Ciba Foundation Symposium on the Chemistry and Biology of Purines:
Saved in:
| Corporate Authors: | , |
|---|---|
| Format: | Conference Proceeding Book |
| Language: | English |
| Published: |
London
Churchill
1957
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| Series: | Ciba Foundation symposia
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XII, 327 S. Ill., graph. Darst. |
Staff View
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| 245 | 1 | 0 | |a Ciba Foundation Symposium on the Chemistry and Biology of Purines |c ed. G. E. W. Wolstenholme ... |
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Record in the Search Index
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| adam_text | CIBA FOUNDATION SYMPOSIUM if -
f ON THE : 11:
CHEMISTRY AND BIOLOGY ;j -
OF PURINES
s
Editors for the Ciba Foundation
GEW WOLSTENHOLME, OBE,MA,MB,B Ch
and
CECILIA M O CONNOR, B Sc
With 124 Illustrations
and structural formulae
Ifgfflftsm der
fe iL/:ori Zentrclbucherei
§3fl flessh-Haus
Erafikfurt/Main
LONDON
J amp;A CHURCHILL LTD
104 GLOUCESTER PLACE, W l
CONTENTS
Opening remarks
G M TIMMIS
Synthesis and properties of purines of potential biological
interest
by A BENDICH, A GINER-SOROLLA and J J Fox 3
Discussion: ALBERT, BENDICH, BERGEL, G B BROWN,
; COLLIER, DAVOLL, ELION, MASON, TAYLOR, TIMMIS, TODD 16
Some synthetic studies on purines and related heterocycles
by E C TAYLOR, T S OSDENE, E RICHTER and 0 VOGL 20
!! Discussion: ALBERT, BAKER, BENDICH, BERGEL, BREDERECK,
D M BROWN, G B BROWN, BUCHANAN, COLLIER, GREEN-
BERG, SCHMIDT, TAYI OR, TIMMIS 33
i:
Some new Ar- methylpu r ines
by GERTRUDE B ELION 39
The structure of the hydroxypurines investigated by O-
and A -methylation
by DJBROWN50
• ii Discussion: ALBERT, BADDILEY, BAKER, BENDICH, BERGEL,
BREDERECK, D J BROWN, D M BROWN, G B BROWN,
COLLIER, ELION, PJLEIDERER, TAYLOR, TODD, VARA-
JDARAJAN55
The spectra and structure of the monohydroxypurines
and other potentially tautomeric purines
by SFMASON60 li
i1
Short Communication:
The 7t- electron properties of purine calculated by the
iiC A O method
by SFMASON72
Discussion: ALBERT, BAKER, BENDICH, BERGEL, G B
I BROWN, COLLIER, EI I ON, GALTON, KENNER, KON, MASON,
TODD73
The degradation of uric acid by water under pressure
II by W PFLEIDERER 77
vii
PAGE
viii CONTENTS
PAGE
The 8-position in purines The chemical and biological
transformation of purines into pteridines
by AALBERT97
Discussion: ALBERT, BADDILEY, BAKER, BENDICH, BERGEL,
BREDERECK, G B BROWN, BUCHANAN, GREENBERG, KON,
PFLEIDERER,TAYLOR,TODD104
Ci/cfonucleosides
by D M BROWN Sir ALEXANDER TODD and S VARA-,
DARAJAN 108
Discussion: BADDILEY, BAKER, BENDICH, BERGEL, D M
BROWN, G B BROWN , TODD, VARADARAJAN 116
Stereochemistry of nucleoside synthesis
by B R BAKER 120
Discussion: ALBERT, BAKER, BENDICH, D M BROWN, G B
BROWN, KENNER, TODD, VARADARAJAN , 130
Synthetic chemical investigations related to the meta
bolism of purines /
by G M TIMMIS, I COOKE and RGW SPICKETT 134
Discussion: ALBERT, BAKER, BENDICH, G B BROWN, MASON,
TAYLOR, TIMMIS 142
The effects of potential antipurines on a purine-requiring
Strain of Escherichia coli
by HOJ COLLIER and PATRICIA L HUSKINSON 146
Discussion: BAKER, BERGEL, G B BROWN, BUCHANAN,
COLLIER, ELION, GREENBERG, HUTCHINGS, MATTHEWS,
WOODS156
The chemistry of new purines in the B12 series of vitamins
by E LESTER SMITH 160
Biological and microbiological activity of purine ana
logues of vitamin B12
by SKKON169
Discussion: ALBERT, BAKER, BENDICH, BERGEL, BUCHANAN,
KON, MATTHEWS, SMITH, TAYLOR, TODD, WOODS 173
Puromycin
by BLHUTCHINGS177
Discussion: ALBERT, BADDILEY, BAKER, BENDICH, BERGEL,
G B BROWN, BUCHANAN, COLLIER, GREENBERG, HUTCH
INGS, KON, TIMMIS 188
I I| CONTENTS ix
i ,i
j,|PAGE
! Chemical and biological behaviours of 9 - p-11 -ribofuranosy 1 -
I purine
III by G B BROWN M P GORDON, D I MAGRATII and
|J;A HAMPTON 192
I j Discussion: BADDILEY, BAKER, BENDICH, BERGEL, G B
J 1 BROWN, COLLIER, DAVOLL, HUTCHINGS, KON, TAYLOR 201
l! On the activation of the one-carbon unit for the bio
synthesis of purine nucleotides
|| 1 by G R GREENBKRG and L JAENICKE 204
The enzymatic synthesis of inosinic acid de novo
