Development of drugs and modern medicines: a conference to honour Prof. Arnold H. Beckett
Saved in:
| Format: | Book |
|---|---|
| Language: | German |
| Published: |
Weinheim
VCH u.a.
1986
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| Series: | Ellis Horwood series in biomedicine
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | X, 669 S. |
| ISBN: | 3527265090 0895735571 |
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Record in the Search Index
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DEVELOPMENT OF DRUGS AND MODERN MEDICINES A CONFERENCE TO HONOUR
PROFESSOR ARNOLD H. BECKETT EDITED BY J.W. GORROD, G.G. GIBSON AND M.
MITCHARD VCH MIR ELU * HORWOOD * VSJL-1. HJ INTENWRTIONAL PUBS**N IN
IDENCE AN IN TDCNC* AND TECHNOTOGY TABLE OF CONTENTS PREFACE 1 PROFILE
OF PROFESSOR ARNOLD H.BECKETT, OBE 3 PART I. DRUG DESIGN FORTY YEARS OF
MEDICINAL CHEMISTRY * REFLECTIONS, PERSPECTIVES AND EXPECTATIONS 7 A. H.
BECKETT 1 DEVELOPMENTS IN CENTRAL ANALGESICS: 1951-1985 34 A. F. CASEY 2
NEW DEVELOPMENTS IN MONOAMINE OXIDASE INHIBITORS . 40 R. T. COUTTS,
G. B. BAKER, T. J. DANIELSON 3 GUANIDINES IN MEDICINAL CHEMISTRY 49 J.
V. GREENHILL 4 SYNTHETIC PEPTIDES AS DRUG RECEPTOR MODELS: DESIGNING
CALMODULIN ANTAGONISTS 63 R. E. REID 5 DESIGN OF GASTRIC ACID SECRETION
INHIBITORS 72 A. CANAS-RODRIGUEZ 6 THERMODYNAMIC FUNCTIONS FOR
DISSOCIATIONS OF ACIDS OF 5,5-DISUBSTI- TUTED BARBITURIC ACIDS * THEIR
SIGNIFICANCE IN STRUCTURE -REACTIVITY RELATIONSHIPS 80 R. H. MCKEOWN, R.
J. PRANKERD, O. WONG 7 RING CHLORINATED 3,4-DIMETHOXYPHENYLTHANOLAMINES
90 G. J. SQUIER, D. P. VENTER, D. W. OLIVER VI TABLE OF CONTENTS 8
BIOLOGICALLY ACTIVE COMPOUNDS FROM BUDDLEJA 95 P. J. HOUGHTON 9 THE
ACTIVE PRINCIPLE OF FEVERFEW 100 P. J. HYLANDS, D. M. HYLANDS FART D.
PHARMACOLOGICAL EVALUATION 10 BEYOND THE RECEPTOR: HOW STIMULATORY
SIGNALS ARE TRANSMITTED IN THE CELL 107 M. A. BEAVEN 11 THE MODE OF
ACTION OF NEUROLEPTIC DRUGS 117 P.JENNER 12 BIOSYNTHESIS AND INHIBITION
OF EICOSANOIDS: THERAPEUTIC RELEVANCE 136 J. A. SALMON 13 STEROIDS *
DRUG RESPONSE AND METABOLISM 149 P. KOUROUNAKIS 14 HYSTERESIS CURVES IN
CLINICAL AND PHARMACOLOGY: DEMONSTRATION OF TOLERANCE AND OTHER
PHENOMENA 161 S. H. CURRY 15 NGP 1-01: ELECTROPHYSIOLOGICAL STUDIES ON A
NOVEL CALCIUM ANTAGONIST . .174 C. J. VAN DER SCHYF, G. J. SQUIER, W. A.
COETZEE PART M. DRUG AND METABOLITE ANALYSIS 16 TRACE ANALYSIS OF DRUGS
AND METABOLITES 181 K. K. MIDHA, S. F. COOPER, G. MCKAY 17 ELECTRON SPIN
RESONANCE AS A TOOL TO STUDY DRUG MECHANISMS AND TOXICITY 197 C. F.
CHIGNELL 18 RADIOIMMUNOASSAY TECHNIQUE AS USED IN DRUG DEVELOPMENT 208
E. V. B. SHENOY 19 DETERMINATION OF FLUPHENAZINE IN PLASMA BY HIGH
PRESSURE LIQUID CHROMATOGRAPHY WITH ELECTROCHEMICAL DETECTION 226 B. W.
