Modern pharmaceutics:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York u.a.
Dekker
1990
|
| Ausgabe: | 2. ed., rev. and expanded |
| Schriftenreihe: | Drugs and the pharmaceutical sciences
40 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIV, 888 S. Ill. |
| ISBN: | 082477499X |
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| 650 | 4 | |a Pharmacocinétique | |
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Datensatz im Suchindex
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| adam_text | MODERN PHARMACEUTICS SECOND EDITION, REVISED AND EXPANDED EDITED BY
GILBERT S. BANKER UNIVERSITY OF MINNESOTA MINNEAPOLIS, MINNESOTA
CHRISTOPHER T. RHODES *: * UNIVERSITY OF RHODE ISLAND * KINGSTON,
RHODE ISLAND MARCEL DEKKER, INC. NEW YORK AND BASEL CONTENTS PREFACE
CONTRIBUTORS ILL V CHAPTER 1. DRUG PRODUCTS: THEIR ROLE IN THE TREATMENT
OF DISEASE, THEIR QUALITY, AND THEIR CURRENT AND FUTURE STATUS AS DRUG
DELIVERY SYSTEMS 1 GILBERT S. BANKER I. ROLE OF DRUGS AND DRUG PRODUCTS
IN THE TREATMENT AND PREVENTION OF DISEASE 1 II. DRUG AND DRUG PRODUCT
QUALITY AND ITS EVALUATION 6 III. THE DRUG PRODUCT AS A DELIVERY SYSTEM
15 REFERENCES 21 CHAPTER 2. PRINCIPLES OF DRUG ABSORPTION 23 MICHAEL
MAYERSOHN I. INTRODUCTION 23 II. ANATOMICAL AND PHYSIOLOGICAL
CONSIDERATIONS OF THE GASTROINTESTINAL TRACT 24 III. PHYSICOCHEMICAL
FACTORS GOVERNING DRUG ABSORPTION 30 IV. PHYSIOLOGICAL FACTORS GOVERNING
DRUG ABSORPTION 47 V. COMPLICATING FACTORS IN DRUG ABSORPTION 62
REFERENCES 72 X CHAPTER 3. CHAPTER 4. CHAPTER 5. CHAPTER 6.
PHARMACOKINETICS DAVID W. A. BOURNE AND LEWIS VI. DITTERT CONTENTS 91 I.
INTRODUCTION 91 II. PRINCIPLES OF FIRST-ORDER KINETICS 92 III.
FIRST-ORDER PHARMACOKINETICS: DRUG ELIMINATION FOLLOWING RAPID
INTRAVENOUS INJECTION 100 IV. PHARMACOKINETIC ANALYSIS OF URINE DATA 103
V. CLEARANCE RATE AS AN EXPRESSION OF DRUG ELIMINATION RATE 106 VI.
PHARMACOKINETICS OF DRUGS ELIMINATED BY SIMULTANEOUS METABOLISM AND
EXCRETION 108 VII. KINETICS OF DRUG ABSORPTION 115 VIII. BIOAVAILABILITY
(EXTENT OF ABSORPTION) 124 IX. MULTIPLE-DOSING REGIMENS (REPETITIVE
DOSING) 129 REFERENCES 142 FACTORS INFLUENCING DRUG ABSORPTION AND DRUG
AVAILABILITY 143 BETTY-ANN HOENER AND LESLIE Z. BENET I. INTRODUCTION
143 II. GETTING THE DRUG TO ITS SITE OF ABSORPTION 144 III. GETTING THE
DRUG INTO SOLUTION: FACTORS AFFECTING THE RATE OF DISSOLUTION 152 IV.
GASTROINTESTINAL MEMBRANE TRANSPORT 174 V. MOVING THE DRUG AWAY FROM THE
SITE OF ABSORPTION 174 VI. SUMMARY 177 REFERENCES 177 THE EFFECT OF
ROUTE OF ADMINISTRATION AND DISTRIBUTION ON DRUG ACTION 181 LESLIE Z.
BENET I. DOSE-EFFICACY SCHEME 181 II. PHYSIOLOGICAL CONSIDERATIONS FOR
THE VARIOUS ROUTES AND PATHWAYS OF DRUG INPUT 183 III. DRUG DISTRIBUTION
195 IV. SUMMARY 204 REFERENCES 204 CHEMICAL KINETICS AND DRUG STABILITY
209 HO-LEUNG FUNG I. INTRODUCTION 209 II. MODES OF PHARMACEUTICAL
DEGRADATION 210 III. QUANTITATION OF RATE OF DEGRADATION 217 IV. THE
ARRHENIUS EQUATION AND ACCELERATED STABILITY TESTING 224 V.
