Transdermal controlled systemic medications:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York u.a.
Dekker
1987
|
| Schriftenreihe: | Drugs and the pharmaceutical sciences
31 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XVI, 440 S. Ill. |
| ISBN: | 0824777603 |
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| 650 | 4 | |a Pharmaceutical technology | |
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| adam_text | TRANSDERMAL CONTROLLED SYSTEMIC MEDICATIONS EDITED BY YIEW.CHIEN
CONTROLLED DRUG-DELIVERY RESEARCH CENTER RUTGERS-THE STATE UNIVERSITY OF
NEW JERSEY PISCATAWAY, NEW JERSEY MARCEL DEKKER, INC. NEW YORK AND BASEL
CONTENTS PREFACE HI CONTRIBUTORS V 1. ADVANCES IN TRANSDERMAL SYSTEMIC
MEDICATION 1 YIE W. CHIEN I. INTRODUCTION 1 II. THE SKIN: SITE OF
TRANSDERMAL DRUG ADMINISTRATION 2 III. EARLY DEVELOPMENT OF TRANSDERMAL
DRUG DELIVERY 6 IV. RECENT DEVELOPMENTS IN TRANSDERMAL DRUG DELIVERY 14
REFERENCES 21 DEVELOPMENT AND PRECLINICAL ASSESSMENTS OF . TRANSDERMAL
THERAPEUTIC SYSTEMS 2. DEVELOPMENTAL CONCEPTS AND PRACTICE IN
TRANSDERMAL THERAPEUTIC SYSTEMS 25 YIE W. CHIEN I. INTRODUCTION 25 II.
FUNDAMENTALS OF RATE-CONTROLLED TRANSDERMAL DRUG DELIVERY 26 III.
APPROACHES TO THE DEVELOPMENT OF TRANSDERMAL THERAPEUTIC SYSTEMS 31 IV.
KINETIC EVALUATIONS OF TRANSDERMAL THERAPEUTIC SYSTEMS 44 V. FORMULATION
DESIGN AND OPTIMIZATION 56 XI XII I CONTENTS VI. ENHANCEMENT OF
TRANSDERMAL CONTROLLED DRUG DELIVERY 59 VII. GENERIC PROGRAM FOR
TRANSDERMAL DRUG DELIVERY SYSTEM DEVELOPMENT 75 REFERENCES 77 3.
ALTERATIONS IN SKIN PERMEABILITY 83 EUGENE R. COOPER I. INTRODUCTION 83
II. ENHANCEMENT RECOGNITION 84 III. MEMBRANE ALTERATIONS 86 IV.
REDUCTION OF PENETRATION 90 V. SUMMARY 90 REFERENCES 90 4.
PRESSURE-SENSITIVE ADHESIVES: SCIENCE AND ENGINEERING 93 MARTIN C.
MUSOLF I. II. III. IV. INTRODUCTION PRESSURE-SENSITIVE ADHESIVES
PRESSURE-SENSITIVE ADHESIVES FOR TRANSDERMAL APPLICATIONS SUMMARY
REFERENCES 93 96 104 111 112 5. POLYMERIC MATERIALS: ASSESSMENT OF SKIN
BIOCOMPATIBILITY 113 KEVIN S. WEADOCK, JAMES M. PACHENCE, RICHARD A.
BERG, AND FREDERICK H. SILVER I. INTRODUCTION 113 II. BIOCOMPATIBILITY
TESTING OF POLYMERS 114 III. CELLULAR RESPONSE TO POLYMERS 117 IV.
POLYMER DEGRADATION 118 V. CONCLUSIONS 120 REFERENCES 120 6. DESIGN AND
CALIBRATION OF IN VITRO PERMEATION APPARATUS 127 KAKUJI TOJO I.