HADZIJA 20 A FACILE GAS CHROMATOGRAPHIC METHOD FOR RESOLVING THE
ENANTIOMERS OF SEVERAL NON-STEROIDAL ANT-INFLAMMATORY DRUGS 232 R. T.
COUTTS, F. M. PASUTTO, F. JAMALI, N. SINGH TABLE OF CONTENTS VII 21 A
NOVEL TECHNIQUE FOR THE SIMULTANEOUS DETERMINATION OF AZATHIOPRINE AND
ITS MAIN METABOLITE 6-MERCAPTOPURINE USING REVERSE-PHASE HIGH PRESSURE
LIQUID CHROMATOGRAPHY 237 E. M. NABI, A. ROSEN 22 STABILITY INDICATING
HIGH PRESSURE LIQUID CHROMATOGRAPHY METHOD FOR CHLORPROMAZINE 244 L. S.
CHAGONDA. J. S. MILLERSHIP PART IV. DRUG METABOLISM 23 CYTOCHROME P-450:
FROM BIOPHYSICS TO PHARMACOLOGY 253 G. G. GIBSON 24 THE CONJUGATION
REACTIONS AS INTERFACES BETWEEN DRUG METABOLISM AND INTERMEDIARY
BIOCHEMISTRY 267 J. CALDWELL, J. C. HOBART, I. A. COTGREAVE 25
MECHANISMS OF CYTOCHROME P-450-CATALYZED REACTIONS 278 W. F. TRAGER 26
CEREBRAL AND OTHER EXTRAHEPATIC SITES OF DRUG METABOLISM 288 B. TESTA 27
STEREOSELECTIVE METABOLISM AND THE FATE OF FENFUIRAMINE IN ANIMALS AND
MAN 298 D. B. CAMPBELL, R. P. RICHARDS, S. CACCIA, S. GARATTINI 28 THE
INFLUENCE OF INCREASING ANIMAL AGE ON THE IN VITRO METABOLISM OF
IMIPRAMINE 312 C. C. ASGILL, J. W. GORROD 29 MICROSOMAL FORMATION OF
AMIDES FROM SECONDARY AROMATIC AMINES . . .318 N. J. GOODERHAM, J. W.
GORROD 30 IV-DEALKYLATION, A ROUTE IN THE METABOLISM OF AMODIAQUINE IN
MAN 324 F. A. OGUNBONA, A. B. FABAYO 31 SPECTRAL STUDIES ON THE
INTERACTION OF IV-ETHYL-P-METHOXY-P-(3'-TRIFLUORO- METHYLPHENYL)
ETHYLAMINE (SKF 40652A) AND SOME OF ITS METABOLITES WITH RABBIT LIVER
MICROSOMES 331 A. H. BECKETT, N. N. RAHMAN 32 IMPAIRED CELL-FREE
TRANSLATION OF HEPATIC MESSENGER RNA FROM MICE TREATED WITH
POLYRIBOINOSINIC ACID: POLYRIBOCYTIDYLIC ACID. RATIONALE FOR THE
DEPRESSION OF CYTOCHROME P-450 BY INTERFERON INDUCERS 339 N. J.
GOODERHAM, G^ J. MANNERING VIII TABLE OF CONTENTS PART V. DRUG DELIVERY
SYSTEMS 33 PERSPECTIVES IN DRUG DELIVERY AND DRUG TARGETTING 347 T. M.
JONES 34 INTESTINAL DRUG ABSORPTION AND CONTROLLED RELEASE 361 D. C.
TAYLOR 35 DRUG RELEASE KINETICS AND MICROENCAPSULATION DESIGN 374 M.
DONBROW 36 THE SIGNIFICANCE OF FORMULATION IN DRUG BIOAVAILABILITY. A
STUDY WITH CIMETIDINE TABLETS 386 N. H. CHOULIS 37 SUSTAINED RELEASE OF
DRUGS USING MICROENCAPSULATION 391 J. R. NIXON 38 IN VITRO RELEASE
CHARACTERISTICS OF THEOPHYLLINE-ACRYLIC RESIN GRANULES. . 400 V. H.
