Sodium transport inhibitors: 14 tables
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Basel ; München [u.a.]
Karger
1988
|
| Schriftenreihe: | Progress in biochemical pharmacology
23 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIV, 161 S. zahlr. graph. Darst. |
| ISBN: | 3805547072 |
Internformat
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| 650 | 4 | |a Sodium - Transport physiologique - Congrès | |
| 650 | 4 | |a Adenosine triphosphatase |x Inhibitors |v Congresses | |
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| adam_text | 04 SODIUM TRANSPORT INHIBITORS VOLUME EDITORS G.S. STOKES, SYDNEY J.F.
MARWOOD, SYDNEY 54 FIGURES AND 14 TABLES, 1988 BASEL * MIINCHEN * PARIS
* LONDON * NEW YORK * NEW DELHI * SINGAPORE * TOKYO * SYDNEY CONTENTS
GENERAL INTRODUCTION XII SECTION I: DETECTION OF CIRCULATING SODIUM
TRANSPORT INHIBITORS DIFFICULTIES IN THE ISOLATION AND IDENTIFICATION OF
ENDOGENOUS OUABAIN-LIKE SUBSTANCES M.A. MIR, CARDIFF 1 INTRODUCTION 1
BACKGROUND 1 PROBLEMS IN EXTRACTION 2 PLASMA AS A SOURCE 3 URINE AS A
SOURCE 3 BRAIN AS A SOURCE 3 SOURCE OF OUABAIN-LIKE FACTORS 4
HYPOTHALAMIC CELL CULTURE MEDIUM AS A SOURCE 4 PROBLEMS WITH
IDENTIFICATION 5 CONCLUSION 6 REFERENCES 6 CHARACTERISTICS OF THE NA,
K-ATPASE INHIBITOR FROM HYPOTHALAMUS G.T. HAUPERT, JR., BOSTON, MASS 10
INTRODUCTION 10 RESULTS 11 PURIFICATION AND PARTIAL CHEMICAL
CHARACTERIZATION OF H I . . . . . . . . 11 CRITERIA FOR PHYSIOLOGICAL
SIGNIFICANCE 12 MECHANISMS OF INHIBITION OF NA, K-ATPASE BY HI 13
STUDIES OF HI INHIBITION OF NA*-PUMP ACTIVITY IN RENAL TUBULAR
EPITHELIAL CELLS 16 DISCUSSION 18 REFERENCES 19 CONTENTS VI SPECIES
SENSITIVITY OF THE SODIUM PUMP TO A CIRCULATING OUABAIN- LIKE INHIBITOR
IN ACUTE HYPERVOLEMIA AND DOCA HYPERTENSION: COMPARISON WITH OUABAIN
J.M. HAMLYN; M.D. ASHEN; B. FORREST; A.C. ROGOWSKI; R.J. WHITE,
BALTIMORE, MD 22 INTRODUCTION 22 MATERIALS AND METHODS 23 ACUTE BLOOD
VOLUME EXPANSION 23 CHRONIC BLOOD VOLUME EXPANSION 23 PREPARATION OF
HUMAN AND RAT RED CELLS 23 PREPARATION OF SERUM FOR ASSAY 24
PURIFICATION OF DIGITALIS-LIKE ACTIVITY 24 MISCELLANEOUS 24 RESULTS 25
DISCUSSION 28 CONCLUSIONS 32 REFERENCES 32 HUMORAL SODIUM-POTASSIUM PUMP
INHIBITOR IN REDUCED RENAL MASS-SALINE HYPERTENSIVE RATS M.B. PAMNANI;
F.J. HADDY, BETHESDA, MD 35 INTRODUCTION 35 PREPARATION OF REDUCED RENAL
MASS NORMOTENSIVE AND HYPERTENSIVE RATS, AND PROTOCOLS 36 BIOASSAYS FOR
SODIUM PUMP INHIBITING ACTIVITY IN PLASMA 37 RESULTS AND DISCUSSION 38
REFERENCES 42 AN NA + -K + -ATPASE INHIBITOR WHICH CIRCULATES IN RENAL
FAILURE BUT NOT IN ESSENTIAL HYPERTENSION G.S. STOKES; L.A. NORRIS; J.F.