INTRODUCTION 127 II. DESIGN OF IN VITRO SKIN PERMEATION APPARATUS 129
III. METHOD FOR CHARACTERIZING THE HYDRODYNAMICS OF IN VITRO SYSTEMS 137
IV. CORRELATION EQUATION FOR MASS TRANSFER COEFFICIENT 141 CONTENTS I
XIII V. EFFECT OF THE DIFFUSION BOUNDARY LAYER ON DRUG PERMEATION 143
VI. CALCULATION OF INTRINSIC RATE OF PERMEATION 151 VII. EFFECT OF
TEMPERATURE ON DRUG PERMEATION 154 VIII. CONCLUSION 156 REFERENCES 157
7. IN VITRO EVALUATIONS OF TRANSDERMAL DRUG DELIVERY 159 YIH-CHAIN HUANG
I. INTRODUCTION 159 II. IN VITRO SKIN PERMEATION KINETICS 160 III.
CONCLUSION 177 REFERENCES 177 8. IN VIVO EVALUATIONS OF TRANSDERMAL DRUG
DELIVERY 179 RICHARD H. GUY, JONATHAN HADGRAFT, ROBERT S. HINZ, KATHLEEN
V. ROSKOS, AND DANIEL A. W. BUCKS I. INTRODUCTION 179 II. ANIMAL MODELS
181 III. HUMAN EXPERIMENTATION 192 IV. KINETIC MODELING OF TRANSDERMAL
DRUG DELIVERY 204 V. SUMMARY 215 REFERENCES 216 CLINICAL ASSESSMENTS OF
TRANSDERMAL THERAPEUTIC SYSTEMS 9. TRANSDERMAL DELIVERY OF NITROGLYCERIN
I 227 NATHANIEL REICHEK I. INTRODUCTION ; 227 II. HISTORY OF TRANSDERMAL
NITROGLYCERIN V 228 III. PROBLEMS IN ASSESSMENT OF LONG-ACTING NITRATES
FOR ANGINA PROPHYLAXIS 229 IV. ANTIANGINAL EFFECT OF NITROGLYCERIN
OINTMENT 231 V. ANTIANGINAL EFFECT OF NITROGLYCERIN PATCHES 233 VI.
ATTENUATION OF ANTIANGINAL EFFECTS OF OTHER NITRATES 238 VII. STUDIES IN
PROGRESS 240 VIII. FUTURE DIRECTIONS 241 IX. CONCLUSIONS 241- REFERENCES
242 XIV I CONTENTS 10. TRANSDERMAL DELIVERY OF NITROGLYCERIN II 245 V -*
D ZENANA E. REZAKOVIC I. INTRODUCTION 245 II. CLINICAL TRIALS OF
NITROGLYCERIN PATCHES IN CORONARY ARTERY DISEASE 246 III. HEMODYNAMIC
TRIALS OF NITROGLYCERIN PATCHES 284 IV. MULTICENTER STUDIES OF THE
NITROGLYCERIN PATCH IN EUROPE 295 V. OLD AND NEW DATA ABOUT
NITROGLYCERIN PATCH EFFICACY 301 VI. CONCLUSIONS 309 REFERENCES 311 11.
TRANSDERMAL DELIVERY OF CLONIDINE 321 G. S. PERLMUTTER, ESTER PARAN,
BONITA FALKNER, CAROL M. BIES, T. FAGAN, ROBERT R. CHASE, AND DAVID T.
LOWENTHAL I. INTRODUCTION 321 II. MECHANISM OF ACTION 322 III.
PHARMACOKINETICS 322 IV. PHARMACOLOGICAL EFFECTS 323 V. ADVERSE EFFECTS
326 VI. CONCLUSIONS 329 REFERENCES 330 12. TRANSDERMAL DELIVERY OF
BUPRANOLOL 333 INGE WEISS, HANS-MICHAEL WOLFF, GUNTER CORDES, AND WILLI
CAWELLO I. INTRODUCTION 333 II. TRANSDERMAL ABSORPTION OF BUPRANOLOL IN
RABBITS 334 III. PHARMACOKINETIC AND PHARMACODYNAMIC STUDIES IN HUMAN
VOLUNTEERS V 339 IV. EVALUATION OF PHARMACODYNAMIC EFFECTS COMPARED TO
PERORAL PROPRANOLOL 343 V. SUMMARY 345 REFERENCES 345 ENGINEERING AND
MANUFACTURING OF TRANSDERMAL THERAPEUTIC SYSTEMS 13. DEVELOPMENT OF
PROCESSES AND EQUIPMENT FOR RATE-CONTROLLED TRANSDERMAL THERAPEUTIC
SYSTEMS 349 JOHN W. DOHNER I. INTRODUCTION 349 II. TRANSDERMAL PRODUCTS
DEVELOPED AT ALZA 349 CONTENTS I XV III. MANUFACTURING PROCESSES AND
EQUIPMENT 351 IV. ENGINEERING DEVELOPMENT OF TRANSDERMAL SYSTEMS 354 V.
COMMERCIAL PRODUCTION OF TRANSDERMAL SYSTEMS 362 VI. SUMMARY 363
REFERENCES 364 14. DEVELOPMENT OF PROCESSES AND TECHNOLOGY FOR ADHESIVE-
TYPE TRANSDERMAL THERAPEUTIC SYSTEMS 365 HANS-MICHAEL WOLFF, HANS RAINER
HOFFMANN, AND GUNTER CORDES I. INTRODUCTION 365 II. GALENICAL STRUCTURE
OF THE DEPONIT SYSTEM 366 III. MANUFACTURING PROCESS 368 IV. COMMENTS ON
GALENICAL DESIGN 373 REFERENCES 378 15. PRODUCT DEVELOPMENT AND
TECHNOLOGY TRANSFER FOR TRANSDERMAL THERAPEUTIC SYSTEMS 379 DAVID J.
BOVA, VALERIE N. AHMUTY, ROBERT L. CIRRITO, KAREN O TOOLE HOLMES, K.
KASPER, CAROLINE LAPRADE, R. LAPRADE, GUSTAV A. MAAG, JUAN A. MANTELLE,
JOHN A. MECARTY, J. MIRANDA, FRANKIE A. MORTON, AND STEVEN SABLOTSKY I.