DAWES, W. F. MERICAN 39 GELATIN-ACACIA COACERVATE FILMS: PREPARATION AND
PERMEATION TO SODIUM CHLORIDE 409 K. T. WONG, J. R. NIXON 40 THE
SIGNIFICANCE OF CONTACT ANGLES MEASURED ON SURFACES WHICH HAVE UNDERGONE
PLASTIC DEFORMATION 421 G. BUCKTON, J. M. NEWTON 41 COACERVATE
TECHNIQUES FOR THE PREPARATION OF MICROCAPSULES OF POSSIBLE
PHARMACEUTICAL APPLICATION 425 J. R. NIXON, M. S. HARRIS * PART VI.
PHARMACOKINETIC STUDIES 42 PHYSIOLOGIC PHARMACOKINETIC MODELS 437 M.
ROWLAND 43 PHARMACOKINETICS IN GERIATRICS .451 E. J. TRIGGS 44 GENETIC
VARIABILITY IN PHARMACOKINETICS 462 G. T. TUCKER, M. S. LENNARD, P. R.
JACKSON, H. F. WOODS 45 GENETIC POLYMORPHISM OF MEPHENYTOIN
HYDROXYLATION IN MAN 474 G. R. WILKINSON 46 SOME REALIZATIONS IN
PHARMACOKINETIC ANALYSIS 494 D. P. VAUGHAN TABLE OF CONTENTS IX 47
COMPUTER SIMULATION OF GASTROINTESTINAL ABSORPTION 503 D. CUTLER, S.
FIRMER 48 THE RELATIONSHIP BETWEEN THEOPHYLLINE THERAPEUTIC EFFICACY AND
ITS PLASMA CONCENTRATIONS IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY
DISEASE TREATED WITH A SUSTAINED-RELEASE PREPARATION OF THEOPHYLLINE . .
.512 M. POKRAJAC, V. BOSNJAK, D. AGBABA, M. STEVANOVIC, V. M. VARAGID,
M. ZUGID 49 PLASMA LEVELS OF FOSFESTROL AND ITS MAIN METABOLITES
FOLLOWING ADMI- NISTRATION OF FOSFESTROL TO PATIENTS WITH METASTASIZING
PROSTATIC CARCI- NOMA 517 H. OELSCHLAGER, D. ROTHLEY 50 THE METABOLISM
AND KINETICS OF DOXAZOSIN IN MAN, RAT, MOUSE AND DOG. . 527 N. J.
CUSSANS, B. KAYE, J. K. FAULKNER, D. A. STOPHER 51 A WEIGHTED
LEAST-SQUARES METHOD FOR FITTING CALIBRATION LINES TO HETEROSCEDASTIC
DATA OBTAINED USING A SIMPLE HIGH PRESSURE LIQUID CHROMATOGRAPHY ASSAY
534 E. DOYLE PART VII. DRUG TOXICITY, INTERACTIONS AND ABUSE 52
EXPERIMENTAL MODELS OF DRUG INTERACTIONS 543 D. J. TEMPLE 53 INTERACTION
OF MAN AND CHEMICALS 554 A. E. ROBINSON 54 PHILOSOPHY AND PRACTICE OF
CONTROL OF DRUG ABUSE IN SPORT. PART I 563 A. H. BECKETT 55 PHILOSOPHY
AND PRACTICE OF CONTROL OF DRUG ABUSE IN SPORT. PART II SCIENTIFIC
CONSIDERATIONS 573 D. A. COWAN 56 IMMUNOLOGICAL INTERVENTION IN DIGOXIN
HANDLING AND TOXICITY 579 D. S. HEWICK, N. M. GRIFFITHS, M. ANDREWS, I.
H. STEVENSON 57 RAPID ASSESSMENT OF ATP, ADP AND AMP FROM PRIMARY
CULTURES OF RAT HEPATOCYTES BY ISOCRATIC REVERSE-PHASE HIGH PRESSURE
LIQUID CHROMA- TOGRAPHY FOR STUDIES ON DRUG TOXICITY 591 M. MAZZEI, G.
GALLO, A. BALBI, A. ERMILI, G. ROMA 58 METABOLISM OF 4-AMINOBIPHENYL BY
ISOLATED HEPATOCYTES OF VARIOUS MAMMALIAN SPECIES 599 S. D. JATOE, J. W.