ENVIRONMENTAL FACTORS THAT AFFECT REACTION RATE 226 REFERENCES 235
CONTENTS CHAPTER 7. CHAPTER 8. CHAPTER 9. CHAPTER 10. CHAPTER 11.
PREFORMULATION JENS T. CARSTENSEN I. INTRODUCTION II. TIMING AND GOALS
OF PREFORMULATION III. PHYSICOCHEMICAL PARAMETERS IV. COMPATIBILITY
TESTS V. DISSOLUTION OF DRUG SUBSTANCE AND DOSAGE FORM REFERENCES
TOPICAL DRUG ABSORPTION AND TOPICAL PHARMACEUTICAL SYSTEMS GORDON L.
FLYNN I. INTRODUCTION II. NATURE OF THE SKIN III. MECHANISTIC ANALYSIS
OF RELEVANT SKIN FUNCTIONS IV. RATIONALE FOR TOPICALS V. UNIQUE
PHYSICOCHEMICAL SYSTEMS USED TOPICALLY VI. PERFORMANCE CRITERIA AND
PERFORMANCE EVALUATION OF TOPICAL THERAPEUTIC SYSTEMS REFERENCES
DISPERSE SYSTEMS CHRISTOPHER T. RHODES I. INTRODUCTION II. SOME
FUNDAMENTAL PROPERTIES OF DISPERSE SYSTEMS III. SOLUBILIZED SYSTEMS IV.
SUSPENSIONS V. EMULSIONS REFERENCES TABLET DOSAGE FORMS KEITH MARSHALL
AND EDWARD M. RUDNIC I. INTRODUCTION II. DESIGN AND FORMULATION OF
COMPRESSED TABLETS III. COATED TABLETS IV. THE ROLE OF PROCESSING
CONDITIONS V. MOLDED TABLETS (TABLET TRITURATES) VI. EVALUATION OF
TABLETS REFERENCES SPECIALTY TABLETS AND CAPSULES RALPH F. SHANGRAW I.
INTRODUCTION II. BUCCAL AND TRANSMUCOSAL TABLETS III. SUBLINGUAL TABLETS
IV. STABILITY AND PACKAGING OF MOLDED NITROGLYCERIN TABLETS V. IMPLANTS
VI. EFFERVESCENT TABLETS XI 239 239 240 240 251 258 261 263 263 264 273
277 298 310 323 327 327 327 334 339 347 351 355 355 360 388 400 414 416
421 427 427 427 428 430 432 433 XII CONTENTS VII. VAGINAL TABLETS VIII.
LOZENGES IX. CHEWABLE TABLETS X. ANALYTICAL TABLETS REFERENCES CHAPTER
12. HARD AND SOFT GELATIN CAPSULES LARRY L. AUGSBURGER I. HISTORICAL
DEVELOPMENT AND ROLE AS A DOSAGE FORM II. HARD GELATIN CAPSULES III.
SOFT GELATIN CAPSULES IV. SOFT/LIQUID-FILLED HARD GELATIN CAPSULES
REFERENCES BIBLIOGRAPHY CHAPTER 13. PARENTERAL PRODUCTS JAMES C. BOYLAN
AND ALAN L. FITES I. INTRODUCTION II. ROUTES OF PARENTERAL
ADMINISTRATION III. SPECIALIZED LARGE-VOLUME PARENTERAL AND STERILE
SOLUTIONS IV. DESIGN OF PARENTERAL PRODUCTS AND METHODS OF PREPARATION
V. COMPONENTS OF PARENTERAL PRODUCTS AND PHYSICOCHEMICAL FACTORS
AFFECTING THEIR DESIGN AND PERFORMANCE VI. STERILIZATION METHODS VII.
CLINICAL CONSIDERATIONS IN PARENTERAL PRODUCT DESIGN VIII. QUALITY
CONTROL REFERENCES CHAPTER 14. DESIGN AND EVALUATION OF OPHTHALMIC
PHARMACEUTICAL PRODUCTS GERALD HECHT, ROBERT E. ROEHRS, EUGENE R.
COOPER, JOSEPH W. HIDDEMEN, AND BARRY F. VAN DUZEE I. INTRODUCTION II.
HISTORICAL BACKGROUND III. ANATOMY OF THE EYE AND ADNEXA IV.
