY: DISPOSITIONAL
CONSIDERATIONS 199 K. ROZMAN AND M. J. IATROPOULOS 13. RENAL TOXICITY:
STRUCTURAL, FUNCTIONAL, KINETIC, AND DYNAMIC CONSIDERATIONS 214 M. J.
IATROPOULOS 14. SELECTION AND EVALUATION OF DRUG DELIVERY SYSTEMS FOR
TOXICOLOGY STUDIES*TRANSDERMAL DOSAGE FORMS 227 VIJAY K. BATRA, GABRIELA
NICOLAU, A. TONELLI, JOHN A. MORRISON, AND AVRAHAM YACOBI INDEX 241
|
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| indexdate | 2024-07-09T16:08:54Z |
| institution | BVB |
| isbn | 008036084X |
| language | English |
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| physical | XII, 246 S. |
| publishDate | 1989 |
| publishDateSearch | 1989 |
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| publisher | Pergamon Pr. |
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| spelling | Toxicokinetics and new drug development ed. by Avraham Yacobi ... 1. ed. New York u.a. Pergamon Pr. 1989 XII, 246 S. txt rdacontent n rdamedia nc rdacarrier Médicaments - Essais cliniques Médicaments - Toxicologie Pharmacocinétique Drug Evaluation Drug Toxicity Drug development Drugs Toxicology Pharmacokinetics Toxizitätstest (DE-588)4060540-1 gnd rswk-swf Pharmakokinetik (DE-588)4115557-9 gnd rswk-swf Arzneimittel (DE-588)4003115-9 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Arzneimittel (DE-588)4003115-9 s Toxizitätstest (DE-588)4060540-1 s Pharmakokinetik (DE-588)4115557-9 s DE-604 Yacobi, Avraham Sonstige oth GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=002579922&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Toxicokinetics and new drug development Médicaments - Essais cliniques Médicaments - Toxicologie Pharmacocinétique Drug Evaluation Drug Toxicity Drug development Drugs Toxicology Pharmacokinetics Toxizitätstest (DE-588)4060540-1 gnd Pharmakokinetik (DE-588)4115557-9 gnd Arzneimittel (DE-588)4003115-9 gnd |
| subject_GND | (DE-588)4060540-1 (DE-588)4115557-9 (DE-588)4003115-9 (DE-588)4143413-4 |
| title | Toxicokinetics and new drug development |
| title_auth | Toxicokinetics and new drug development |
| title_exact_search | Toxicokinetics and new drug development |
| title_full | Toxicokinetics and new drug development ed. by Avraham Yacobi ... |
| title_fullStr | Toxicokinetics and new drug development ed. by Avraham Yacobi ... |
| title_full_unstemmed | Toxicokinetics and new drug development ed. by Avraham Yacobi ... |
| title_short | Toxicokinetics and new drug development |
| title_sort | toxicokinetics and new drug development |
| topic | Médicaments - Essais cliniques Médicaments - Toxicologie Pharmacocinétique Drug Evaluation Drug Toxicity Drug development Drugs Toxicology Pharmacokinetics Toxizitätstest (DE-588)4060540-1 gnd Pharmakokinetik (DE-588)4115557-9 gnd Arzneimittel (DE-588)4003115-9 gnd |
| topic_facet | Médicaments - Essais cliniques Médicaments - Toxicologie Pharmacocinétique Drug Evaluation Drug Toxicity Drug development Drugs Toxicology Pharmacokinetics Toxizitätstest Pharmakokinetik Arzneimittel Aufsatzsammlung |
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