INTRODUCTION 379 II. RESEARCH PHASE 380 III. PRODUCT DEVELOPMENT AND
TECHNOLOGY TRANSFER 381 IV. CONCLUSION 396 REGULATORY REQUIREMENTS AMONG
INTERNATIONAL HEALTH AUTHORITIES 16. REGULATORY CONSIDERATIONS IN
TRANSDERMAL DRUG DELIVERY SYSTEMS IN THE UNITED STATES 399 VINOD P. SHAH
AND JEROME P. SKELLY I. INTRODUCTION 399 II. BIOPHARMACEUTIC
CONSIDERATIONS 401 III. REGULATORY REQUIREMENTS 408 IV. GENERIC VERSIONS
OF TRANSDERMAL DRUG PRODUCTS 410 17. REGULATORY APPROVAL OF TRANSDERMAL
THERAPEUTIC SYSTEMS IN THE UNITED KINGDOM 411 PAUL ADAMS I. INTRODUCTION
411 II. PRODUCT LICENSE APPLICATIONS 412 XVI I CONTENTS III. ABRIDGED
APPLICATIONS 412 IV. CONCLUSION 417 18. REGULATORY APPROVAL OF
TRANSDERMAL THERAPEUTIC SYSTEMS IN JAPAN 419 TSUNEJI NAGAI AND YOSHIHARU
MACHIDA I. INTRODUCTION 419 II. APPLICATION REQUIREMENTS FOR APPROVAL OF
NEW PRESCRIPTION DRUGS IN JAPAN 420 III. SCIENTIFIC DATA REQUIRED FOR
APPROVAL OF TRANSDERMAL THERAPEUTIC SYSTEMS 423 IV. PROCEDURE AND TIME
NEEDED FOR APPROVAL 429 V. REGULATORY POLICY IN OTHER ASIAN COUNTRIES
429 REFERENCE 430 INDEX 431
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| illustrated | Illustrated |
| indexdate | 2024-07-09T15:18:21Z |
| institution | BVB |
| isbn | 0824777603 |
| language | English |
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| physical | XVI, 440 S. Ill. |
| publishDate | 1987 |
| publishDateSearch | 1987 |
| publishDateSort | 1987 |
| publisher | Dekker |
| record_format | marc |
| series | Drugs and the pharmaceutical sciences |
| series2 | Drugs and the pharmaceutical sciences |
| spelling | Transdermal controlled systemic medications ed. by Yie W. Chien New York u.a. Dekker 1987 XVI, 440 S. Ill. txt rdacontent n rdamedia nc rdacarrier Drugs and the pharmaceutical sciences 31 Médicaments - Administration par voie transdermique Médicaments-retard Techniques pharmaceutiques Administration, Cutaneous Drugs Controlled release Pharmaceutical technology Transdermal medication Kontrollierte Wirkstofffreisetzung (DE-588)4165181-9 gnd rswk-swf Kutane Applikation (DE-588)4123924-6 gnd rswk-swf Kontrollierte Wirkstofffreisetzung (DE-588)4165181-9 s Kutane Applikation (DE-588)4123924-6 s DE-604 Chien, Yie W. Sonstige oth Drugs and the pharmaceutical sciences 31 (DE-604)BV000002008 31 GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=000450104&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Transdermal controlled systemic medications Drugs and the pharmaceutical sciences Médicaments - Administration par voie transdermique Médicaments-retard Techniques pharmaceutiques Administration, Cutaneous Drugs Controlled release Pharmaceutical technology Transdermal medication Kontrollierte Wirkstofffreisetzung (DE-588)4165181-9 gnd Kutane Applikation (DE-588)4123924-6 gnd |
| subject_GND | (DE-588)4165181-9 (DE-588)4123924-6 |
| title | Transdermal controlled systemic medications |
| title_auth | Transdermal controlled systemic medications |
| title_exact_search | Transdermal controlled systemic medications |
| title_full | Transdermal controlled systemic medications ed. by Yie W. Chien |
| title_fullStr | Transdermal controlled systemic medications ed. by Yie W. Chien |
| title_full_unstemmed | Transdermal controlled systemic medications ed. by Yie W. Chien |
| title_short | Transdermal controlled systemic medications |
| title_sort | transdermal controlled systemic medications |
| topic | Médicaments - Administration par voie transdermique Médicaments-retard Techniques pharmaceutiques Administration, Cutaneous Drugs Controlled release Pharmaceutical technology Transdermal medication Kontrollierte Wirkstofffreisetzung (DE-588)4165181-9 gnd Kutane Applikation (DE-588)4123924-6 gnd |
| topic_facet | Médicaments - Administration par voie transdermique Médicaments-retard Techniques pharmaceutiques Administration, Cutaneous Drugs Controlled release Pharmaceutical technology Transdermal medication Kontrollierte Wirkstofffreisetzung Kutane Applikation |
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