MARWOOD; J.C. MONAGHAN; R.J. CATERSON, SYDNEY 46 INTRODUCTION 46
SUBJECTS AND METHODS 47 SUBJECTS 47 CLINICAL PROCEDURES 47 LABORATORY
PROCEDURES 47 STATISTICS 48 CONTENTS VII RESULTS 48 COMPARISON OF
SUBJECT GROUPS 48 STUDIES OF HAEMODIALYSIS AND ULTRAFILTRATION IN VIVO
49 SODIUM LOADING IN BORDERLINE HYPERTENSION 50 DISCUSSION 51
CONCLUSIONS 52 REFERENCES 52 SECTION II: INTERACTIONS OF SODIUM
TRANSPORT INHIBITION AND ATRIAL NATRIURETIC PEPTIDE ROLE OF ATRIAL
NATRIURETIC FACTOR IN REDUCED RENAL MASS SALINE HYPERTENSION M.B.
PAMNANI; F.J. HADDY, BETHESDA, MD 55 REVIEW 55 REFERENCES 59 NATRIURESIS
OF VOLUME EXPANSION AND ATRIAL FACTORS: CONTRASTS AND COMPARISONS A.Z.
GYORY;S. REDDY; D. KELLY; C. COCHINEAS, SYDNEY 61 INTRODUCTION 61
METHODS 62 SURGERY 62 MEASUREMENTS 62 EXPERIMENTAL PROTOCOLS 62 RESULTS
63 RIGHT KIDNEY (WITHOUT CEI) 63 RIGHT KIDNEY WITH CEI 66 LEFT KIDNEY 66
DISCUSSION 67 CONCLUSIONS 69 REFERENCES 70 ENDOGENOUS NA,K-ATPASE
INHIBITOR(S) AND ATRIAL NATRIURETIC PEPTIDES: ARE THEY INTERRELATED?
G.T. HAUPERT, JR., BOSTON, MASS 71 REVIEW 71 REFERENCES 74 CONTENTS VIII
SECTION III: FACTORS INFLUENCING CATION TRANSPORT IN ERYTHROCYTES
CONFOUNDING FACTORS IN THE STUDY OF MEMBRANE PUMP ABNOR- MALITIES IN
ESSENTIAL HYPERTENSION AND PREGNANCY-INDUCED HYPERTENSION J.A. MILLAR;
P.M. BRAMLEY; P.D. WILSON, DUNEDIN, NEW ZEALAND 77 INTRODUCTION 77
METHODS 78 PATIENTS 78 LABORATORY METHODS 78 STATISTICAL METHODS 78
RESULTS 79 ESSENTIAL HYPERTENSION 79 PREGNANCY-INDUCED HYPERTENSION 80
DISCUSSION 80 REFERENCES 82 METHODS OF ASSESSMENT OF ERYTHROCYTE NA + -K
+ -ATPASE FUNCTION IN NORMAL AND HYPERTENSIVE PREGNANCY E.D.M. GALLERY;
J. ROWE; M. HAWKINS, SYDNEY 84 INTRODUCTION 84 MATERIALS AND METHODS 84
SUBJECTS 84 ANALYTICAL METHODS 85 STATISTICAL METHODS 85 RESULTS 85
DISCUSSION 86 CONCLUSIONS 89 REFERENCES . 90 INDIVIDUAL VARIABILITY IN
MEMBRANE SODIUM TRANSPORT DURING SALT LOADING * EVIDENCE AGAINST THE
PRODUCTION OF A NA + -K + -ATPASE INHIBITOR IN HYPERTENSION T.J.B.
MATING;R.W.L. SIEBERS, WELLINGTON 91 INTRODUCTION 91 METHODS 92 SUBJECTS
92 STUDY DESIGN 92 MEASUREMENTS 92 RESULTS 93 BLOOD PRESSURE AND HEART
RATE 93 CONTENTS IX URINE SODIUM EXCRETION AND WEIGHT 93 MEMBRANE SODIUM
TRANSPORT INDICES 94 HOMOLOGOUS PLASMA/CELL INCUBATION STUDIES 94
DISCUSSION 96 REFERENCES 99 INDEPENDENCE OF NA + -LI + COUNTERTRANSPORT
FROM DIETARY SALT INTAKE J. FRISCH;J. KINDLER; G. KASPERS; H.G.