GORROD 59 COMPARATIVE MACROSCOPIC AND HISTOLOGICAL EFFECTS OF DIFFERENT
OXPRENO- LOL AND INDOMETHACIN FORMULATIONS ON THE DEAL MUCOSA OF THE PIG
609 V. A. JOHN, P. D. SIBBONS, P. A. SHOTTON, P. LLOYD TABLE OF CONTENTS
PART VIII. CLINICAL EVALUATION AND REGULATORY AFFAIRS 60 REGULATORY
REQUIREMENTS FOR THE PRECLINICAL SAFETY TESTING OF PHARMA- CEUTICALS
.U*:.,. . . .615 S. R. WALKER, C. E. LUMLEY 61 CLINICAL EVALUATION IN
DRUG DEVELOPMENT. . 627 R. N. BOYES 62 ASPECTS OF INTERNATIONAL DRUG
REGISTRATION 631 M. MITCHARD 63 BIOPHARMACEUTICAL AND DRUG METABOLISM
STUDIES IN THE DEVELOPMENT OF PHARMACEUTICALS 644 L. G. BROOKES INDEX
660 |
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| id | DE-604.BV000605901 |
| illustrated | Not Illustrated |
| indexdate | 2025-01-28T13:01:32Z |
| institution | BVB |
| isbn | 3527265090 0895735571 |
| language | German |
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| physical | X, 669 S. |
| publishDate | 1986 |
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| record_format | marc |
| series2 | Ellis Horwood series in biomedicine |
| spelling | Development of drugs and modern medicines a conference to honour Prof. Arnold H. Beckett ed. by J. W. Gorrod ... Weinheim VCH u.a. 1986 X, 669 S. txt rdacontent n rdamedia nc rdacarrier Ellis Horwood series in biomedicine Chimie pharmaceutique Médicaments - Métabolisme Médicaments Pharmacocinétique Drugs Metabolism Pharmaceutical Preparations Congresses Pharmaceutical chemistry Pharmacokinetics Arzneimittelentwicklung (DE-588)4143176-5 gnd rswk-swf Arzneimittelforschung (DE-588)4003120-2 gnd rswk-swf (DE-588)4016928-5 Festschrift gnd-content (DE-588)1071861417 Konferenzschrift 1985 London gnd-content Arzneimittelentwicklung (DE-588)4143176-5 s DE-604 Arzneimittelforschung (DE-588)4003120-2 s Gorrod, John W. Sonstige oth GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=000376913&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Development of drugs and modern medicines a conference to honour Prof. Arnold H. Beckett Chimie pharmaceutique Médicaments - Métabolisme Médicaments Pharmacocinétique Drugs Metabolism Pharmaceutical Preparations Congresses Pharmaceutical chemistry Pharmacokinetics Arzneimittelentwicklung (DE-588)4143176-5 gnd Arzneimittelforschung (DE-588)4003120-2 gnd |
| subject_GND | (DE-588)4143176-5 (DE-588)4003120-2 (DE-588)4016928-5 (DE-588)1071861417 |
| title | Development of drugs and modern medicines a conference to honour Prof. Arnold H. Beckett |
| title_auth | Development of drugs and modern medicines a conference to honour Prof. Arnold H. Beckett |
| title_exact_search | Development of drugs and modern medicines a conference to honour Prof. Arnold H. Beckett |
| title_full | Development of drugs and modern medicines a conference to honour Prof. Arnold H. Beckett ed. by J. W. Gorrod ... |
| title_fullStr | Development of drugs and modern medicines a conference to honour Prof. Arnold H. Beckett ed. by J. W. Gorrod ... |
| title_full_unstemmed | Development of drugs and modern medicines a conference to honour Prof. Arnold H. Beckett ed. by J. W. Gorrod ... |
| title_short | Development of drugs and modern medicines |
| title_sort | development of drugs and modern medicines a conference to honour prof arnold h beckett |
| title_sub | a conference to honour Prof. Arnold H. Beckett |
| topic | Chimie pharmaceutique Médicaments - Métabolisme Médicaments Pharmacocinétique Drugs Metabolism Pharmaceutical Preparations Congresses Pharmaceutical chemistry Pharmacokinetics Arzneimittelentwicklung (DE-588)4143176-5 gnd Arzneimittelforschung (DE-588)4003120-2 gnd |
| topic_facet | Chimie pharmaceutique Médicaments - Métabolisme Médicaments Pharmacocinétique Drugs Metabolism Pharmaceutical Preparations Congresses Pharmaceutical chemistry Pharmacokinetics Arzneimittelentwicklung Arzneimittelforschung Festschrift Konferenzschrift 1985 London |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=000376913&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT gorrodjohnw developmentofdrugsandmodernmedicinesaconferencetohonourprofarnoldhbeckett |