PHARMACOLOGY AND THERAPEUTICS OF OPHTHALMIC MEDICATION V. GENERAL SAFETY
CONSIDERATIONS VI. ABSORPTION OF DRUGS IN THE EYE VII. MANUFACTURING
CONSIDERATIONS VIII. CLASSES OF OPHTHALMIC PRODUCTS IX. CONTACT LENS
CARE PRODUCTS REFERENCES 436 436 438 438 439 441 441 442 478 483 484 490
491 491 493 500 502 511 520 526 531 536 539 539 542 543 545 547 554 559
563 585 598 CONTENTS CHAPTER 15. PHARMACEUTICAL AEROSOLS JOHN J. SCIARRA
AND ANTHONY J. CUTIE I. INTRODUCTION II. DEFINITIONS III. ADVANTAGES OF
THE AEROSOL DOSAGE FORM IV. OPERATION OF THE AEROSOL PACKAGE V. PRODUCT
FORMULATION VI. PROPELLANTS VII. VALVES VIII. AEROSOL CONTAINERS IX.
ORAL, INHALATION, AND NASAL AEROSOLS X. TOPICAL AEROSOLS XI. FUTURE
DEVELOPMENTS BIBLIOGRAPHY CHAPTER 16. SUSTAINED- AND CONTROLLED-RELEASE
DRUG DELIVERY SYSTEMS GEORGE M. GRASS IV AND JOSEPH R. ROBINSON XIII 605
605 606 606 607 608 616 622 625 626 631 632 634 635 CHAPTER 17. I. II.
III. IV. V. VI. VII. VIII. IX. INTRODUCTION TERMINOLOGY ORAL SYSTEMS
TARGETED DELIVERY SYSTEMS TRANSDERMAL SYSTEMS OCULAR SYSTEMS
INTRAVAGINAL AND INTRAUTERINE SYSTEMS INJECTIONS AND IMPLANTS
CONCLUSIONS REFERENCES SITE-SPECIFIC DRUG DELIVERY USING PARTICULATE
SYSTEMS ERIC TOMLINSON I. II. III. IV. V. INTRODUCTION SITE-SPECIFIC
DRUG DELIVERY PARTICULATE SYSTEMS FOR SITE-SPECIFIC DRUG DELIVERY AND
CONTROLLED RELEASE PROPERTIES OF PARTICULATE SITE-SPECIFIC DELIVERY
SYSTEMS USES REFERENCES 635 636 638 658 663 665 666 667 668 668 673 673
674 675 679 691 692 CHAPTER 18. PACKAGING OF PHARMACEUTICAL DOSAGE FORMS
695 DONALD C. LIEBE I. INTRODUCTION 695 II. PACKAGING OF SOLID ORAL
DOSAGE FORMS 699 III. PACKAGING OF PARENTERAL AND OPHTHALMIC DOSAGE
FORMS 717 IV. PACKAGING OF OTHER DOSAGE FORMS 730 V. SUMMARY AND
CONCLUSIONS 735 REFERENCES 736 XIV CONTENTS CHAPTER 19. APPRAISAL OF
DRUG PRODUCT QUALITY AND PERFORMANCE STANLEY L. HEM AND ROGER G. STOLL
741 CHAPTER 20. CHAPTER 21. I. II. III. IV. V. VI. VII. VIII. IX. X. XI.
XII. INTRODUCTION PURITY AND IDENTITY OF ACTIVE INGREDIENT CONTENT
UNIFORMITY CHEMICAL STABILITY PHYSICAL STABILITY B IOA VAILABILITY
INEQUIVALENT BIOEQUIVALENCE RELATIONSHIP BETWEEN IN VITRO TESTS AND
BIOEQUIVALENCE SUMMARY OF FACTORS INFLUENCING B IOA VAILABILITY DATA
QUALITY CONTROL MANUFACTURER S RELIABILITY MANUFACTURER/DRUG INFORMATION
PROFILE REFERENCES OPTIMIZATION TECHNIQUES IN PHARMACEUTICAL FORMULATION
AND PROCESSING JOSEPH I. II. III. IV. V. VI. VII. VIII. B. SCHWARTZ
INTRODUCTION OPTIMIZATION PARAMETERS CLASSICAL OPTIMIZATION STATISTICAL
DESIGN APPLIED OPTIMIZATION METHODS OTHER APPLICATIONS COMPUTERS AND
SYSTEMS CONCLUDING REMARKS REFERENCES FOOD AND DRUG LAWS THAT AFFECT
DRUG PRODUCT DESIGN, MANUFACTURE, AND DISTRIBUTION GARNET I. II. III. E.