SIEBERTH, AACHEN 101 INTRODUCTION 101 MATERIAL AND METHODS 102 RESULTS
102 DISCUSSION 103 CONCLUSIONS 105 REFERENCES 106 ATP DEPENDENCE OF
ACTIVE CALCIUM TRANSPORT IN RED BLOOD CELLS Y.-H. XU;B.D. ROUFOGALIS,
SYDNEY 107 INTRODUCTION 107 MATERIALS AND METHODS 108 DETERMINATION OF
CA 2 *-ATPASE ACTIVITY IN INTACT RED BLOOD CELLS . . . 108 ATP DEPLETION
BY METABOLIC STARVATION 109 RESULTS 110 ATP DEPENDENCE OF CA 2 *-ATPASE
ACTIVITY IN INTACT RED BLOOD CELLS . 110 CALCIUM DEPENDENCE OF CA 2
*-ATPASE ACTIVITY AT VARIOUS ATP CONCENTRATIONS ILL ATP DEPENDENCE OF CA
2 * EFFLUX FROM INTACT RED BLOOD CELLS ILL DISCUSSION ILL CONCLUSION 116
REFERENCES 116 SECTION IV: FACTORS INFLUENCING CONTRACTILITY OF VASCULAR
SMOOTH MUSCLE VASOREACTIVE EFFECTS OF HYPOTHALAMIC SODIUM TRANSPORT
INHIBITOR M.A. MIR.K. MORGAN; S. CHAPPELL.M. LEWIS; G. SPURLOCK;P.
COLLINS; M. LEWIS, CARDIFF 119 INTRODUCTION 119 MATERIALS AND METHODS
120 CONTENTS X REAGENTS 120 PERFUSION CULTURE SYSTEM 120 ISOLATION AND
PURIFICATION OF ASTI 120 AORTIC STRIP PREPARATIONS 121 CALCIUM UPTAKE
STUDIES 121 STATISTICAL ANALYSIS 121 RESULTS 122 VASOACTIVE EFFECTS OF
ASTI 122 EFFECT ON CALCIUM UPTAKE 122 DISCUSSION 123 CONCLUSIONS 124
REFERENCES 125 EFFECT OF NA/K-ATPASE INHIBITION ON TRANSMURALLY
STIMULATED VASCULAR CONTRACTIONS M. HABEREY; G. KLOSS; M. BUSE; R.
BECKMANN, WEST-BERLIN 128 INTRODUCTION 128 MATERIAL AND METHODS 128
RESULTS 130 CARDIAC GLYCOSIDES 130 NATRIURETIC FRACTION 132 DISCUSSION
134 CONCLUSION 134 REFERENCES 135 RELAXANT EFFECTS OF ATRIAL NATRIURETIC
POLYPEPTIDE ON GUINEA PIG TRACHEAL SMOOTH MUSCLE H. WATANABE; K. TAKAGI;
T. SATAKE, NAGOYA 136 INTRODUCTION 136 MATERIALS AND METHODS 136
EXPERIMENT 1 136 EXPERIMENT 2 137 STATISTICAL ANALYSIS 138 RESULTS 138
EXPERIMENT 1. RELAXANT EFFECTS OF ANP 138 EXPERIMENT 2. TISSUE CYCLIC
GMP AND CYCLIC AMP LEVELS 139 DISCUSSION 139 REFERENCES 141 CONTENTS XI
MECHANISMS INFLUENCING SODIUM ENTRY TO CULTURED VASCULAR SMOOTH MUSCLE
P.J. LITTLE; P.L. WEISSBERG; E.J. CRAGOE JR.; A. BOBIK, WEST POINT 142
INTRODUCTION 142 MATERIALS AND METHODS 143 CULTURE OF VASCULAR SMOOTH
MUSCLE 143 MEASUREMENT OF CELL NA* CONTENT 143 DETERMINATION OF 22 NA*
INFLUX RATES 143 MATERIALS 143 RESULTS 144 EXTRACELLULAR PH AND NA*
INFLUX 144 INTRACELLULAR PH AND NA* INFLUX 144 DEPENDENCE OF NA* INFLUX
ON PROTEIN KINASE ACTIVITY 145 DISCUSSION 145 CONCLUSION 147
ACKNOWLEDGEMENTS 147 REFERENCES 148 EFFECT OF CHANGES IN INTRACELLULAR
PH ON THE CONTRACTILITY OF RAT RESTISTANCE VESSELS C. AALKJAER; M.J.