by J M BUCHANAN, J G FLAKS, S C HARTMAN, B ~
j|! LEVENBERG, L N LUKENS and L WARREN 233
I Discussion: ALBERT, BADDILEY, BAKER, G B BROWN,
j BUCHANAN, GREENBERG, SMITH, TAYLOR, TIMMIS, WOODS 252
J Enzymic control of purines by xanthine oxidase
| by F BERGEL, R C BRAY, A HADDOW and I LEWIN 256
J Discussion: ALBERT, BERGEL, G B BROWN, BUCHANAN,
I COLLIER, GREENBERG, HADDOW, HUTCHINGS, LEWIN 266
j The biological effects of 8-azapurines
| by REFMATTHEWS270
Iji
I| Discussion: ALBERT, BAKER, BENDICH, BERGEL, D M BROWN,
IJ BUCHANAN, COLLIER, ELION, GREENBERG, MATTHEWS,
SCHMIDT, TAYLOR, WOODS 283
Biochemical effects of 6-mercaptopurine
by GERTRUDE B ELION and G H HITCHINGS 286
Discussion: BAKER* G B BROWN, BUCHANAN, ELION, GREEN
BERG, KON, TAYLOR 295
The use of 6-mercaptopurine in the treatment of leukaemia
by DAGGALTON299
Ij Discussion: ALBERT, BENDICH, BERGEL, G B BROWN,
J|: BUCHANAN, COLLIER, DAVOLL, ELION, GALTON, GREENBERG,
KON, LEWIN, TIMMIS 306
I
j General Discussion
{J( BAKER, BENDICII, BERGEL, G B BROWN, BUCHANAN,
I I ELION, GREENBERG, KENNER, MASON, TAYLOR, TODD,
J SCHMIDT, VARADARAJAN, WOODS 308
jChairman s closing remarks
J A ALBERT 317
|
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| author_corporate | Symposium on The Chemistry and Biology of Purines London Ciba Foundation |
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| author_facet | Symposium on The Chemistry and Biology of Purines London Ciba Foundation |
| author_sort | Symposium on The Chemistry and Biology of Purines London |
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| dewey-full | 612.015 |
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| discipline | Biologie Medizin |
| format | Conference Proceeding Book |
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| illustrated | Illustrated |
| indexdate | 2024-07-09T15:37:23Z |
| institution | BVB |
| institution_GND | (DE-588)5163104-0 (DE-588)1003913-2 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-001256645 |
| oclc_num | 247859344 |
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| owner_facet | DE-355 DE-BY-UBR DE-20 DE-19 DE-BY-UBM |
| physical | XII, 327 S. Ill., graph. Darst. |
| publishDate | 1957 |
| publishDateSearch | 1957 |
| publishDateSort | 1957 |
| publisher | Churchill |
| record_format | marc |
| series2 | Ciba Foundation symposia |
| spelling | Symposium on The Chemistry and Biology of Purines 1956 London Verfasser (DE-588)5163104-0 aut Ciba Foundation Symposium on the Chemistry and Biology of Purines ed. G. E. W. Wolstenholme ... London Churchill 1957 XII, 327 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Ciba Foundation symposia Purin (DE-588)4176394-4 gnd rswk-swf (DE-588)1071861417 Konferenzschrift gnd-content Purin (DE-588)4176394-4 s DE-604 Wolstenholme, Gordon E. W. 1913-2004 Sonstige (DE-588)121827496 oth Ciba Foundation Verfasser (DE-588)1003913-2 aut HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=001256645&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Ciba Foundation Symposium on the Chemistry and Biology of Purines Purin (DE-588)4176394-4 gnd |
| subject_GND | (DE-588)4176394-4 (DE-588)1071861417 |
| title | Ciba Foundation Symposium on the Chemistry and Biology of Purines |
| title_auth | Ciba Foundation Symposium on the Chemistry and Biology of Purines |
| title_exact_search | Ciba Foundation Symposium on the Chemistry and Biology of Purines |
| title_full | Ciba Foundation Symposium on the Chemistry and Biology of Purines ed. G. E. W. Wolstenholme ... |
| title_fullStr | Ciba Foundation Symposium on the Chemistry and Biology of Purines ed. G. E. W. Wolstenholme ... |
| title_full_unstemmed | Ciba Foundation Symposium on the Chemistry and Biology of Purines ed. G. E. W. Wolstenholme ... |
| title_short | Ciba Foundation Symposium on the Chemistry and Biology of Purines |
| title_sort | ciba foundation symposium on the chemistry and biology of purines |
| topic | Purin (DE-588)4176394-4 gnd |
| topic_facet | Purin Konferenzschrift |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=001256645&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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