PECK IMPACT OF THE FOOD AND DRUG LAWS LAWS GOVERNING EVALUATION OF NEW
DRUG PRODUCTS LAWS GOVERNING PREPARATION AND DISTRIBUTION 741 743 746
748 750 751 788 791 795 796 797 799 799 803 803 804 804 806 807 823 826
826 827 829 829 834 OF EXISTING PRODUCTS 841 IV. FURTHER CONSIDERATIONS
848 REFERENCES 849 CHAPTER 22. A VIEW TO THE FUTURE 851 GILBERT S.
BANKER AND CHRISTOPHER T. RHODES I. INTRODUCTION 851 II. THE
PHARMACEUTICAL INDUSTRY 852 III. COMMUNITY AND HOSPITAL PRACTICE 854 IV.
ADVANCES IN THE MONITORING OF PHARMACOTHERA- PEUTICS AND IN DRUG
DELIVERY SYSTEM DESIGN 856 V. CONCLUSION 869 REFERENCES 869 INDEX 871
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| id | DE-604.BV002545468 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T15:46:35Z |
| institution | BVB |
| isbn | 082477499X |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-001638436 |
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| owner_facet | DE-12 DE-355 DE-BY-UBR |
| physical | XIV, 888 S. Ill. |
| publishDate | 1990 |
| publishDateSearch | 1990 |
| publishDateSort | 1990 |
| publisher | Dekker |
| record_format | marc |
| series | Drugs and the pharmaceutical sciences |
| series2 | Drugs and the pharmaceutical sciences |
| spelling | Modern pharmaceutics ed. by Gilbert S. Banker 2. ed., rev. and expanded New York u.a. Dekker 1990 XIV, 888 S. Ill. txt rdacontent n rdamedia nc rdacarrier Drugs and the pharmaceutical sciences 40 Biopharmacie Geneesmiddelen gtt Industrie pharmaceutique - Qualité - Contrôle Médicaments - Formes pharmaceutiques Pharmacocinétique Biopharmaceutics Drugs Dosage forms Pharmaceutical industry Quality control Pharmacokinetics Arzneimittel (DE-588)4003115-9 gnd rswk-swf Arzneiform (DE-588)4068874-4 gnd rswk-swf Qualitätskontrolle (DE-588)4047968-7 gnd rswk-swf Pharmazie (DE-588)4045705-9 gnd rswk-swf Pharmazie (DE-588)4045705-9 s DE-604 Arzneimittel (DE-588)4003115-9 s Qualitätskontrolle (DE-588)4047968-7 s Arzneiform (DE-588)4068874-4 s Banker, Gilbert S. Sonstige oth Drugs and the pharmaceutical sciences 40 (DE-604)BV000002008 40 GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=001638436&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Modern pharmaceutics Drugs and the pharmaceutical sciences Biopharmacie Geneesmiddelen gtt Industrie pharmaceutique - Qualité - Contrôle Médicaments - Formes pharmaceutiques Pharmacocinétique Biopharmaceutics Drugs Dosage forms Pharmaceutical industry Quality control Pharmacokinetics Arzneimittel (DE-588)4003115-9 gnd Arzneiform (DE-588)4068874-4 gnd Qualitätskontrolle (DE-588)4047968-7 gnd Pharmazie (DE-588)4045705-9 gnd |
| subject_GND | (DE-588)4003115-9 (DE-588)4068874-4 (DE-588)4047968-7 (DE-588)4045705-9 |
| title | Modern pharmaceutics |
| title_auth | Modern pharmaceutics |
| title_exact_search | Modern pharmaceutics |
| title_full | Modern pharmaceutics ed. by Gilbert S. Banker |
| title_fullStr | Modern pharmaceutics ed. by Gilbert S. Banker |
| title_full_unstemmed | Modern pharmaceutics ed. by Gilbert S. Banker |
| title_short | Modern pharmaceutics |
| title_sort | modern pharmaceutics |
| topic | Biopharmacie Geneesmiddelen gtt Industrie pharmaceutique - Qualité - Contrôle Médicaments - Formes pharmaceutiques Pharmacocinétique Biopharmaceutics Drugs Dosage forms Pharmaceutical industry Quality control Pharmacokinetics Arzneimittel (DE-588)4003115-9 gnd Arzneiform (DE-588)4068874-4 gnd Qualitätskontrolle (DE-588)4047968-7 gnd Pharmazie (DE-588)4045705-9 gnd |
| topic_facet | Biopharmacie Geneesmiddelen Industrie pharmaceutique - Qualité - Contrôle Médicaments - Formes pharmaceutiques Pharmacocinétique Biopharmaceutics Drugs Dosage forms Pharmaceutical industry Quality control Pharmacokinetics Arzneimittel Arzneiform Qualitätskontrolle Pharmazie |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=001638436&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV000002008 |
| work_keys_str_mv | AT bankergilberts modernpharmaceutics |