MULVANY, AARHUS 150 INTRODUCTION 150 METHODS 150 PREPARATION AND
SOLUTIONS 150 PH, AND ISOMETRIC CONTRACTIONS 151 RESULTS 151
NORADRENALINE-STIMULATED VESSELS 154 K-PSS-STIMULATED VESSELS 154
DISCUSSION 155 CONCLUSION 157 REFERENCES 157 SUBJECT INDEX 159
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| series | Progress in biochemical pharmacology |
| series2 | Progress in biochemical pharmacology |
| spelling | Sodium transport inhibitors 14 tables vol. ed. G. S. Stokes ... Basel ; München [u.a.] Karger 1988 XIV, 161 S. zahlr. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Progress in biochemical pharmacology 23 Adénosine-triphosphatase - Inhibiteurs - Congrès Facteur natriurétique atrial - Congrès Hypertension artérielle - Physiopathologie - Congrès Sodium - Transport physiologique - Congrès Adenosine triphosphatase Inhibitors Congresses Atrial Natriuretic Factor Congresses Atrial natriuretic peptides Congresses Hypertension Pathophysiology Congresses Ion Channels Congresses Ion Exchange Congresses Sodium Physiological transport Congresses Sodium metabolism Congresses Sodium-Potassium-Exchanging ATPase Congresses Natriumpumpe (DE-588)4171274-2 gnd rswk-swf Inhibitor (DE-588)4027007-5 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content (DE-588)1071861417 Konferenzschrift gnd-content Natriumpumpe (DE-588)4171274-2 s Inhibitor (DE-588)4027007-5 s DE-604 Stokes, Gordon S. Sonstige oth Progress in biochemical pharmacology 23 (DE-604)BV000002187 23 GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=000520212&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Sodium transport inhibitors 14 tables Progress in biochemical pharmacology Adénosine-triphosphatase - Inhibiteurs - Congrès Facteur natriurétique atrial - Congrès Hypertension artérielle - Physiopathologie - Congrès Sodium - Transport physiologique - Congrès Adenosine triphosphatase Inhibitors Congresses Atrial Natriuretic Factor Congresses Atrial natriuretic peptides Congresses Hypertension Pathophysiology Congresses Ion Channels Congresses Ion Exchange Congresses Sodium Physiological transport Congresses Sodium metabolism Congresses Sodium-Potassium-Exchanging ATPase Congresses Natriumpumpe (DE-588)4171274-2 gnd Inhibitor (DE-588)4027007-5 gnd |
| subject_GND | (DE-588)4171274-2 (DE-588)4027007-5 (DE-588)4143413-4 (DE-588)1071861417 |
| title | Sodium transport inhibitors 14 tables |
| title_auth | Sodium transport inhibitors 14 tables |
| title_exact_search | Sodium transport inhibitors 14 tables |
| title_full | Sodium transport inhibitors 14 tables vol. ed. G. S. Stokes ... |
| title_fullStr | Sodium transport inhibitors 14 tables vol. ed. G. S. Stokes ... |
| title_full_unstemmed | Sodium transport inhibitors 14 tables vol. ed. G. S. Stokes ... |
| title_short | Sodium transport inhibitors |
| title_sort | sodium transport inhibitors 14 tables |
| title_sub | 14 tables |
| topic | Adénosine-triphosphatase - Inhibiteurs - Congrès Facteur natriurétique atrial - Congrès Hypertension artérielle - Physiopathologie - Congrès Sodium - Transport physiologique - Congrès Adenosine triphosphatase Inhibitors Congresses Atrial Natriuretic Factor Congresses Atrial natriuretic peptides Congresses Hypertension Pathophysiology Congresses Ion Channels Congresses Ion Exchange Congresses Sodium Physiological transport Congresses Sodium metabolism Congresses Sodium-Potassium-Exchanging ATPase Congresses Natriumpumpe (DE-588)4171274-2 gnd Inhibitor (DE-588)4027007-5 gnd |
| topic_facet | Adénosine-triphosphatase - Inhibiteurs - Congrès Facteur natriurétique atrial - Congrès Hypertension artérielle - Physiopathologie - Congrès Sodium - Transport physiologique - Congrès Adenosine triphosphatase Inhibitors Congresses Atrial Natriuretic Factor Congresses Atrial natriuretic peptides Congresses Hypertension Pathophysiology Congresses Ion Channels Congresses Ion Exchange Congresses Sodium Physiological transport Congresses Sodium metabolism Congresses Sodium-Potassium-Exchanging ATPase Congresses Natriumpumpe Inhibitor Aufsatzsammlung Konferenzschrift |
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